PMC:7143804 / 48864-55689
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 313 | 1762-1770 | Gene | denotes | helicase | Gene:164045 |
| 314 | 1748-1751 | Chemical | denotes | H2O | |
| 315 | 1752-1757 | Chemical | denotes | water | MESH:D014867 |
| 316 | 1896-1904 | Chemical | denotes | nitrogen | MESH:D009584 |
| 317 | 1951-1989 | Disease | denotes | reaction PDMS polydimethylsiloxane PID | MESH:D064420 |
| 319 | 2583-2588 | Chemical | denotes | Water | MESH:D014867 |
| 321 | 2593-2596 | Chemical | denotes | H2O | |
| 323 | 3471-3476 | Chemical | denotes | water | MESH:D014867 |
| 325 | 4063-4086 | Chemical | denotes | Cyclic Olefin Copolymer | |
| 329 | 5235-5240 | Chemical | denotes | metal | MESH:D008670 |
| 330 | 5250-5253 | Chemical | denotes | COC | |
| 331 | 5396-5401 | Chemical | denotes | metal | MESH:D008670 |
| 333 | 5511-5513 | Chemical | denotes | Au | MESH:D006046 |
| 337 | 5628-5631 | Chemical | denotes | TCR | |
| 338 | 5718-5721 | Chemical | denotes | TCR | |
| 339 | 5729-5734 | Chemical | denotes | metal | MESH:D008670 |
| 341 | 5817-5819 | Chemical | denotes | Au | MESH:D006046 |
| 349 | 6187-6189 | Gene | denotes | μL | Gene:4591 |
| 350 | 6181-6183 | Gene | denotes | μL | Gene:4591 |
| 351 | 6175-6177 | Gene | denotes | μL | Gene:4591 |
| 352 | 6169-6171 | Gene | denotes | μL | Gene:4591 |
| 353 | 6163-6165 | Gene | denotes | μL | Gene:4591 |
| 354 | 6157-6159 | Gene | denotes | μL | Gene:4591 |
| 355 | 6138-6143 | Chemical | denotes | Water | MESH:D014867 |
| 363 | 6702-6704 | Gene | denotes | μL | Gene:4591 |
| 364 | 6732-6734 | Gene | denotes | μL | Gene:4591 |
| 365 | 6726-6728 | Gene | denotes | μL | Gene:4591 |
| 366 | 6720-6722 | Gene | denotes | μL | Gene:4591 |
| 367 | 6714-6716 | Gene | denotes | μL | Gene:4591 |
| 368 | 6708-6710 | Gene | denotes | μL | Gene:4591 |
| 369 | 6683-6688 | Chemical | denotes | Water | MESH:D014867 |
LitCovid_Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2 | 1546-1549 | https://glytoucan.org/Structures/Glycans/G00063MO | denotes | CAD |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T98 | 1572-1575 | Body_part | denotes | CAM | http://purl.org/sig/ont/fma/fma67214 |
| T99 | 1696-1699 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
| T100 | 1700-1721 | Body_part | denotes | deoxyribonucleic acid | http://purl.org/sig/ont/fma/fma74412 |
| T101 | 1744-1747 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
| T102 | 2065-2068 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T103 | 2069-2085 | Body_part | denotes | ribonucleic acid | http://purl.org/sig/ont/fma/fma67095 |
| T104 | 2141-2144 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
| T105 | 2286-2292 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
| T106 | 2338-2346 | Body_part | denotes | Appendix | http://purl.org/sig/ont/fma/fma14542 |
| T107 | 2380-2382 | Body_part | denotes | A1 | http://purl.org/sig/ont/fma/fma66592 |
| T108 | 2409-2412 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
| T109 | 2497-2505 | Body_part | denotes | Appendix | http://purl.org/sig/ont/fma/fma14542 |
| T110 | 2569-2577 | Body_part | denotes | Appendix | http://purl.org/sig/ont/fma/fma14542 |
| T111 | 2693-2695 | Body_part | denotes | A1 | http://purl.org/sig/ont/fma/fma66592 |
| T112 | 2770-2772 | Body_part | denotes | A2 | http://purl.org/sig/ont/fma/fma66595 |
| T113 | 2835-2837 | Body_part | denotes | A3 | http://purl.org/sig/ont/fma/fma66599 |
| T114 | 3095-3097 | Body_part | denotes | A1 | http://purl.org/sig/ont/fma/fma66592 |
| T115 | 3100-3102 | Body_part | denotes | A1 | http://purl.org/sig/ont/fma/fma66592 |
| T116 | 3207-3209 | Body_part | denotes | A2 | http://purl.org/sig/ont/fma/fma66595 |
| T117 | 3313-3315 | Body_part | denotes | A3 | http://purl.org/sig/ont/fma/fma66599 |
| T118 | 3436-3438 | Body_part | denotes | A1 | http://purl.org/sig/ont/fma/fma66592 |
| T119 | 4049-4057 | Body_part | denotes | Appendix | http://purl.org/sig/ont/fma/fma14542 |
| T120 | 4163-4165 | Body_part | denotes | A2 | http://purl.org/sig/ont/fma/fma66595 |
| T121 | 4487-4491 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
| T122 | 4605-4607 | Body_part | denotes | A2 | http://purl.org/sig/ont/fma/fma66595 |
| T123 | 4874-4876 | Body_part | denotes | A6 | http://purl.org/sig/ont/fma/fma66574 |
| T124 | 4921-4923 | Body_part | denotes | A6 | http://purl.org/sig/ont/fma/fma66574 |
| T125 | 4938-4946 | Body_part | denotes | Appendix | http://purl.org/sig/ont/fma/fma14542 |
| T126 | 5134-5142 | Body_part | denotes | Appendix | http://purl.org/sig/ont/fma/fma14542 |
| T127 | 5465-5467 | Body_part | denotes | A2 | http://purl.org/sig/ont/fma/fma66595 |
| T128 | 5522-5530 | Body_part | denotes | Appendix | http://purl.org/sig/ont/fma/fma14542 |
| T129 | 5571-5573 | Body_part | denotes | A2 | http://purl.org/sig/ont/fma/fma66595 |
| T130 | 5749-5751 | Body_part | denotes | A3 | http://purl.org/sig/ont/fma/fma66599 |
| T131 | 5931-5939 | Body_part | denotes | Appendix | http://purl.org/sig/ont/fma/fma14542 |
| T132 | 6048-6050 | Body_part | denotes | A3 | http://purl.org/sig/ont/fma/fma66599 |
| T133 | 6123-6126 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
| T134 | 6201-6204 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
| T135 | 6260-6263 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
| T136 | 6310-6318 | Body_part | denotes | Appendix | http://purl.org/sig/ont/fma/fma14542 |
| T137 | 6668-6671 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T18 | 6191-6195 | Body_part | denotes | Tube | http://purl.obolibrary.org/obo/UBERON_0000025 |
| T19 | 6223-6227 | Body_part | denotes | Tube | http://purl.obolibrary.org/obo/UBERON_0000025 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T38 | 314-317 | Disease | denotes | TCO | http://purl.obolibrary.org/obo/MONDO_0011312 |
| T39 | 1546-1549 | Disease | denotes | CAD | http://purl.obolibrary.org/obo/MONDO_0005010|http://purl.obolibrary.org/obo/MONDO_0018922 |
| T41 | 1605-1608 | Disease | denotes | CNC | http://purl.obolibrary.org/obo/MONDO_0015285|http://purl.obolibrary.org/obo/MONDO_0019134 |
| T43 | 1682-1684 | Disease | denotes | DI | http://purl.obolibrary.org/obo/MONDO_0018849 |
| T44 | 1986-1989 | Disease | denotes | PID | http://purl.obolibrary.org/obo/MONDO_0000922 |
| T45 | 2149-2178 | Disease | denotes | Sexually Transmitted Diseases | http://purl.obolibrary.org/obo/MONDO_0021681 |
| T46 | 4392-4394 | Disease | denotes | MI | http://purl.obolibrary.org/obo/MONDO_0005068 |
| T47 | 6135-6137 | Disease | denotes | DI | http://purl.obolibrary.org/obo/MONDO_0018849 |
| T48 | 6680-6682 | Disease | denotes | DI | http://purl.obolibrary.org/obo/MONDO_0018849 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T348 | 1605-1608 | http://purl.obolibrary.org/obo/UBERON_0003099 | denotes | CNC |
| T349 | 1879-1881 | http://purl.obolibrary.org/obo/CLO_0007815 | denotes | Mo |
| T350 | 2324-2336 | http://purl.obolibrary.org/obo/OBI_0000245 | denotes | Organization |
| T351 | 2347-2348 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T352 | 2506-2507 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T353 | 2578-2579 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T354 | 2735-2737 | http://purl.obolibrary.org/obo/PR_000005794 | denotes | CP |
| T355 | 2770-2772 | http://purl.obolibrary.org/obo/CLO_0001562 | denotes | A2 |
| T356 | 2835-2837 | http://purl.obolibrary.org/obo/CLO_0001577 | denotes | A3 |
| T357 | 2911-2913 | http://purl.obolibrary.org/obo/PR_000005794 | denotes | CP |
| T358 | 3207-3209 | http://purl.obolibrary.org/obo/CLO_0001562 | denotes | A2 |
| T359 | 3211-3213 | http://purl.obolibrary.org/obo/PR_000005794 | denotes | CP |
| T360 | 3313-3315 | http://purl.obolibrary.org/obo/CLO_0001577 | denotes | A3 |
| T361 | 3417-3419 | http://purl.obolibrary.org/obo/PR_000005794 | denotes | CP |
| T362 | 4058-4059 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T363 | 4163-4165 | http://purl.obolibrary.org/obo/CLO_0001562 | denotes | A2 |
| T364 | 4213-4216 | http://purl.obolibrary.org/obo/CLO_0007437 | denotes | m−1 |
| T365 | 4213-4216 | http://purl.obolibrary.org/obo/CLO_0007448 | denotes | m−1 |
| T366 | 4213-4216 | http://purl.obolibrary.org/obo/CLO_0007449 | denotes | m−1 |
| T367 | 4213-4216 | http://purl.obolibrary.org/obo/CLO_0050175 | denotes | m−1 |
| T368 | 4213-4216 | http://purl.obolibrary.org/obo/CLO_0052399 | denotes | m−1 |
| T369 | 4217-4220 | http://purl.obolibrary.org/obo/CLO_0007052 | denotes | K−1 |
| T370 | 4245-4248 | http://purl.obolibrary.org/obo/CLO_0007437 | denotes | m−1 |
| T371 | 4245-4248 | http://purl.obolibrary.org/obo/CLO_0007448 | denotes | m−1 |
| T372 | 4245-4248 | http://purl.obolibrary.org/obo/CLO_0007449 | denotes | m−1 |
| T373 | 4245-4248 | http://purl.obolibrary.org/obo/CLO_0050175 | denotes | m−1 |
| T374 | 4245-4248 | http://purl.obolibrary.org/obo/CLO_0052399 | denotes | m−1 |
| T375 | 4249-4252 | http://purl.obolibrary.org/obo/CLO_0007052 | denotes | K−1 |
| T376 | 4442-4444 | http://purl.obolibrary.org/obo/PR_000005794 | denotes | CP |
| T377 | 4473-4474 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T378 | 4585-4587 | http://purl.obolibrary.org/obo/PR_000005794 | denotes | CP |
| T379 | 4605-4607 | http://purl.obolibrary.org/obo/CLO_0001562 | denotes | A2 |
| T380 | 4669-4672 | http://purl.obolibrary.org/obo/CLO_0007437 | denotes | m−1 |
| T381 | 4669-4672 | http://purl.obolibrary.org/obo/CLO_0007448 | denotes | m−1 |
| T382 | 4669-4672 | http://purl.obolibrary.org/obo/CLO_0007449 | denotes | m−1 |
| T383 | 4669-4672 | http://purl.obolibrary.org/obo/CLO_0050175 | denotes | m−1 |
| T384 | 4669-4672 | http://purl.obolibrary.org/obo/CLO_0052399 | denotes | m−1 |
| T385 | 4673-4676 | http://purl.obolibrary.org/obo/CLO_0007052 | denotes | K−1 |
| T386 | 4688-4691 | http://purl.obolibrary.org/obo/CLO_0007437 | denotes | m−1 |
| T387 | 4688-4691 | http://purl.obolibrary.org/obo/CLO_0007448 | denotes | m−1 |
| T388 | 4688-4691 | http://purl.obolibrary.org/obo/CLO_0007449 | denotes | m−1 |
| T389 | 4688-4691 | http://purl.obolibrary.org/obo/CLO_0050175 | denotes | m−1 |
| T390 | 4688-4691 | http://purl.obolibrary.org/obo/CLO_0052399 | denotes | m−1 |
| T391 | 4692-4695 | http://purl.obolibrary.org/obo/CLO_0007052 | denotes | K−1 |
| T392 | 4874-4876 | http://purl.obolibrary.org/obo/CLO_0001602 | denotes | A6 |
| T393 | 4874-4876 | http://purl.obolibrary.org/obo/CLO_0001603 | denotes | A6 |
| T394 | 4874-4876 | http://purl.obolibrary.org/obo/CLO_0050248 | denotes | A6 |
| T395 | 4874-4876 | http://purl.obolibrary.org/obo/CLO_0052463 | denotes | A6 |
| T396 | 4921-4923 | http://purl.obolibrary.org/obo/CLO_0001602 | denotes | A6 |
| T397 | 4921-4923 | http://purl.obolibrary.org/obo/CLO_0001603 | denotes | A6 |
| T398 | 4921-4923 | http://purl.obolibrary.org/obo/CLO_0050248 | denotes | A6 |
| T399 | 4921-4923 | http://purl.obolibrary.org/obo/CLO_0052463 | denotes | A6 |
| T400 | 5143-5146 | http://purl.obolibrary.org/obo/CLO_0051741 | denotes | C.1 |
| T401 | 5233-5234 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T402 | 5465-5467 | http://purl.obolibrary.org/obo/CLO_0001562 | denotes | A2 |
| T403 | 5531-5534 | http://purl.obolibrary.org/obo/CLO_0002105 | denotes | C.2 |
| T404 | 5531-5534 | http://purl.obolibrary.org/obo/CLO_0051742 | denotes | C.2 |
| T405 | 5571-5573 | http://purl.obolibrary.org/obo/CLO_0001562 | denotes | A2 |
| T406 | 5695-5698 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T407 | 5749-5751 | http://purl.obolibrary.org/obo/CLO_0001577 | denotes | A3 |
| T408 | 5808-5809 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T409 | 5872-5875 | http://purl.obolibrary.org/obo/CLO_0007052 | denotes | K−1 |
| T410 | 5925-5928 | http://purl.obolibrary.org/obo/CLO_0007052 | denotes | K−1 |
| T411 | 6048-6050 | http://purl.obolibrary.org/obo/CLO_0001577 | denotes | A3 |
| T412 | 6191-6195 | http://purl.obolibrary.org/obo/UBERON_0000025 | denotes | Tube |
| T413 | 6218-6222 | http://purl.obolibrary.org/obo/CLO_0053794 | denotes | 4 1 |
| T414 | 6223-6227 | http://purl.obolibrary.org/obo/UBERON_0000025 | denotes | Tube |
| T415 | 6245-6249 | http://purl.obolibrary.org/obo/CLO_0053794 | denotes | 4 1 |
| T416 | 6277-6281 | http://purl.obolibrary.org/obo/CLO_0053794 | denotes | 4 1 |
| T417 | 6304-6308 | http://purl.obolibrary.org/obo/CLO_0053794 | denotes | 4 1 |
| T418 | 6333-6339 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | Signal |
| T419 | 6496-6502 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signal |
| T420 | 6520-6526 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signal |
| T421 | 6608-6614 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signal |
| T422 | 6754-6761 | http://purl.obolibrary.org/obo/CLO_0053001 | denotes | 1 1 4 |
| T423 | 6791-6797 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signal |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T326 | 260-263 | Chemical | denotes | COC | http://purl.obolibrary.org/obo/CHEBI_53310 |
| T327 | 314-317 | Chemical | denotes | TCO | http://purl.obolibrary.org/obo/CHEBI_73156 |
| T33625 | 1538-1540 | Chemical | denotes | Au | http://purl.obolibrary.org/obo/CHEBI_29287 |
| T24785 | 1541-1545 | Chemical | denotes | gold | http://purl.obolibrary.org/obo/CHEBI_29287|http://purl.obolibrary.org/obo/CHEBI_30050 |
| T17487 | 1605-1608 | Chemical | denotes | CNC | http://purl.obolibrary.org/obo/CHEBI_48390 |
| T59723 | 1640-1653 | Chemical | denotes | cyclic olefin | http://purl.obolibrary.org/obo/CHEBI_33642 |
| T39124 | 1647-1653 | Chemical | denotes | olefin | http://purl.obolibrary.org/obo/CHEBI_32878|http://purl.obolibrary.org/obo/CHEBI_33641 |
| T5398 | 1654-1663 | Chemical | denotes | copolymer | http://purl.obolibrary.org/obo/CHEBI_53310|http://purl.obolibrary.org/obo/CHEBI_60804 |
| T77411 | 1696-1699 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
| T42976 | 1700-1721 | Chemical | denotes | deoxyribonucleic acid | http://purl.obolibrary.org/obo/CHEBI_16991 |
| T39672 | 1717-1721 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T42832 | 1744-1747 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
| T86992 | 1748-1751 | Chemical | denotes | H2O | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T76600 | 1752-1757 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T99250 | 1758-1761 | Chemical | denotes | HDA | http://purl.obolibrary.org/obo/CHEBI_17314 |
| T85004 | 1839-1842 | Chemical | denotes | MDA | http://purl.obolibrary.org/obo/CHEBI_566274 |
| T58905 | 1879-1881 | Chemical | denotes | Mo | http://purl.obolibrary.org/obo/CHEBI_28685 |
| T27858 | 1882-1892 | Chemical | denotes | molybdenum | http://purl.obolibrary.org/obo/CHEBI_28685 |
| T59668 | 1893-1895 | Chemical | denotes | N2 | http://purl.obolibrary.org/obo/CHEBI_17997 |
| T60784 | 1896-1904 | Chemical | denotes | nitrogen | http://purl.obolibrary.org/obo/CHEBI_25555 |
| T41200 | 1960-1964 | Chemical | denotes | PDMS | http://purl.obolibrary.org/obo/CHEBI_31498|http://purl.obolibrary.org/obo/CHEBI_61468 |
| T4197 | 1965-1985 | Chemical | denotes | polydimethylsiloxane | http://purl.obolibrary.org/obo/CHEBI_31498|http://purl.obolibrary.org/obo/CHEBI_48137|http://purl.obolibrary.org/obo/CHEBI_61466|http://purl.obolibrary.org/obo/CHEBI_61468 |
| T66807 | 1986-1989 | Chemical | denotes | PID | http://purl.obolibrary.org/obo/CHEBI_8066 |
| T29312 | 2023-2025 | Chemical | denotes | Pt | http://purl.obolibrary.org/obo/CHEBI_33364|http://purl.obolibrary.org/obo/CHEBI_75318 |
| T15969 | 2026-2034 | Chemical | denotes | platinum | http://purl.obolibrary.org/obo/CHEBI_33364|http://purl.obolibrary.org/obo/CHEBI_33400 |
| T33 | 2069-2085 | Chemical | denotes | ribonucleic acid | http://purl.obolibrary.org/obo/CHEBI_33697 |
| T34 | 2081-2085 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T35 | 2099-2107 | Chemical | denotes | electron | http://purl.obolibrary.org/obo/CHEBI_10545 |
| T46415 | 2141-2144 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
| T37 | 2244-2246 | Chemical | denotes | Tg | http://purl.obolibrary.org/obo/CHEBI_9516 |
| T61445 | 2409-2412 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
| T29550 | 2583-2588 | Chemical | denotes | Water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T40 | 2593-2596 | Chemical | denotes | H2O | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T41952 | 2661-2664 | Chemical | denotes | H2O | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T42 | 2735-2737 | Chemical | denotes | CP | http://purl.obolibrary.org/obo/CHEBI_3380|http://purl.obolibrary.org/obo/CHEBI_73461 |
| T89653 | 2738-2741 | Chemical | denotes | H2O | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T86499 | 2803-2806 | Chemical | denotes | H2O | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T57542 | 2862-2865 | Chemical | denotes | H2O | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T11533 | 2911-2913 | Chemical | denotes | CP | http://purl.obolibrary.org/obo/CHEBI_3380|http://purl.obolibrary.org/obo/CHEBI_73461 |
| T66816 | 2914-2917 | Chemical | denotes | H2O | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T7071 | 2943-2946 | Chemical | denotes | H2O | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T12493 | 3071-3074 | Chemical | denotes | H2O | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T51965 | 3105-3108 | Chemical | denotes | H2O | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T75402 | 3211-3213 | Chemical | denotes | CP | http://purl.obolibrary.org/obo/CHEBI_3380|http://purl.obolibrary.org/obo/CHEBI_73461 |
| T80136 | 3214-3217 | Chemical | denotes | H2O | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T58943 | 3318-3321 | Chemical | denotes | H2O | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T57 | 3413-3416 | Chemical | denotes | H2O | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T54057 | 3417-3419 | Chemical | denotes | CP | http://purl.obolibrary.org/obo/CHEBI_3380|http://purl.obolibrary.org/obo/CHEBI_73461 |
| T94258 | 3426-3429 | Chemical | denotes | H2O | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T24309 | 3471-3476 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T17347 | 3482-3485 | Chemical | denotes | H2O | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T33508 | 3492-3495 | Chemical | denotes | H2O | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T33600 | 4392-4394 | Chemical | denotes | MI | http://purl.obolibrary.org/obo/CHEBI_53620|http://purl.obolibrary.org/obo/CHEBI_74704 |
| T38514 | 4442-4444 | Chemical | denotes | CP | http://purl.obolibrary.org/obo/CHEBI_3380|http://purl.obolibrary.org/obo/CHEBI_73461 |
| T80519 | 4585-4587 | Chemical | denotes | CP | http://purl.obolibrary.org/obo/CHEBI_3380|http://purl.obolibrary.org/obo/CHEBI_73461 |
| T79571 | 5291-5293 | Chemical | denotes | Au | http://purl.obolibrary.org/obo/CHEBI_29287 |
| T71862 | 5330-5332 | Chemical | denotes | Pt | http://purl.obolibrary.org/obo/CHEBI_33364|http://purl.obolibrary.org/obo/CHEBI_75318 |
| T63251 | 5364-5366 | Chemical | denotes | Pt | http://purl.obolibrary.org/obo/CHEBI_33364|http://purl.obolibrary.org/obo/CHEBI_75318 |
| T8885 | 5376-5388 | Chemical | denotes | contaminants | http://purl.obolibrary.org/obo/CHEBI_143130 |
| T29877 | 5511-5513 | Chemical | denotes | Au | http://purl.obolibrary.org/obo/CHEBI_29287 |
| T73442 | 5817-5819 | Chemical | denotes | Au | http://purl.obolibrary.org/obo/CHEBI_29287 |
| T33570 | 5943-5946 | Chemical | denotes | MDA | http://purl.obolibrary.org/obo/CHEBI_566274 |
| T96396 | 5977-5984 | Chemical | denotes | mixture | http://purl.obolibrary.org/obo/CHEBI_60004 |
| T9097 | 6001-6004 | Chemical | denotes | MDA | http://purl.obolibrary.org/obo/CHEBI_566274 |
| T15044 | 6060-6063 | Chemical | denotes | MDA | http://purl.obolibrary.org/obo/CHEBI_566274 |
| T66557 | 6123-6126 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
| T37982 | 6138-6143 | Chemical | denotes | Water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T32368 | 6145-6147 | Chemical | denotes | EG | http://purl.obolibrary.org/obo/CHEBI_73505 |
| T16547 | 6201-6204 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
| T94653 | 6260-6263 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
| T14215 | 6549-6556 | Chemical | denotes | mixture | http://purl.obolibrary.org/obo/CHEBI_60004 |
| T66121 | 6668-6671 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
| T24099 | 6683-6688 | Chemical | denotes | Water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T80499 | 6690-6692 | Chemical | denotes | EG | http://purl.obolibrary.org/obo/CHEBI_73505 |
| T90409 | 6805-6812 | Chemical | denotes | mixture | http://purl.obolibrary.org/obo/CHEBI_60004 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T26 | 2409-2426 | http://purl.obolibrary.org/obo/GO_0006277 | denotes | DNA amplification |
| T27 | 5126-5131 | http://purl.obolibrary.org/obo/GO_0007568 | denotes | aging |
| T28 | 5343-5351 | http://purl.obolibrary.org/obo/GO_0007610 | denotes | behavior |
| T29 | 5536-5541 | http://purl.obolibrary.org/obo/GO_0007568 | denotes | Aging |
| T30 | 5689-5694 | http://purl.obolibrary.org/obo/GO_0007568 | denotes | aging |
| T31 | 5777-5782 | http://purl.obolibrary.org/obo/GO_0007568 | denotes | aging |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T381 | 0-15 | Sentence | denotes | Acknowledgments |
| T382 | 16-141 | Sentence | denotes | The authors would like to thank Brigitte Bruijns from Micronit Microtechnologies for her help during the brainstorm sessions. |
| T383 | 142-264 | Sentence | denotes | Jörg Strack from TOPAS Advanced Polymers and Thomas Wagenknecht from KUZ Leipzig are thanked for their information on COC. |
| T384 | 265-685 | Sentence | denotes | Pieter Post, Rob Dierink, and Sip Jan Boorsma of TCO (Technical Center for Education and Research of the University of Twente) are thanked for their work in the milling and laser cutting processes, Christian Bruinink for his assistance in the transparency measurements, Daniel Monteiro Cunha, M.Sc. for his assistance in the AFM measurements, and Nikki Stroot for her assistance with the initial amplification reactions. |
| T385 | 686-706 | Sentence | denotes | Sample Availability: |
| T386 | 707-773 | Sentence | denotes | Samples of the amplification chips are available from the authors. |
| T387 | 775-795 | Sentence | denotes | Author Contributions |
| T388 | 796-1234 | Sentence | denotes | Conceived and designed the experiments: H.-W.V., F.A.M., and R.S.; developed the measurement setup and software, and provided technical help: R.S.; developed the methodology: H.-W.V. and F.A.M.; performed the experiments: F.A.M.; visualized the results: H.-W.V. and F.A.M.; wrote the first draft of the paper: H.-W.V.; reviewed and edited the first draft of the paper: H.-W.V., F.A.M., R.S., R.W. and J.L.; supervised the project: H.-W.V. |
| T389 | 1235-1311 | Sentence | denotes | All authors have read and agreed to the published version of the manuscript. |
| T390 | 1313-1320 | Sentence | denotes | Funding |
| T391 | 1321-1370 | Sentence | denotes | This work is financed with institutional funding. |
| T392 | 1372-1393 | Sentence | denotes | Conflicts of Interest |
| T393 | 1394-1438 | Sentence | denotes | The authors declare no conflict of interest. |
| T394 | 1439-1452 | Sentence | denotes | Abbreviations |
| T395 | 1453-1537 | Sentence | denotes | The following abbreviations are used in this manuscript: AFM atomic force microscopy |
| T396 | 1538-1545 | Sentence | denotes | Au gold |
| T397 | 1546-1571 | Sentence | denotes | CAD computer-aided design |
| T398 | 1572-1604 | Sentence | denotes | CAM computer-aided manufacturing |
| T399 | 1605-1635 | Sentence | denotes | CNC computer numerical control |
| T400 | 1636-1663 | Sentence | denotes | COC cyclic olefin copolymer |
| T401 | 1664-1681 | Sentence | denotes | DC direct current |
| T402 | 1682-1695 | Sentence | denotes | DI de-ionized |
| T403 | 1696-1721 | Sentence | denotes | DNA deoxyribonucleic acid |
| T404 | 1722-1747 | Sentence | denotes | dsDNA double stranded DNA |
| T405 | 1748-1757 | Sentence | denotes | H2O water |
| T406 | 1758-1794 | Sentence | denotes | HDA helicase-dependent amplification |
| T407 | 1795-1838 | Sentence | denotes | LAMP loop-mediated isothermal amplification |
| T408 | 1839-1878 | Sentence | denotes | MDA multiple displacement amplification |
| T409 | 1879-1892 | Sentence | denotes | Mo molybdenum |
| T410 | 1893-1904 | Sentence | denotes | N2 nitrogen |
| T411 | 1905-1929 | Sentence | denotes | NTC non template control |
| T412 | 1930-1959 | Sentence | denotes | PCR polymerase chain reaction |
| T413 | 1960-1985 | Sentence | denotes | PDMS polydimethylsiloxane |
| T414 | 1986-2022 | Sentence | denotes | PID proportional-integral-derivative |
| T415 | 2023-2034 | Sentence | denotes | Pt platinum |
| T416 | 2035-2064 | Sentence | denotes | PVD physical vapor deposition |
| T417 | 2065-2085 | Sentence | denotes | RNA ribonucleic acid |
| T418 | 2086-2118 | Sentence | denotes | SEM scanning electron microscopy |
| T419 | 2119-2144 | Sentence | denotes | ssDNA single stranded DNA |
| T420 | 2145-2201 | Sentence | denotes | SDI Sexually Transmitted Diseases Diagnostics Initiative |
| T421 | 2202-2243 | Sentence | denotes | TCR temperature coefficient of resistance |
| T422 | 2244-2275 | Sentence | denotes | Tg glass transition temperature |
| T423 | 2276-2306 | Sentence | denotes | WGA whole genome amplification |
| T424 | 2307-2336 | Sentence | denotes | WHO World Health Organization |
| T425 | 2338-2349 | Sentence | denotes | Appendix A. |
| T426 | 2350-2372 | Sentence | denotes | Technical Drawing Chip |
| T427 | 2373-2432 | Sentence | denotes | Figure A1 Technical drawing of the DNA amplification chip. |
| T428 | 2433-2458 | Sentence | denotes | All dimensions are in mm. |
| T429 | 2459-2495 | Sentence | denotes | The total chip size is 3 mm by 3 mm. |
| T430 | 2497-2508 | Sentence | denotes | Appendix B. |
| T431 | 2509-2567 | Sentence | denotes | Equations and Values Used in the COMSOL Multiphysics Study |
| T432 | 2569-2582 | Sentence | denotes | Appendix B.1. |
| T433 | 2583-2588 | Sentence | denotes | Water |
| T434 | 2589-2849 | Sentence | denotes | For H2O, the build-in temperature-dependent equations for the density (ρH2O, see equations in Equation (A1)), heat capacity at constant pressure (CP,H2O, see equations in Equation (A2)), and thermal conductivity (κH2O, see equations in Equation (A3)) are used. |
| T435 | 2850-3054 | Sentence | denotes | The ratio (γH2O) of the specific heats at constant pressure (CP,H2O) and constant volume (CV,H2O) is calculated manually according to the table from the Engineering Toolbox website [81] and Equation (A4). |
| T436 | 3055-3429 | Sentence | denotes | The values for γH2O are listed in Table A1. (A1) ρH2O(T)=972.7584+0.2084T−4×10−4T2for273≤T<283345.28+5.749816T−0.0157244T2+1.264375×10−5T3for283≤T<373 (A2) CP,H2O(T)=12010.1471−80.4072879T+0.309866854T2for273.15≤T<553.75−5.38186884×10−4T3+3.62536437×10−7T4 (A3) κH2O(T)=−0.869083936+0.00894880345T−1.58366345×10−5T2for273.15≤T<553.75+7.97543259×10−9T3 (A4) γH2O=CP,H2OCV,H2O |
| T437 | 3430-3477 | Sentence | denotes | Table A1 The ratio of specific heats of water. |
| T438 | 3478-3495 | Sentence | denotes | T γH2O T γH2O |
| T439 | 3496-3514 | Sentence | denotes | [K] [-] [K] [-] |
| T440 | 3515-3555 | Sentence | denotes | 273.16 1.000592782 393.15 1.157465496 |
| T441 | 3556-3596 | Sentence | denotes | 283.15 1.001073729 413.15 1.199809492 |
| T442 | 3597-3637 | Sentence | denotes | 293.15 1.006591292 433.15 1.246234334 |
| T443 | 3638-3678 | Sentence | denotes | 298.15 1.010560913 453.15 1.297534537 |
| T444 | 3679-3719 | Sentence | denotes | 303.15 1.015203400 473.15 1.355013713 |
| T445 | 3720-3760 | Sentence | denotes | 313.15 1.025996023 493.15 1.420794975 |
| T446 | 3761-3801 | Sentence | denotes | 323.15 1.038520763 513.15 1.498241758 |
| T447 | 3802-3842 | Sentence | denotes | 333.15 1.052405261 533.15 1.592792563 |
| T448 | 3843-3883 | Sentence | denotes | 343.15 1.067512483 553.15 1.714447794 |
| T449 | 3884-3924 | Sentence | denotes | 353.15 1.083658241 573.15 1.883524402 |
| T450 | 3925-3965 | Sentence | denotes | 363.15 1.100748613 593.15 2.148448797 |
| T451 | 3966-4006 | Sentence | denotes | 373.15 1.118756966 613.15 2.666580033 |
| T452 | 4007-4047 | Sentence | denotes | 383.15 1.137648990 633.15 4.550527720 |
| T453 | 4049-4062 | Sentence | denotes | Appendix B.2. |
| T454 | 4063-4086 | Sentence | denotes | Cyclic Olefin Copolymer |
| T455 | 4087-4401 | Sentence | denotes | Values for the density (ρCOC = 1020 kg m−3), specific heat (cCOC, see Table A2), and thermal conductivity (κCOC,23°C = 0.17 W m−1 K−1 and κCOC,320°C = 0.24 W m−1 K−1, linear fit in between these point) of TOPAS 6017 COC are obtained via TOPAS Advanced Polymers (TOPAS Advanced Polymers, Farmington Hills, MI, USA). |
| T456 | 4402-4598 | Sentence | denotes | The heat capacity at constant pressure (CP,COC) is calculated assuming a homogeneous body of mass m, via Equation (A5), where COMSOL interpolated linearly in between the points. (A5) CP,COC=cCOC×m |
| T457 | 4599-4645 | Sentence | denotes | Table A2 The specific heat of TOPAS 6017 COC. |
| T458 | 4646-4659 | Sentence | denotes | T c T c |
| T459 | 4660-4696 | Sentence | denotes | [°C] [W m−1 K−1] [°C] [W m−1 K−1] |
| T460 | 4697-4716 | Sentence | denotes | 30 1333 180 2298 |
| T461 | 4717-4736 | Sentence | denotes | 70 1538 210 2412 |
| T462 | 4737-4757 | Sentence | denotes | 110 1754 250 2539 |
| T463 | 4758-4778 | Sentence | denotes | 150 1968 290 2645 |
| T464 | 4779-4936 | Sentence | denotes | 160 2047 330 2758 Convective heat loss to the air is also taken into account with Equation (A6), which is often used in simulations [56]. (A6) h=10Wm−2K−1 |
| T465 | 4938-4949 | Sentence | denotes | Appendix C. |
| T466 | 4950-4966 | Sentence | denotes | TCR Measurements |
| T467 | 4967-5132 | Sentence | denotes | The two subsections below show two effects on the TCR measurements, i.e., the effect of thermal annealing during the first temperature cycle and the effect of aging. |
| T468 | 5134-5147 | Sentence | denotes | Appendix C.1. |
| T469 | 5148-5165 | Sentence | denotes | Thermal Annealing |
| T470 | 5166-5254 | Sentence | denotes | The graph below is an example of the measured thermal annealing of a metal layer on COC. |
| T471 | 5255-5352 | Sentence | denotes | Here, only the graph for evaporated Au is shown, but all except evaporated Pt show this behavior. |
| T472 | 5353-5408 | Sentence | denotes | Evaporated Pt had some contaminants in the metal track. |
| T473 | 5409-5457 | Sentence | denotes | This is most probably caused by the shadow mask. |
| T474 | 5458-5520 | Sentence | denotes | Figure A2 Thermal annealing of an evaporated 100 nm Au layer. |
| T475 | 5522-5535 | Sentence | denotes | Appendix C.2. |
| T476 | 5536-5541 | Sentence | denotes | Aging |
| T477 | 5542-5650 | Sentence | denotes | The layer analyzed in Figure A2 is stored for two weeks in ambient conditions and the TCR is analyzed again. |
| T478 | 5651-5741 | Sentence | denotes | From the graph it is visible that the aging has some effect on the TCR of the metal layer. |
| T479 | 5742-5826 | Sentence | denotes | Figure A3 The effect of two weeks aging in ambient conditions on a 100 nm Au layer. |
| T480 | 5827-5929 | Sentence | denotes | The TCR of the as deposited layer is 0.00161 K−1 and the TCR of the two week old layer is 0.00224 K−1. |
| T481 | 5931-5942 | Sentence | denotes | Appendix D. |
| T482 | 5943-5963 | Sentence | denotes | MDA Reaction Mixture |
| T483 | 5964-6041 | Sentence | denotes | The reaction mixture for the on-chip MDA reaction consisted of the following. |
| T484 | 6042-6082 | Sentence | denotes | Table A3 On-chip MDA reaction mixtures. |
| T485 | 6083-6155 | Sentence | denotes | Sample Reaction Buffer Sample Buffer DNA MilliQ DI Water EG Enzyme |
| T486 | 6156-6190 | Sentence | denotes | [μL] [μL] [μL] [μL] [μL] [μL] |
| T487 | 6191-6222 | Sentence | denotes | Tube with DNA 9 9 1 - 4 1 |
| T488 | 6223-6249 | Sentence | denotes | Tube NTC 9 9 - 1 4 1 |
| T489 | 6250-6281 | Sentence | denotes | Chip with DNA 9 9 1 - 4 1 |
| T490 | 6282-6308 | Sentence | denotes | Chip NTC 9 9 - 1 4 1 |
| T491 | 6310-6321 | Sentence | denotes | Appendix E. |
| T492 | 6322-6365 | Sentence | denotes | Background Signal Fluorescence Measurements |
| T493 | 6366-6503 | Sentence | denotes | All fluorescence measurements in the Horiba Scientific FluoroMax+ spectrofluorometer are normalized by subtracting the background signal. |
| T494 | 6504-6569 | Sentence | denotes | This background signal is measured using the mixture in Table A4. |
| T495 | 6570-6627 | Sentence | denotes | Table A4 Mixture used for background signal measurement. |
| T496 | 6628-6700 | Sentence | denotes | Sample Reaction Buffer Sample Buffer DNA MilliQ DI Water EG Enzyme |
| T497 | 6701-6735 | Sentence | denotes | [μL] [μL] [μL] [μL] [μL] [μL] |
| T498 | 6736-6764 | Sentence | denotes | Background 9 9 1 1 4 - |
| T499 | 6765-6825 | Sentence | denotes | Figure A4 The background signal of the mixture in Table A4. |