PMC:7128678 / 14546-15650
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 459 | 789-790 | Gene | denotes | S | Gene:43740568 |
| 460 | 718-719 | Gene | denotes | S | Gene:43740568 |
| 461 | 614-615 | Gene | denotes | S | Gene:43740568 |
| 462 | 505-506 | Gene | denotes | S | Gene:43740568 |
| 463 | 446-456 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 464 | 457-462 | Gene | denotes | spike | Gene:43740568 |
| 465 | 1077-1088 | Chemical | denotes | ganglioside | MESH:D005732 |
| 472 | 283-284 | Gene | denotes | S | Gene:43740568 |
| 473 | 215-216 | Gene | denotes | S | Gene:43740568 |
| 474 | 49-59 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 475 | 204-214 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 476 | 96-108 | Chemical | denotes | gangliosides | MESH:D005732 |
| 477 | 168-174 | Chemical | denotes | CLQ-OH |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T322 | 49-59 | SP_7 | denotes | SARS-CoV-2 |
| T323 | 80-95 | GO:0005886 | denotes | plasma membrane |
| T324 | 96-108 | CHEBI:5386;CHEBI:5386 | denotes | gangliosides |
| T325 | 204-214 | SP_7 | denotes | SARS-CoV-2 |
| T326 | 215-224 | PG_1 | denotes | S protein |
| T327 | 324-331 | SO:0000417 | denotes | domains |
| T328 | 349-354 | NCBITaxon:10239;GO:0019031 | denotes | viral |
| T329 | 355-363 | GO:0019031 | denotes | envelope |
| T330 | 378-392 | SO:0000409 | denotes | binding region |
| T331 | 446-456 | SP_7 | denotes | SARS-CoV-2 |
| T332 | 505-514 | PG_1 | denotes | S protein |
| T333 | 614-623 | PG_1 | denotes | S protein |
| T334 | 639-646 | SO:0001117 | denotes | α-helix |
| T335 | 718-727 | PG_1 | denotes | S protein |
| T336 | 789-798 | PG_1 | denotes | S protein |
| T337 | 827-833 | SO:0000417 | denotes | domain |
| T338 | 854-863 | PG_1 | denotes | S protein |
| T339 | 1077-1088 | CHEBI:28892;CHEBI:28892 | denotes | ganglioside |
| T340 | 1097-1103 | SO:0000417 | denotes | domain |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T66 | 80-95 | Body_part | denotes | plasma membrane | http://purl.org/sig/ont/fma/fma63841 |
| T67 | 96-108 | Body_part | denotes | gangliosides | http://purl.org/sig/ont/fma/fma82816 |
| T68 | 217-224 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T69 | 285-293 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T70 | 467-474 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T71 | 507-514 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T72 | 616-623 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T73 | 641-646 | Body_part | denotes | helix | http://purl.org/sig/ont/fma/fma60992 |
| T74 | 720-727 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T75 | 791-798 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T76 | 856-863 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T77 | 1013-1023 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
| T78 | 1077-1088 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T7 | 641-646 | Body_part | denotes | helix | http://purl.obolibrary.org/obo/UBERON_0002488 |
| T8 | 686-703 | Body_part | denotes | Surface structure | http://purl.obolibrary.org/obo/UBERON_0003102 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T30 | 49-57 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T31 | 204-212 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T32 | 407-410 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
| T34 | 446-454 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T35 | 835-838 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
| T37 | 900-903 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
| T39 | 1040-1043 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T95 | 80-86 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T96 | 87-95 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T97 | 250-251 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T98 | 271-272 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T99 | 477-478 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T100 | 515-518 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T101 | 519-520 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T102 | 579-580 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
| T103 | 890-891 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T104 | 1013-1032 | http://purl.obolibrary.org/obo/CHEBI_33708 | denotes | amino acid residues |
| T105 | 1013-1032 | http://purl.obolibrary.org/obo/PR_000036907 | denotes | amino acid residues |
| T106 | 1065-1066 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T278 | 96-108 | Chemical | denotes | gangliosides | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T279 | 217-224 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T280 | 285-293 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T281 | 467-474 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T282 | 507-514 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T283 | 616-623 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T284 | 720-727 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T285 | 791-798 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T286 | 856-863 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T287 | 1013-1023 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T288 | 1013-1018 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T289 | 1019-1023 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T290 | 1077-1088 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T106 | 0-175 | Sentence | denotes | The next step of this study was to determine how SARS-CoV-2 could interact with plasma membrane gangliosides, and whether such interaction could be affected by CLQ and CLQ-OH. |
| T107 | 176-255 | Sentence | denotes | The global structure of the SARS-CoV-2 S protein [16] is shown in Fig. 5 (a–d). |
| T108 | 256-411 | Sentence | denotes | It consists of a trimer of S proteins, each harbouring two distinct domains distant from the viral envelope: the receptor-binding region (RBD) and the NTD. |
| T109 | 412-1104 | Sentence | denotes | Fig. 5 Structural features of the SARS-CoV-2 spike (S) protein. (a) Trimeric structure (each S protein has a distinct surface colour, ‘blue’, ‘yellow’ and ‘purple’). (b) Ribbon representation of ‘blue’ S protein in the trimer (α-helix, red; β-strand, blue; coil, grey). (c) Surface structure of the ‘blue’ S protein isolated from the trimer. (d) Ribbon structure of the ‘blue’ S protein. (e) Zoom on the N-terminal domain (NTD) of the ‘blue’ S protein. (f,g) Molecular model of a minimal NTD obtained with Hyperchem [ribbon in representation in (f), surface rendering in (g)]. (h) Highlighting of the amino acid residues of the NTD that could belong to a potential ganglioside-binding domain. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32251731-32075877-48149953 | 226-228 | 32075877 | denotes | 16 |
| T65765 | 226-228 | 32075877 | denotes | 16 |