PMC:7144273 / 17296-18890
Annnotations
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T504 | 133-144 | UBERON:0001004;NCBITaxon:11886 | denotes | respiratory |
| T505 | 145-150 | NCBITaxon:10239 | denotes | virus |
| T506 | 198-207 | NCBITaxon:7719 | denotes | influenza |
| T507 | 208-215 | NCBITaxon:10239 | denotes | viruses |
| T508 | 291-302 | NCBITaxon:11118 | denotes | coronavirus |
| T509 | 303-314 | UBERON:0001004 | denotes | respiratory |
| T510 | 372-376 | DG_47 | denotes | MSCs |
| T511 | 416-427 | UBERON:0001004 | denotes | respiratory |
| T512 | 442-446 | NCBITaxon:10088 | denotes | mice |
| T513 | 544-548 | NCBITaxon:10088 | denotes | mice |
| T514 | 569-575 | NCBITaxon:39107 | denotes | murine |
| T515 | 579-583 | DG_47 | denotes | MSCs |
| T516 | 598-603 | SP_6;NCBITaxon:9606 | denotes | human |
| T517 | 607-611 | DG_47 | denotes | MSCs |
| T518 | 615-619 | UBERON:0002048 | denotes | lung |
| T519 | 638-643 | NCBITaxon:10088 | denotes | mouse |
| T520 | 711-715 | DG_47 | denotes | MSCs |
| T521 | 740-745 | NCBITaxon:10088 | denotes | mouse |
| T522 | 798-803 | NCBITaxon:10239 | denotes | virus |
| T523 | 905-909 | UBERON:0002048 | denotes | lung |
| T524 | 1035-1043 | CHEBI:60809;CHEBI:60809 | denotes | adjuvant |
| T525 | 1057-1068 | CHEBI:7798;CHEBI:7798 | denotes | oseltamivir |
| T526 | 1135-1140 | NCBITaxon:10239 | denotes | virus |
| T527 | 1294-1299 | SP_6;NCBITaxon:9606 | denotes | human |
| T528 | 1304-1309 | NCBITaxon:10088 | denotes | mouse |
| T529 | 1310-1314 | DG_47 | denotes | MSCs |
| T530 | 1328-1333 | NCBITaxon:10088 | denotes | mouse |
| T531 | 1433-1438 | NCBITaxon:10088 | denotes | mouse |
| T532 | 1460-1464 | UBERON:0002048 | denotes | lung |
| T533 | 1491-1495 | NCBITaxon:10088 | denotes | mice |
| T534 | 1506-1510 | DG_47 | denotes | MSCs |
| T535 | 1546-1550 | UBERON:0002048 | denotes | lung |
| T31003 | 133-144 | UBERON:0001004;NCBITaxon:11886 | denotes | respiratory |
| T20547 | 145-150 | NCBITaxon:10239 | denotes | virus |
| T51600 | 198-207 | NCBITaxon:7719 | denotes | influenza |
| T25224 | 208-215 | NCBITaxon:10239 | denotes | viruses |
| T49950 | 291-302 | NCBITaxon:11118 | denotes | coronavirus |
| T13028 | 303-314 | UBERON:0001004 | denotes | respiratory |
| T61703 | 372-376 | DG_47 | denotes | MSCs |
| T87821 | 416-427 | UBERON:0001004 | denotes | respiratory |
| T46777 | 442-446 | NCBITaxon:10088 | denotes | mice |
| T93835 | 544-548 | NCBITaxon:10088 | denotes | mice |
| T60525 | 569-575 | NCBITaxon:39107 | denotes | murine |
| T58514 | 579-583 | DG_47 | denotes | MSCs |
| T21895 | 598-603 | SP_6;NCBITaxon:9606 | denotes | human |
| T79556 | 607-611 | DG_47 | denotes | MSCs |
| T62357 | 615-619 | UBERON:0002048 | denotes | lung |
| T95816 | 638-643 | NCBITaxon:10088 | denotes | mouse |
| T76320 | 711-715 | DG_47 | denotes | MSCs |
| T29456 | 740-745 | NCBITaxon:10088 | denotes | mouse |
| T97121 | 798-803 | NCBITaxon:10239 | denotes | virus |
| T89997 | 905-909 | UBERON:0002048 | denotes | lung |
| T6878 | 1035-1043 | CHEBI:60809;CHEBI:60809 | denotes | adjuvant |
| T93200 | 1057-1068 | CHEBI:7798;CHEBI:7798 | denotes | oseltamivir |
| T70987 | 1135-1140 | NCBITaxon:10239 | denotes | virus |
| T32429 | 1294-1299 | SP_6;NCBITaxon:9606 | denotes | human |
| T92217 | 1304-1309 | NCBITaxon:10088 | denotes | mouse |
| T24717 | 1310-1314 | DG_47 | denotes | MSCs |
| T64488 | 1328-1333 | NCBITaxon:10088 | denotes | mouse |
| T30934 | 1433-1438 | NCBITaxon:10088 | denotes | mouse |
| T56264 | 1460-1464 | UBERON:0002048 | denotes | lung |
| T30704 | 1491-1495 | NCBITaxon:10088 | denotes | mice |
| T82864 | 1506-1510 | DG_47 | denotes | MSCs |
| T63085 | 1546-1550 | UBERON:0002048 | denotes | lung |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T160 | 615-619 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T161 | 905-909 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T162 | 1460-1464 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T163 | 1546-1550 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T45 | 615-619 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T46 | 905-909 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T47 | 1460-1464 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T48 | 1546-1550 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T139 | 145-161 | Disease | denotes | virus infections | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T140 | 198-207 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T141 | 303-325 | Disease | denotes | respiratory infections | http://purl.obolibrary.org/obo/MONDO_0024355 |
| T142 | 406-415 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T143 | 416-438 | Disease | denotes | respiratory infections | http://purl.obolibrary.org/obo/MONDO_0024355 |
| T144 | 620-626 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T145 | 845-854 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T146 | 910-922 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T147 | 1465-1471 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T148 | 1527-1536 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T149 | 1551-1557 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T242 | 24-25 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T243 | 145-150 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T244 | 208-215 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T245 | 492-493 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T246 | 576-578 | http://purl.obolibrary.org/obo/CLO_0001997 | denotes | BM |
| T247 | 598-603 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T248 | 604-606 | http://purl.obolibrary.org/obo/CLO_0001997 | denotes | BM |
| T249 | 615-619 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T250 | 615-619 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T251 | 638-643 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
| T252 | 798-803 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T253 | 905-909 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T254 | 905-909 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T255 | 1135-1140 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T256 | 1294-1299 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T257 | 1304-1309 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
| T258 | 1433-1438 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
| T259 | 1460-1464 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T260 | 1460-1464 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T261 | 1546-1550 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T262 | 1546-1550 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T104 | 1035-1043 | Chemical | denotes | adjuvant | http://purl.obolibrary.org/obo/CHEBI_60809 |
| T105 | 1057-1068 | Chemical | denotes | oseltamivir | http://purl.obolibrary.org/obo/CHEBI_7798 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T59 | 910-922 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T22 | 303-325 | Phenotype | denotes | respiratory infections | http://purl.obolibrary.org/obo/HP_0011947 |
| T23 | 416-438 | Phenotype | denotes | respiratory infections | http://purl.obolibrary.org/obo/HP_0011947 |
MyTest
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32265310-23967240-29390471 | 464-466 | 23967240 | denotes | 37 |
| 32265310-25038188-29390472 | 1217-1219 | 25038188 | denotes | 38 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32265310-23967240-29390471 | 464-466 | 23967240 | denotes | 37 |
| 32265310-25038188-29390472 | 1217-1219 | 25038188 | denotes | 38 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T87 | 0-162 | Sentence | denotes | However, there are only a small number of pre-clinical studies investigating effects of MSC administration in pre-clinical models of respiratory virus infections. |
| T88 | 163-336 | Sentence | denotes | These have been further limited to influenza viruses, have produced conflicting results, and have not as yet directly addressed coronavirus respiratory infections (table 1). |
| T89 | 337-447 | Sentence | denotes | Notably, two earlier studies found MSCs not to be protective against influenza respiratory infections in mice. |
| T90 | 448-687 | Sentence | denotes | Darwish et al. [37] assessed the effects of a single systemic administration in immunocompetent mice of either syngeneic murine BM-MSCs or xenogeneic human BM-MSCs on lung injury induced by mouse-adapted H1N1 or swine-origin pandemic H1N1. |
| T91 | 688-863 | Sentence | denotes | Two different doses of MSCs (2.5×105 or 5×105 cells·mouse−1) were administered at different time-points after virus administration (days −2, 0, 2 and 5 post infection (p.i.)). |
| T92 | 864-1191 | Sentence | denotes | Using survival and different measures of lung inflammation as outcome end-points on day 7 p.i., neither syngeneic nor xenogeneic MSC administration, either alone or as an adjuvant therapy with oseltamivir, was effective either when administered prophylactically prior to virus inoculation, or when therapeutically administered. |
| T93 | 1192-1496 | Sentence | denotes | Similarly, Gotts et al. [38] assessed the effect of both systemic and intratracheal administration of human and mouse MSCs (5×105 cells·mouse−1), administered in two doses, either earlier (days 2 and 3 p.i.) or later (days 5 and 6 p.i.), in mouse-adapted H1N1-induced lung injury in immunocompetent mice. |
| T94 | 1497-1594 | Sentence | denotes | However, MSCs did not improve influenza-mediated lung injury, regardless of administration route. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 591 | 198-215 | Species | denotes | influenza viruses | Tax:11308 |
| 592 | 442-446 | Species | denotes | mice | Tax:10090 |
| 593 | 544-548 | Species | denotes | mice | Tax:10090 |
| 594 | 569-575 | Species | denotes | murine | Tax:10090 |
| 595 | 598-603 | Species | denotes | human | Tax:9606 |
| 596 | 638-643 | Species | denotes | mouse | Tax:10090 |
| 597 | 652-656 | Species | denotes | H1N1 | Tax:114727 |
| 598 | 660-665 | Species | denotes | swine | Tax:9823 |
| 599 | 682-686 | Species | denotes | H1N1 | Tax:114727 |
| 600 | 740-745 | Species | denotes | mouse | Tax:10090 |
| 601 | 1294-1299 | Species | denotes | human | Tax:9606 |
| 602 | 1304-1309 | Species | denotes | mouse | Tax:10090 |
| 603 | 1328-1333 | Species | denotes | mouse | Tax:10090 |
| 604 | 1433-1438 | Species | denotes | mouse | Tax:10090 |
| 605 | 1447-1451 | Species | denotes | H1N1 | Tax:114727 |
| 606 | 1491-1495 | Species | denotes | mice | Tax:10090 |
| 607 | 46-54 | Species | denotes | clinical | Tax:191496 |
| 608 | 114-122 | Species | denotes | clinical | Tax:191496 |
| 609 | 406-415 | Species | denotes | influenza | Tax:11320 |
| 610 | 1527-1536 | Species | denotes | influenza | Tax:11320 |
| 611 | 1057-1068 | Chemical | denotes | oseltamivir | MESH:D053139 |
| 612 | 133-161 | Disease | denotes | respiratory virus infections | |
| 613 | 291-325 | Disease | denotes | coronavirus respiratory infections | MESH:D018352 |
| 614 | 416-438 | Disease | denotes | respiratory infections | MESH:D012141 |
| 615 | 615-626 | Disease | denotes | lung injury | MESH:D055370 |
| 616 | 845-854 | Disease | denotes | infection | MESH:D007239 |
| 617 | 905-922 | Disease | denotes | lung inflammation | MESH:D011014 |
| 618 | 1460-1471 | Disease | denotes | lung injury | MESH:D055370 |
| 619 | 1546-1557 | Disease | denotes | lung injury | MESH:D055370 |