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PMC:7148425 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1 17-27 Species denotes SARS-CoV-2 Tax:2697049
10 102-112 Species denotes SARS-CoV-2 Tax:2697049
11 207-213 Species denotes people Tax:9606
12 288-294 Species denotes people Tax:9606
13 547-553 Species denotes people Tax:9606
14 659-669 Species denotes SARS-CoV-2 Tax:2697049
15 329-338 Disease denotes infection MESH:D007239
16 850-855 Disease denotes COVID MESH:C000657245
17 866-886 Disease denotes SARS-CoV-2 infection MESH:C000657245
28 985-996 Species denotes Coronavirus Tax:694448
29 997-1007 Species denotes SARS-CoV-2 Tax:2697049
30 1225-1233 Species denotes children Tax:9606
31 1294-1300 Species denotes people Tax:9606
32 1566-1574 Species denotes patients Tax:9606
33 2227-2237 Species denotes SARS-CoV-2 Tax:2697049
34 1407-1415 Disease denotes covid-19 MESH:C000657245
35 1423-1431 Disease denotes covid-19 MESH:C000657245
36 1710-1729 Disease denotes Coronavirus disease MESH:D018352
37 1731-1736 Disease denotes COVID MESH:C000657245
39 2531-2552 Disease denotes COVID immunopathology MESH:C000657245
52 2766-2776 Species denotes SARS-CoV-2 Tax:2697049
53 2848-2854 Species denotes people Tax:9606
54 4040-4050 Species denotes SARS-CoV-2 Tax:2697049
55 4787-4794 Species denotes patient Tax:9606
56 4893-4899 Species denotes people Tax:9606
57 3119-3152 Disease denotes Severe acute respiratory syndrome MESH:D045169
58 3249-3255 Disease denotes sepsis MESH:D018805
59 3395-3417 Disease denotes multiple organ failure MESH:D009102
60 3522-3531 Disease denotes infection MESH:D007239
61 3582-3598 Disease denotes memory cytotoxic MESH:D064420
62 3924-3933 Disease denotes infection MESH:D007239
63 4555-4561 Disease denotes cancer MESH:D009369
71 6413-6419 Species denotes people Tax:9606
72 5202-5215 Disease denotes lymphopoiesis
73 5668-5677 Disease denotes infection MESH:D007239
74 6268-6277 Disease denotes infection MESH:D007239
75 6847-6858 Disease denotes detrimental MESH:D008569
76 6874-6894 Disease denotes SARS-CoV-2 infection MESH:C000657245
77 6988-6997 Disease denotes infection MESH:D007239
87 7502-7505 Gene denotes CD4 Gene:920
88 7184-7192 Species denotes SARS-CoV Tax:694009
89 7360-7366 Species denotes humans Tax:9606
90 7829-7833 Species denotes H7N1 Tax:119216
91 8021-8031 Species denotes SARS-CoV-2 Tax:2697049
92 8231-8241 Species denotes SARS-CoV-2 Tax:2697049
93 7217-7226 Disease denotes infection MESH:D007239
94 7386-7391 Disease denotes Fever MESH:D005334
95 8092-8112 Disease denotes SARS-CoV-1 infection MESH:C000657245
97 8654-8659 Disease denotes COVID MESH:C000657245
106 10060-10066 Species denotes people Tax:9606
107 8806-8811 Disease denotes COVID MESH:C000657245
108 8982-8991 Disease denotes infection MESH:D007239
109 9120-9129 Disease denotes infection MESH:D007239
110 9428-9437 Disease denotes infection MESH:D007239
111 9523-9536 Disease denotes hematopoiesis MESH:C536227
112 9578-9599 Disease denotes dysfunctional myeloid MESH:D007951
113 9811-9823 Disease denotes inflammation MESH:D007249
116 10725-10735 Species denotes SARS-CoV-2 Tax:2697049
117 10758-10763 Disease denotes COVID MESH:C000657245

2_test

Id Subject Object Predicate Lexical cue
32300370-32113509-46535320 1999-2000 32113509 denotes 1
32300370-32179860-46535321 2323-2324 32179860 denotes 2
32300370-26867174-46535322 2989-2990 26867174 denotes 4
32300370-28466096-46535323 3279-3280 28466096 denotes 5
32300370-31528180-46535324 5024-5025 31528180 denotes 6
32300370-26459351-46535325 7585-7586 26459351 denotes 7
32300370-24642138-46535326 8138-8139 24642138 denotes 8
T12898 1999-2000 32113509 denotes 1
T57836 2323-2324 32179860 denotes 2
T43198 2989-2990 26867174 denotes 4
T956 3279-3280 28466096 denotes 5
T20747 5024-5025 31528180 denotes 6
T83295 7585-7586 26459351 denotes 7
T89624 8138-8139 24642138 denotes 8

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T1 17-27 SP_7 denotes SARS-CoV-2
T2 102-112 SP_7 denotes SARS-CoV-2
T3 207-213 NCBITaxon:9606 denotes people
T4 225-231 UBERON:0000467 denotes health
T5 288-294 NCBITaxon:9606 denotes people
T6 346-352 UBERON:0007023 denotes adults
T7 379-383 UBERON:0000104 denotes life
T8 396-407 UBERON:0001004 denotes respiratory
T9 547-553 NCBITaxon:9606 denotes people
T10 634-640 GO:0007568 denotes ageing
T11 659-669 SP_7 denotes SARS-CoV-2
T12 830-836 UBERON:0002405;GO:0006955 denotes immune
T13 837-846 GO:0006955 denotes responses
T14 866-876 SP_7 denotes SARS-CoV-2
T15 945-951 UBERON:0007023 denotes adults
T16 985-996 NCBITaxon:11118 denotes Coronavirus
T17 997-1007 SP_7 denotes SARS-CoV-2
T18 1262-1268 UBERON:0007023 denotes adults
T19 1294-1300 NCBITaxon:9606 denotes people
T20 1407-1415 SP_7 denotes covid-19
T21 1423-1431 SP_7 denotes covid-19
T22 1710-1721 NCBITaxon:11118 denotes Coronavirus
T23 1926-1931 CHEBI:23888;CHEBI:23888 denotes drugs
T24 1940-1946 NCBITaxon:10239 denotes virals
T25 2227-2237 SP_7 denotes SARS-CoV-2
T26 2368-2374 UBERON:0002405 denotes immune
T27 2620-2625 NCBITaxon:10239 denotes virus
T28 2691-2696 NCBITaxon:10239 denotes viral
T29 2697-2704 CHEBI:59132;CHEBI:59132 denotes antigen
T30 2766-2776 SP_7 denotes SARS-CoV-2
T31 2848-2854 NCBITaxon:9606 denotes people
T32 2860-2865 NCBITaxon:10239 denotes virus
T33 2886-2896 GO:0030260 denotes entry into
T34 2927-2940 GO:0005622 denotes intracellular
T35 2963-2968 NCBITaxon:10239 denotes viral
T36 2969-2976 GO:0006952 denotes defence
T37 3008-3018 GO:0008219 denotes cell death
T38 3046-3055 CHEBI:36357;CHEBI:36357 denotes molecules
T39 3057-3062 CHEBI:51231;CHEBI:51231 denotes DAMPs
T40 3068-3073 NCBITaxon:10239 denotes viral
T41 3132-3143 UBERON:0001004 denotes respiratory
T42 3166-3178 GO:0065007 denotes dysregulated
T43 3318-3323 NCBITaxon:10239 denotes virus
T44 3354-3360 UBERON:0000062 denotes organs
T45 3375-3379 UBERON:0002048 denotes lung
T46 3404-3409 UBERON:0000062 denotes organ
T47 3502-3510 GO:0042571 denotes antibody
T48 3558-3563 NCBITaxon:10239 denotes virus
T49 3582-3588 GO:0007613 denotes memory
T50 3589-3606 CL:0000910 denotes cytotoxic T cells
T51 3614-3618 UBERON:0002048 denotes lung
T52 3630-3635 NCBITaxon:10239;GO:0006260 denotes viral
T53 3636-3647 GO:0006260 denotes replication
T54 3705-3712 CHEBI:59132;CHEBI:59132 denotes antigen
T55 3731-3738 CL:0000084 denotes T cells
T56 3743-3750 CL:0000236 denotes B cells
T57 3800-3810 UBERON:0000029 denotes lymph node
T58 3904-3912 GO:0042571 denotes antibody
T59 4040-4050 SP_7 denotes SARS-CoV-2
T60 4084-4088 UBERON:0002048 denotes lung
T61 4160-4168 GO:0042571 denotes antibody
T62 4271-4277 UBERON:0002405 denotes immune
T63 4539-4547 GO:0042571 denotes antibody
T64 4684-4692 GO:0042571 denotes antibody
T65 4893-4899 NCBITaxon:9606 denotes people
T66 4957-4963 UBERON:0002405 denotes immune
T67 5079-5092 UBERON:0002405 denotes immune system
T68 5139-5145 UBERON:0002405;GO:0006955;CL:0000738 denotes immune
T69 5146-5150 CL:0000738;GO:0070285 denotes cell
T70 5151-5161 GO:0016064 denotes production
T71 5169-5180 UBERON:0002371 denotes bone marrow
T72 5202-5215 GO:0019835 denotes lymphopoiesis
T73 5240-5247 CL:0000763 denotes myeloid
T74 5303-5309 UBERON:0002370 denotes Thymic
T75 5363-5370 CL:0000084 denotes T cells
T76 5432-5443 CL:0000080 denotes circulating
T77 5450-5457 CL:0000236 denotes B cells
T78 5486-5493 CL:0000084 denotes T cells
T79 5575-5580 GO:0007568 denotes aging
T80 5626-5632 UBERON:0002405;CL:0000738 denotes immune
T81 5633-5638 CL:0000738 denotes cells
T82 5644-5655 CL:0000775 denotes neutrophils
T83 5730-5743 UBERON:0002405 denotes immune system
T84 5819-5827 GO:0002250 denotes adaptive
T85 5828-5834 GO:0002250;UBERON:0002405 denotes immune
T86 5835-5844 GO:0002250 denotes responses
T87 5878-5885 CHEBI:59132;CHEBI:59132 denotes antigen
T88 5933-5943 UBERON:0000029 denotes lymph node
T89 6006-6013 GO:0065007 denotes control
T90 6106-6114 GO:0002250 denotes adaptive
T91 6115-6121 GO:0002250;UBERON:0002405 denotes immune
T92 6122-6130 GO:0002250 denotes response
T93 6191-6199 CHEBI:35224;CHEBI:35224 denotes effector
T94 6200-6207 CL:0000911 denotes T cells
T95 6212-6219 CL:0000236 denotes B cells
T96 6335-6341 UBERON:0007023 denotes adults
T97 6389-6399 NCBITaxon:1 denotes individual
T98 6413-6419 NCBITaxon:9606 denotes people
T99 6598-6604 UBERON:0002405 denotes immune
T100 6636-6646 NCBITaxon:1 denotes individual
T101 6724-6735 GO:0000075 denotes checkpoints
T102 6784-6790 UBERON:0002405 denotes immune
T103 6874-6884 SP_7 denotes SARS-CoV-2
T104 7184-7192 SP_10 denotes SARS-CoV
T105 7311-7317 UBERON:0002405 denotes immune
T106 7348-7356 CHEBI:59132;CHEBI:59132 denotes antigens
T107 7360-7366 NCBITaxon:9606 denotes humans
T108 7444-7451 CHEBI:59132;CHEBI:59132 denotes antigen
T109 7485-7492 CHEBI:59132;CHEBI:59132 denotes antigen
T110 7502-7505 PR:000001004 denotes CD4
T111 7546-7554 GO:0042571;GO:0016064 denotes antibody
T112 7555-7564 GO:0016064 denotes responses
T113 7823-7828 NCBITaxon:8782 denotes avian
T114 7944-7949 NCBITaxon:10239 denotes virus
T115 8000-8006 UBERON:0007023 denotes adults
T116 8021-8031 SP_7 denotes SARS-CoV-2
T117 8033-8040 NCBITaxon:9443 denotes Primate
T118 8081-8088 NCBITaxon:9527 denotes monkeys
T119 8092-8100 SP_10 denotes SARS-CoV
T120 8211-8218 CHEBI:59132;CHEBI:59132 denotes antigen
T121 8219-8227 BV_9 denotes epitopes
T122 8231-8241 SP_7 denotes SARS-CoV-2
T123 8251-8259 GO:0042571 denotes antibody
T124 8260-8266 CL:0000236 denotes B cell
T125 8281-8287 CL:0000084 denotes T cell
T126 8405-8419 BV_26 denotes vaccine design
T127 8434-8439 UBERON:0007023 denotes adult
T128 8472-8473 CL:0000084;GO:0042110 denotes T
T129 8478-8484 CL:0000236 denotes B cell
T130 8525-8531 UBERON:0002405 denotes immune
T131 8762-8767 UBERON:0007023 denotes adult
T132 8834-8840 UBERON:0007023 denotes adults
T133 9090-9105 CHEBI:52217;CHEBI:52217 denotes Pharmacological
T134 9196-9201 NCBITaxon:10239 denotes viral
T135 9225-9234 CHEBI:36357;CHEBI:36357 denotes molecules
T136 9315-9321 UBERON:0002405 denotes immune
T137 9409-9415 UBERON:0002405;GO:0006955 denotes immune
T138 9416-9424 GO:0006955 denotes response
T139 9523-9536 GO:0030097 denotes hematopoiesis
T140 9592-9605 CL:0000763 denotes myeloid cells
T141 9658-9662 UBERON:0002048 denotes lung
T142 9681-9687 CL:0000084 denotes T cell
T143 9732-9738 UBERON:0002370 denotes thymus
T144 9764-9771 CL:0000084 denotes T cells
T145 9784-9794 GO:0065007;CL:0000815 denotes regulatory
T146 9795-9802 CL:0000815 denotes T cells
T147 9827-9832 GO:0000075 denotes check
T148 9852-9859 CHEBI:59132;CHEBI:59132 denotes antigen
T149 9889-9900 UBERON:0000029 denotes lymph nodes
T150 9921-9922 CL:0000236 denotes T
T151 9923-9929 CL:0000236 denotes B cell
T152 10060-10066 NCBITaxon:9606 denotes people
T153 10161-10168 NCBITaxon:10239 denotes viruses
T154 10190-10195 NCBITaxon:10239 denotes virus
T155 10435-10440 NCBITaxon:10239 denotes virus
T156 10483-10489 UBERON:0002405 denotes immune
T157 10490-10496 GO:0007613 denotes memory
T158 10708-10714 UBERON:0002405;GO:0045087 denotes immune
T159 10715-10724 GO:0045087 denotes responses
T160 10725-10735 SP_7 denotes SARS-CoV-2
T161 10822-10828 UBERON:0007023 denotes adults
T3867 17-27 SP_7 denotes SARS-CoV-2
T25516 102-112 SP_7 denotes SARS-CoV-2
T48981 207-213 NCBITaxon:9606 denotes people
T15749 225-231 UBERON:0000467 denotes health
T86841 288-294 NCBITaxon:9606 denotes people
T87355 346-352 UBERON:0007023 denotes adults
T24812 379-383 UBERON:0000104 denotes life
T41576 396-407 UBERON:0001004 denotes respiratory
T90405 547-553 NCBITaxon:9606 denotes people
T79061 634-640 GO:0007568 denotes ageing
T6587 659-669 SP_7 denotes SARS-CoV-2
T8998 830-836 UBERON:0002405;GO:0006955 denotes immune
T16575 837-846 GO:0006955 denotes responses
T55569 866-876 SP_7 denotes SARS-CoV-2
T65586 945-951 UBERON:0007023 denotes adults
T86919 985-996 NCBITaxon:11118 denotes Coronavirus
T90060 997-1007 SP_7 denotes SARS-CoV-2
T8914 1262-1268 UBERON:0007023 denotes adults
T83858 1294-1300 NCBITaxon:9606 denotes people
T77217 1407-1415 SP_7 denotes covid-19
T13263 1423-1431 SP_7 denotes covid-19
T60504 1710-1721 NCBITaxon:11118 denotes Coronavirus
T57286 1926-1931 CHEBI:23888;CHEBI:23888 denotes drugs
T55368 1940-1946 NCBITaxon:10239 denotes virals
T67444 2227-2237 SP_7 denotes SARS-CoV-2
T25281 2368-2374 UBERON:0002405 denotes immune
T54101 2620-2625 NCBITaxon:10239 denotes virus
T44031 2691-2696 NCBITaxon:10239 denotes viral
T4383 2697-2704 CHEBI:59132;CHEBI:59132 denotes antigen
T81980 2766-2776 SP_7 denotes SARS-CoV-2
T36640 2848-2854 NCBITaxon:9606 denotes people
T54613 2860-2865 NCBITaxon:10239 denotes virus
T27613 2886-2896 GO:0030260 denotes entry into
T44981 2927-2940 GO:0005622 denotes intracellular
T88515 2963-2968 NCBITaxon:10239 denotes viral
T84065 2969-2976 GO:0006952 denotes defence
T25786 3008-3018 GO:0008219 denotes cell death
T8397 3046-3055 CHEBI:36357;CHEBI:36357 denotes molecules
T93139 3057-3062 CHEBI:51231;CHEBI:51231 denotes DAMPs
T92507 3068-3073 NCBITaxon:10239 denotes viral
T30873 3132-3143 UBERON:0001004 denotes respiratory
T73756 3166-3178 GO:0065007 denotes dysregulated
T7606 3318-3323 NCBITaxon:10239 denotes virus
T39976 3354-3360 UBERON:0000062 denotes organs
T67744 3375-3379 UBERON:0002048 denotes lung
T16617 3404-3409 UBERON:0000062 denotes organ
T78881 3502-3510 GO:0042571 denotes antibody
T73044 3558-3563 NCBITaxon:10239 denotes virus
T32557 3582-3588 GO:0007613 denotes memory
T56653 3589-3606 CL:0000910 denotes cytotoxic T cells
T52969 3614-3618 UBERON:0002048 denotes lung
T98279 3630-3635 NCBITaxon:10239;GO:0006260 denotes viral
T86489 3636-3647 GO:0006260 denotes replication
T90345 3705-3712 CHEBI:59132;CHEBI:59132 denotes antigen
T93898 3731-3738 CL:0000084 denotes T cells
T24586 3743-3750 CL:0000236 denotes B cells
T71351 3800-3810 UBERON:0000029 denotes lymph node
T89054 3904-3912 GO:0042571 denotes antibody
T21969 4040-4050 SP_7 denotes SARS-CoV-2
T60923 4084-4088 UBERON:0002048 denotes lung
T37411 4160-4168 GO:0042571 denotes antibody
T82134 4271-4277 UBERON:0002405 denotes immune
T5328 4539-4547 GO:0042571 denotes antibody
T1265 4684-4692 GO:0042571 denotes antibody
T87826 4893-4899 NCBITaxon:9606 denotes people
T74120 4957-4963 UBERON:0002405 denotes immune
T50706 5079-5092 UBERON:0002405 denotes immune system
T63255 5139-5145 UBERON:0002405;GO:0006955;CL:0000738 denotes immune
T92543 5146-5150 CL:0000738;GO:0070285 denotes cell
T80900 5151-5161 GO:0016064 denotes production
T49243 5169-5180 UBERON:0002371 denotes bone marrow
T20340 5202-5215 GO:0019835 denotes lymphopoiesis
T58375 5240-5247 CL:0000763 denotes myeloid
T52332 5303-5309 UBERON:0002370 denotes Thymic
T92765 5363-5370 CL:0000084 denotes T cells
T36406 5432-5443 CL:0000080 denotes circulating
T46772 5450-5457 CL:0000236 denotes B cells
T63184 5486-5493 CL:0000084 denotes T cells
T55334 5575-5580 GO:0007568 denotes aging
T64610 5626-5632 UBERON:0002405;CL:0000738 denotes immune
T19866 5633-5638 CL:0000738 denotes cells
T84536 5644-5655 CL:0000775 denotes neutrophils
T6164 5730-5743 UBERON:0002405 denotes immune system
T80860 5819-5827 GO:0002250 denotes adaptive
T77233 5828-5834 GO:0002250;UBERON:0002405 denotes immune
T97927 5835-5844 GO:0002250 denotes responses
T29382 5878-5885 CHEBI:59132;CHEBI:59132 denotes antigen
T56898 5933-5943 UBERON:0000029 denotes lymph node
T51529 6006-6013 GO:0065007 denotes control
T1622 6106-6114 GO:0002250 denotes adaptive
T73017 6115-6121 GO:0002250;UBERON:0002405 denotes immune
T10815 6122-6130 GO:0002250 denotes response
T75965 6191-6199 CHEBI:35224;CHEBI:35224 denotes effector
T21829 6200-6207 CL:0000911 denotes T cells
T28203 6212-6219 CL:0000236 denotes B cells
T27153 6335-6341 UBERON:0007023 denotes adults
T25164 6389-6399 NCBITaxon:1 denotes individual
T77782 6413-6419 NCBITaxon:9606 denotes people
T97146 6598-6604 UBERON:0002405 denotes immune
T68314 6636-6646 NCBITaxon:1 denotes individual
T95197 6724-6735 GO:0000075 denotes checkpoints
T18482 6784-6790 UBERON:0002405 denotes immune
T9428 6874-6884 SP_7 denotes SARS-CoV-2
T75384 7184-7192 SP_10 denotes SARS-CoV
T50695 7311-7317 UBERON:0002405 denotes immune
T94168 7348-7356 CHEBI:59132;CHEBI:59132 denotes antigens
T28705 7360-7366 NCBITaxon:9606 denotes humans
T64389 7444-7451 CHEBI:59132;CHEBI:59132 denotes antigen
T38276 7485-7492 CHEBI:59132;CHEBI:59132 denotes antigen
T7547 7502-7505 PR:000001004 denotes CD4
T95385 7546-7554 GO:0042571;GO:0016064 denotes antibody
T9300 7555-7564 GO:0016064 denotes responses
T3690 7823-7828 NCBITaxon:8782 denotes avian
T99926 7944-7949 NCBITaxon:10239 denotes virus
T69227 8000-8006 UBERON:0007023 denotes adults
T14255 8021-8031 SP_7 denotes SARS-CoV-2
T82466 8033-8040 NCBITaxon:9443 denotes Primate
T65870 8081-8088 NCBITaxon:9527 denotes monkeys
T94402 8092-8100 SP_10 denotes SARS-CoV
T30255 8211-8218 CHEBI:59132;CHEBI:59132 denotes antigen
T66613 8219-8227 BV_9 denotes epitopes
T56090 8231-8241 SP_7 denotes SARS-CoV-2
T36704 8251-8259 GO:0042571 denotes antibody
T7050 8260-8266 CL:0000236 denotes B cell
T65037 8281-8287 CL:0000084 denotes T cell
T67706 8405-8419 BV_26 denotes vaccine design
T19395 8434-8439 UBERON:0007023 denotes adult
T25144 8472-8473 CL:0000084;GO:0042110 denotes T
T99685 8478-8484 CL:0000236 denotes B cell
T30945 8525-8531 UBERON:0002405 denotes immune
T88471 8762-8767 UBERON:0007023 denotes adult
T69140 8834-8840 UBERON:0007023 denotes adults
T99077 9090-9105 CHEBI:52217;CHEBI:52217 denotes Pharmacological
T52993 9196-9201 NCBITaxon:10239 denotes viral
T19904 9225-9234 CHEBI:36357;CHEBI:36357 denotes molecules
T34929 9315-9321 UBERON:0002405 denotes immune
T29544 9409-9415 UBERON:0002405;GO:0006955 denotes immune
T87061 9416-9424 GO:0006955 denotes response
T80178 9523-9536 GO:0030097 denotes hematopoiesis
T98847 9592-9605 CL:0000763 denotes myeloid cells
T51000 9658-9662 UBERON:0002048 denotes lung
T67065 9681-9687 CL:0000084 denotes T cell
T21403 9732-9738 UBERON:0002370 denotes thymus
T1426 9764-9771 CL:0000084 denotes T cells
T78479 9784-9794 GO:0065007;CL:0000815 denotes regulatory
T29874 9795-9802 CL:0000815 denotes T cells
T64682 9827-9832 GO:0000075 denotes check
T64287 9852-9859 CHEBI:59132;CHEBI:59132 denotes antigen
T40891 9889-9900 UBERON:0000029 denotes lymph nodes
T27403 9921-9922 CL:0000236 denotes T
T51932 9923-9929 CL:0000236 denotes B cell
T33921 10060-10066 NCBITaxon:9606 denotes people
T83204 10161-10168 NCBITaxon:10239 denotes viruses
T59755 10190-10195 NCBITaxon:10239 denotes virus
T59738 10435-10440 NCBITaxon:10239 denotes virus
T76554 10483-10489 UBERON:0002405 denotes immune
T1318 10490-10496 GO:0007613 denotes memory
T29495 10708-10714 UBERON:0002405;GO:0045087 denotes immune
T41257 10715-10724 GO:0045087 denotes responses
T44798 10725-10735 SP_7 denotes SARS-CoV-2
T54015 10822-10828 UBERON:0007023 denotes adults

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 396-420 Body_part denotes respiratory and systemic http://purl.org/sig/ont/fma/fma7158
T2 2902-2907 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T3 2942-2946 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T4 3008-3012 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T5 3262-3270 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T6 3375-3379 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T7 3404-3409 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T8 3502-3510 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T9 3589-3606 Body_part denotes cytotoxic T cells http://purl.org/sig/ont/fma/fma70573
T10 3601-3606 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T11 3614-3618 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T12 3705-3729 Body_part denotes antigen-presenting cells http://purl.org/sig/ont/fma/fma273565
T13 3724-3729 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T14 3733-3738 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T15 3745-3750 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T16 3800-3810 Body_part denotes lymph node http://purl.org/sig/ont/fma/fma5034
T17 3904-3912 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T18 3919-3923 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T19 4084-4088 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T20 4160-4168 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T21 4191-4195 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T22 4539-4547 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T23 4684-4692 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T24 5079-5092 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T25 5146-5150 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T26 5169-5180 Body_part denotes bone marrow http://purl.org/sig/ont/fma/fma9608
T27 5256-5261 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T28 5365-5370 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T29 5452-5457 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T30 5488-5493 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T31 5633-5638 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T32 5644-5655 Body_part denotes neutrophils http://purl.org/sig/ont/fma/fma62860
T33 5730-5743 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T34 5878-5902 Body_part denotes antigen-presenting cells http://purl.org/sig/ont/fma/fma273565
T35 5897-5902 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T36 5933-5943 Body_part denotes lymph node http://purl.org/sig/ont/fma/fma5034
T37 6202-6207 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T38 6214-6219 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T39 7444-7468 Body_part denotes antigen-presenting cells http://purl.org/sig/ont/fma/fma273565
T40 7463-7468 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T41 7517-7522 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T42 7546-7554 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T43 8251-8259 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T44 8262-8266 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T45 8283-8287 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T46 8480-8484 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T47 9202-9210 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T48 9220-9224 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T49 9592-9605 Body_part denotes myeloid cells http://purl.org/sig/ont/fma/fma70339
T50 9600-9605 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T51 9658-9662 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T52 9683-9687 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T53 9732-9738 Body_part denotes thymus http://purl.org/sig/ont/fma/fma9607
T54 9766-9771 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T55 9784-9802 Body_part denotes regulatory T cells http://purl.org/sig/ont/fma/fma84070
T56 9797-9802 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T57 9889-9900 Body_part denotes lymph nodes http://purl.org/sig/ont/fma/fma5034
T58 9889-9894 Body_part denotes lymph http://purl.org/sig/ont/fma/fma9671
T59 9925-9929 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 396-420 Body_part denotes respiratory and systemic http://purl.obolibrary.org/obo/UBERON_0001004
T2 3354-3360 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T3 3375-3379 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T4 3404-3409 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T5 3614-3618 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T6 3800-3810 Body_part denotes lymph node http://purl.obolibrary.org/obo/UBERON_0000029
T7 3800-3805 Body_part denotes lymph http://purl.obolibrary.org/obo/UBERON_0002391
T8 4084-4088 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T9 5079-5092 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T10 5169-5180 Body_part denotes bone marrow http://purl.obolibrary.org/obo/UBERON_0002371
T11 5730-5743 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T12 5933-5943 Body_part denotes lymph node http://purl.obolibrary.org/obo/UBERON_0000029
T13 5933-5938 Body_part denotes lymph http://purl.obolibrary.org/obo/UBERON_0002391
T14 9658-9662 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T15 9732-9738 Body_part denotes thymus http://purl.obolibrary.org/obo/UBERON_0002370
T16 9889-9900 Body_part denotes lymph nodes http://purl.obolibrary.org/obo/UBERON_0000029
T17 9889-9894 Body_part denotes lymph http://purl.obolibrary.org/obo/UBERON_0002391

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 17-25 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T2 102-110 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T3 329-338 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T4 659-667 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T5 866-874 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T6 877-886 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T7 997-1005 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T8 1018-1028 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T9 2227-2235 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T10 2744-2753 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T11 2766-2774 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T12 3119-3152 Disease denotes Severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T13 3395-3417 Disease denotes multiple organ failure http://purl.obolibrary.org/obo/MONDO_0043726
T14 3522-3531 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T15 3924-3933 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T16 4040-4048 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T17 4433-4442 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T18 4555-4561 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T19 5668-5677 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T20 6268-6277 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T21 6874-6882 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T22 6885-6894 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T23 6988-6997 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T24 7184-7192 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T25 7217-7226 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T26 7379-7391 Disease denotes Yellow Fever http://purl.obolibrary.org/obo/MONDO_0020502
T27 7659-7668 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T28 7769-7778 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T29 8021-8029 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T30 8092-8100 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T31 8103-8112 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T32 8231-8239 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T33 8982-8991 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T34 9120-9129 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T35 9428-9437 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T36 9811-9823 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T37 10725-10733 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 396-420 http://purl.obolibrary.org/obo/UBERON_0001004 denotes respiratory and systemic
T2 445-446 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T3 704-708 http://purl.obolibrary.org/obo/CLO_0008416 denotes peer
T4 704-708 http://purl.obolibrary.org/obo/CLO_0050081 denotes peer
T5 720-723 http://purl.obolibrary.org/obo/PR_000001343 denotes aim
T6 735-736 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 1033-1036 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T8 1078-1079 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 1363-1365 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T10 1802-1803 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T11 2028-2029 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T12 2216-2223 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T13 2618-2619 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T14 2620-2625 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T15 2860-2865 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T16 2902-2907 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T17 2942-2946 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T18 3008-3012 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T19 3238-3239 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T20 3318-3323 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T21 3354-3360 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T22 3375-3379 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T23 3375-3379 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T24 3404-3409 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T25 3423-3426 http://purl.obolibrary.org/obo/PR_000001343 denotes aim
T26 3558-3563 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T27 3599-3606 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T28 3614-3618 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T29 3614-3618 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T30 3724-3729 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T31 3731-3738 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T32 3743-3750 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T33 3758-3759 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T34 3800-3810 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph node
T35 3919-3923 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T36 4084-4088 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T37 4084-4088 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T38 4191-4195 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T39 4292-4293 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T40 4580-4581 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T41 4707-4708 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T42 5079-5092 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T43 5146-5150 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T44 5169-5173 http://purl.obolibrary.org/obo/UBERON_0002481 denotes bone
T45 5256-5261 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T46 5357-5370 http://purl.obolibrary.org/obo/CL_0000898 denotes naïve T cells
T47 5450-5457 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T48 5480-5493 http://purl.obolibrary.org/obo/CL_0000898 denotes naïve T cells
T49 5633-5638 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T50 5730-5743 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T51 5897-5902 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T52 5933-5943 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph node
T53 6191-6207 http://purl.obolibrary.org/obo/CL_0000911 denotes effector T cells
T54 6212-6219 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T55 6650-6651 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T56 6872-6873 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T57 7158-7159 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T58 7360-7366 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T59 7368-7369 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T60 7463-7468 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T61 7473-7474 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T62 7502-7505 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T63 7517-7522 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T64 7725-7728 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T65 7944-7949 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T66 8033-8040 http://purl.obolibrary.org/obo/NCBITaxon_9443 denotes Primate
T67 8081-8088 http://purl.obolibrary.org/obo/NCBITaxon_9479 denotes monkeys
T68 8142-8143 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T69 8260-8266 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T70 8281-8287 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T71 8447-8450 http://purl.obolibrary.org/obo/PR_000001343 denotes aim
T72 8464-8465 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T73 8478-8484 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T74 8724-8725 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T75 9026-9027 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T76 9220-9224 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T77 9600-9605 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T78 9658-9662 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T79 9658-9662 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T80 9681-9687 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T81 9732-9738 http://purl.obolibrary.org/obo/UBERON_0002370 denotes thymus
T82 9764-9771 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T83 9784-9802 http://purl.obolibrary.org/obo/CL_0000815 denotes regulatory T cells
T84 9889-9900 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph nodes
T85 9923-9929 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T86 10161-10168 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T87 10190-10195 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T88 10349-10350 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T89 10435-10440 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T90 10462-10463 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T91 10609-10613 http://purl.obolibrary.org/obo/CLO_0008416 denotes peer
T92 10609-10613 http://purl.obolibrary.org/obo/CLO_0050081 denotes peer
T93 10632-10633 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 1926-1931 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T2 2697-2704 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T3 3046-3055 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T4 3705-3712 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T5 5878-5885 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T6 6191-6199 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T7 7348-7356 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T8 7444-7451 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T9 7485-7492 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T10 7507-7509 Chemical denotes Th http://purl.obolibrary.org/obo/CHEBI_33385
T11 8211-8218 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T12 9202-9210 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T13 9225-9234 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T14 9852-9859 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T15 11334-11336 Chemical denotes Co http://purl.obolibrary.org/obo/CHEBI_27638

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 634-640 http://purl.obolibrary.org/obo/GO_0007568 denotes ageing
T2 830-846 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T3 2886-2901 http://purl.obolibrary.org/obo/GO_0044409 denotes entry into host
T4 3008-3018 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T5 3194-3216 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory responses
T6 3582-3588 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T7 3630-3647 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T8 3630-3647 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T9 5575-5580 http://purl.obolibrary.org/obo/GO_0007568 denotes aging
T10 5619-5632 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T11 5771-5793 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory responses
T12 5819-5844 http://purl.obolibrary.org/obo/GO_0002250 denotes adaptive immune responses
T13 6029-6050 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T14 6106-6130 http://purl.obolibrary.org/obo/GO_0002250 denotes adaptive immune response
T15 6115-6130 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T16 9409-9424 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T17 9523-9536 http://purl.obolibrary.org/obo/GO_0030097 denotes hematopoiesis
T18 9622-9650 http://purl.obolibrary.org/obo/GO_0002526 denotes acute inflammatory responses
T19 9811-9823 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T20 9852-9872 http://purl.obolibrary.org/obo/GO_0019882 denotes antigen presentation
T21 10490-10496 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T22 10708-10724 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-74 Sentence denotes Can an effective SARS-CoV-2 vaccine be developed for the older population?
T2 76-84 Sentence denotes Abstract
T3 85-268 Sentence denotes The emergence of SARS-CoV-2 and its inordinately rapid spread is posing severe challenges to the wellbeing of millions of people worldwide, health care systems and the global economy.
T4 269-554 Sentence denotes While many younger people experience no or mild symptoms on infection, older adults are highly susceptible to life-threatening respiratory and systemic conditions which demand a full understanding and leveraging of knowledge of the differences between immunity in young and old people.
T5 555-716 Sentence denotes Consequently, we welcome papers addressing any issues relevant to immunity and ageing in the context of SARS-CoV-2, and will endeavour to fast-track peer-review.
T6 717-952 Sentence denotes We aim to provide a platform exclusively for discussions of individual and age differences in susceptibility and immune responses to COVID caused by SARS-CoV-2 infection and how to prevent or reduce severity of disease in older adults.
T7 954-966 Sentence denotes Introduction
T8 967-1177 Sentence denotes The newly-emerged Coronavirus SARS-CoV-2 is highly infectious and has rapidly spread throughout the world with a case fatality rate (CFR) highly dependent on age and pre-existing conditions associated with age.
T9 1178-1454 Sentence denotes As more data become available, average CFRs in children appear negligible, in young adults perhaps up to 1%, but in people over 60 rising to 4%, over 70 up to 9% and over 80 even up to 18% (see, for example, https://www.cebm.net/covid-19/global-covid-19-case-fatality-rates/).
T10 1455-1738 Sentence denotes Clearly, these figures can vary tremendously from country to country, and depend on the state of health of the patients and the state of the health care system, but it is likely that this sort of age stratification reflects the general characteristics of Coronavirus disease (COVID).
T11 1739-1858 Sentence denotes Obviously, there is vigorous debate as to why this may be, but a common denominator is the waning of immunity with age.
T12 1859-2101 Sentence denotes Although much effort is currently directed at repurposing licensed drugs as anti-virals, particularly those with anti-inflammatory effects [1] this is usually viewed as a stop-gap measure and hopes are pinned on developing effective vaccines.
T13 2102-2247 Sentence denotes An unprecedented world-wide effort is channelling academic and industrial resources into the rapid production and testing of SARS-CoV-2 vaccines.
T14 2248-2529 Sentence denotes Quite apart from the potential dangers of accelerated vaccine development [2], and remembering the additional danger of immune enhancement [3], even were this successful the question remains whether the most susceptible members of the population (say, those over 60) would benefit.
T15 2531-2580 Sentence denotes COVID immunopathology and potential interventions
T16 2581-2762 Sentence denotes There is no pre-existing immunity to a virus not previously encountered except via cross-reactivity or shared viral antigen, as is sometimes the case for seasonal influenza strains.
T17 2763-2992 Sentence denotes As SARS-CoV-2 is almost certainly completely novel for at least the vast majority of people, the virus enjoys unrestrained entry into host cells which then rely on intracellular (cell-intrinsic) anti-viral defence mechanisms [4].
T18 2993-3118 Sentence denotes If these fail, cell death releases damage-associated molecules (DAMPs) and viral particles triggering inflammatory reactions.
T19 3119-3418 Sentence denotes Severe acute respiratory syndrome is caused by dysregulated over-exuberant inflammatory responses that can progress to a systemic sepsis-like “cytokine storm” [5], which together with effects of the virus also directly infecting other organs, not just the lung, can result in multiple organ failure.
T20 3419-3648 Sentence denotes The aim of prophylactic vaccination of course is to induce sufficient neutralising antibody to prevent infection and sufficient numbers of virus-specific resident memory cytotoxic T cells in the lung to prevent viral replication.
T21 3649-3812 Sentence denotes This requires the presence and efficient cooperation of antigen-presenting cells, T cells and B cells within a correctly functioning microenvironment (lymph node).
T22 3813-3998 Sentence denotes When vaccination is unable to elicit qualitatively or quantitatively sufficient protective antibody, host cell infection will still take place, and may trigger sequelae described above.
T23 3999-4255 Sentence denotes Given the rapidity and degree with which SARS-CoV-2 can cause immunopathology in the lung, vaccines would have to be highly efficient in generating neutralising antibody as well as protective cell mediated local immunity to prevent this sequence of events.
T24 4256-4471 Sentence denotes Achieving such immune protection by a vaccine is quite feasible in the young, but it may prove to be challenging in old populations as evidenced by the low efficacy of seasonal influenza vaccine in such populations.
T25 4472-4637 Sentence denotes Alternatively, adoptive immunotherapy with neutralising monoclonal antibody, as in cancer treatment, may be a possibility, and several companies are working on this.
T26 4638-4736 Sentence denotes However, repeated i.v. infusion of sufficient antibody does not seem a priori an optimal approach.
T27 4737-4900 Sentence denotes Clearly, traditional vaccination to stimulate the patient’s own response would be preferable, but how likely is it that that could be accomplished in older people?
T28 4902-4948 Sentence denotes Immunosenescence and its underlying mechanisms
T29 4949-5103 Sentence denotes Altered immune competence with increasing age, so-called immunosenescence [6], is the result of changes at multiple levels of the immune system over time.
T30 5104-5302 Sentence denotes It includes the altered balance of immune cell production in the bone marrow resulting in reduced lymphopoiesis and increased output of myeloid lineage cells which are also functionally compromised.
T31 5303-5414 Sentence denotes Thymic involution substantially reduces the output of naïve T cells and the TCR repertoire contracts over time.
T32 5415-5561 Sentence denotes Although loss of circulating naïve B cells is less profound than naïve T cells, reduced BCR repertoire diversity with age is also well recognized.
T33 5562-5794 Sentence denotes Furthermore, aging is associated with the dysfunction of innate immune cells like neutrophils at sites of infection possibly due to the poorer capacity of the adaptive immune system to reign in over-exuberant inflammatory responses.
T34 5795-5957 Sentence denotes The ability to generate adaptive immune responses is compromised by dysfunction of antigen-presenting cells and disorganised and fibrotic lymph node architecture.
T35 5958-6220 Sentence denotes Collectively, these changes prevent appropriate control of the initial inflammatory response and decrease the generation of an efficient and robust adaptive immune response which requires the production of large number of functional effector T cells and B cells.
T36 6221-6510 Sentence denotes For all these reasons, protective responses to infection or vaccination tend to be on average lower in many older adults than in the young, but there is enormous inter-individual variation in people owing to the individual variations of genetics and the history of environmental exposures.
T37 6511-6575 Sentence denotes Hence, two crucial questions are raised by these considerations:
T38 6576-6800 Sentence denotes 1) how can we measure immune and physiological status in an individual in a clinically meaningful manner and 2) how can we intervene at the crucial checkpoints thus identified in order to restore appropriate immune function?
T39 6801-7058 Sentence denotes Identification of biomarkers of protective or detrimental responses to a SARS-CoV-2 infection or vaccine and determination of the kinetic pattern of these biomarkers during the course of infection or vaccine response are critical to address these questions.
T40 7060-7094 Sentence denotes Biomarkers and vaccine requirement
T41 7095-7138 Sentence denotes There are few precedents to assist us here.
T42 7139-7243 Sentence denotes Efforts to develop a prophylactic vaccine or SARS-CoV-1 were shelved when the infection faded by itself.
T43 7244-7367 Sentence denotes There are surprisingly few data available concerning the status of immune responsiveness to truly novel antigens in humans.
T44 7368-7588 Sentence denotes A study on Yellow Fever vaccination of the elderly pointed to dysfunctional antigen-presenting cells and a dearth of antigen-specific CD4+ Th helper cells as culprits in the low antibody responses of older vaccinees [7].
T45 7589-7681 Sentence denotes Otherwise, we have to rely mostly on the large literature on seasonal influenza vaccination.
T46 7682-7857 Sentence denotes However, the problem here is that everyone has already been exposed to some strains of influenza and even newly-emerging strains such as the avian H7N1 are not entirely novel.
T47 7858-8032 Sentence denotes Nonetheless, knowledge garnered on immunity and responses to vaccination against this virus may tell us something about the capacity of older adults to respond to SARS-CoV-2.
T48 8033-8141 Sentence denotes Primate models featuring the responses of older monkeys to SARS-CoV-1 infection may also be informative [8].
T49 8142-8391 Sentence denotes A systems biology approach will be needed to identify the protective antigen/epitopes of SARS-CoV-2 for both antibody/B cell responses and T cell responses and to classify them as protective or non-protective responses to serve as useful biomarkers.
T50 8392-8565 Sentence denotes Importantly, vaccine design for the older adult should aim to stimulate a broad T and B cell response potentially overcoming reduced immune function in the older population.
T51 8567-8660 Sentence denotes How can current immunological knowledge be leveraged to protect the oldest old against COVID?
T52 8661-8958 Sentence denotes According to the above arguments, we consider it unlikely that a conventional vaccine based on young adult responses will be highly effective in COVID prophylaxis for older adults, but should be rigorously applied to everyone else to achieve herd immunity that will indirectly protect the elderly.
T53 8959-9089 Sentence denotes The ability to prevent infection by adoptive immunotherapy remains a possibility, albeit logistically and financially challenging.
T54 9090-9269 Sentence denotes Pharmacological prevention of infection by other means, for example, by blocking the interactions between viral proteins and host cell molecules acting as receptors may be useful.
T55 9270-9461 Sentence denotes Finally, various ways to improve the general immune functions in the older population should be considered and developed to strengthen the immune response to infection and vaccine in general.
T56 9462-9961 Sentence denotes These approaches could include interventions at the level of hematopoiesis to correct the skewing of output towards dysfunctional myeloid cells responsible for acute inflammatory responses in the lung, normalisation of T cell progenitor output and reconstitution of the thymus for correct selection of T cells, especially regulatory T cells to keep inflammation in check, reconstitution of antigen presentation function in the lymph nodes and re-alignment of T-B cell interactions and functionality.
T57 9962-10067 Sentence denotes In the meantime, the major benefit of vaccination will be seen at the population level in younger people.
T58 10068-10397 Sentence denotes Once herd immunity is established, the well-known effect of diluting out new hosts for acute viruses should result in the virus disappearing, with the proviso that protective immunity is retained for long enough (this is not yet established) and reinfection is not introduced from a location where new hosts were still available.
T59 10398-10512 Sentence denotes And with the linked proviso that the virus does not mutate into a form against which immune memory is not present.
T60 10513-10829 Sentence denotes We welcome papers addressing any of the issues discussed above and will endeavour to fast-track peer-review to provide a platform exclusively for discussions of individual and age differences in immune responses SARS-CoV-2 and susceptibility to COVID and how to prevent or reduce severity of disease in older adults.
T61 10831-10847 Sentence denotes Publisher’s Note
T62 10848-10966 Sentence denotes Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
T63 10968-10984 Sentence denotes Acknowledgements
T64 10985-10990 Sentence denotes None.
T65 10992-11014 Sentence denotes Authors’ contributions
T66 11015-11061 Sentence denotes Both authors wrote and revised the manuscript.
T67 11062-11115 Sentence denotes The author(s) read and approved the final manuscript.
T68 11117-11137 Sentence denotes Authors’ information
T69 11138-11161 Sentence denotes No further information.
T70 11163-11170 Sentence denotes Funding
T71 11171-11191 Sentence denotes No specific funding.
T72 11193-11227 Sentence denotes Availability of data and materials
T73 11228-11243 Sentence denotes Not applicable.
T74 11245-11287 Sentence denotes Ethics approval and consent to participate
T75 11288-11303 Sentence denotes Not applicable.
T76 11305-11328 Sentence denotes Consent for publication
T77 11329-11377 Sentence denotes Both Co-Editors-in-Chief consent to publication.
T78 11379-11398 Sentence denotes Competing interests
T79 11399-11443 Sentence denotes Both authors declare no competing interests.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 3249-3255 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T2 3262-3276 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T3 4555-4561 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T4 7386-7391 Phenotype denotes Fever http://purl.obolibrary.org/obo/HP_0001945