PMC:7128678 / 5984-6517 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"164","span":{"begin":0,"end":23},"obj":"Chemical"},{"id":"165","span":{"begin":25,"end":31},"obj":"Chemical"},{"id":"166","span":{"begin":76,"end":110},"obj":"Chemical"},{"id":"167","span":{"begin":112,"end":119},"obj":"Chemical"},{"id":"168","span":{"begin":167,"end":224},"obj":"Chemical"},{"id":"169","span":{"begin":299,"end":305},"obj":"Chemical"},{"id":"170","span":{"begin":309,"end":377},"obj":"Chemical"},{"id":"171","span":{"begin":379,"end":385},"obj":"Chemical"},{"id":"172","span":{"begin":453,"end":459},"obj":"Chemical"},{"id":"173","span":{"begin":498,"end":503},"obj":"Chemical"}],"attributes":[{"id":"A164","pred":"tao:has_database_id","subj":"164","obj":"MESH:D019158"},{"id":"A166","pred":"tao:has_database_id","subj":"166","obj":"MESH:C025676"},{"id":"A173","pred":"tao:has_database_id","subj":"173","obj":"MESH:D014867"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"N-acetylneuraminic acid (Neu5Ac) was generated with the Hyperchem database. 9-O-acetyl-N-acetylneuraminic acid (9-O-SIA) was retrieved from pdb file 6Q06 [18]. CLQ is N-(7-chloroquinolin-4-yl)-N,N-diéthyl-pentane-1,4-diamine. Its three-dimensioanl structure was retrieved from pdb file # 4V2O [19]. CLQ-OH is (RS)-2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol. CLQ-OH was generated by hydroxylation of CLQ with Hyperchem. Both CLQ and CLQ-OH were energy-minimized and merged with water molecules as described below."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T128","span":{"begin":0,"end":23},"obj":"CHEBI:17012;CHEBI:17012"},{"id":"T129","span":{"begin":25,"end":31},"obj":"PR:000002082"},{"id":"T130","span":{"begin":76,"end":77},"obj":"CHEBI:17865;CHEBI:17865"},{"id":"T131","span":{"begin":77,"end":80},"obj":"CHEBI:16066;CHEBI:16066"},{"id":"T132","span":{"begin":80,"end":86},"obj":"CHEBI:40574;CHEBI:40574"},{"id":"T133","span":{"begin":87,"end":110},"obj":"CHEBI:17012;CHEBI:17012"},{"id":"T134","span":{"begin":170,"end":171},"obj":"CHEBI:17759;CHEBI:17759"},{"id":"T135","span":{"begin":172,"end":186},"obj":"CHEBI:52029;CHEBI:52029"},{"id":"T136","span":{"begin":187,"end":188},"obj":"CHEBI:75508;CHEBI:75508"},{"id":"T137","span":{"begin":205,"end":212},"obj":"CHEBI:37830;CHEBI:37830"},{"id":"T138","span":{"begin":213,"end":215},"obj":"CHEBI:52029;CHEBI:52029"},{"id":"T139","span":{"begin":215,"end":216},"obj":"CHEBI:53233;CHEBI:53233"},{"id":"T140","span":{"begin":217,"end":224},"obj":"CHEBI:23666;CHEBI:23666"},{"id":"T141","span":{"begin":314,"end":356},"obj":"CHEBI:5801;CHEBI:5801"},{"id":"T142","span":{"begin":358,"end":363},"obj":"CHEBI:5801;CHEBI:5801"},{"id":"T143","span":{"begin":370,"end":377},"obj":"CHEBI:5801;CHEBI:5801"},{"id":"T144","span":{"begin":498,"end":503},"obj":"CHEBI:15377;CHEBI:15377"},{"id":"T145","span":{"begin":504,"end":513},"obj":"CHEBI:36357;CHEBI:36357"}],"text":"N-acetylneuraminic acid (Neu5Ac) was generated with the Hyperchem database. 9-O-acetyl-N-acetylneuraminic acid (9-O-SIA) was retrieved from pdb file 6Q06 [18]. CLQ is N-(7-chloroquinolin-4-yl)-N,N-diéthyl-pentane-1,4-diamine. Its three-dimensioanl structure was retrieved from pdb file # 4V2O [19]. CLQ-OH is (RS)-2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol. CLQ-OH was generated by hydroxylation of CLQ with Hyperchem. Both CLQ and CLQ-OH were energy-minimized and merged with water molecules as described below."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T35","span":{"begin":0,"end":23},"obj":"Body_part"},{"id":"T36","span":{"begin":87,"end":110},"obj":"Body_part"}],"attributes":[{"id":"A35","pred":"fma_id","subj":"T35","obj":"http://purl.org/sig/ont/fma/fma82788"},{"id":"A36","pred":"fma_id","subj":"T36","obj":"http://purl.org/sig/ont/fma/fma82788"}],"text":"N-acetylneuraminic acid (Neu5Ac) was generated with the Hyperchem database. 9-O-acetyl-N-acetylneuraminic acid (9-O-SIA) was retrieved from pdb file 6Q06 [18]. CLQ is N-(7-chloroquinolin-4-yl)-N,N-diéthyl-pentane-1,4-diamine. Its three-dimensioanl structure was retrieved from pdb file # 4V2O [19]. CLQ-OH is (RS)-2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol. CLQ-OH was generated by hydroxylation of CLQ with Hyperchem. Both CLQ and CLQ-OH were energy-minimized and merged with water molecules as described below."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T26","span":{"begin":310,"end":312},"obj":"Disease"}],"attributes":[{"id":"A26","pred":"mondo_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/MONDO_0010725"}],"text":"N-acetylneuraminic acid (Neu5Ac) was generated with the Hyperchem database. 9-O-acetyl-N-acetylneuraminic acid (9-O-SIA) was retrieved from pdb file 6Q06 [18]. CLQ is N-(7-chloroquinolin-4-yl)-N,N-diéthyl-pentane-1,4-diamine. Its three-dimensioanl structure was retrieved from pdb file # 4V2O [19]. CLQ-OH is (RS)-2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol. CLQ-OH was generated by hydroxylation of CLQ with Hyperchem. Both CLQ and CLQ-OH were energy-minimized and merged with water molecules as described below."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T37","span":{"begin":155,"end":157},"obj":"http://purl.obolibrary.org/obo/CLO_0050510"},{"id":"T38","span":{"begin":310,"end":312},"obj":"http://purl.obolibrary.org/obo/CLO_0008882"}],"text":"N-acetylneuraminic acid (Neu5Ac) was generated with the Hyperchem database. 9-O-acetyl-N-acetylneuraminic acid (9-O-SIA) was retrieved from pdb file 6Q06 [18]. CLQ is N-(7-chloroquinolin-4-yl)-N,N-diéthyl-pentane-1,4-diamine. Its three-dimensioanl structure was retrieved from pdb file # 4V2O [19]. CLQ-OH is (RS)-2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol. CLQ-OH was generated by hydroxylation of CLQ with Hyperchem. Both CLQ and CLQ-OH were energy-minimized and merged with water molecules as described below."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T69","span":{"begin":0,"end":23},"obj":"Chemical"},{"id":"T70","span":{"begin":19,"end":23},"obj":"Chemical"},{"id":"T71","span":{"begin":25,"end":31},"obj":"Chemical"},{"id":"T73","span":{"begin":80,"end":86},"obj":"Chemical"},{"id":"T75","span":{"begin":87,"end":110},"obj":"Chemical"},{"id":"T76","span":{"begin":106,"end":110},"obj":"Chemical"},{"id":"T77","span":{"begin":205,"end":212},"obj":"Chemical"},{"id":"T78","span":{"begin":217,"end":224},"obj":"Chemical"},{"id":"T80","span":{"begin":310,"end":312},"obj":"Chemical"},{"id":"T81","span":{"begin":344,"end":349},"obj":"Chemical"},{"id":"T82","span":{"begin":350,"end":356},"obj":"Chemical"},{"id":"T83","span":{"begin":358,"end":363},"obj":"Chemical"},{"id":"T85","span":{"begin":364,"end":369},"obj":"Chemical"},{"id":"T86","span":{"begin":370,"end":377},"obj":"Chemical"},{"id":"T87","span":{"begin":498,"end":503},"obj":"Chemical"},{"id":"T88","span":{"begin":504,"end":513},"obj":"Chemical"}],"attributes":[{"id":"A69","pred":"chebi_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/CHEBI_17012"},{"id":"A70","pred":"chebi_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A71","pred":"chebi_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/CHEBI_17012"},{"id":"A72","pred":"chebi_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/CHEBI_75133"},{"id":"A73","pred":"chebi_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/CHEBI_40574"},{"id":"A74","pred":"chebi_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/CHEBI_46887"},{"id":"A75","pred":"chebi_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/CHEBI_17012"},{"id":"A76","pred":"chebi_id","subj":"T76","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A77","pred":"chebi_id","subj":"T77","obj":"http://purl.obolibrary.org/obo/CHEBI_37830"},{"id":"A78","pred":"chebi_id","subj":"T78","obj":"http://purl.obolibrary.org/obo/CHEBI_15571"},{"id":"A79","pred":"chebi_id","subj":"T78","obj":"http://purl.obolibrary.org/obo/CHEBI_23666"},{"id":"A80","pred":"chebi_id","subj":"T80","obj":"http://purl.obolibrary.org/obo/CHEBI_73819"},{"id":"A81","pred":"chebi_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A82","pred":"chebi_id","subj":"T82","obj":"http://purl.obolibrary.org/obo/CHEBI_25902"},{"id":"A83","pred":"chebi_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/CHEBI_37807"},{"id":"A84","pred":"chebi_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/CHEBI_62801"},{"id":"A85","pred":"chebi_id","subj":"T85","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A86","pred":"chebi_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/CHEBI_16236"},{"id":"A87","pred":"chebi_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A88","pred":"chebi_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"}],"text":"N-acetylneuraminic acid (Neu5Ac) was generated with the Hyperchem database. 9-O-acetyl-N-acetylneuraminic acid (9-O-SIA) was retrieved from pdb file 6Q06 [18]. CLQ is N-(7-chloroquinolin-4-yl)-N,N-diéthyl-pentane-1,4-diamine. Its three-dimensioanl structure was retrieved from pdb file # 4V2O [19]. CLQ-OH is (RS)-2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol. CLQ-OH was generated by hydroxylation of CLQ with Hyperchem. Both CLQ and CLQ-OH were energy-minimized and merged with water molecules as described below."}

{"project":"LitCovid-sentences","denotations":[{"id":"T42","span":{"begin":0,"end":75},"obj":"Sentence"},{"id":"T43","span":{"begin":76,"end":159},"obj":"Sentence"},{"id":"T44","span":{"begin":160,"end":225},"obj":"Sentence"},{"id":"T45","span":{"begin":226,"end":298},"obj":"Sentence"},{"id":"T46","span":{"begin":299,"end":378},"obj":"Sentence"},{"id":"T47","span":{"begin":379,"end":439},"obj":"Sentence"},{"id":"T48","span":{"begin":440,"end":533},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"N-acetylneuraminic acid (Neu5Ac) was generated with the Hyperchem database. 9-O-acetyl-N-acetylneuraminic acid (9-O-SIA) was retrieved from pdb file 6Q06 [18]. CLQ is N-(7-chloroquinolin-4-yl)-N,N-diéthyl-pentane-1,4-diamine. Its three-dimensioanl structure was retrieved from pdb file # 4V2O [19]. CLQ-OH is (RS)-2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol. CLQ-OH was generated by hydroxylation of CLQ with Hyperchem. Both CLQ and CLQ-OH were energy-minimized and merged with water molecules as described below."}

{"project":"2_test","denotations":[{"id":"32251731-31792450-48149950","span":{"begin":155,"end":157},"obj":"31792450"},{"id":"32251731-26616259-48149951","span":{"begin":294,"end":296},"obj":"26616259"},{"id":"T55524","span":{"begin":155,"end":157},"obj":"31792450"},{"id":"T86226","span":{"begin":294,"end":296},"obj":"26616259"}],"text":"N-acetylneuraminic acid (Neu5Ac) was generated with the Hyperchem database. 9-O-acetyl-N-acetylneuraminic acid (9-O-SIA) was retrieved from pdb file 6Q06 [18]. CLQ is N-(7-chloroquinolin-4-yl)-N,N-diéthyl-pentane-1,4-diamine. Its three-dimensioanl structure was retrieved from pdb file # 4V2O [19]. CLQ-OH is (RS)-2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol. CLQ-OH was generated by hydroxylation of CLQ with Hyperchem. Both CLQ and CLQ-OH were energy-minimized and merged with water molecules as described below."}