PMC:7128678 / 11227-11677 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"410","span":{"begin":247,"end":252},"obj":"Species"},{"id":"412","span":{"begin":7,"end":19},"obj":"Chemical"},{"id":"413","span":{"begin":88,"end":94},"obj":"Chemical"},{"id":"414","span":{"begin":109,"end":120},"obj":"Chemical"},{"id":"415","span":{"begin":189,"end":204},"obj":"Chemical"},{"id":"416","span":{"begin":269,"end":281},"obj":"Chemical"},{"id":"417","span":{"begin":358,"end":369},"obj":"Chemical"},{"id":"418","span":{"begin":433,"end":443},"obj":"Chemical"}],"attributes":[{"id":"A410","pred":"tao:has_database_id","subj":"410","obj":"Tax:9606"},{"id":"A412","pred":"tao:has_database_id","subj":"412","obj":"MESH:D005732"},{"id":"A414","pred":"tao:has_database_id","subj":"414","obj":"MESH:D019158"},{"id":"A415","pred":"tao:has_database_id","subj":"415","obj":"MESH:D005677"},{"id":"A416","pred":"tao:has_database_id","subj":"416","obj":"MESH:D005732"},{"id":"A417","pred":"tao:has_database_id","subj":"417","obj":"MESH:D005732"},{"id":"A418","pred":"tao:has_database_id","subj":"418","obj":"MESH:D002241"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"ns and gangliosides. Molecular modelling approaches were used to assess whether CLQ and CLQ-OH can recognize sialic acid units in their natural molecular environment. In these simulations, ganglioside GM1 was chosen as a representative example of human plasma membrane gangliosides. A first series of simulations was performed with CLQ. When merged with the ganglioside, CLQ had two distinct binding sites, both located in the polar saccharide part o"}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T248","span":{"begin":7,"end":19},"obj":"CHEBI:28892;CHEBI:28892"},{"id":"T249","span":{"begin":109,"end":120},"obj":"CHEBI:26667;CHEBI:26667"},{"id":"T250","span":{"begin":189,"end":200},"obj":"CHEBI:5386;CHEBI:5386"},{"id":"T251","span":{"begin":247,"end":252},"obj":"SP_6;NCBITaxon:9606"},{"id":"T252","span":{"begin":253,"end":268},"obj":"GO:0005886"},{"id":"T253","span":{"begin":269,"end":281},"obj":"CHEBI:28892;CHEBI:28892"},{"id":"T254","span":{"begin":358,"end":369},"obj":"CHEBI:28892;CHEBI:28892"},{"id":"T255","span":{"begin":392,"end":405},"obj":"SO:0000409"},{"id":"T256","span":{"begin":433,"end":443},"obj":"CHEBI:32111;CHEBI:32111"}],"text":"ns and gangliosides. Molecular modelling approaches were used to assess whether CLQ and CLQ-OH can recognize sialic acid units in their natural molecular environment. In these simulations, ganglioside GM1 was chosen as a representative example of human plasma membrane gangliosides. A first series of simulations was performed with CLQ. When merged with the ganglioside, CLQ had two distinct binding sites, both located in the polar saccharide part o"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T45","span":{"begin":7,"end":19},"obj":"Body_part"},{"id":"T46","span":{"begin":189,"end":200},"obj":"Body_part"},{"id":"T47","span":{"begin":253,"end":268},"obj":"Body_part"},{"id":"T48","span":{"begin":269,"end":281},"obj":"Body_part"},{"id":"T49","span":{"begin":358,"end":369},"obj":"Body_part"}],"attributes":[{"id":"A45","pred":"fma_id","subj":"T45","obj":"http://purl.org/sig/ont/fma/fma82816"},{"id":"A46","pred":"fma_id","subj":"T46","obj":"http://purl.org/sig/ont/fma/fma82816"},{"id":"A47","pred":"fma_id","subj":"T47","obj":"http://purl.org/sig/ont/fma/fma63841"},{"id":"A48","pred":"fma_id","subj":"T48","obj":"http://purl.org/sig/ont/fma/fma82816"},{"id":"A49","pred":"fma_id","subj":"T49","obj":"http://purl.org/sig/ont/fma/fma82816"}],"text":"ns and gangliosides. Molecular modelling approaches were used to assess whether CLQ and CLQ-OH can recognize sialic acid units in their natural molecular environment. In these simulations, ganglioside GM1 was chosen as a representative example of human plasma membrane gangliosides. A first series of simulations was performed with CLQ. When merged with the ganglioside, CLQ had two distinct binding sites, both located in the polar saccharide part o"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T71","span":{"begin":219,"end":220},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T72","span":{"begin":247,"end":252},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T73","span":{"begin":253,"end":259},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T74","span":{"begin":260,"end":268},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T75","span":{"begin":283,"end":284},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"ns and gangliosides. Molecular modelling approaches were used to assess whether CLQ and CLQ-OH can recognize sialic acid units in their natural molecular environment. In these simulations, ganglioside GM1 was chosen as a representative example of human plasma membrane gangliosides. A first series of simulations was performed with CLQ. When merged with the ganglioside, CLQ had two distinct binding sites, both located in the polar saccharide part o"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T184","span":{"begin":7,"end":19},"obj":"Chemical"},{"id":"T185","span":{"begin":109,"end":120},"obj":"Chemical"},{"id":"T186","span":{"begin":116,"end":120},"obj":"Chemical"},{"id":"T187","span":{"begin":189,"end":204},"obj":"Chemical"},{"id":"T189","span":{"begin":189,"end":200},"obj":"Chemical"},{"id":"T190","span":{"begin":201,"end":204},"obj":"Chemical"},{"id":"T191","span":{"begin":269,"end":281},"obj":"Chemical"},{"id":"T192","span":{"begin":358,"end":369},"obj":"Chemical"},{"id":"T193","span":{"begin":433,"end":443},"obj":"Chemical"}],"attributes":[{"id":"A184","pred":"chebi_id","subj":"T184","obj":"http://purl.obolibrary.org/obo/CHEBI_28892"},{"id":"A185","pred":"chebi_id","subj":"T185","obj":"http://purl.obolibrary.org/obo/CHEBI_26667"},{"id":"A186","pred":"chebi_id","subj":"T186","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A187","pred":"chebi_id","subj":"T187","obj":"http://purl.obolibrary.org/obo/CHEBI_18216"},{"id":"A188","pred":"chebi_id","subj":"T187","obj":"http://purl.obolibrary.org/obo/CHEBI_61048"},{"id":"A189","pred":"chebi_id","subj":"T189","obj":"http://purl.obolibrary.org/obo/CHEBI_28892"},{"id":"A190","pred":"chebi_id","subj":"T190","obj":"http://purl.obolibrary.org/obo/CHEBI_73110"},{"id":"A191","pred":"chebi_id","subj":"T191","obj":"http://purl.obolibrary.org/obo/CHEBI_28892"},{"id":"A192","pred":"chebi_id","subj":"T192","obj":"http://purl.obolibrary.org/obo/CHEBI_28892"},{"id":"A193","pred":"chebi_id","subj":"T193","obj":"http://purl.obolibrary.org/obo/CHEBI_16646"}],"text":"ns and gangliosides. Molecular modelling approaches were used to assess whether CLQ and CLQ-OH can recognize sialic acid units in their natural molecular environment. In these simulations, ganglioside GM1 was chosen as a representative example of human plasma membrane gangliosides. A first series of simulations was performed with CLQ. When merged with the ganglioside, CLQ had two distinct binding sites, both located in the polar saccharide part o"}

{"project":"LitCovid-PD-GlycoEpitope","denotations":[{"id":"T3","span":{"begin":201,"end":204},"obj":"GlycoEpitope"}],"attributes":[{"id":"A3","pred":"glyco_epitope_db_id","subj":"T3","obj":"http://www.glycoepitope.jp/epitopes/EP0050"}],"text":"ns and gangliosides. Molecular modelling approaches were used to assess whether CLQ and CLQ-OH can recognize sialic acid units in their natural molecular environment. In these simulations, ganglioside GM1 was chosen as a representative example of human plasma membrane gangliosides. A first series of simulations was performed with CLQ. When merged with the ganglioside, CLQ had two distinct binding sites, both located in the polar saccharide part o"}

{"project":"LitCovid-sentences","denotations":[{"id":"T85","span":{"begin":21,"end":166},"obj":"Sentence"},{"id":"T86","span":{"begin":167,"end":282},"obj":"Sentence"},{"id":"T87","span":{"begin":283,"end":336},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"ns and gangliosides. Molecular modelling approaches were used to assess whether CLQ and CLQ-OH can recognize sialic acid units in their natural molecular environment. In these simulations, ganglioside GM1 was chosen as a representative example of human plasma membrane gangliosides. A first series of simulations was performed with CLQ. When merged with the ganglioside, CLQ had two distinct binding sites, both located in the polar saccharide part o"}