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PMC:7127067 / 15458-17789 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T47 359-362 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T48 1704-1707 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T131 37-45 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T132 46-55 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T133 206-214 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T134 215-224 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T135 404-419 Disease denotes virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T136 410-419 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T137 908-927 Disease denotes 2019-nCoV infection http://purl.obolibrary.org/obo/MONDO_0100096
T138 918-927 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T139 1083-1091 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T140 1092-1101 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T141 1312-1321 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T142 1322-1338 Disease denotes virus infections http://purl.obolibrary.org/obo/MONDO_0005108
T143 1420-1428 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T144 1429-1438 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T145 1615-1623 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T146 1624-1633 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T147 1843-1851 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T148 1852-1862 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T149 1926-1934 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T150 2152-2160 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T151 2161-2170 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T129 112-113 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T130 250-256 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T131 404-409 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T132 626-627 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T133 982-987 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T134 1002-1003 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T135 1103-1105 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T136 1131-1132 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T137 1245-1248 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T138 1322-1327 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T139 1689-1696 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T140 1976-1982 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T141 2043-2049 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T142 2118-2119 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T143 2129-2136 http://purl.obolibrary.org/obo/NCBITaxon_9443 denotes primate
T144 2226-2233 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T145 2281-2282 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T146 2307-2312 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T15 171-186 Chemical denotes antiviral drugs http://purl.obolibrary.org/obo/CHEBI_36044
T16 171-180 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T17 181-186 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T18 308-323 Chemical denotes antiviral drugs http://purl.obolibrary.org/obo/CHEBI_36044
T19 308-317 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T20 318-323 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T21 329-339 Chemical denotes Nucleoside http://purl.obolibrary.org/obo/CHEBI_33838
T22 359-382 Chemical denotes HIV-protease inhibitors http://purl.obolibrary.org/obo/CHEBI_35660
T23 363-382 Chemical denotes protease inhibitors http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T25 372-382 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T26 439-448 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T27 570-585 Chemical denotes antiviral drugs http://purl.obolibrary.org/obo/CHEBI_36044
T28 570-579 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T29 580-585 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T30 661-672 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T31 681-690 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T32 699-708 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T33 754-765 Chemical denotes ganciclovir http://purl.obolibrary.org/obo/CHEBI_465284
T34 832-841 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T35 842-852 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T36 857-868 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T37 944-953 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T38 1377-1381 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T39 1564-1574 Chemical denotes antivirals http://purl.obolibrary.org/obo/CHEBI_22587
T40 1588-1592 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T41 1642-1651 Chemical denotes Lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T42 1663-1687 Chemical denotes Neuraminidase inhibitors http://purl.obolibrary.org/obo/CHEBI_52425
T43 1677-1687 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T44 1689-1696 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T45 1718-1728 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T46 1824-1829 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T11 1704-1717 http://purl.obolibrary.org/obo/GO_0032774 denotes RNA synthesis
T12 1708-1717 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T13 2307-2330 http://purl.obolibrary.org/obo/GO_0019048 denotes virus-host interactions

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T110 0-136 Sentence denotes The person-to-person transmission of COVID-19 infection led to the isolation of patients that were administered a variety of treatments.
T111 137-257 Sentence denotes At present, there are no specific antiviral drugs or vaccine against COVID-19 infection for potential therapy of humans.
T112 258-471 Sentence denotes The only option available is using broad-spectrum antiviral drugs like Nucleoside analogues and also HIV-protease inhibitors that could attenuate virus infection until the specific antiviral becomes available [7].
T113 472-586 Sentence denotes The treatment that have so far been attempted showed that 75 patients were administrated existing antiviral drugs.
T114 587-785 Sentence denotes The course of treatment included twice a day oral administration of 75 mg oseltamivir, 500 mg lopinavir, 500 mg ritonavir and the intravenous administration of 0·25 g ganciclovir for 3–14 days [26].
T115 786-937 Sentence denotes Another report showed that the broad-spectrum antiviral remdesivir and chloroquine are highly effective in the control of 2019-nCoV infection in vitro.
T116 938-1024 Sentence denotes These antiviral compounds have been used in human patients with a safety track record.
T117 1025-1107 Sentence denotes Thus, these therapeutic agents can be considered to treat COVID-19 infection [27].
T118 1108-1183 Sentence denotes Furthermore, there are a number of other compounds that are in development.
T119 1184-1444 Sentence denotes These include the clinical candidate EIDD-2801 compound that has shown high therapeutic potential aganist seasonal and pandemic influenza virus infections and this represents another potential drug to be considered for the treatment of COVID-19 infection [28].
T120 1445-1729 Sentence denotes Along those lines, until more specific therapeutics become available, it is reasonable to consider more broad-spectrum antivirals that provide drug treatment options for COVID-19 infection include Lopinavir/Ritonavir, Neuraminidase inhibitors, peptide (EK1), RNA synthesis inhibitors.
T121 1730-1863 Sentence denotes It is clear however, that more research is urgently needed to identify novel chemotherapeutic drugs for treating COVID-19 infections.
T122 1864-2050 Sentence denotes In order to develop pre-and post-exposure prophylaxis against COVID-19, there is an urgent need to establish an animal model to replicate the severe disease currently observed in humans.
T123 2051-2331 Sentence denotes Several groups of scientists are currently working hard to develop a nonhuman primate model to study COVID-19 infection to establish fast track novel therapeutics and for the testing of potential vaccines in addition to providing a better understanding of virus-host interactions.

2_test

Id Subject Object Predicate Lexical cue
32113704-32007143-55638578 781-783 32007143 denotes 26
32113704-32007143-55638578 781-783 32007143 denotes 26

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
572 1663-1676 Gene denotes Neuraminidase Gene:4758
573 80-88 Species denotes patients Tax:9606
574 250-256 Species denotes humans Tax:9606
575 533-541 Species denotes patients Tax:9606
576 982-987 Species denotes human Tax:9606
577 988-996 Species denotes patients Tax:9606
578 2043-2049 Species denotes humans Tax:9606
579 329-339 Chemical denotes Nucleoside MESH:D009705
580 661-672 Chemical denotes oseltamivir MESH:D053139
581 681-690 Chemical denotes lopinavir MESH:D061466
582 699-708 Chemical denotes ritonavir MESH:D019438
583 754-765 Chemical denotes ganciclovir MESH:D015774
584 842-852 Chemical denotes remdesivir MESH:C000606551
585 857-868 Chemical denotes chloroquine MESH:D002738
586 1642-1661 Chemical denotes Lopinavir/Ritonavir MESH:C558899
587 37-45 Disease denotes COVID-19 MESH:C000657245
588 46-55 Disease denotes infection MESH:D007239
589 206-214 Disease denotes COVID-19 MESH:C000657245
590 215-224 Disease denotes infection MESH:D007239
591 410-419 Disease denotes infection MESH:D007239
592 908-927 Disease denotes 2019-nCoV infection MESH:C000657245
593 1083-1091 Disease denotes COVID-19 MESH:C000657245
594 1092-1101 Disease denotes infection MESH:D007239
595 1322-1338 Disease denotes virus infections MESH:D001102
596 1420-1428 Disease denotes COVID-19 MESH:C000657245
597 1429-1438 Disease denotes infection MESH:D007239
598 1615-1623 Disease denotes COVID-19 MESH:C000657245
599 1624-1633 Disease denotes infection MESH:D007239
600 1843-1851 Disease denotes COVID-19 MESH:C000657245
601 1852-1862 Disease denotes infections MESH:D007239
602 1926-1934 Disease denotes COVID-19 MESH:C000657245
603 2006-2020 Disease denotes severe disease MESH:D045169
604 2152-2160 Disease denotes COVID-19 MESH:C000657245
605 2161-2170 Disease denotes infection MESH:D007239