PMC:7143804 / 12767-13453
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T32 | 585-588 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T88 | 128-129 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T89 | 294-297 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T90 | 533-534 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T91 | 678-685 | http://purl.obolibrary.org/obo/OBI_0000968 | denotes | devices |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T78 | 12-15 | Chemical | denotes | MDA | http://purl.obolibrary.org/obo/CHEBI_566274 |
T79 | 130-136 | Chemical | denotes | buffer | http://purl.obolibrary.org/obo/CHEBI_35225 |
T80 | 585-588 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
T81 | 601-604 | Chemical | denotes | MDA | http://purl.obolibrary.org/obo/CHEBI_566274 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T106 | 0-244 | Sentence | denotes | Even though MDA is considered an isothermal process, prior to the reaction and to the addition of most reactants, the dsDNA and a buffer are heated up to 95 °C to denature the dsDNA to ssDNA and to give hexamers the initial access to the ssDNA. |
T107 | 245-325 | Sentence | denotes | After the amplification reaction, the polymerase has to be inactivated at 65 °C. |
T108 | 326-469 | Sentence | denotes | However, this does not require fast temperature changes, as would be the case with, for example, the temperature cycling in PCR amplifications. |
T109 | 470-686 | Sentence | denotes | This, together with the robustness of the amplification (it is a self-limiting reaction that amplifies all present DNA [50]) makes MDA perfectly suitable as proof-of-principle amplification reaction for such devices. |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32106462-16786504-69893313 | 590-592 | 16786504 | denotes | 50 |