PMC:7126544 / 2077-3034 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7126544","sourcedb":"PMC","sourceid":"7126544","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7126544","text":"•The 2019-nCoV is officially called SARS-CoV-2, and is the cause of the disease named COVID-19.\n•COVID-19 is the third severe epidemic caused by coronaviruses in the past 20 years.\n•It is believed that the SARS-CoV-2 virus originated from bats, based on genomic sequencing.\n•While human strains of Coronavirus are associated with about 15% of cases of the common cold, the SARS-CoV-2 is far more deadly, with a mortality rate around 2.3%.\n•As of February 19th, 2020, there have been 75,282 confirmed cases and 2012 deaths worldwide.\n•Lessons learned from SARS in 2003 resulted in faster determination of the nucleic acid sequence and a more robust quarantine strategy.\n•Extreme quarantine measures, including sealing off large cities, closing borders and confining people to their homes are critical to stemming spread of the virus.\n•Pyroptosis, a novel form of inflammatory cell death, is a possible mechanism for the increased virulence of the 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