PMC:7152911 / 137670-138817 JSONTXT

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T242","span":{"begin":83,"end":84},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T243","span":{"begin":510,"end":513},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T244","span":{"begin":530,"end":531},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T245","span":{"begin":594,"end":595},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T246","span":{"begin":812,"end":813},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"The elimination of sample preparation steps from biosensor-based assays represents a significant advantage relative to traditional bioanalytical techniques (Johnson and Mutharasan, 2012) and is an important advantage and consideration for single-use biosensors and remote biosensing applications based on portable low-cost platforms. Sample preparation-free protocols can improve measurement confidence, repeatability, and reduce TTR, which are important aspects of healthcare decision-making. For example, it has been shown that a reduction in turnaround time for diagnostic assays could have a positive effect on clinical treatment outcomes (Davenport et al. 2017; Sin et al. 2014). When sample preparation is required, integrated alternatives to manual techniques, such as microfluidic processes, may provide a new path toward achieving rapid and robust pathogen detection. For example, separation and pre-concentration steps have been increasingly examined for integration with microfluidic-based biosensor platforms to reduce the number of steps, materials needed, and required technical personnel, and thus TTR (Bunyakul and Baeumner, 2014)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T1119","span":{"begin":0,"end":333},"obj":"Sentence"},{"id":"T1120","span":{"begin":334,"end":493},"obj":"Sentence"},{"id":"T1121","span":{"begin":494,"end":660},"obj":"Sentence"},{"id":"T1122","span":{"begin":661,"end":677},"obj":"Sentence"},{"id":"T1123","span":{"begin":678,"end":684},"obj":"Sentence"},{"id":"T1124","span":{"begin":685,"end":876},"obj":"Sentence"},{"id":"T1125","span":{"begin":877,"end":1147},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The elimination of sample preparation steps from biosensor-based assays represents a significant advantage relative to traditional bioanalytical techniques (Johnson and Mutharasan, 2012) and is an important advantage and consideration for single-use biosensors and remote biosensing applications based on portable low-cost platforms. Sample preparation-free protocols can improve measurement confidence, repeatability, and reduce TTR, which are important aspects of healthcare decision-making. For example, it has been shown that a reduction in turnaround time for diagnostic assays could have a positive effect on clinical treatment outcomes (Davenport et al. 2017; Sin et al. 2014). When sample preparation is required, integrated alternatives to manual techniques, such as microfluidic processes, may provide a new path toward achieving rapid and robust pathogen detection. For example, separation and pre-concentration steps have been increasingly examined for integration with microfluidic-based biosensor platforms to reduce the number of steps, materials needed, and required technical personnel, and thus TTR (Bunyakul and Baeumner, 2014)."}

{"project":"2_test","denotations":[{"id":"32364936-23101954-7713211","span":{"begin":181,"end":185},"obj":"23101954"},{"id":"32364936-28248946-7713212","span":{"begin":661,"end":665},"obj":"28248946"},{"id":"32364936-24524681-7713213","span":{"begin":678,"end":682},"obj":"24524681"},{"id":"32364936-25558994-7713214","span":{"begin":1141,"end":1145},"obj":"25558994"}],"text":"The elimination of sample preparation steps from biosensor-based assays represents a significant advantage relative to traditional bioanalytical techniques (Johnson and Mutharasan, 2012) and is an important advantage and consideration for single-use biosensors and remote biosensing applications based on portable low-cost platforms. Sample preparation-free protocols can improve measurement confidence, repeatability, and reduce TTR, which are important aspects of healthcare decision-making. For example, it has been shown that a reduction in turnaround time for diagnostic assays could have a positive effect on clinical treatment outcomes (Davenport et al. 2017; Sin et al. 2014). When sample preparation is required, integrated alternatives to manual techniques, such as microfluidic processes, may provide a new path toward achieving rapid and robust pathogen detection. For example, separation and pre-concentration steps have been increasingly examined for integration with microfluidic-based biosensor platforms to reduce the number of steps, materials needed, and required technical personnel, and thus TTR (Bunyakul and Baeumner, 2014)."}