PMC:7128678 / 8439-9131
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
276 | 267-280 | Species | denotes | coronaviruses | Tax:11118 |
283 | 95-106 | Chemical | denotes | carboxylate | |
284 | 116-122 | Chemical | denotes | Neu5Ac | |
285 | 310-344 | Chemical | denotes | 9-O-acetyl-N-acetylneuraminic acid | MESH:C025676 |
286 | 477-488 | Chemical | denotes | sialic acid | MESH:D019158 |
287 | 616-627 | Chemical | denotes | carboxylate | |
288 | 641-652 | Chemical | denotes | sialic acid | MESH:D019158 |
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T190 | 116-122 | PR:000002082 | denotes | Neu5Ac |
T191 | 142-150 | CHEBI:36916;CHEBI:36916 | denotes | cationic |
T192 | 222-229 | GO:0032991 | denotes | complex |
T193 | 267-280 | NCBITaxon:11118 | denotes | coronaviruses |
T194 | 310-311 | CHEBI:16066;CHEBI:16066 | denotes | 9 |
T195 | 314-320 | CHEBI:40574;CHEBI:40574 | denotes | acetyl |
T196 | 321-344 | CHEBI:17012;CHEBI:17012 | denotes | N-acetylneuraminic acid |
T197 | 477-488 | CHEBI:26667;CHEBI:26667 | denotes | sialic acid |
T198 | 628-633 | CHEBI:24433;CHEBI:24433 | denotes | group |
T199 | 641-652 | CHEBI:26667;CHEBI:26667 | denotes | sialic acid |
T200 | 673-687 | CHEBI:64766;CHEBI:64766 | denotes | cationic group |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T41 | 321-344 | Body_part | denotes | N-acetylneuraminic acid | http://purl.org/sig/ont/fma/fma82788 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T54 | 13-14 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T55 | 15-16 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
T56 | 377-378 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T57 | 490-491 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T58 | 545-548 | http://purl.obolibrary.org/obo/CLO_0002755 | denotes | d–f |
T59 | 585-587 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 45 |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T134 | 107-112 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
T135 | 116-122 | Chemical | denotes | Neu5Ac | http://purl.obolibrary.org/obo/CHEBI_17012|http://purl.obolibrary.org/obo/CHEBI_75133 |
T137 | 314-320 | Chemical | denotes | acetyl | http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887 |
T139 | 321-344 | Chemical | denotes | N-acetylneuraminic acid | http://purl.obolibrary.org/obo/CHEBI_17012 |
T140 | 340-344 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T141 | 477-488 | Chemical | denotes | sialic acid | http://purl.obolibrary.org/obo/CHEBI_26667 |
T142 | 484-488 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T143 | 628-633 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
T144 | 641-652 | Chemical | denotes | sialic acid | http://purl.obolibrary.org/obo/CHEBI_26667 |
T145 | 648-652 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T146 | 673-687 | Chemical | denotes | cationic group | http://purl.obolibrary.org/obo/CHEBI_64766 |
T147 | 682-687 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T66 | 19-187 | Sentence | denotes | The interaction was driven by the positioning of the negative charge of the carboxylate group of Neu5Ac and one of the two cationic charges of CLQ (pKa 10.2) Fig. 2(c). |
T67 | 188-263 | Sentence | denotes | The energy of interaction of this complex was estimated to be -47 kJ.mol−1. |
T68 | 264-489 | Sentence | denotes | As coronaviruses preferentially interact with 9-O-acetyl-N-acetylneuraminic acid (9-O-SIA) [10], this study used a similar molecular modelling approach to assess whether CLQ could also interact with this specific sialic acid. |
T69 | 490-597 | Sentence | denotes | A good fit between CLQ and 9-O-SIA was obtained Fig. 2(d–f), with an energy of interaction of -45 kJ.mol−1. |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32251731-23873408-48149952 | 356-358 | 23873408 | denotes | 10 |
T46400 | 356-358 | 23873408 | denotes | 10 |