PMC:7152526 / 2022-6430
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 69 | 166-176 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 70 | 337-355 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 71 | 464-483 | Chemical | denotes | lopinavir/ritonavir | MESH:C558899 |
| 72 | 540-546 | Chemical | denotes | oxygen | MESH:D010100 |
| 73 | 118-123 | Disease | denotes | fever | MESH:D005334 |
| 74 | 128-133 | Disease | denotes | cough | MESH:D003371 |
| 75 | 266-274 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 85 | 957-975 | Gene | denotes | C-reactive protein | Gene:1401 |
| 86 | 977-980 | Gene | denotes | CRP | Gene:1401 |
| 87 | 1198-1211 | Gene | denotes | interleukin 6 | Gene:3569 |
| 88 | 1213-1217 | Gene | denotes | IL-6 | Gene:3569 |
| 89 | 642-649 | Species | denotes | patient | Tax:9606 |
| 90 | 690-696 | Chemical | denotes | oxygen | MESH:D010100 |
| 91 | 668-675 | Disease | denotes | dyspnea | MESH:D004417 |
| 92 | 928-939 | Disease | denotes | lymphopenia | MESH:D008231 |
| 93 | 1088-1105 | Disease | denotes | blood coagulation | MESH:D001778 |
| 99 | 1667-1670 | Gene | denotes | CRP | Gene:1401 |
| 100 | 1685-1689 | Gene | denotes | IL-6 | Gene:3569 |
| 101 | 1481-1500 | Chemical | denotes | lopinavir/ritonavir | MESH:C558899 |
| 102 | 1502-1520 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 103 | 1445-1449 | Disease | denotes | ARDS | MESH:D012128 |
| 115 | 2699-2716 | Species | denotes | Novel Coronavirus | Tax:2697049 |
| 116 | 2915-2922 | Species | denotes | patient | Tax:9606 |
| 117 | 2606-2616 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 118 | 1812-1830 | Chemical | denotes | methylprednisolone | MESH:D008775 |
| 119 | 1794-1798 | Disease | denotes | ARDS | MESH:D012128 |
| 120 | 1960-1968 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 121 | 2002-2010 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 122 | 2022-2027 | Disease | denotes | fever | MESH:D005334 |
| 123 | 2029-2034 | Disease | denotes | cough | MESH:D003371 |
| 124 | 2039-2048 | Disease | denotes | pneumonia | MESH:D011014 |
| 125 | 2717-2725 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 134 | 3175-3178 | Gene | denotes | CRP | Gene:1401 |
| 135 | 3183-3187 | Gene | denotes | IL-6 | Gene:3569 |
| 136 | 3126-3133 | Species | denotes | patient | Tax:9606 |
| 137 | 3378-3388 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 138 | 3604-3614 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 139 | 3646-3653 | Species | denotes | patient | Tax:9606 |
| 140 | 3084-3090 | Chemical | denotes | oxygen | MESH:D010100 |
| 141 | 3064-3069 | Disease | denotes | fever | MESH:D005334 |
| 144 | 3831-3834 | Gene | denotes | CRP | Gene:1401 |
| 145 | 3950-3997 | Species | denotes | severe acute respiratory syndrome coronavirus-2 | Tax:2697049 |
| 148 | 4096-4099 | Gene | denotes | CRP | Gene:1401 |
| 149 | 4102-4120 | Gene | denotes | C-reactive protein | Gene:1401 |
| 151 | 4400-4407 | Species | denotes | patient | Tax:9606 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T10 | 382-387 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
| T11 | 458-462 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T12 | 776-781 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
| T13 | 858-863 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T14 | 876-892 | Body_part | denotes | white blood cell | http://purl.org/sig/ont/fma/fma62852 |
| T15 | 888-892 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T16 | 968-975 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T17 | 1088-1093 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T18 | 1198-1211 | Body_part | denotes | interleukin 6 | http://purl.org/sig/ont/fma/fma264829 |
| T19 | 1198-1209 | Body_part | denotes | interleukin | http://purl.org/sig/ont/fma/fma86578 |
| T20 | 1609-1614 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
| T21 | 1719-1733 | Body_part | denotes | arterial blood | http://purl.org/sig/ont/fma/fma83066 |
| T22 | 1888-1894 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T23 | 2127-2133 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T24 | 2159-2164 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T25 | 2196-2202 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T26 | 2265-2270 | Body_part | denotes | veins | http://purl.org/sig/ont/fma/fma63814 |
| T27 | 2348-2353 | Body_part | denotes | Blood | http://purl.org/sig/ont/fma/fma9670 |
| T28 | 2579-2585 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T29 | 2617-2620 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T30 | 2621-2629 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T31 | 2633-2639 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T32 | 2726-2729 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T33 | 2817-2820 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T34 | 2857-2863 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T35 | 3052-3058 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T36 | 3303-3308 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
| T37 | 3351-3355 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T38 | 3424-3427 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T39 | 3438-3441 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T40 | 3473-3477 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T41 | 3578-3584 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T42 | 3893-3896 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T43 | 3907-3910 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T44 | 3942-3946 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T45 | 4001-4007 | Body_part | denotes | sputum | http://purl.org/sig/ont/fma/fma312401 |
| T46 | 4113-4120 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T47 | 4130-4135 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
| T48 | 4189-4195 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T49 | 4251-4257 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 382-387 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T2 | 458-462 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T3 | 776-781 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T4 | 858-863 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T5 | 882-887 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T6 | 1088-1093 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T7 | 1609-1614 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T8 | 1719-1733 | Body_part | denotes | arterial blood | http://purl.obolibrary.org/obo/UBERON_0013755 |
| T9 | 1728-1733 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T10 | 2159-2164 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T11 | 2348-2353 | Body_part | denotes | Blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T12 | 3303-3308 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T13 | 3351-3355 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T14 | 4001-4007 | Body_part | denotes | sputum | http://purl.obolibrary.org/obo/UBERON_0007311 |
| T15 | 4130-4135 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T32 | 166-174 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T33 | 266-274 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T34 | 568-570 | Disease | denotes | he | http://purl.obolibrary.org/obo/MONDO_0017319 |
| T35 | 928-939 | Disease | denotes | lymphopenia | http://purl.obolibrary.org/obo/MONDO_0003783 |
| T36 | 1445-1449 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T37 | 1548-1550 | Disease | denotes | he | http://purl.obolibrary.org/obo/MONDO_0017319 |
| T38 | 1794-1798 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T39 | 1960-1968 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T40 | 2002-2010 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T41 | 2039-2048 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T42 | 2606-2614 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T43 | 2717-2725 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T44 | 2803-2805 | Disease | denotes | OD | http://purl.obolibrary.org/obo/MONDO_0017178 |
| T45 | 3378-3386 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T46 | 3604-3612 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T47 | 3950-3997 | Disease | denotes | severe acute respiratory syndrome coronavirus-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T48 | 3950-3983 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T19 | 7-8 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T20 | 28-30 | http://purl.obolibrary.org/obo/CLO_0054055 | denotes | 71 |
| T21 | 92-94 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T22 | 380-381 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T23 | 382-387 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
| T24 | 458-462 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T25 | 458-462 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T26 | 776-781 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
| T27 | 858-863 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T28 | 858-863 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T29 | 864-869 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tests |
| T30 | 882-887 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T31 | 888-892 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T32 | 1088-1093 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T33 | 1088-1093 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T34 | 1106-1111 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tests |
| T35 | 1198-1211 | http://purl.obolibrary.org/obo/PR_000001393 | denotes | interleukin 6 |
| T36 | 1242-1244 | http://purl.obolibrary.org/obo/CLO_0008426 | denotes | pg |
| T37 | 1332-1339 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T38 | 1609-1614 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
| T39 | 1634-1638 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
| T40 | 1697-1699 | http://purl.obolibrary.org/obo/CLO_0008426 | denotes | pg |
| T41 | 1719-1727 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | arterial |
| T42 | 1719-1727 | http://www.ebi.ac.uk/efo/EFO_0000814 | denotes | arterial |
| T43 | 1728-1733 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T44 | 1728-1733 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T45 | 1888-1894 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T46 | 1913-1914 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T47 | 1915-1919 | http://purl.obolibrary.org/obo/UBERON_0003101 | denotes | male |
| T48 | 1915-1919 | http://www.ebi.ac.uk/efo/EFO_0000970 | denotes | male |
| T49 | 2127-2133 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T50 | 2147-2150 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T51 | 2159-2164 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T52 | 2159-2164 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T53 | 2196-2202 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T54 | 2265-2270 | http://purl.obolibrary.org/obo/UBERON_0001638 | denotes | veins |
| T55 | 2265-2270 | http://www.ebi.ac.uk/efo/EFO_0000816 | denotes | veins |
| T56 | 2305-2310 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tests |
| T57 | 2348-2353 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | Blood |
| T58 | 2348-2353 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | Blood |
| T59 | 2579-2585 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T60 | 2633-2639 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T61 | 2857-2863 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T62 | 3052-3058 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T63 | 3118-3120 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T64 | 3224-3226 | http://purl.obolibrary.org/obo/CLO_0008426 | denotes | pg |
| T65 | 3257-3259 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T66 | 3301-3302 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T67 | 3303-3308 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
| T68 | 3351-3355 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T69 | 3351-3355 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T70 | 3473-3477 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T71 | 3578-3584 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T72 | 3664-3665 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T73 | 3790-3791 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T74 | 3860-3861 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T75 | 3942-3946 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T76 | 4130-4135 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
| T77 | 4189-4195 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T78 | 4251-4257 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T2 | 337-355 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T3 | 464-483 | Chemical | denotes | lopinavir/ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
| T4 | 464-473 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
| T5 | 474-483 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
| T6 | 540-546 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
| T7 | 690-696 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
| T8 | 968-975 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T9 | 1161-1170 | Chemical | denotes | aspartate | http://purl.obolibrary.org/obo/CHEBI_132943|http://purl.obolibrary.org/obo/CHEBI_29995|http://purl.obolibrary.org/obo/CHEBI_72314 |
| T12 | 1213-1215 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T14 | 1481-1500 | Chemical | denotes | lopinavir/ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
| T15 | 1481-1490 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
| T16 | 1491-1500 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
| T17 | 1502-1520 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T18 | 1535-1546 | Chemical | denotes | antibiotics | http://purl.obolibrary.org/obo/CHEBI_33281 |
| T19 | 1685-1687 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T21 | 1812-1830 | Chemical | denotes | methylprednisolone | http://purl.obolibrary.org/obo/CHEBI_6888 |
| T22 | 1915-1919 | Chemical | denotes | male | http://purl.obolibrary.org/obo/CHEBI_30780 |
| T23 | 1920-1925 | Chemical | denotes | donor | http://purl.obolibrary.org/obo/CHEBI_17891 |
| T24 | 2165-2170 | Chemical | denotes | donor | http://purl.obolibrary.org/obo/CHEBI_17891 |
| T25 | 2289-2294 | Chemical | denotes | donor | http://purl.obolibrary.org/obo/CHEBI_17891 |
| T26 | 2412-2417 | Chemical | denotes | Donor | http://purl.obolibrary.org/obo/CHEBI_17499|http://purl.obolibrary.org/obo/CHEBI_17891 |
| T28 | 2508-2511 | Chemical | denotes | IDL | http://purl.obolibrary.org/obo/CHEBI_132933 |
| T29 | 2546-2548 | Chemical | denotes | CO | http://purl.obolibrary.org/obo/CHEBI_17245 |
| T30 | 3084-3090 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
| T31 | 3183-3185 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T33 | 4113-4120 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3 | 191-212 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | reverse transcription |
| T4 | 199-212 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
| T5 | 1088-1105 | http://purl.obolibrary.org/obo/GO_0007596 | denotes | blood coagulation |
| T6 | 1094-1105 | http://purl.obolibrary.org/obo/GO_0050817 | denotes | coagulation |
| T7 | 4021-4042 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | reverse transcription |
| T8 | 4029-4042 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T17 | 0-6 | Sentence | denotes | Case 1 |
| T18 | 7-134 | Sentence | denotes | A previously healthy 71-year-old man visited the Community Health Center on February 22, presenting 12 days of fever and cough. |
| T19 | 135-275 | Sentence | denotes | He underwent an examination of SARS-CoV-2 via real-time reverse transcription polymerase chain reaction (rRT-PCR) and diagnosed as COVID-19. |
| T20 | 276-379 | Sentence | denotes | He admitted to the local public medical center and 400 mg of hydroxychloroquine once daily was started. |
| T21 | 380-520 | Sentence | denotes | A chest radiograph obtained on day 2 showed mild opacities in the right lower lung, lopinavir/ritonavir 400 mg/100 mg twice daily was added. |
| T22 | 521-613 | Sentence | denotes | However, on day 3, oxygen demand increased, so he transferred to the tertiary-care hospital. |
| T23 | 614-775 | Sentence | denotes | At the time of arrival, the patient had no subjective dyspnea under 4 L/min oxygen flow via nasal cannula, but the respiratory rate was over 30 times per minute. |
| T24 | 776-849 | Sentence | denotes | Chest radiographs demonstrated rapidly aggravated bilateral infiltration. |
| T25 | 850-956 | Sentence | denotes | Routine blood tests found white blood cell (WBC) count at 3.53 × 103/µL, with lymphopenia of 0.4 × 103/µL. |
| T26 | 957-1051 | Sentence | denotes | C-reactive protein (CRP) and lactic dehydrogenase (LDH) elevated up to 59.7 mg/L and 814 IU/L. |
| T27 | 1052-1184 | Sentence | denotes | Routine chemistry, electrolyte, and blood coagulation tests revealed no abnormalities except mildly elevated aspartate transaminase. |
| T28 | 1185-1248 | Sentence | denotes | The level of interleukin 6 (IL-6) was increased as 101.3 pg/mL. |
| T29 | 1249-1358 | Sentence | denotes | Serial bacterial culture and polymerase chain reaction (PCR) for other respiratory viruses were all negative. |
| T30 | 1359-1450 | Sentence | denotes | Intubation and mechanical ventilator care were started according to the management of ARDS. |
| T31 | 1451-1622 | Sentence | denotes | Despite the continuous use of lopinavir/ritonavir, hydroxychloroquine and empirical antibiotics, he remained febrile with aggravated oxygenation profiles and chest images. |
| T32 | 1623-1704 | Sentence | denotes | Laboratory test showed further elevation of CRP (172.6 mg/L), IL-6 (208.2 pg/mL). |
| T33 | 1705-1799 | Sentence | denotes | On day 9, the arterial blood gas analysis showed PaO2/FiO2 of 86, consistent with severe ARDS. |
| T34 | 1800-1863 | Sentence | denotes | Intravenous methylprednisolone (1 mg/kg/day daily) was started. |
| T35 | 1864-1981 | Sentence | denotes | On day 10, convalescent plasma was obtained from a male donor in his 20s who had recovered from COVID-19 for 21 days. |
| T36 | 1982-2143 | Sentence | denotes | He was diagnosed as COVID-19 presenting fever, cough and pneumonia, however, showed complete recovery and didn’t have any symptom at the time of plasma donation. |
| T37 | 2144-2271 | Sentence | denotes | He has met the blood donor eligibility criteria for plasma donation, including age, weight, reasonable-sized antecubital veins. |
| T38 | 2272-2411 | Sentence | denotes | Also, allogeneic donor screening tests, defined by enforcement rules of the Blood Management Act in Korea, were acceptable for transfusion. |
| T39 | 2412-2600 | Sentence | denotes | Donor apheresis was performed with Spectra Optia apheresis system (CMNC software; Spectra Optia IDL Tubing set; Terumo BCT, Lakewood, CO, USA), 500 mL of convalescent plasma was collected. |
| T40 | 2601-2852 | Sentence | denotes | Anti-SARS-CoV-2 IgG antibody in plasma was measured by enzyme-linked immunosorbent assay (ELISA) (Novel Coronavirus COVID-19 IgG ELISA kit; Epitope Diagnostics, San Diego, CA, USA) and optical density (OD) ratio for IgG was 0.586 (cut-off value 0.22). |
| T41 | 2853-2944 | Sentence | denotes | The plasma was divided into two doses and administered to the patient at 12 hours interval. |
| T42 | 2945-2981 | Sentence | denotes | Each dose was given over for 1 hour. |
| T43 | 2982-3059 | Sentence | denotes | No adverse reaction occurred after the administration of convalescent plasma. |
| T44 | 3060-3121 | Sentence | denotes | The fever subsided, and oxygen demand decreased since day 11. |
| T45 | 3122-3300 | Sentence | denotes | The patient's condition much improved with decreased CRP and IL-6 to normal range (5.7 mg/L and < 1.5 pg/mL, respectively), and on day 18, PaO2/FiO2 increased up to 300 (Fig. 1). |
| T46 | 3301-3377 | Sentence | denotes | A chest X-ray revealed further resolution of both lung infiltrates (Fig. 2). |
| T47 | 3378-3603 | Sentence | denotes | SARS-CoV-2 was quantified by detection of the RNA-dependent RNA polymerase region of the ORF1b gene on rRT-PCR, the value of cycle threshold (Ct) changed from 24.98 on day 10 to 33.96 on day 20 after plasma infusion (Fig. 1). |
| T48 | 3604-3641 | Sentence | denotes | SARS-CoV-2 was negative after day 26. |
| T49 | 3642-3748 | Sentence | denotes | The patient underwent a tracheostomy and currently, is successfully weaned from the mechanical ventilator. |
| T50 | 3749-4095 | Sentence | denotes | Fig. 1 Case 1, responses to treatment. (A) Timelines of changes in PaO2/FiO2 and CRP during hospitalization. (B) Timelines of detection of the RNA-dependent RNA polymerase region of the ORF1b gene of severe acute respiratory syndrome coronavirus-2 in sputum by real-time reverse transcription polymerase chain reaction; cycle threshold is shown. |
| T51 | 4096-4121 | Sentence | denotes | CRP = C-reactive protein. |
| T52 | 4122-4205 | Sentence | denotes | Fig. 2 Chest X-rays of Case 1 taken before and after convalescent plasma infusion. |
| T53 | 4206-4274 | Sentence | denotes | Taken on day 7, just before the convalescent plasma infusion (left). |
| T54 | 4275-4351 | Sentence | denotes | Taken on day 13 shows marked improvement of bilateral infiltrations (right). |
| T55 | 4352-4408 | Sentence | denotes | The images are published under agreement of the patient. |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T5 | 118-123 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T6 | 128-133 | Phenotype | denotes | cough | http://purl.obolibrary.org/obo/HP_0012735 |
| T7 | 668-675 | Phenotype | denotes | dyspnea | http://purl.obolibrary.org/obo/HP_0002094 |
| T8 | 928-939 | Phenotype | denotes | lymphopenia | http://purl.obolibrary.org/obo/HP_0001888 |
| T9 | 2022-2027 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T10 | 2029-2034 | Phenotype | denotes | cough | http://purl.obolibrary.org/obo/HP_0012735 |
| T11 | 2039-2048 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T12 | 3064-3069 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T13 | 3351-3367 | Phenotype | denotes | lung infiltrates | http://purl.obolibrary.org/obo/HP_0002113 |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T41 | 40-43 | NCBITaxon:9606 | denotes | man |
| T42 | 166-176 | SP_7 | denotes | SARS-CoV-2 |
| T43 | 191-212 | GO:0001171 | denotes | reverse transcription |
| T44 | 266-274 | SP_7 | denotes | COVID-19 |
| T45 | 337-355 | CHEBI:5801;DG_20;CHEBI:5801 | denotes | hydroxychloroquine |
| T46 | 382-387 | UBERON:0001443 | denotes | chest |
| T47 | 446-451 | UBERON:0006518 | denotes | right |
| T48 | 452-457 | UBERON:0002168 | denotes | lower |
| T49 | 458-462 | UBERON:0002048 | denotes | lung |
| T50 | 464-473 | CHEBI:6426;DG_23;CHEBI:6426 | denotes | lopinavir |
| T51 | 474-483 | DG_30 | denotes | ritonavir |
| T52 | 706-711 | UBERON:0000004 | denotes | nasal |
| T53 | 729-740 | UBERON:0001004 | denotes | respiratory |
| T54 | 858-863 | UBERON:0000178 | denotes | blood |
| T55 | 876-881 | CL:0000738 | denotes | white |
| T56 | 882-887 | CL:0000738;UBERON:0000178 | denotes | blood |
| T57 | 888-892 | CL:0000738 | denotes | cell |
| T58 | 957-975 | PR:000005897 | denotes | C-reactive protein |
| T59 | 1088-1093 | UBERON:0000178;GO:0007596 | denotes | blood |
| T60 | 1094-1105 | GO:0007596 | denotes | coagulation |
| T61 | 1198-1211 | PR:000001393 | denotes | interleukin 6 |
| T62 | 1213-1217 | PR:000001393 | denotes | IL-6 |
| T63 | 1256-1265 | NCBITaxon:2 | denotes | bacterial |
| T64 | 1320-1331 | NCBITaxon:11886;UBERON:0001004 | denotes | respiratory |
| T65 | 1332-1339 | NCBITaxon:10239 | denotes | viruses |
| T66 | 1481-1490 | CHEBI:31781;DG_23;CHEBI:31781 | denotes | lopinavir |
| T67 | 1491-1500 | DG_30 | denotes | ritonavir |
| T68 | 1502-1520 | CHEBI:5801;DG_20;CHEBI:5801 | denotes | hydroxychloroquine |
| T69 | 1535-1546 | CHEBI:33282;CHEBI:33282 | denotes | antibiotics |
| T70 | 1609-1614 | UBERON:0001443 | denotes | chest |
| T71 | 1685-1689 | PR:000001393 | denotes | IL-6 |
| T72 | 1719-1733 | UBERON:0013755 | denotes | arterial blood |
| T73 | 1812-1830 | CHEBI:12071;DG_36;CHEBI:12071 | denotes | methylprednisolone |
| T74 | 1888-1894 | UBERON:0001969 | denotes | plasma |
| T75 | 1960-1968 | SP_7 | denotes | COVID-19 |
| T76 | 2002-2010 | SP_7 | denotes | COVID-19 |
| T77 | 2029-2034 | UBERON:0002048 | denotes | cough |
| T78 | 2127-2133 | UBERON:0001969 | denotes | plasma |
| T79 | 2159-2164 | UBERON:0000178 | denotes | blood |
| T80 | 2196-2202 | UBERON:0001969 | denotes | plasma |
| T81 | 2265-2270 | UBERON:0001638 | denotes | veins |
| T82 | 2348-2353 | UBERON:0000178 | denotes | Blood |
| T83 | 2579-2585 | UBERON:0001969 | denotes | plasma |
| T84 | 2606-2616 | SP_7 | denotes | SARS-CoV-2 |
| T85 | 2617-2629 | GO:0071743 | denotes | IgG antibody |
| T86 | 2633-2639 | UBERON:0001969 | denotes | plasma |
| T87 | 2705-2716 | NCBITaxon:11118 | denotes | Coronavirus |
| T88 | 2717-2725 | SP_7 | denotes | COVID-19 |
| T89 | 2726-2729 | GO:0071735 | denotes | IgG |
| T90 | 2741-2748 | BV_9 | denotes | Epitope |
| T91 | 2817-2820 | GO:0071735 | denotes | IgG |
| T92 | 2857-2863 | UBERON:0001969 | denotes | plasma |
| T93 | 3052-3058 | UBERON:0001969 | denotes | plasma |
| T94 | 3183-3187 | PR:000001393 | denotes | IL-6 |
| T95 | 3303-3308 | UBERON:0001443 | denotes | chest |
| T96 | 3351-3355 | UBERON:0002048 | denotes | lung |
| T97 | 3378-3388 | SP_7 | denotes | SARS-CoV-2 |
| T98 | 3453-3462 | SO:0000842 | denotes | region of |
| T99 | 3578-3584 | UBERON:0001969 | denotes | plasma |
| T100 | 3604-3614 | SP_7 | denotes | SARS-CoV-2 |
| T101 | 3666-3678 | UBERON:0003126 | denotes | tracheostomy |
| T102 | 3922-3931 | SO:0000842 | denotes | region of |
| T103 | 3950-3962 | SP_7 | denotes | severe acute |
| T104 | 3963-3974 | SP_7;UBERON:0001004 | denotes | respiratory |
| T105 | 3975-3997 | SP_7 | denotes | syndrome coronavirus-2 |
| T106 | 4001-4007 | UBERON:0007311 | denotes | sputum |
| T107 | 4021-4042 | GO:0001171 | denotes | reverse transcription |
| T108 | 4102-4120 | PR:000005897 | denotes | C-reactive protein |
| T109 | 4189-4195 | UBERON:0001969 | denotes | plasma |
| T110 | 4251-4257 | UBERON:0001969 | denotes | plasma |
| T21670 | 40-43 | NCBITaxon:9606 | denotes | man |
| T90604 | 166-176 | SP_7 | denotes | SARS-CoV-2 |
| T80731 | 191-212 | GO:0001171 | denotes | reverse transcription |
| T945 | 266-274 | SP_7 | denotes | COVID-19 |
| T75695 | 337-355 | CHEBI:5801;DG_20;CHEBI:5801 | denotes | hydroxychloroquine |
| T26119 | 382-387 | UBERON:0001443 | denotes | chest |
| T12811 | 446-451 | UBERON:0006518 | denotes | right |
| T39085 | 452-457 | UBERON:0002168 | denotes | lower |
| T88277 | 458-462 | UBERON:0002048 | denotes | lung |
| T67601 | 464-473 | CHEBI:6426;DG_23;CHEBI:6426 | denotes | lopinavir |
| T6063 | 474-483 | DG_30 | denotes | ritonavir |
| T3641 | 706-711 | UBERON:0000004 | denotes | nasal |
| T37550 | 729-740 | UBERON:0001004 | denotes | respiratory |
| T12571 | 858-863 | UBERON:0000178 | denotes | blood |
| T7691 | 876-881 | CL:0000738 | denotes | white |
| T67961 | 882-887 | CL:0000738;UBERON:0000178 | denotes | blood |
| T4078 | 888-892 | CL:0000738 | denotes | cell |
| T33243 | 957-975 | PR:000005897 | denotes | C-reactive protein |
| T35856 | 1088-1093 | UBERON:0000178;GO:0007596 | denotes | blood |
| T49965 | 1094-1105 | GO:0007596 | denotes | coagulation |
| T66699 | 1198-1211 | PR:000001393 | denotes | interleukin 6 |
| T70766 | 1213-1217 | PR:000001393 | denotes | IL-6 |
| T46580 | 1256-1265 | NCBITaxon:2 | denotes | bacterial |
| T23228 | 1320-1331 | NCBITaxon:11886;UBERON:0001004 | denotes | respiratory |
| T12091 | 1332-1339 | NCBITaxon:10239 | denotes | viruses |
| T32983 | 1481-1490 | CHEBI:31781;DG_23;CHEBI:31781 | denotes | lopinavir |
| T88600 | 1491-1500 | DG_30 | denotes | ritonavir |
| T34438 | 1502-1520 | CHEBI:5801;DG_20;CHEBI:5801 | denotes | hydroxychloroquine |
| T91254 | 1535-1546 | CHEBI:33282;CHEBI:33282 | denotes | antibiotics |
| T36244 | 1609-1614 | UBERON:0001443 | denotes | chest |
| T68247 | 1685-1689 | PR:000001393 | denotes | IL-6 |
| T14078 | 1719-1733 | UBERON:0013755 | denotes | arterial blood |
| T12001 | 1812-1830 | CHEBI:12071;DG_36;CHEBI:12071 | denotes | methylprednisolone |
| T69732 | 1888-1894 | UBERON:0001969 | denotes | plasma |
| T24933 | 1960-1968 | SP_7 | denotes | COVID-19 |
| T26519 | 2002-2010 | SP_7 | denotes | COVID-19 |
| T13155 | 2029-2034 | UBERON:0002048 | denotes | cough |
| T36018 | 2127-2133 | UBERON:0001969 | denotes | plasma |
| T98982 | 2159-2164 | UBERON:0000178 | denotes | blood |
| T46597 | 2196-2202 | UBERON:0001969 | denotes | plasma |
| T10409 | 2265-2270 | UBERON:0001638 | denotes | veins |
| T33070 | 2348-2353 | UBERON:0000178 | denotes | Blood |
| T18903 | 2579-2585 | UBERON:0001969 | denotes | plasma |
| T80173 | 2606-2616 | SP_7 | denotes | SARS-CoV-2 |
| T93751 | 2617-2629 | GO:0071743 | denotes | IgG antibody |
| T8558 | 2633-2639 | UBERON:0001969 | denotes | plasma |
| T31380 | 2705-2716 | NCBITaxon:11118 | denotes | Coronavirus |
| T2713 | 2717-2725 | SP_7 | denotes | COVID-19 |
| T11684 | 2726-2729 | GO:0071735 | denotes | IgG |
| T97911 | 2741-2748 | BV_9 | denotes | Epitope |
| T23659 | 2817-2820 | GO:0071735 | denotes | IgG |
| T34586 | 2857-2863 | UBERON:0001969 | denotes | plasma |
| T2920 | 3052-3058 | UBERON:0001969 | denotes | plasma |
| T21491 | 3183-3187 | PR:000001393 | denotes | IL-6 |
| T63448 | 3303-3308 | UBERON:0001443 | denotes | chest |
| T19167 | 3351-3355 | UBERON:0002048 | denotes | lung |
| T6202 | 3378-3388 | SP_7 | denotes | SARS-CoV-2 |
| T90488 | 3453-3462 | SO:0000842 | denotes | region of |
| T88565 | 3578-3584 | UBERON:0001969 | denotes | plasma |
| T26873 | 3604-3614 | SP_7 | denotes | SARS-CoV-2 |
| T29810 | 3666-3678 | UBERON:0003126 | denotes | tracheostomy |
| T12930 | 3922-3931 | SO:0000842 | denotes | region of |
| T73721 | 3950-3962 | SP_7 | denotes | severe acute |
| T62547 | 3963-3974 | SP_7;UBERON:0001004 | denotes | respiratory |
| T15734 | 3975-3997 | SP_7 | denotes | syndrome coronavirus-2 |
| T16790 | 4001-4007 | UBERON:0007311 | denotes | sputum |
| T55282 | 4021-4042 | GO:0001171 | denotes | reverse transcription |
| T83854 | 4102-4120 | PR:000005897 | denotes | C-reactive protein |
| T65566 | 4189-4195 | UBERON:0001969 | denotes | plasma |
| T86318 | 4251-4257 | UBERON:0001969 | denotes | plasma |