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PMC:7143804 / 13517-15854 JSONTXT

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LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 748-751 https://glytoucan.org/Structures/Glycans/G00063MO denotes CAD

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T33 476-478 Body_part denotes V2 http://purl.org/sig/ont/fma/fma13443|http://purl.org/sig/ont/fma/fma68615
T35 479-482 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T36 918-921 Body_part denotes CAM http://purl.org/sig/ont/fma/fma67214
T37 1333-1342 Body_part denotes trapezoid http://purl.org/sig/ont/fma/fma23724
T38 1453-1463 Body_part denotes trapezoids http://purl.org/sig/ont/fma/fma23724
T39 2271-2273 Body_part denotes A1 http://purl.org/sig/ont/fma/fma66592
T40 2278-2286 Body_part denotes Appendix http://purl.org/sig/ont/fma/fma14542

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T20 748-751 Disease denotes CAD http://purl.obolibrary.org/obo/MONDO_0005010|http://purl.obolibrary.org/obo/MONDO_0018922
T22 1030-1033 Disease denotes CNC http://purl.obolibrary.org/obo/MONDO_0015285|http://purl.obolibrary.org/obo/MONDO_0019134

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T92 59-60 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T93 82-83 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T94 123-127 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2, a
T95 315-317 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T96 720-724 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T97 1000-1001 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T98 1030-1033 http://purl.obolibrary.org/obo/UBERON_0003099 denotes CNC
T99 1269-1270 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T100 1691-1692 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T101 1901-1902 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T102 2015-2016 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T103 2104-2105 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T104 2287-2288 http://purl.obolibrary.org/obo/CLO_0001020 denotes A

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T82 235-248 Chemical denotes food coloring http://purl.obolibrary.org/obo/CHEBI_77182
T83 249-252 Chemical denotes dye http://purl.obolibrary.org/obo/CHEBI_37958
T84 479-482 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T85 502-504 Chemical denotes GE http://purl.obolibrary.org/obo/CHEBI_73801
T86 586-589 Chemical denotes dye http://purl.obolibrary.org/obo/CHEBI_37958
T87 590-598 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T88 1030-1033 Chemical denotes CNC http://purl.obolibrary.org/obo/CHEBI_48390
T89 1609-1616 Chemical denotes mixture http://purl.obolibrary.org/obo/CHEBI_60004
T90 2059-2066 Chemical denotes mixture http://purl.obolibrary.org/obo/CHEBI_60004

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T7 479-496 http://purl.obolibrary.org/obo/GO_0006277 denotes DNA amplification

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T114 0-112 Sentence denotes The microfluidic structure consists of two chambers, i.e., a reaction chamber and a temperature monitor chamber.
T115 113-164 Sentence denotes In Figure 2, a close-up of the final chip is shown.
T116 165-253 Sentence denotes For clarity reasons, the two microfluidic structures are colored with food coloring dye.
T117 254-702 Sentence denotes The reaction chamber is based on the work of Bruijns et al. [36] and its dimensions are chosen in such way that the internal volume of the reaction chamber is the same as the reaction volume of the used Illustra GenomiPhi V2 DNA amplification kit (GE Healthcare Life Sciences, Eindhoven, The Netherlands) together with the EvaGreen dye solution (Biotium, Fremont, CA, USA), while maintaining an as low as possible surface-area-to-volume ratio [44].
T118 703-1048 Sentence denotes Using SolidWorks 2018 computer-aided design (CAD) software (Dassault Systemes, Vélizy-Villacoublay, France), the 3D image of the chip is drawn and with the use of the AutoDesk HSMWorks computer-aided manufacturing (CAM) plug-in (Autodesk Inc., San Rafael, CA, USA), this image is transferred into a computer numerical control (CNC) milling code.
T119 1049-1137 Sentence denotes The total chip size is 3 cm by 3 cm and contains an inlet and outlet of 1.5 mm diameter.
T120 1138-1235 Sentence denotes The inlet and outlet are of such size that the reaction chamber can be filled using pipette tips.
T121 1236-1328 Sentence denotes In between the inlet and outlet, a rectangular reaction chamber of 10 mm by 3 mm is located.
T122 1329-1430 Sentence denotes Two trapezoid structures are placed in the tapered channels between the inlet/outlet and the chamber.
T123 1431-1475 Sentence denotes The function of these trapezoids is twofold:
T124 1476-1636 Sentence denotes First, they minimize the dead volume between the inlet/outlet and the reaction chamber, locating as much as possible of the reaction mixture inside the chamber.
T125 1637-1690 Sentence denotes Second, they provide support for the chamber closure.
T126 1691-1848 Sentence denotes A stadium-shaped channel of 1.5 mm wide and 1.0 mm deep is located next to the reaction chamber, in such way that this channel is also covered by the heater.
T127 1849-1900 Sentence denotes This channel serves as temperature monitor chamber.
T128 1901-2004 Sentence denotes A thermocouple is inserted in this channel for real-time monitoring of the temperature inside the chip.
T129 2005-2099 Sentence denotes This way, a more accurate temperature of the reaction mixture inside the chip can be obtained.
T130 2100-2170 Sentence denotes Via a feedback loop, the input potential can be changed when required.
T131 2171-2260 Sentence denotes In Figure 3, the SolidWorks design of the chamber-based chip with both chambers is shown.
T132 2261-2337 Sentence denotes In Figure A1, in Appendix A, the technical drawing of the chip can be found.