PMC:7128678 / 31807-32488
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 996 | 336-341 | Gene | denotes | ACE-2 | Gene:59272 |
| 997 | 277-278 | Gene | denotes | S | Gene:43740568 |
| 998 | 647-655 | Species | denotes | patients | Tax:9606 |
| 999 | 670-680 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 1000 | 232-242 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 1001 | 346-361 | Chemical | denotes | NTD–ganglioside | |
| 1002 | 616-622 | Chemical | denotes | CLQ-OH | |
| 1003 | 656-664 | Disease | denotes | infected | MESH:D007239 |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T702 | 49-53 | CHEBI:23888;CHEBI:23888 | denotes | drug |
| T703 | 232-242 | SP_7 | denotes | SARS-CoV-2 |
| T704 | 277-286 | PG_1 | denotes | S protein |
| T705 | 296-314 | GO:0033644 | denotes | host cell membrane |
| T706 | 336-341 | G_3;PG_10;PR:000003622 | denotes | ACE-2 |
| T707 | 350-361 | CHEBI:5386;CHEBI:5386 | denotes | ganglioside |
| T708 | 431-436 | CHEBI:23888;CHEBI:23888 | denotes | drugs |
| T709 | 497-502 | NCBITaxon:10239 | denotes | virus |
| T710 | 520-537 | UBERON:0000065 | denotes | respiratory tract |
| T711 | 546-556 | UBERON:0000483 | denotes | epithelium |
| T712 | 670-680 | SP_7 | denotes | SARS-CoV-2 |
| T76020 | 49-53 | CHEBI:23888;CHEBI:23888 | denotes | drug |
| T3558 | 670-680 | SP_7 | denotes | SARS-CoV-2 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T227 | 279-286 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T228 | 301-314 | Body_part | denotes | cell membrane | http://purl.org/sig/ont/fma/fma63841 |
| T229 | 301-305 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T230 | 350-361 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
| T231 | 520-537 | Body_part | denotes | respiratory tract | http://purl.org/sig/ont/fma/fma265130 |
| T232 | 538-556 | Body_part | denotes | surface epithelium | http://purl.org/sig/ont/fma/fma70997 |
| T233 | 546-556 | Body_part | denotes | epithelium | http://purl.org/sig/ont/fma/fma9639 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T23 | 520-537 | Body_part | denotes | respiratory tract | http://purl.obolibrary.org/obo/UBERON_0000065 |
| T24 | 538-556 | Body_part | denotes | surface epithelium | http://purl.obolibrary.org/obo/UBERON_0006677 |
| T25 | 546-556 | Body_part | denotes | epithelium | http://purl.obolibrary.org/obo/UBERON_0000483 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T151 | 232-240 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T152 | 346-349 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
| T154 | 670-678 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T266 | 116-117 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T267 | 174-181 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | testing |
| T268 | 301-305 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T269 | 306-314 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T270 | 497-502 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T271 | 546-556 | http://purl.obolibrary.org/obo/UBERON_0000483 | denotes | epithelium |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T736 | 49-53 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T737 | 279-286 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T738 | 350-361 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T739 | 431-436 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T246 | 0-13 | Sentence | denotes | 5 Conclusion |
| T247 | 14-106 | Sentence | denotes | Given the global health emergency, drug repurposing is obviously the option of choice [2,3]. |
| T248 | 107-315 | Sentence | denotes | However, a considerable amount of time could be saved by in-silico testing to determine the capability of any potential anti-SARS-CoV-2 to disrupt the interaction of the S protein with the host cell membrane. |
| T249 | 316-557 | Sentence | denotes | Applied to both RBD–ACE-2 and NTD–ganglioside interactions, this molecular modelling method will help select those drugs that are likely to interfere with the initial attachment of virus particles to the respiratory tract surface epithelium. |
| T250 | 558-681 | Sentence | denotes | The study data support the use of CLQ, and preferentially CLQ-OH, as initial therapy for patients infected with SARS-CoV-2. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32251731-22743966-48149964 | 101-102 | 22743966 | denotes | 2 |
| T86521 | 101-102 | 22743966 | denotes | 2 |