PMC:7127386 / 8389-10625
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 220 | 1866-1879 | Gene | denotes | neuraminidase | Gene:4758 |
| 221 | 24-34 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 222 | 256-261 | Species | denotes | Ebola | Tax:1570291 |
| 223 | 265-275 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 224 | 831-836 | Species | denotes | HIV-1 | Tax:11676 |
| 225 | 194-204 | Chemical | denotes | Remdesivir | MESH:C000606551 |
| 226 | 205-214 | Chemical | denotes | adenosine | MESH:D000241 |
| 227 | 565-574 | Chemical | denotes | adenosine | MESH:D000241 |
| 228 | 782-791 | Chemical | denotes | adenosine | MESH:D000241 |
| 229 | 899-908 | Chemical | denotes | adenosine | MESH:D000241 |
| 230 | 1015-1024 | Chemical | denotes | Lopinavir | MESH:D061466 |
| 231 | 392-401 | Disease | denotes | infection | MESH:D007239 |
| 232 | 493-522 | Disease | denotes | chronic hepatitis C infection | MESH:D019698 |
| 233 | 609-630 | Disease | denotes | fever virus infection | MESH:D005334 |
| 234 | 724-739 | Disease | denotes | virus infection | MESH:D001102 |
| 235 | 963-983 | Disease | denotes | lymphocytic leukemia | MESH:D007945 |
| 236 | 1074-1089 | Disease | denotes | HIV-1 infection | MESH:D015658 |
| 237 | 1212-1227 | Disease | denotes | HIV-1 infection | MESH:D015658 |
| 238 | 1375-1394 | Disease | denotes | invasive amoebiasis | MESH:D000562 |
| 239 | 1490-1504 | Disease | denotes | skin infection | MESH:D007239 |
| 240 | 1635-1649 | Disease | denotes | skin infection | MESH:D007239 |
| 241 | 1739-1745 | Disease | denotes | cancer | MESH:D009369 |
| 242 | 1773-1797 | Disease | denotes | chronic myeloid leukemia | MESH:D015464 |
| 243 | 1927-1936 | Disease | denotes | infection | MESH:D007239 |
| 244 | 2055-2064 | Disease | denotes | infection | MESH:D007239 |
| 245 | 2194-2207 | Disease | denotes | schizophrenia | MESH:D012559 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T23 | 177-180 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T24 | 831-834 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T25 | 950-954 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T26 | 963-974 | Body_part | denotes | lymphocytic | http://purl.org/sig/ont/fma/fma62863 |
| T27 | 1074-1077 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T28 | 1212-1215 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T29 | 1490-1494 | Body_part | denotes | skin | http://purl.org/sig/ont/fma/fma7163 |
| T30 | 1635-1639 | Body_part | denotes | skin | http://purl.org/sig/ont/fma/fma7163 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T5 | 1490-1494 | Body_part | denotes | skin | http://purl.obolibrary.org/obo/UBERON_0000014 |
| T6 | 1635-1639 | Body_part | denotes | skin | http://purl.obolibrary.org/obo/UBERON_0000014 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T39 | 24-32 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T40 | 133-143 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T41 | 256-261 | Disease | denotes | Ebola | http://purl.obolibrary.org/obo/MONDO_0005737 |
| T42 | 265-273 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T43 | 382-401 | Disease | denotes | influenza infection | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T44 | 392-401 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T45 | 493-512 | Disease | denotes | chronic hepatitis C | http://purl.obolibrary.org/obo/MONDO_0005231|http://purl.obolibrary.org/obo/MONDO_0005354 |
| T47 | 493-510 | Disease | denotes | chronic hepatitis | http://purl.obolibrary.org/obo/MONDO_0002251 |
| T48 | 513-522 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T49 | 602-614 | Disease | denotes | yellow fever | http://purl.obolibrary.org/obo/MONDO_0020502 |
| T50 | 615-630 | Disease | denotes | virus infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T51 | 621-630 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T52 | 717-739 | Disease | denotes | dengue virus infection | http://purl.obolibrary.org/obo/MONDO_0005502 |
| T53 | 724-739 | Disease | denotes | virus infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T54 | 730-739 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T55 | 948-983 | Disease | denotes | B-cell chronic lymphocytic leukemia | http://purl.obolibrary.org/obo/MONDO_0004948 |
| T56 | 963-983 | Disease | denotes | lymphocytic leukemia | http://purl.obolibrary.org/obo/MONDO_0005402 |
| T57 | 975-983 | Disease | denotes | leukemia | http://purl.obolibrary.org/obo/MONDO_0005059 |
| T58 | 1080-1089 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T59 | 1218-1227 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T60 | 1384-1394 | Disease | denotes | amoebiasis | http://purl.obolibrary.org/obo/MONDO_0005644 |
| T61 | 1490-1504 | Disease | denotes | skin infection | http://purl.obolibrary.org/obo/MONDO_0021201 |
| T62 | 1495-1504 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T63 | 1635-1649 | Disease | denotes | skin infection | http://purl.obolibrary.org/obo/MONDO_0021201 |
| T64 | 1640-1649 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T65 | 1739-1745 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T66 | 1773-1797 | Disease | denotes | chronic myeloid leukemia | http://purl.obolibrary.org/obo/MONDO_0011996 |
| T67 | 1781-1797 | Disease | denotes | myeloid leukemia | http://purl.obolibrary.org/obo/MONDO_0004643 |
| T68 | 1789-1797 | Disease | denotes | leukemia | http://purl.obolibrary.org/obo/MONDO_0005059 |
| T69 | 1917-1936 | Disease | denotes | influenza infection | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T70 | 1927-1936 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T71 | 2045-2064 | Disease | denotes | influenza infection | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T72 | 2055-2064 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T73 | 2194-2207 | Disease | denotes | schizophrenia | http://purl.obolibrary.org/obo/MONDO_0005090 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T53 | 615-620 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T54 | 724-729 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T55 | 948-954 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B-cell |
| T56 | 1490-1494 | http://purl.obolibrary.org/obo/UBERON_0000014 | denotes | skin |
| T57 | 1490-1494 | http://purl.obolibrary.org/obo/UBERON_0001003 | denotes | skin |
| T58 | 1490-1494 | http://purl.obolibrary.org/obo/UBERON_0002097 | denotes | skin |
| T59 | 1490-1494 | http://purl.obolibrary.org/obo/UBERON_0002199 | denotes | skin |
| T60 | 1490-1494 | http://www.ebi.ac.uk/efo/EFO_0000962 | denotes | skin |
| T61 | 1529-1537 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
| T62 | 1635-1639 | http://purl.obolibrary.org/obo/UBERON_0000014 | denotes | skin |
| T63 | 1635-1639 | http://purl.obolibrary.org/obo/UBERON_0001003 | denotes | skin |
| T64 | 1635-1639 | http://purl.obolibrary.org/obo/UBERON_0002097 | denotes | skin |
| T65 | 1635-1639 | http://purl.obolibrary.org/obo/UBERON_0002199 | denotes | skin |
| T66 | 1635-1639 | http://www.ebi.ac.uk/efo/EFO_0000962 | denotes | skin |
| T67 | 1674-1682 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
| T68 | 1944-1946 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 45 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T127 | 74-85 | Chemical | denotes | application | http://purl.obolibrary.org/obo/CHEBI_33232 |
| T128 | 205-214 | Chemical | denotes | adenosine | http://purl.obolibrary.org/obo/CHEBI_16335 |
| T129 | 444-453 | Chemical | denotes | guanosine | http://purl.obolibrary.org/obo/CHEBI_16750 |
| T130 | 565-574 | Chemical | denotes | adenosine | http://purl.obolibrary.org/obo/CHEBI_16335 |
| T131 | 782-791 | Chemical | denotes | adenosine | http://purl.obolibrary.org/obo/CHEBI_16335 |
| T132 | 889-898 | Chemical | denotes | phosphate | http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474 |
| T136 | 899-908 | Chemical | denotes | adenosine | http://purl.obolibrary.org/obo/CHEBI_16335 |
| T137 | 1015-1024 | Chemical | denotes | Lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
| T138 | 1025-1043 | Chemical | denotes | protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258 |
| T140 | 1034-1043 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T141 | 1110-1119 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
| T142 | 1163-1181 | Chemical | denotes | protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258 |
| T144 | 1172-1181 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T145 | 1309-1316 | Chemical | denotes | Emetine | http://purl.obolibrary.org/obo/CHEBI_4781 |
| T146 | 1317-1330 | Chemical | denotes | hydrochloride | http://purl.obolibrary.org/obo/CHEBI_36807 |
| T147 | 1427-1450 | Chemical | denotes | Oritavancin diphosphate | http://purl.obolibrary.org/obo/CHEBI_83305 |
| T148 | 1439-1450 | Chemical | denotes | diphosphate | http://purl.obolibrary.org/obo/CHEBI_18361|http://purl.obolibrary.org/obo/CHEBI_33019 |
| T150 | 1451-1462 | Chemical | denotes | antibiotics | http://purl.obolibrary.org/obo/CHEBI_33281 |
| T151 | 1582-1595 | Chemical | denotes | hydrochloride | http://purl.obolibrary.org/obo/CHEBI_36807 |
| T152 | 1596-1607 | Chemical | denotes | antibiotics | http://purl.obolibrary.org/obo/CHEBI_33281 |
| T153 | 1716-1733 | Chemical | denotes | Homoharringtonine | http://purl.obolibrary.org/obo/CHEBI_71019 |
| T154 | 1831-1854 | Chemical | denotes | Oseltamivir carboxylate | http://purl.obolibrary.org/obo/CHEBI_73139 |
| T155 | 1831-1842 | Chemical | denotes | Oseltamivir | http://purl.obolibrary.org/obo/CHEBI_7798 |
| T156 | 1855-1864 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T157 | 1866-1889 | Chemical | denotes | neuraminidase inhibitor | http://purl.obolibrary.org/obo/CHEBI_52425 |
| T158 | 1880-1889 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T159 | 1979-1983 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T160 | 1984-1993 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T161 | 2008-2017 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T162 | 2099-2127 | Chemical | denotes | Chlorpromazine hydrochloride | http://purl.obolibrary.org/obo/CHEBI_3649 |
| T163 | 2099-2113 | Chemical | denotes | Chlorpromazine | http://purl.obolibrary.org/obo/CHEBI_3647 |
| T164 | 2114-2127 | Chemical | denotes | hydrochloride | http://purl.obolibrary.org/obo/CHEBI_36807 |
| T165 | 2128-2138 | Chemical | denotes | antagonist | http://purl.obolibrary.org/obo/CHEBI_48706 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T47 | 0-47 | Sentence | denotes | Compounds Inhibition of SARS-CoV-2 in vitro, μM |
| T48 | 48-93 | Sentence | denotes | Name Bioactivity Clinical application CAS No. |
| T49 | 94-193 | Sentence | denotes | CC50, μMa CPE inhibitionb Reduction in infectious virusc (EC50) Reduction in viral RNA copyd (EC50) |
| T50 | 194-308 | Sentence | denotes | Remdesivir adenosine analogue Phase 4 trials for treatment of Ebola or SARS-CoV-2 1809249-37-3 >100 25 23.15 26.90 |
| T51 | 309-433 | Sentence | denotes | Favipiravir guanineanalogue Approved in Japan and China for treatment of influenza infection 259793-96-9 >100 >100 >100 >100 |
| T52 | 434-552 | Sentence | denotes | Ribavirin guanosine analogue FDA approved for treatment of chronic hepatitis C infection 36791-04-5 >100 500 >500 >500 |
| T53 | 553-661 | Sentence | denotes | Galidesivir adenosine analogue Phase 2 trial for yellow fever virus infection 222631-44-9 >100 100 >100 >100 |
| T54 | 662-766 | Sentence | denotes | R-1479 cytidineanalogue Phase 2 trial for treatment of dengue virus infection 478182-28-4 >100 >100 N.D. |
| T55 | 767-771 | Sentence | denotes | N.D. |
| T56 | 772-871 | Sentence | denotes | Tenofovor adenosine analogue FDA approved for treatment of HIV-1 and HBV 147127-20-6 >100 >100 N.D. |
| T57 | 872-876 | Sentence | denotes | N.D. |
| T58 | 877-1009 | Sentence | denotes | Fludarabine phosphate adenosine analogue FDA approved for treatment of B-cell chronic lymphocytic leukemia 75607-67-9 >100 >100 N.D. |
| T59 | 1010-1014 | Sentence | denotes | N.D. |
| T60 | 1015-1152 | Sentence | denotes | Lopinavir protease inhibitor FDA approved for treatment of HIV-1 infection in combination with ritonavir 192725-17-0 49.75 25 26.63 26.10 |
| T61 | 1153-1308 | Sentence | denotes | Ritonavir protease inhibitor FDA approved for treatment of HIV-1 infection in combination with other antiretroviral agents 155213-67-5 48.91 >100 >100 >100 |
| T62 | 1309-1426 | Sentence | denotes | Emetine hydrochloride anti-protozoal Approved in China for severe invasive amoebiasis 316-42-7 56.46 1.5625 0.46 0.50 |
| T63 | 1427-1564 | Sentence | denotes | Oritavancin diphosphate antibiotics FDA approved treatment for skin infection caused by Gram positive bacteria 192564-14-0 N.D. >100 N.D. |
| T64 | 1565-1569 | Sentence | denotes | N.D. |
| T65 | 1570-1710 | Sentence | denotes | Dalbavancin hydrochloride antibiotics FDA approved treatment for skin infection caused by Gram positive bacteria 2227366-51-8 N.D. >100 N.D. |
| T66 | 1711-1715 | Sentence | denotes | N.D. |
| T67 | 1716-1830 | Sentence | denotes | Homoharringtonine anti-cancer FDA approved treatment for chronic myeloid leukemia 26833-87-4 59.75 3.125 2.55 2.14 |
| T68 | 1831-1968 | Sentence | denotes | Oseltamivir carboxylate antiviral, neuraminidase inhibitor FDA approved treatment for influenza infection 187227-45-8 >100 >100 >100 >100 |
| T69 | 1969-2098 | Sentence | denotes | Baloxivir acid antiviral, endonuclease inhibitor FDA approved treatment for influenza infection 1985605-59-1 85.90 >100 >100 >100 |
| T70 | 2099-2231 | Sentence | denotes | Chlorpromazine hydrochloride antagonist for post-synaptic receptors FDA approved treatment for schizophrenia 69-09-0 21.29 >100 N.D. |
| T71 | 2232-2236 | Sentence | denotes | N.D. |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T2 | 493-510 | Phenotype | denotes | chronic hepatitis | http://purl.obolibrary.org/obo/HP_0200123 |
| T3 | 609-614 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T4 | 955-983 | Phenotype | denotes | chronic lymphocytic leukemia | http://purl.obolibrary.org/obo/HP_0005550 |
| T5 | 1490-1504 | Phenotype | denotes | skin infection | http://purl.obolibrary.org/obo/HP_0100658 |
| T6 | 1635-1649 | Phenotype | denotes | skin infection | http://purl.obolibrary.org/obo/HP_0100658 |
| T7 | 1739-1745 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
| T8 | 1773-1797 | Phenotype | denotes | chronic myeloid leukemia | http://purl.obolibrary.org/obo/HP_0005506 |
| T9 | 2194-2207 | Phenotype | denotes | schizophrenia | http://purl.obolibrary.org/obo/HP_0100753 |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T237 | 108-131 | CHEBI:17883;CHEBI:17883 | denotes | inhibitionb Reduction i |
| T238 | 136-149 | GO:0098794 | denotes | ectious virus |
| T239 | 284-293 | CHEBI:36357;CHEBI:36357 | denotes | 37-3 >100 |
| T240 | 297-301 | CL_6 | denotes | 23.1 |
| T241 | 468-477 | CHEBI:28201;CHEBI:28201;DG_29 | denotes | pproved f |
| T242 | 535-545 | SP_7 | denotes | 100 500 >5 |
| T243 | 546-551 | NCBITaxon:10239 | denotes | 0 >50 |
| T244 | 555-559 | NCBITaxon:10633;CL_6 | denotes | lide |
| T245 | 607-616 | CHEBI:36357;CHEBI:36357 | denotes | w fever v |
| T246 | 687-695 | CHEBI:36357;CHEBI:36357 | denotes | hase 2 t |
| T247 | 822-827 | NCBITaxon:10239 | denotes | tment |
| T248 | 917-922 | NCBITaxon:10239 | denotes | FDA |
| T249 | 1034-1044 | DG_28 | denotes | inhibitor |
| T250 | 1050-1058 | DG_23;CHEBI:31781;CHEBI:31781 | denotes | proved f |
| T251 | 1088-1095 | CHEBI:4781;CHEBI:4781 | denotes | n in co |
| T252 | 1096-1111 | CHEBI:50488;CHEBI:50488 | denotes | bination with r |
| T253 | 1124-1134 | SP_7 | denotes | 25-17-0 49 |
| T254 | 1135-1140 | NCBITaxon:10239 | denotes | 75 25 |
| T255 | 1162-1167 | NCBITaxon:10239 | denotes | prot |
| T256 | 1252-1256 | CL_6 | denotes | r an |
| T257 | 1347-1356 | CHEBI:36357;CHEBI:36357 | denotes | pproved i |
| T71435 | 1409-1418 | CHEBI:36357;CHEBI:36357 | denotes | 1.5625 0 |
| T63695 | 1427-1437 | SP_7 | denotes | Oritavanci |
| T53400 | 1441-1445 | CL_6 | denotes | phos |
| T59680 | 1521-1530 | CHEBI:36357;CHEBI:36357 | denotes | ositive b |
| T44493 | 1534-1538 | CL_6 | denotes | ria |
| T11771 | 1704-1713 | CHEBI:63580;DG_29;CHEBI:63580 | denotes | 0 N.D. N. |
| T48987 | 1771-1781 | SP_7 | denotes | r chronic |
| T34879 | 1782-1787 | NCBITaxon:10239 | denotes | yeloi |
| T1975 | 1791-1795 | NCBITaxon:10633;CL_6 | denotes | ukem |
| T59560 | 1843-1852 | CHEBI:36357;CHEBI:36357 | denotes | carboxyla |
| T1290 | 1923-1931 | CHEBI:36357;CHEBI:36357 | denotes | nza infe |
| T5891 | 2062-2067 | NCBITaxon:10239 | denotes | on 19 |
| T75776 | 2159-2164 | NCBITaxon:10239 | denotes | cepto |