PMC:7143804 / 9319-10920
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 95 | 172-179 | Chemical | denotes | polymer | MESH:D011108 |
| 96 | 698-703 | Chemical | denotes | metal | MESH:D008670 |
| 97 | 735-740 | Chemical | denotes | metal | MESH:D008670 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T21 | 186-189 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
| T22 | 972-975 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T19 | 301-330 | Disease | denotes | Sexually Transmitted Diseases | http://purl.obolibrary.org/obo/MONDO_0021681 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T68 | 158-159 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T69 | 282-294 | http://purl.obolibrary.org/obo/OBI_0000245 | denotes | Organization |
| T70 | 378-385 | http://purl.obolibrary.org/obo/OBI_0000968 | denotes | Devices |
| T71 | 409-410 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T72 | 594-595 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T73 | 596-602 | http://purl.obolibrary.org/obo/OBI_0000968 | denotes | device |
| T74 | 653-660 | http://purl.obolibrary.org/obo/CLO_0009985 | denotes | focuses |
| T75 | 1013-1014 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T76 | 1254-1260 | http://purl.obolibrary.org/obo/OBI_0000968 | denotes | device |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T56 | 172-179 | Chemical | denotes | polymer | http://purl.obolibrary.org/obo/CHEBI_33839|http://purl.obolibrary.org/obo/CHEBI_60027 |
| T58 | 186-189 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
| T59 | 787-790 | Chemical | denotes | HDA | http://purl.obolibrary.org/obo/CHEBI_17314 |
| T60 | 889-892 | Chemical | denotes | MDA | http://purl.obolibrary.org/obo/CHEBI_566274 |
| T61 | 972-975 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T6 | 186-203 | http://purl.obolibrary.org/obo/GO_0006277 | denotes | DNA amplification |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T79 | 0-4 | Sentence | denotes | 1.2. |
| T80 | 5-23 | Sentence | denotes | The Presented Work |
| T81 | 24-377 | Sentence | denotes | The work presented at the 4th Microfluidic Handling Systems conference and which is extended in this paper aims at the development of a disposable, polymer-based DNA amplification lab-on-chip system with integrated resistive heater based on the World Health Organization (WHO) Sexually Transmitted Diseases Diagnostics Initiative (SDI) ASSURED criteria. |
| T82 | 378-565 | Sentence | denotes | Devices which are ASSURED are (A) affordable, (S) sensitive, (S) specific, (U) user-friendly, (R) robust and rapid, (E) equipment-free, and (D) deliverable to those who need them [20,49]. |
| T83 | 566-641 | Sentence | denotes | The first step towards such a device is the development of the chip itself. |
| T84 | 642-741 | Sentence | denotes | This paper focuses on the choice of substrate material, metal deposition method, and type of metal. |
| T85 | 742-899 | Sentence | denotes | Although, it is mentioned above that PCR and HDA are sequence specific, the reaction chosen is the isothermal multiple displacement amplification (MDA) [50]. |
| T86 | 900-1178 | Sentence | denotes | This reaction is more straightforward [51], as it amplifies any present DNA, and is therefore better suitable as a proof-of-principle amplification reaction to show the functioning of the integrated heater and the biocompatibility of the substrate after the fabrication process. |
| T87 | 1179-1318 | Sentence | denotes | The use of an isothermal amplification technique also simplifies the final device and lowers its footprint, as there are no pumps required. |
| T88 | 1319-1474 | Sentence | denotes | In this research, external analysis methods are used which do not contribute to the WHO-SDI ASSURED criteria due to their bulkiness, costs, and difficulty. |
| T89 | 1475-1601 | Sentence | denotes | However, suggestions and comments on the integration of low-cost detection methods, which are ASSURED, are given in Section 5. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32106462-22704369-69893309 | 558-560 | 22704369 | denotes | 20 |
| 32106462-16786504-69893310 | 895-897 | 16786504 | denotes | 50 |