PMC:7126544 / 43446-43722 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7126544","sourcedb":"PMC","sourceid":"7126544","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7126544","text":" Viroporin 3a triggered the activation of the NLRP3 inflammasome and the secretion of IL-1β in bone marrow-derived macrophages, suggesting SARS-CoV induced cell pyroptosis [89]. Studies have shown that patients infected with SARS-CoV-2 have increased IL-1β in the serum [26]. ","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T96","span":{"begin":86,"end":90},"obj":"Body_part"},{"id":"T97","span":{"begin":95,"end":106},"obj":"Body_part"},{"id":"T98","span":{"begin":115,"end":126},"obj":"Body_part"},{"id":"T99","span":{"begin":156,"end":160},"obj":"Body_part"},{"id":"T100","span":{"begin":251,"end":255},"obj":"Body_part"},{"id":"T101","span":{"begin":264,"end":269},"obj":"Body_part"}],"attributes":[{"id":"A96","pred":"fma_id","subj":"T96","obj":"http://purl.org/sig/ont/fma/fma86583"},{"id":"A97","pred":"fma_id","subj":"T97","obj":"http://purl.org/sig/ont/fma/fma9608"},{"id":"A98","pred":"fma_id","subj":"T98","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A99","pred":"fma_id","subj":"T99","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A100","pred":"fma_id","subj":"T100","obj":"http://purl.org/sig/ont/fma/fma86583"},{"id":"A101","pred":"fma_id","subj":"T101","obj":"http://purl.org/sig/ont/fma/fma63083"},{"subj":"T96","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T97","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T98","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T99","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T100","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T101","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T54","span":{"begin":95,"end":106},"obj":"Body_part"},{"id":"T55","span":{"begin":264,"end":269},"obj":"Body_part"}],"attributes":[{"id":"A54","pred":"uberon_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/UBERON_0002371"},{"id":"A55","pred":"uberon_id","subj":"T55","obj":"http://purl.obolibrary.org/obo/UBERON_0001977"},{"subj":"T54","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T55","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid_AGAC","denotations":[{"id":"p84058s13","span":{"begin":241,"end":250},"obj":"PosReg"},{"id":"p84058s14","span":{"begin":251,"end":253},"obj":"MPA"},{"id":"p84058s15","span":{"begin":253,"end":256},"obj":"MPA"}],"attributes":[{"subj":"p84058s13","pred":"source","obj":"LitCovid_AGAC"},{"subj":"p84058s14","pred":"source","obj":"LitCovid_AGAC"},{"subj":"p84058s15","pred":"source","obj":"LitCovid_AGAC"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T364","span":{"begin":139,"end":147},"obj":"Disease"},{"id":"T365","span":{"begin":139,"end":143},"obj":"Disease"},{"id":"T366","span":{"begin":225,"end":233},"obj":"Disease"},{"id":"T367","span":{"begin":225,"end":229},"obj":"Disease"}],"attributes":[{"id":"A364","pred":"mondo_id","subj":"T364","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A365","pred":"mondo_id","subj":"T365","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A366","pred":"mondo_id","subj":"T366","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A367","pred":"mondo_id","subj":"T367","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T364","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T365","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T366","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T367","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T351","span":{"begin":28,"end":38},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T352","span":{"begin":95,"end":99},"obj":"http://purl.obolibrary.org/obo/UBERON_0002481"},{"id":"T353","span":{"begin":156,"end":160},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"attributes":[{"subj":"T351","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T352","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T353","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T88","span":{"begin":86,"end":88},"obj":"Chemical"},{"id":"T90","span":{"begin":251,"end":253},"obj":"Chemical"}],"attributes":[{"id":"A88","pred":"chebi_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A89","pred":"chebi_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A90","pred":"chebi_id","subj":"T90","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A91","pred":"chebi_id","subj":"T90","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"subj":"T88","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T90","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T32","span":{"begin":1,"end":10},"obj":"http://purl.obolibrary.org/obo/GO_0039707"},{"id":"T33","span":{"begin":73,"end":82},"obj":"http://purl.obolibrary.org/obo/GO_0046903"},{"id":"T34","span":{"begin":161,"end":171},"obj":"http://purl.obolibrary.org/obo/GO_0070269"}],"attributes":[{"subj":"T32","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T33","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T34","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T368","span":{"begin":178,"end":275},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T368","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"1192","span":{"begin":46,"end":51},"obj":"Gene"},{"id":"1193","span":{"begin":86,"end":91},"obj":"Gene"},{"id":"1194","span":{"begin":251,"end":256},"obj":"Gene"},{"id":"1203","span":{"begin":139,"end":147},"obj":"Species"},{"id":"1204","span":{"begin":202,"end":210},"obj":"Species"},{"id":"1205","span":{"begin":225,"end":235},"obj":"Species"},{"id":"1211","span":{"begin":211,"end":219},"obj":"Disease"}],"attributes":[{"id":"A1192","pred":"tao:has_database_id","subj":"1192","obj":"Gene:114548"},{"id":"A1193","pred":"tao:has_database_id","subj":"1193","obj":"Gene:3552"},{"id":"A1194","pred":"tao:has_database_id","subj":"1194","obj":"Gene:3552"},{"id":"A1203","pred":"tao:has_database_id","subj":"1203","obj":"Tax:694009"},{"id":"A1204","pred":"tao:has_database_id","subj":"1204","obj":"Tax:9606"},{"id":"A1205","pred":"tao:has_database_id","subj":"1205","obj":"Tax:2697049"},{"id":"A1211","pred":"tao:has_database_id","subj":"1211","obj":"MESH:D007239"},{"subj":"1192","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1193","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1194","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1203","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1204","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1205","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1211","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"2_test","denotations":[{"id":"32143990-30761102-55637414","span":{"begin":173,"end":175},"obj":"30761102"},{"id":"32143990-31986264-55637415","span":{"begin":271,"end":273},"obj":"31986264"}],"attributes":[{"subj":"32143990-30761102-55637414","pred":"source","obj":"2_test"},{"subj":"32143990-31986264-55637415","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#93ec97","default":true},{"id":"LitCovid-PD-UBERON","color":"#ec93a8"},{"id":"LitCovid_AGAC","color":"#93c2ec"},{"id":"LitCovid-PD-MONDO","color":"#dcec93"},{"id":"LitCovid-PD-CLO","color":"#e293ec"},{"id":"LitCovid-PD-CHEBI","color":"#93ecc8"},{"id":"LitCovid-PD-GO-BP","color":"#ecae93"},{"id":"LitCovid-sentences","color":"#9493ec"},{"id":"LitCovid-PubTator","color":"#acec93"},{"id":"2_test","color":"#ec93c6"}]}]}}