PMC:7144273 / 48425-49156 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T439","span":{"begin":139,"end":148},"obj":"Body_part"},{"id":"T440","span":{"begin":144,"end":148},"obj":"Body_part"},{"id":"T441","span":{"begin":328,"end":337},"obj":"Body_part"},{"id":"T442","span":{"begin":333,"end":337},"obj":"Body_part"},{"id":"T443","span":{"begin":367,"end":372},"obj":"Body_part"},{"id":"T444","span":{"begin":414,"end":419},"obj":"Body_part"},{"id":"T445","span":{"begin":430,"end":435},"obj":"Body_part"},{"id":"T446","span":{"begin":436,"end":440},"obj":"Body_part"},{"id":"T447","span":{"begin":492,"end":497},"obj":"Body_part"},{"id":"T448","span":{"begin":574,"end":579},"obj":"Body_part"}],"attributes":[{"id":"A439","pred":"fma_id","subj":"T439","obj":"http://purl.org/sig/ont/fma/fma63368"},{"id":"A440","pred":"fma_id","subj":"T440","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A441","pred":"fma_id","subj":"T441","obj":"http://purl.org/sig/ont/fma/fma63368"},{"id":"A442","pred":"fma_id","subj":"T442","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A443","pred":"fma_id","subj":"T443","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A444","pred":"fma_id","subj":"T444","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A445","pred":"fma_id","subj":"T445","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A446","pred":"fma_id","subj":"T446","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A447","pred":"fma_id","subj":"T447","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A448","pred":"fma_id","subj":"T448","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"5 06-03-2020; 10-04-2020 to 10-11-2020 2Not recruiting NCT04299152;https://clinicaltrials.gov/ct2/show/NCT04299152 Clinical application of stem cell educator therapy for the treatment of viral inflammation caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) CB-SCs 20 Experimental group: combination product: stem cell educator-treated mononuclear cells apheresis therapy circulates a patient's blood through a blood cell separator, briefly cocultures the patient's immune cells with adherent CB-SCs in vitro, and returns the “educated” autologous immune cells to the patient's circulationControl group: conventional treatment: regular treatments, only addressing their symptoms, such as reducing fever and cough"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T159","span":{"begin":414,"end":419},"obj":"Body_part"},{"id":"T160","span":{"begin":430,"end":435},"obj":"Body_part"}],"attributes":[{"id":"A159","pred":"uberon_id","subj":"T159","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A160","pred":"uberon_id","subj":"T160","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"}],"text":"5 06-03-2020; 10-04-2020 to 10-11-2020 2Not recruiting NCT04299152;https://clinicaltrials.gov/ct2/show/NCT04299152 Clinical application of stem cell educator therapy for the treatment of viral inflammation caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) CB-SCs 20 Experimental group: combination product: stem cell educator-treated mononuclear cells apheresis therapy circulates a patient's blood through a blood cell separator, briefly cocultures the patient's immune cells with adherent CB-SCs in vitro, and returns the “educated” autologous immune cells to the patient's circulationControl group: conventional treatment: regular treatments, only addressing their symptoms, such as reducing fever and cough"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T314","span":{"begin":193,"end":205},"obj":"Disease"},{"id":"T315","span":{"begin":216,"end":263},"obj":"Disease"},{"id":"T316","span":{"begin":216,"end":249},"obj":"Disease"},{"id":"T317","span":{"begin":265,"end":273},"obj":"Disease"},{"id":"T318","span":{"begin":265,"end":269},"obj":"Disease"}],"attributes":[{"id":"A314","pred":"mondo_id","subj":"T314","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A315","pred":"mondo_id","subj":"T315","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A316","pred":"mondo_id","subj":"T316","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A317","pred":"mondo_id","subj":"T317","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A318","pred":"mondo_id","subj":"T318","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"5 06-03-2020; 10-04-2020 to 10-11-2020 2Not recruiting NCT04299152;https://clinicaltrials.gov/ct2/show/NCT04299152 Clinical application of stem cell educator therapy for the treatment of viral inflammation caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) CB-SCs 20 Experimental group: combination product: stem cell educator-treated mononuclear cells apheresis therapy circulates a patient's blood through a blood cell separator, briefly cocultures the patient's immune cells with adherent CB-SCs in vitro, and returns the “educated” autologous immune cells to the patient's circulationControl group: conventional treatment: regular treatments, only addressing their symptoms, such as reducing fever and cough"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T671","span":{"begin":0,"end":4},"obj":"http://purl.obolibrary.org/obo/CLO_0001404"},{"id":"T672","span":{"begin":31,"end":33},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T673","span":{"begin":139,"end":148},"obj":"http://purl.obolibrary.org/obo/CL_0000034"},{"id":"T674","span":{"begin":328,"end":337},"obj":"http://purl.obolibrary.org/obo/CL_0000034"},{"id":"T675","span":{"begin":355,"end":372},"obj":"http://purl.obolibrary.org/obo/CL_0000842"},{"id":"T676","span":{"begin":402,"end":403},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T677","span":{"begin":414,"end":419},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T678","span":{"begin":414,"end":419},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T679","span":{"begin":428,"end":429},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T680","span":{"begin":430,"end":435},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T681","span":{"begin":436,"end":440},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T682","span":{"begin":492,"end":497},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T683","span":{"begin":574,"end":579},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"5 06-03-2020; 10-04-2020 to 10-11-2020 2Not recruiting NCT04299152;https://clinicaltrials.gov/ct2/show/NCT04299152 Clinical application of stem cell educator therapy for the treatment of viral inflammation caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) CB-SCs 20 Experimental group: combination product: stem cell educator-treated mononuclear cells apheresis therapy circulates a patient's blood through a blood cell separator, briefly cocultures the patient's immune cells with adherent CB-SCs in vitro, and returns the “educated” autologous immune cells to the patient's circulationControl group: conventional treatment: regular treatments, only addressing their symptoms, such as reducing fever and cough"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T242","span":{"begin":124,"end":135},"obj":"Chemical"},{"id":"T243","span":{"begin":300,"end":305},"obj":"Chemical"},{"id":"T244","span":{"begin":616,"end":621},"obj":"Chemical"}],"attributes":[{"id":"A242","pred":"chebi_id","subj":"T242","obj":"http://purl.obolibrary.org/obo/CHEBI_33232"},{"id":"A243","pred":"chebi_id","subj":"T243","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"},{"id":"A244","pred":"chebi_id","subj":"T244","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"}],"text":"5 06-03-2020; 10-04-2020 to 10-11-2020 2Not recruiting NCT04299152;https://clinicaltrials.gov/ct2/show/NCT04299152 Clinical application of stem cell educator therapy for the treatment of viral inflammation caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) CB-SCs 20 Experimental group: combination product: stem cell educator-treated mononuclear cells apheresis therapy circulates a patient's blood through a blood cell separator, briefly cocultures the patient's immune cells with adherent CB-SCs in vitro, and returns the “educated” autologous immune cells to the patient's circulationControl group: conventional treatment: regular treatments, only addressing their symptoms, such as reducing fever and cough"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T90","span":{"begin":193,"end":205},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"5 06-03-2020; 10-04-2020 to 10-11-2020 2Not recruiting NCT04299152;https://clinicaltrials.gov/ct2/show/NCT04299152 Clinical application of stem cell educator therapy for the treatment of viral inflammation caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) CB-SCs 20 Experimental group: combination product: stem cell educator-treated mononuclear cells apheresis therapy circulates a patient's blood through a blood cell separator, briefly cocultures the patient's immune cells with adherent CB-SCs in vitro, and returns the “educated” autologous immune cells to the patient's circulationControl group: conventional treatment: regular treatments, only addressing their symptoms, such as reducing fever and cough"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T74","span":{"begin":716,"end":721},"obj":"Phenotype"},{"id":"T75","span":{"begin":726,"end":731},"obj":"Phenotype"}],"attributes":[{"id":"A74","pred":"hp_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A75","pred":"hp_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/HP_0012735"}],"text":"5 06-03-2020; 10-04-2020 to 10-11-2020 2Not recruiting NCT04299152;https://clinicaltrials.gov/ct2/show/NCT04299152 Clinical application of stem cell educator therapy for the treatment of viral inflammation caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) CB-SCs 20 Experimental group: combination product: stem cell educator-treated mononuclear cells apheresis therapy circulates a patient's blood through a blood cell separator, briefly cocultures the patient's immune cells with adherent CB-SCs in vitro, and returns the “educated” autologous immune cells to the patient's circulationControl group: conventional treatment: regular treatments, only addressing their symptoms, such as reducing fever and cough"}

{"project":"LitCovid-sentences","denotations":[{"id":"T215","span":{"begin":0,"end":731},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"5 06-03-2020; 10-04-2020 to 10-11-2020 2Not recruiting NCT04299152;https://clinicaltrials.gov/ct2/show/NCT04299152 Clinical application of stem cell educator therapy for the treatment of viral inflammation caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) CB-SCs 20 Experimental group: combination product: stem cell educator-treated mononuclear cells apheresis therapy circulates a patient's blood through a blood cell separator, briefly cocultures the patient's immune cells with adherent CB-SCs in vitro, and returns the “educated” autologous immune cells to the patient's circulationControl group: conventional treatment: regular treatments, only addressing their symptoms, such as reducing fever and cough"}