PMC:7152526 / 11-797 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7152526","sourcedb":"PMC","sourceid":"7152526","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7152526","text":"alescent Plasma Therapy in Two COVID-19 Patients with Acute Respiratory Distress Syndrome in Korea\n\nAbstract\nCoronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 not yet has established its treatment, but convalescent plasma has been expected to increase survival rates as in the case with other emerging viral infections. We describe two cases of COVID-19 treated with convalescent plasma infusion. Both patients presented severe pneumonia with acute respiratory distress syndrome and showed a favorable outcome after the use of convalescent plasma in addition to systemic corticosteroid. To our knowledge, this is the first report of the use of convalescent plasma therapy for COVID-19 in Korea.\n\nGraphical Abstract\n\nINTRODUCTION\nAn outbreak o","divisions":[{"label":"abstract","span":{"begin":109,"end":738}},{"label":"p","span":{"begin":109,"end":738}},{"label":"abstract","span":{"begin":740,"end":758}},{"label":"title","span":{"begin":740,"end":758}},{"label":"title","span":{"begin":760,"end":772}}],"tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"3","span":{"begin":40,"end":48},"obj":"Species"},{"id":"4","span":{"begin":31,"end":39},"obj":"Disease"},{"id":"5","span":{"begin":54,"end":89},"obj":"Disease"},{"id":"15","span":{"begin":155,"end":202},"obj":"Species"},{"id":"16","span":{"begin":446,"end":454},"obj":"Species"},{"id":"17","span":{"begin":109,"end":133},"obj":"Disease"},{"id":"18","span":{"begin":135,"end":143},"obj":"Disease"},{"id":"19","span":{"begin":346,"end":362},"obj":"Disease"},{"id":"20","span":{"begin":389,"end":397},"obj":"Disease"},{"id":"21","span":{"begin":472,"end":481},"obj":"Disease"},{"id":"22","span":{"begin":487,"end":522},"obj":"Disease"},{"id":"23","span":{"begin":720,"end":728},"obj":"Disease"}],"attributes":[{"id":"A3","pred":"tao:has_database_id","subj":"3","obj":"Tax:9606"},{"id":"A4","pred":"tao:has_database_id","subj":"4","obj":"MESH:C000657245"},{"id":"A5","pred":"tao:has_database_id","subj":"5","obj":"MESH:D012128"},{"id":"A15","pred":"tao:has_database_id","subj":"15","obj":"Tax:2697049"},{"id":"A16","pred":"tao:has_database_id","subj":"16","obj":"Tax:9606"},{"id":"A17","pred":"tao:has_database_id","subj":"17","obj":"MESH:C000657245"},{"id":"A18","pred":"tao:has_database_id","subj":"18","obj":"MESH:C000657245"},{"id":"A19","pred":"tao:has_database_id","subj":"19","obj":"MESH:D001102"},{"id":"A20","pred":"tao:has_database_id","subj":"20","obj":"MESH:C000657245"},{"id":"A21","pred":"tao:has_database_id","subj":"21","obj":"MESH:D011014"},{"id":"A22","pred":"tao:has_database_id","subj":"22","obj":"MESH:D012128"},{"id":"A23","pred":"tao:has_database_id","subj":"23","obj":"MESH:C000657245"},{"subj":"3","pred":"source","obj":"LitCovid-PubTator"},{"subj":"4","pred":"source","obj":"LitCovid-PubTator"},{"subj":"5","pred":"source","obj":"LitCovid-PubTator"},{"subj":"15","pred":"source","obj":"LitCovid-PubTator"},{"subj":"16","pred":"source","obj":"LitCovid-PubTator"},{"subj":"17","pred":"source","obj":"LitCovid-PubTator"},{"subj":"18","pred":"source","obj":"LitCovid-PubTator"},{"subj":"19","pred":"source","obj":"LitCovid-PubTator"},{"subj":"20","pred":"source","obj":"LitCovid-PubTator"},{"subj":"21","pred":"source","obj":"LitCovid-PubTator"},{"subj":"22","pred":"source","obj":"LitCovid-PubTator"},{"subj":"23","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":9,"end":15},"obj":"Body_part"},{"id":"T2","span":{"begin":259,"end":265},"obj":"Body_part"},{"id":"T3","span":{"begin":424,"end":430},"obj":"Body_part"},{"id":"T4","span":{"begin":584,"end":590},"obj":"Body_part"},{"id":"T5","span":{"begin":701,"end":707},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma62970"},{"subj":"T1","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T2","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T3","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T5","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T1","span":{"begin":31,"end":39},"obj":"Disease"},{"id":"T2","span":{"begin":54,"end":89},"obj":"Disease"},{"id":"T3","span":{"begin":60,"end":89},"obj":"Disease"},{"id":"T4","span":{"begin":109,"end":133},"obj":"Disease"},{"id":"T5","span":{"begin":135,"end":143},"obj":"Disease"},{"id":"T6","span":{"begin":155,"end":202},"obj":"Disease"},{"id":"T7","span":{"begin":155,"end":188},"obj":"Disease"},{"id":"T8","span":{"begin":346,"end":362},"obj":"Disease"},{"id":"T9","span":{"begin":389,"end":397},"obj":"Disease"},{"id":"T10","span":{"begin":472,"end":481},"obj":"Disease"},{"id":"T11","span":{"begin":487,"end":522},"obj":"Disease"},{"id":"T12","span":{"begin":493,"end":522},"obj":"Disease"},{"id":"T13","span":{"begin":720,"end":728},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0009971"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A6","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A12","pred":"mondo_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/MONDO_0009971"},{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"subj":"T1","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T2","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T3","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T5","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T6","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T7","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T8","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T9","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T10","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T11","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T12","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T13","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T1","span":{"begin":9,"end":15},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T2","span":{"begin":211,"end":214},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T3","span":{"begin":259,"end":265},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T4","span":{"begin":266,"end":269},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T5","span":{"begin":424,"end":430},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T6","span":{"begin":534,"end":535},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T7","span":{"begin":584,"end":590},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T8","span":{"begin":701,"end":707},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T2","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T3","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T5","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T6","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T7","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T8","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1","span":{"begin":615,"end":629},"obj":"Chemical"}],"attributes":[{"id":"A1","pred":"chebi_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_50858"},{"subj":"T1","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":346,"end":362},"obj":"http://purl.obolibrary.org/obo/GO_0016032"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T2","span":{"begin":100,"end":108},"obj":"Sentence"},{"id":"T3","span":{"begin":109,"end":363},"obj":"Sentence"},{"id":"T4","span":{"begin":364,"end":440},"obj":"Sentence"},{"id":"T5","span":{"begin":441,"end":630},"obj":"Sentence"},{"id":"T6","span":{"begin":631,"end":738},"obj":"Sentence"},{"id":"T7","span":{"begin":740,"end":758},"obj":"Sentence"},{"id":"T8","span":{"begin":760,"end":772},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T2","pred":"source","obj":"LitCovid-sentences"},{"subj":"T3","pred":"source","obj":"LitCovid-sentences"},{"subj":"T4","pred":"source","obj":"LitCovid-sentences"},{"subj":"T5","pred":"source","obj":"LitCovid-sentences"},{"subj":"T6","pred":"source","obj":"LitCovid-sentences"},{"subj":"T7","pred":"source","obj":"LitCovid-sentences"},{"subj":"T8","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T1","span":{"begin":60,"end":80},"obj":"Phenotype"},{"id":"T2","span":{"begin":472,"end":481},"obj":"Phenotype"},{"id":"T3","span":{"begin":493,"end":513},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/HP_0002098"},{"id":"A2","pred":"hp_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0002098"},{"subj":"T1","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T2","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T3","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T1","span":{"begin":9,"end":15},"obj":"UBERON:0001969"},{"id":"T2","span":{"begin":31,"end":39},"obj":"SP_7"},{"id":"T3","span":{"begin":109,"end":120},"obj":"NCBITaxon:11118"},{"id":"T4","span":{"begin":135,"end":143},"obj":"SP_7"},{"id":"T5","span":{"begin":155,"end":167},"obj":"SP_7"},{"id":"T6","span":{"begin":168,"end":179},"obj":"SP_7;UBERON:0001004"},{"id":"T7","span":{"begin":180,"end":202},"obj":"SP_7"},{"id":"T8","span":{"begin":259,"end":265},"obj":"UBERON:0001969"},{"id":"T9","span":{"begin":346,"end":351},"obj":"NCBITaxon:10239"},{"id":"T10","span":{"begin":389,"end":397},"obj":"SP_7"},{"id":"T11","span":{"begin":424,"end":430},"obj":"UBERON:0001969"},{"id":"T12","span":{"begin":493,"end":504},"obj":"UBERON:0001004"},{"id":"T13","span":{"begin":584,"end":590},"obj":"UBERON:0001969"},{"id":"T14","span":{"begin":615,"end":629},"obj":"CHEBI:50858;CHEBI:50858"},{"id":"T15","span":{"begin":701,"end":707},"obj":"UBERON:0001969"},{"id":"T16","span":{"begin":720,"end":728},"obj":"SP_7"},{"id":"T96845","span":{"begin":9,"end":15},"obj":"UBERON:0001969"},{"id":"T86945","span":{"begin":31,"end":39},"obj":"SP_7"},{"id":"T9965","span":{"begin":109,"end":120},"obj":"NCBITaxon:11118"},{"id":"T84612","span":{"begin":135,"end":143},"obj":"SP_7"},{"id":"T53837","span":{"begin":155,"end":167},"obj":"SP_7"},{"id":"T52665","span":{"begin":168,"end":179},"obj":"SP_7;UBERON:0001004"},{"id":"T91803","span":{"begin":180,"end":202},"obj":"SP_7"},{"id":"T71695","span":{"begin":259,"end":265},"obj":"UBERON:0001969"},{"id":"T89918","span":{"begin":346,"end":351},"obj":"NCBITaxon:10239"},{"id":"T68910","span":{"begin":389,"end":397},"obj":"SP_7"},{"id":"T66646","span":{"begin":424,"end":430},"obj":"UBERON:0001969"},{"id":"T33202","span":{"begin":493,"end":504},"obj":"UBERON:0001004"},{"id":"T85214","span":{"begin":584,"end":590},"obj":"UBERON:0001969"},{"id":"T61698","span":{"begin":615,"end":629},"obj":"CHEBI:50858;CHEBI:50858"},{"id":"T26474","span":{"begin":701,"end":707},"obj":"UBERON:0001969"},{"id":"T87558","span":{"begin":720,"end":728},"obj":"SP_7"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T2","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T3","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T4","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T5","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T6","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T7","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T8","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T9","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T10","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T11","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T12","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T13","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T14","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T15","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T16","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T96845","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T86945","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T9965","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T84612","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T53837","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T52665","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T91803","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T71695","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T89918","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T68910","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T66646","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T33202","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T85214","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T61698","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T26474","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T87558","pred":"source","obj":"LitCovid-PMC-OGER-BB"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#ec93bf","default":true},{"id":"LitCovid-PD-FMA-UBERON","color":"#93d9ec"},{"id":"LitCovid-PD-MONDO","color":"#ece593"},{"id":"LitCovid-PD-CLO","color":"#cb93ec"},{"id":"LitCovid-PD-CHEBI","color":"#93ecb1"},{"id":"LitCovid-PD-GO-BP","color":"#ec9793"},{"id":"LitCovid-sentences","color":"#93a9ec"},{"id":"LitCovid-PD-HP","color":"#c3ec93"},{"id":"LitCovid-PMC-OGER-BB","color":"#ec93dd"}]}]}}