PMC:7126544 / 20045-21589 JSONTXT

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    LitCovid-PD-FMA-UBERON

    {"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T33","span":{"begin":922,"end":925},"obj":"Body_part"},{"id":"T35","span":{"begin":1287,"end":1291},"obj":"Body_part"}],"attributes":[{"id":"A33","pred":"fma_id","subj":"T33","obj":"http://purl.org/sig/ont/fma/fma13443"},{"id":"A34","pred":"fma_id","subj":"T33","obj":"http://purl.org/sig/ont/fma/fma68615"},{"id":"A35","pred":"fma_id","subj":"T35","obj":"http://purl.org/sig/ont/fma/fma46495"}],"text":"5.1 The origin of SARS-CoV-2\nA cluster of cases of viral pneumonia of unknown etiology, now known as SARS-CoV-2 pneumonia, occurred in Wuhan, Hubei Province and were reported to health authorities on the December 29, 2019 [60]. This outbreak was associated with a large seafood and animal market [61]. Further investigations are ongoing to determine the origin of the infection. To date, many reports have described possible original and intermediate hosts (Fig. 1 ). Researchers found that the SARS-CoV-2 showed a higher sequence homology to Bat-CoV-RaTG13 that was previously detected in Rhinolophus affinis from Yunnan Province than Bat-SL-CoVZC21 and Bat-SL-CoVZC45, which suggested that the Chinese chrysanthemum bat is the origin of SARS-CoV-2. More recently, the pangolin was believed to be the likely intermediate host due to the fact that there appeared to be approximately 99% sequence homology between SARS-Co V-2 and the consensus sequence derived from \u003e1000 metagenomic samples from the pangolin species [62].\nFig. 1 The origin and inter-host timeline of SARS-CoV-2. All the information is derived from published data. Journal name: (a) Emerging Microbes \u0026 Infections, (b) bioRvix, (c) J Med Virol, (d) The Lancet, (e) the New England Journal of Medicine, (f) J Virol, (g) Chin Med J (Engl), (h) https://www.scau.edu.cn/2020/0207/c1300a219015/page.htm. Bat-ZC21: Bat-SL-CoVZC21, GenBank Accession MG772934; Bat-ZC45: Bat-SL-CoVZC45, GenBank Accession MG772933; Bat-RaTG13: yun-nan-Bat-CoV-RaTG13, GISAID accession EPI_ISL_402,131."}

    LitCovid-PD-UBERON

    {"project":"LitCovid-PD-UBERON","denotations":[{"id":"T14","span":{"begin":1287,"end":1291},"obj":"Body_part"}],"attributes":[{"id":"A14","pred":"uberon_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/UBERON_0008199"}],"text":"5.1 The origin of SARS-CoV-2\nA cluster of cases of viral pneumonia of unknown etiology, now known as SARS-CoV-2 pneumonia, occurred in Wuhan, Hubei Province and were reported to health authorities on the December 29, 2019 [60]. This outbreak was associated with a large seafood and animal market [61]. Further investigations are ongoing to determine the origin of the infection. To date, many reports have described possible original and intermediate hosts (Fig. 1 ). Researchers found that the SARS-CoV-2 showed a higher sequence homology to Bat-CoV-RaTG13 that was previously detected in Rhinolophus affinis from Yunnan Province than Bat-SL-CoVZC21 and Bat-SL-CoVZC45, which suggested that the Chinese chrysanthemum bat is the origin of SARS-CoV-2. More recently, the pangolin was believed to be the likely intermediate host due to the fact that there appeared to be approximately 99% sequence homology between SARS-Co V-2 and the consensus sequence derived from \u003e1000 metagenomic samples from the pangolin species [62].\nFig. 1 The origin and inter-host timeline of SARS-CoV-2. All the information is derived from published data. Journal name: (a) Emerging Microbes \u0026 Infections, (b) bioRvix, (c) J Med Virol, (d) The Lancet, (e) the New England Journal of Medicine, (f) J Virol, (g) Chin Med J (Engl), (h) https://www.scau.edu.cn/2020/0207/c1300a219015/page.htm. Bat-ZC21: Bat-SL-CoVZC21, GenBank Accession MG772934; Bat-ZC45: Bat-SL-CoVZC45, GenBank Accession MG772933; Bat-RaTG13: yun-nan-Bat-CoV-RaTG13, GISAID accession EPI_ISL_402,131."}

    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T160","span":{"begin":19,"end":27},"obj":"Disease"},{"id":"T161","span":{"begin":19,"end":23},"obj":"Disease"},{"id":"T162","span":{"begin":52,"end":67},"obj":"Disease"},{"id":"T163","span":{"begin":58,"end":67},"obj":"Disease"},{"id":"T164","span":{"begin":102,"end":110},"obj":"Disease"},{"id":"T165","span":{"begin":102,"end":106},"obj":"Disease"},{"id":"T166","span":{"begin":113,"end":122},"obj":"Disease"},{"id":"T167","span":{"begin":369,"end":378},"obj":"Disease"},{"id":"T168","span":{"begin":496,"end":504},"obj":"Disease"},{"id":"T169","span":{"begin":496,"end":500},"obj":"Disease"},{"id":"T170","span":{"begin":740,"end":748},"obj":"Disease"},{"id":"T171","span":{"begin":740,"end":744},"obj":"Disease"},{"id":"T172","span":{"begin":914,"end":918},"obj":"Disease"},{"id":"T173","span":{"begin":1069,"end":1077},"obj":"Disease"},{"id":"T174","span":{"begin":1069,"end":1073},"obj":"Disease"}],"attributes":[{"id":"A160","pred":"mondo_id","subj":"T160","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A161","pred":"mondo_id","subj":"T161","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A162","pred":"mondo_id","subj":"T162","obj":"http://purl.obolibrary.org/obo/MONDO_0006012"},{"id":"A163","pred":"mondo_id","subj":"T163","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A164","pred":"mondo_id","subj":"T164","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A165","pred":"mondo_id","subj":"T165","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A166","pred":"mondo_id","subj":"T166","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A167","pred":"mondo_id","subj":"T167","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A168","pred":"mondo_id","subj":"T168","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A169","pred":"mondo_id","subj":"T169","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A170","pred":"mondo_id","subj":"T170","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A171","pred":"mondo_id","subj":"T171","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A172","pred":"mondo_id","subj":"T172","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A173","pred":"mondo_id","subj":"T173","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A174","pred":"mondo_id","subj":"T174","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"5.1 The origin of SARS-CoV-2\nA cluster of cases of viral pneumonia of unknown etiology, now known as SARS-CoV-2 pneumonia, occurred in Wuhan, Hubei Province and were reported to health authorities on the December 29, 2019 [60]. This outbreak was associated with a large seafood and animal market [61]. Further investigations are ongoing to determine the origin of the infection. To date, many reports have described possible original and intermediate hosts (Fig. 1 ). Researchers found that the SARS-CoV-2 showed a higher sequence homology to Bat-CoV-RaTG13 that was previously detected in Rhinolophus affinis from Yunnan Province than Bat-SL-CoVZC21 and Bat-SL-CoVZC45, which suggested that the Chinese chrysanthemum bat is the origin of SARS-CoV-2. More recently, the pangolin was believed to be the likely intermediate host due to the fact that there appeared to be approximately 99% sequence homology between SARS-Co V-2 and the consensus sequence derived from \u003e1000 metagenomic samples from the pangolin species [62].\nFig. 1 The origin and inter-host timeline of SARS-CoV-2. All the information is derived from published data. Journal name: (a) Emerging Microbes \u0026 Infections, (b) bioRvix, (c) J Med Virol, (d) The Lancet, (e) the New England Journal of Medicine, (f) J Virol, (g) Chin Med J (Engl), (h) https://www.scau.edu.cn/2020/0207/c1300a219015/page.htm. Bat-ZC21: Bat-SL-CoVZC21, GenBank Accession MG772934; Bat-ZC45: Bat-SL-CoVZC45, GenBank Accession MG772933; Bat-RaTG13: yun-nan-Bat-CoV-RaTG13, GISAID accession EPI_ISL_402,131."}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T170","span":{"begin":30,"end":31},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T171","span":{"begin":263,"end":264},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T172","span":{"begin":283,"end":289},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_33208"},{"id":"T173","span":{"begin":514,"end":515},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T174","span":{"begin":719,"end":725},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9397"},{"id":"T175","span":{"begin":1148,"end":1149},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T176","span":{"begin":1184,"end":1185},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"}],"text":"5.1 The origin of SARS-CoV-2\nA cluster of cases of viral pneumonia of unknown etiology, now known as SARS-CoV-2 pneumonia, occurred in Wuhan, Hubei Province and were reported to health authorities on the December 29, 2019 [60]. This outbreak was associated with a large seafood and animal market [61]. Further investigations are ongoing to determine the origin of the infection. To date, many reports have described possible original and intermediate hosts (Fig. 1 ). Researchers found that the SARS-CoV-2 showed a higher sequence homology to Bat-CoV-RaTG13 that was previously detected in Rhinolophus affinis from Yunnan Province than Bat-SL-CoVZC21 and Bat-SL-CoVZC45, which suggested that the Chinese chrysanthemum bat is the origin of SARS-CoV-2. More recently, the pangolin was believed to be the likely intermediate host due to the fact that there appeared to be approximately 99% sequence homology between SARS-Co V-2 and the consensus sequence derived from \u003e1000 metagenomic samples from the pangolin species [62].\nFig. 1 The origin and inter-host timeline of SARS-CoV-2. All the information is derived from published data. Journal name: (a) Emerging Microbes \u0026 Infections, (b) bioRvix, (c) J Med Virol, (d) The Lancet, (e) the New England Journal of Medicine, (f) J Virol, (g) Chin Med J (Engl), (h) https://www.scau.edu.cn/2020/0207/c1300a219015/page.htm. Bat-ZC21: Bat-SL-CoVZC21, GenBank Accession MG772934; Bat-ZC45: Bat-SL-CoVZC45, GenBank Accession MG772933; Bat-RaTG13: yun-nan-Bat-CoV-RaTG13, GISAID accession EPI_ISL_402,131."}

    LitCovid-PD-CHEBI

    {"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T29","span":{"begin":641,"end":643},"obj":"Chemical"},{"id":"T30","span":{"begin":660,"end":662},"obj":"Chemical"},{"id":"T31","span":{"begin":919,"end":921},"obj":"Chemical"},{"id":"T32","span":{"begin":1381,"end":1383},"obj":"Chemical"},{"id":"T33","span":{"begin":1435,"end":1437},"obj":"Chemical"}],"attributes":[{"id":"A29","pred":"chebi_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_74815"},{"id":"A30","pred":"chebi_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/CHEBI_74815"},{"id":"A31","pred":"chebi_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/CHEBI_27638"},{"id":"A32","pred":"chebi_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_74815"},{"id":"A33","pred":"chebi_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/CHEBI_74815"}],"text":"5.1 The origin of SARS-CoV-2\nA cluster of cases of viral pneumonia of unknown etiology, now known as SARS-CoV-2 pneumonia, occurred in Wuhan, Hubei Province and were reported to health authorities on the December 29, 2019 [60]. This outbreak was associated with a large seafood and animal market [61]. Further investigations are ongoing to determine the origin of the infection. To date, many reports have described possible original and intermediate hosts (Fig. 1 ). Researchers found that the SARS-CoV-2 showed a higher sequence homology to Bat-CoV-RaTG13 that was previously detected in Rhinolophus affinis from Yunnan Province than Bat-SL-CoVZC21 and Bat-SL-CoVZC45, which suggested that the Chinese chrysanthemum bat is the origin of SARS-CoV-2. More recently, the pangolin was believed to be the likely intermediate host due to the fact that there appeared to be approximately 99% sequence homology between SARS-Co V-2 and the consensus sequence derived from \u003e1000 metagenomic samples from the pangolin species [62].\nFig. 1 The origin and inter-host timeline of SARS-CoV-2. All the information is derived from published data. Journal name: (a) Emerging Microbes \u0026 Infections, (b) bioRvix, (c) J Med Virol, (d) The Lancet, (e) the New England Journal of Medicine, (f) J Virol, (g) Chin Med J (Engl), (h) https://www.scau.edu.cn/2020/0207/c1300a219015/page.htm. Bat-ZC21: Bat-SL-CoVZC21, GenBank Accession MG772934; Bat-ZC45: Bat-SL-CoVZC45, GenBank Accession MG772933; Bat-RaTG13: yun-nan-Bat-CoV-RaTG13, GISAID accession EPI_ISL_402,131."}

    LitCovid-PD-HP

    {"project":"LitCovid-PD-HP","denotations":[{"id":"T17","span":{"begin":58,"end":67},"obj":"Phenotype"},{"id":"T18","span":{"begin":113,"end":122},"obj":"Phenotype"}],"attributes":[{"id":"A17","pred":"hp_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A18","pred":"hp_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"5.1 The origin of SARS-CoV-2\nA cluster of cases of viral pneumonia of unknown etiology, now known as SARS-CoV-2 pneumonia, occurred in Wuhan, Hubei Province and were reported to health authorities on the December 29, 2019 [60]. This outbreak was associated with a large seafood and animal market [61]. Further investigations are ongoing to determine the origin of the infection. To date, many reports have described possible original and intermediate hosts (Fig. 1 ). Researchers found that the SARS-CoV-2 showed a higher sequence homology to Bat-CoV-RaTG13 that was previously detected in Rhinolophus affinis from Yunnan Province than Bat-SL-CoVZC21 and Bat-SL-CoVZC45, which suggested that the Chinese chrysanthemum bat is the origin of SARS-CoV-2. More recently, the pangolin was believed to be the likely intermediate host due to the fact that there appeared to be approximately 99% sequence homology between SARS-Co V-2 and the consensus sequence derived from \u003e1000 metagenomic samples from the pangolin species [62].\nFig. 1 The origin and inter-host timeline of SARS-CoV-2. All the information is derived from published data. Journal name: (a) Emerging Microbes \u0026 Infections, (b) bioRvix, (c) J Med Virol, (d) The Lancet, (e) the New England Journal of Medicine, (f) J Virol, (g) Chin Med J (Engl), (h) https://www.scau.edu.cn/2020/0207/c1300a219015/page.htm. Bat-ZC21: Bat-SL-CoVZC21, GenBank Accession MG772934; Bat-ZC45: Bat-SL-CoVZC45, GenBank Accession MG772933; Bat-RaTG13: yun-nan-Bat-CoV-RaTG13, GISAID accession EPI_ISL_402,131."}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T173","span":{"begin":0,"end":29},"obj":"Sentence"},{"id":"T174","span":{"begin":30,"end":228},"obj":"Sentence"},{"id":"T175","span":{"begin":229,"end":302},"obj":"Sentence"},{"id":"T176","span":{"begin":303,"end":379},"obj":"Sentence"},{"id":"T177","span":{"begin":380,"end":468},"obj":"Sentence"},{"id":"T178","span":{"begin":469,"end":751},"obj":"Sentence"},{"id":"T179","span":{"begin":752,"end":1023},"obj":"Sentence"},{"id":"T180","span":{"begin":1024,"end":1080},"obj":"Sentence"},{"id":"T181","span":{"begin":1081,"end":1132},"obj":"Sentence"},{"id":"T182","span":{"begin":1133,"end":1366},"obj":"Sentence"},{"id":"T183","span":{"begin":1367,"end":1376},"obj":"Sentence"},{"id":"T184","span":{"begin":1377,"end":1430},"obj":"Sentence"},{"id":"T185","span":{"begin":1431,"end":1544},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"5.1 The origin of SARS-CoV-2\nA cluster of cases of viral pneumonia of unknown etiology, now known as SARS-CoV-2 pneumonia, occurred in Wuhan, Hubei Province and were reported to health authorities on the December 29, 2019 [60]. This outbreak was associated with a large seafood and animal market [61]. Further investigations are ongoing to determine the origin of the infection. To date, many reports have described possible original and intermediate hosts (Fig. 1 ). Researchers found that the SARS-CoV-2 showed a higher sequence homology to Bat-CoV-RaTG13 that was previously detected in Rhinolophus affinis from Yunnan Province than Bat-SL-CoVZC21 and Bat-SL-CoVZC45, which suggested that the Chinese chrysanthemum bat is the origin of SARS-CoV-2. More recently, the pangolin was believed to be the likely intermediate host due to the fact that there appeared to be approximately 99% sequence homology between SARS-Co V-2 and the consensus sequence derived from \u003e1000 metagenomic samples from the pangolin species [62].\nFig. 1 The origin and inter-host timeline of SARS-CoV-2. All the information is derived from published data. Journal name: (a) Emerging Microbes \u0026 Infections, (b) bioRvix, (c) J Med Virol, (d) The Lancet, (e) the New England Journal of Medicine, (f) J Virol, (g) Chin Med J (Engl), (h) https://www.scau.edu.cn/2020/0207/c1300a219015/page.htm. Bat-ZC21: Bat-SL-CoVZC21, GenBank Accession MG772934; Bat-ZC45: Bat-SL-CoVZC45, GenBank Accession MG772933; Bat-RaTG13: yun-nan-Bat-CoV-RaTG13, GISAID accession EPI_ISL_402,131."}

    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"432","span":{"begin":1299,"end":1303},"obj":"Gene"},{"id":"433","span":{"begin":1069,"end":1079},"obj":"Species"},{"id":"434","span":{"begin":1499,"end":1502},"obj":"Species"},{"id":"435","span":{"begin":1171,"end":1181},"obj":"Disease"},{"id":"444","span":{"begin":496,"end":506},"obj":"Species"},{"id":"445","span":{"begin":548,"end":551},"obj":"Species"},{"id":"446","span":{"begin":591,"end":610},"obj":"Species"},{"id":"447","span":{"begin":740,"end":750},"obj":"Species"},{"id":"448","span":{"begin":914,"end":925},"obj":"Species"},{"id":"449","span":{"begin":52,"end":67},"obj":"Disease"},{"id":"450","span":{"begin":102,"end":122},"obj":"Disease"},{"id":"451","span":{"begin":369,"end":378},"obj":"Disease"}],"attributes":[{"id":"A432","pred":"tao:has_database_id","subj":"432","obj":"Gene:9941"},{"id":"A433","pred":"tao:has_database_id","subj":"433","obj":"Tax:2697049"},{"id":"A434","pred":"tao:has_database_id","subj":"434","obj":"Tax:11118"},{"id":"A435","pred":"tao:has_database_id","subj":"435","obj":"MESH:D007239"},{"id":"A444","pred":"tao:has_database_id","subj":"444","obj":"Tax:2697049"},{"id":"A445","pred":"tao:has_database_id","subj":"445","obj":"Tax:11118"},{"id":"A446","pred":"tao:has_database_id","subj":"446","obj":"Tax:59477"},{"id":"A447","pred":"tao:has_database_id","subj":"447","obj":"Tax:2697049"},{"id":"A448","pred":"tao:has_database_id","subj":"448","obj":"Tax:2697049"},{"id":"A450","pred":"tao:has_database_id","subj":"450","obj":"MESH:C000657245"},{"id":"A451","pred":"tao:has_database_id","subj":"451","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"5.1 The origin of SARS-CoV-2\nA cluster of cases of viral pneumonia of unknown etiology, now known as SARS-CoV-2 pneumonia, occurred in Wuhan, Hubei Province and were reported to health authorities on the December 29, 2019 [60]. This outbreak was associated with a large seafood and animal market [61]. Further investigations are ongoing to determine the origin of the infection. To date, many reports have described possible original and intermediate hosts (Fig. 1 ). Researchers found that the SARS-CoV-2 showed a higher sequence homology to Bat-CoV-RaTG13 that was previously detected in Rhinolophus affinis from Yunnan Province than Bat-SL-CoVZC21 and Bat-SL-CoVZC45, which suggested that the Chinese chrysanthemum bat is the origin of SARS-CoV-2. More recently, the pangolin was believed to be the likely intermediate host due to the fact that there appeared to be approximately 99% sequence homology between SARS-Co V-2 and the consensus sequence derived from \u003e1000 metagenomic samples from the pangolin species [62].\nFig. 1 The origin and inter-host timeline of SARS-CoV-2. All the information is derived from published data. Journal name: (a) Emerging Microbes \u0026 Infections, (b) bioRvix, (c) J Med Virol, (d) The Lancet, (e) the New England Journal of Medicine, (f) J Virol, (g) Chin Med J (Engl), (h) https://www.scau.edu.cn/2020/0207/c1300a219015/page.htm. Bat-ZC21: Bat-SL-CoVZC21, GenBank Accession MG772934; Bat-ZC45: Bat-SL-CoVZC45, GenBank Accession MG772933; Bat-RaTG13: yun-nan-Bat-CoV-RaTG13, GISAID accession EPI_ISL_402,131."}