PMC:7152911 / 78627-79407 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T169","span":{"begin":249,"end":257},"obj":"Body_part"},{"id":"T170","span":{"begin":388,"end":399},"obj":"Body_part"},{"id":"T171","span":{"begin":388,"end":392},"obj":"Body_part"},{"id":"T172","span":{"begin":599,"end":604},"obj":"Body_part"}],"attributes":[{"id":"A169","pred":"fma_id","subj":"T169","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A170","pred":"fma_id","subj":"T170","obj":"http://purl.org/sig/ont/fma/fma280556"},{"id":"A171","pred":"fma_id","subj":"T171","obj":"http://purl.org/sig/ont/fma/fma256135"},{"id":"A172","pred":"fma_id","subj":"T172","obj":"http://purl.org/sig/ont/fma/fma9670"}],"text":"Centrifugation can be used as a density gradient-based separation principle for concentrating target pathogens within a sample. In cases where the target species exhibits similar density to background species, the approach is often implemented with antibody-functionalized beads. This technique is commonly employed in applications requiring pathogen detection in complex matrices (e.g., body fluids). Centrifugation-based separation techniques can also potentially be applied to microfluidic-based biosensing platforms. For example, Lee et al. utilized centrifugal microfluidics to process a whole blood sample for subsequent analysis using ELISA (Lee et al. 2009), suggesting that this approach could be extended to electrochemical biosensor-based assays for pathogen detection."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T17","span":{"begin":599,"end":604},"obj":"Body_part"}],"attributes":[{"id":"A17","pred":"uberon_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"}],"text":"Centrifugation can be used as a density gradient-based separation principle for concentrating target pathogens within a sample. In cases where the target species exhibits similar density to background species, the approach is often implemented with antibody-functionalized beads. This technique is commonly employed in applications requiring pathogen detection in complex matrices (e.g., body fluids). Centrifugation-based separation techniques can also potentially be applied to microfluidic-based biosensing platforms. For example, Lee et al. utilized centrifugal microfluidics to process a whole blood sample for subsequent analysis using ELISA (Lee et al. 2009), suggesting that this approach could be extended to electrochemical biosensor-based assays for pathogen detection."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T519","span":{"begin":30,"end":31},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T520","span":{"begin":118,"end":119},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T521","span":{"begin":388,"end":399},"obj":"http://purl.obolibrary.org/obo/UBERON_0006314"},{"id":"T522","span":{"begin":591,"end":592},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T523","span":{"begin":593,"end":604},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T524","span":{"begin":593,"end":604},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"}],"text":"Centrifugation can be used as a density gradient-based separation principle for concentrating target pathogens within a sample. In cases where the target species exhibits similar density to background species, the approach is often implemented with antibody-functionalized beads. This technique is commonly employed in applications requiring pathogen detection in complex matrices (e.g., body fluids). Centrifugation-based separation techniques can also potentially be applied to microfluidic-based biosensing platforms. For example, Lee et al. utilized centrifugal microfluidics to process a whole blood sample for subsequent analysis using ELISA (Lee et al. 2009), suggesting that this approach could be extended to electrochemical biosensor-based assays for pathogen detection."}

{"project":"LitCovid-sentences","denotations":[{"id":"T643","span":{"begin":0,"end":127},"obj":"Sentence"},{"id":"T644","span":{"begin":128,"end":279},"obj":"Sentence"},{"id":"T645","span":{"begin":280,"end":401},"obj":"Sentence"},{"id":"T646","span":{"begin":402,"end":520},"obj":"Sentence"},{"id":"T647","span":{"begin":521,"end":659},"obj":"Sentence"},{"id":"T648","span":{"begin":660,"end":780},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Centrifugation can be used as a density gradient-based separation principle for concentrating target pathogens within a sample. In cases where the target species exhibits similar density to background species, the approach is often implemented with antibody-functionalized beads. This technique is commonly employed in applications requiring pathogen detection in complex matrices (e.g., body fluids). Centrifugation-based separation techniques can also potentially be applied to microfluidic-based biosensing platforms. For example, Lee et al. utilized centrifugal microfluidics to process a whole blood sample for subsequent analysis using ELISA (Lee et al. 2009), suggesting that this approach could be extended to electrochemical biosensor-based assays for pathogen detection."}

{"project":"2_test","denotations":[{"id":"32364936-19458861-7713104","span":{"begin":660,"end":664},"obj":"19458861"}],"text":"Centrifugation can be used as a density gradient-based separation principle for concentrating target pathogens within a sample. In cases where the target species exhibits similar density to background species, the approach is often implemented with antibody-functionalized beads. This technique is commonly employed in applications requiring pathogen detection in complex matrices (e.g., body fluids). Centrifugation-based separation techniques can also potentially be applied to microfluidic-based biosensing platforms. For example, Lee et al. utilized centrifugal microfluidics to process a whole blood sample for subsequent analysis using ELISA (Lee et al. 2009), suggesting that this approach could be extended to electrochemical biosensor-based assays for pathogen detection."}