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PMC:7143804 / 27319-30599 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
195 524-527 Chemical denotes H2O
196 697-700 Chemical denotes COC
197 705-708 Chemical denotes H2O
198 891-894 Chemical denotes COC
199 899-902 Chemical denotes H2O
200 1097-1100 Chemical denotes H2O
201 1105-1108 Chemical denotes COC
204 3059-3064 Chemical denotes metal MESH:D008670
205 2913-2921 Disease denotes stresses MESH:D000079225

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T189 1204-1205 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T190 1395-1396 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T191 1493-1494 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T192 1634-1635 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T193 1804-1805 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T194 1835-1836 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T195 1849-1850 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T196 1871-1872 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T197 1925-1926 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T198 2252-2254 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T199 2285-2286 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T200 2331-2332 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T201 2417-2418 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T202 2507-2513 http://purl.obolibrary.org/obo/OBI_0000968 denotes device
T203 2825-2827 http://purl.obolibrary.org/obo/CLO_0007815 denotes Mo
T204 3057-3058 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T205 3092-3095 http://purl.obolibrary.org/obo/CLO_0051582 denotes has

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T180 524-527 Chemical denotes H2O http://purl.obolibrary.org/obo/CHEBI_15377
T181 532-535 Chemical denotes COC http://purl.obolibrary.org/obo/CHEBI_53310
T182 697-700 Chemical denotes COC http://purl.obolibrary.org/obo/CHEBI_53310
T183 705-708 Chemical denotes H2O http://purl.obolibrary.org/obo/CHEBI_15377
T184 891-894 Chemical denotes COC http://purl.obolibrary.org/obo/CHEBI_53310
T185 899-902 Chemical denotes H2O http://purl.obolibrary.org/obo/CHEBI_15377
T186 1097-1100 Chemical denotes H2O http://purl.obolibrary.org/obo/CHEBI_15377
T187 1105-1108 Chemical denotes COC http://purl.obolibrary.org/obo/CHEBI_53310
T188 1328-1335 Chemical denotes mixture http://purl.obolibrary.org/obo/CHEBI_60004
T189 2217-2220 Chemical denotes MDA http://purl.obolibrary.org/obo/CHEBI_566274
T190 2727-2734 Chemical denotes mixture http://purl.obolibrary.org/obo/CHEBI_60004
T191 2825-2827 Chemical denotes Mo http://purl.obolibrary.org/obo/CHEBI_28685
T192 3014-3017 Chemical denotes COC http://purl.obolibrary.org/obo/CHEBI_53310

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T209 0-4 Sentence denotes 3.1.
T210 5-43 Sentence denotes COMSOL MultiPhysics Simulation Results
T211 44-141 Sentence denotes In Figure 5, the results of heat transfer simulations of two different heater spacings are shown.
T212 142-266 Sentence denotes The heater width for both geometries is 0.3 mm, while the heater spacing in Figure 5b,c are 0.3 mm and 2.0 mm, respectively.
T213 267-394 Sentence denotes In Figure 6a–d, tables with the results of the full parametric sweep for different heater widths and heater spacings are shown.
T214 395-581 Sentence denotes Figure 6a shows the temperature deviation between the highest and lowest temperature at the top of the chamber, i.e., the second H2O and COC interface (ΔTtopofchamber=Ttop,max−Ttop,min).
T215 582-759 Sentence denotes Figure 6b shows the deviation between the highest and lowest temperature inside the chamber, i.e., between the two COC and H2O interfaces (ΔTacrosschamber=Tbottom,max−Ttop,min).
T216 760-951 Sentence denotes Figure 6c shows the temperature deviation between the highest and lowest temperature at the bottom of the chamber, i.e., the first COC and H2O interface (ΔTbottomofchamber=Tbot,max−Tbot,min).
T217 952-1158 Sentence denotes Figure 6d shows the deviation between the set heater temperature of 30 °C and the lowest temperature at the top of the chamber, i.e., the second H2O and COC interface (ΔTdeviationfromsetT=Theater−Ttop,min).
T218 1159-1336 Sentence denotes As can be seen from the results in Figure 6, a combination of small heater widths and heater spacings will result in smaller temperature differences inside the reaction mixture.
T219 1337-1451 Sentence denotes This is evident as smaller heater spacings will result in a better coverage of the heated area by heater material.
T220 1452-1606 Sentence denotes The smaller heater widths will result in a smaller heater cross-sectional area, and thus can be operated at lower powers, as is evident from Equation (1).
T221 1607-1760 Sentence denotes Resulting in the fact that a densely packed meander structure with small heater widths and small heater spacings can dissipate more heat into the system.
T222 1761-1924 Sentence denotes Based on these results and its simplicity, a meandering heater pattern of a heater with a width of 0.3 mm and a spacing of 0.3 mm in between the lines is designed.
T223 1925-2126 Sentence denotes A side note on the chosen heater width and heater spacing is that according to the simulations, the temperature differences within the chamber are less than ±0.3 °C for the most unfavorable dimensions.
T224 2127-2259 Sentence denotes This temperature difference is still well-accepted in the temperature window in which the MDA reaction takes place (25 °C to 35 °C).
T225 2260-2399 Sentence denotes However, as pointed out, a smaller cross-sectional area will result in a lower power consumption and therefore these dimensions are chosen.
T226 2400-2519 Sentence denotes It is known that a meandering heater structure does not give the optimal temperature distribution over the device [26].
T227 2520-2735 Sentence denotes Therefore, the heater lines are longer than the width of the reaction chamber, and thus also covering the bulk material outside the chamber in order to improve the temperature uniformity inside the reaction mixture.
T228 2736-2871 Sentence denotes The heater pattern is divided over two shadow masks to minimize the length of the narrow Mo tracks in between the meandering structure.
T229 2872-2922 Sentence denotes This prevents curvature due to intrinsic stresses.
T230 2923-3018 Sentence denotes See Figure 7 for the outlines of both shadow masks, together with the resulting pattern on COC.
T231 3019-3117 Sentence denotes The use of two shadow masks will give a metal track in which small parts has the double thickness.
T232 3118-3154 Sentence denotes Here, the temperature will be lower.
T233 3155-3280 Sentence denotes The system is designed such that these thicker parts are outside the reaction chamber and temperature control chamber region.