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PMC:7143804 / 55691-56371 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T138 198-201 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T139 653-656 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T424 65-71 http://purl.obolibrary.org/obo/CLO_0001627 denotes (a), a
T425 105-106 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T426 508-509 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T40045 42-45 Chemical denotes MDA http://purl.obolibrary.org/obo/CHEBI_566274
T885 198-201 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T8145 346-351 Chemical denotes bases http://purl.obolibrary.org/obo/CHEBI_22695
T5029 653-656 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T500 0-55 Sentence denotes Figure 1 Schematic representation of the MDA reaction.
T501 56-94 Sentence denotes In panel (a), a dsDNA strand is shown.
T502 95-139 Sentence denotes In panel (b), denaturation happens at 95 °C.
T503 140-255 Sentence denotes In panel (c), the random hexamer-primers (purple) and ϕ29 DNA polymerase (blue arrow) bind to the initiation sites.
T504 256-372 Sentence denotes In panel (d), the amplification is performed by the polymerase, which binds complementary bases to the ssDNA strand.
T505 373-493 Sentence denotes In panel (e), the polymerase encounters another hexamer binded to an initiation site and starts lifting up this hexamer.
T506 494-625 Sentence denotes In panel (f), a hexamer binds to the displaced ssDNA strands and the polymerase starts the amplification from this initiation site.
T507 626-680 Sentence denotes For clarity, the amplified DNA is bordered with black.