PMC:7121452 / 2451-3387 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7121452","sourcedb":"PMC","sourceid":"7121452","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7121452","text":"Coexisting conditions, including hypertension, have consistently been reported to be more common among patients with Covid-19 who have had severe illness, been admitted to the intensive care unit, received mechanical ventilation, or died than among patients who have had mild illness. There are concerns that medical management of these coexisting conditions, including the use of RAAS inhibitors, may have contributed to the adverse health outcomes observed. However, these conditions appear to track closely with advancing age,13 which is emerging as the strongest predictor of Covid-19–related death.14 Unfortunately, reports to date have not rigorously accounted for age or other key factors that contribute to health as potential confounders in risk prediction. With other infective illnesses, coexisting conditions such as hypertension have been key prognostic determinants,10 and this also appears to be the case with Covid-19.15","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"85","span":{"begin":103,"end":111},"obj":"Species"},{"id":"86","span":{"begin":249,"end":257},"obj":"Species"},{"id":"87","span":{"begin":33,"end":45},"obj":"Disease"},{"id":"88","span":{"begin":117,"end":125},"obj":"Disease"},{"id":"89","span":{"begin":233,"end":237},"obj":"Disease"},{"id":"90","span":{"begin":580,"end":588},"obj":"Disease"},{"id":"91","span":{"begin":597,"end":602},"obj":"Disease"},{"id":"92","span":{"begin":829,"end":841},"obj":"Disease"},{"id":"93","span":{"begin":925,"end":933},"obj":"Disease"}],"attributes":[{"id":"A85","pred":"tao:has_database_id","subj":"85","obj":"Tax:9606"},{"id":"A86","pred":"tao:has_database_id","subj":"86","obj":"Tax:9606"},{"id":"A87","pred":"tao:has_database_id","subj":"87","obj":"MESH:D006973"},{"id":"A88","pred":"tao:has_database_id","subj":"88","obj":"MESH:C000657245"},{"id":"A89","pred":"tao:has_database_id","subj":"89","obj":"MESH:D003643"},{"id":"A90","pred":"tao:has_database_id","subj":"90","obj":"MESH:C000657245"},{"id":"A91","pred":"tao:has_database_id","subj":"91","obj":"MESH:D003643"},{"id":"A92","pred":"tao:has_database_id","subj":"92","obj":"MESH:D006973"},{"id":"A93","pred":"tao:has_database_id","subj":"93","obj":"MESH:C000657245"},{"subj":"85","pred":"source","obj":"LitCovid-PubTator"},{"subj":"86","pred":"source","obj":"LitCovid-PubTator"},{"subj":"87","pred":"source","obj":"LitCovid-PubTator"},{"subj":"88","pred":"source","obj":"LitCovid-PubTator"},{"subj":"89","pred":"source","obj":"LitCovid-PubTator"},{"subj":"90","pred":"source","obj":"LitCovid-PubTator"},{"subj":"91","pred":"source","obj":"LitCovid-PubTator"},{"subj":"92","pred":"source","obj":"LitCovid-PubTator"},{"subj":"93","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T12","span":{"begin":33,"end":45},"obj":"Disease"},{"id":"T13","span":{"begin":829,"end":841},"obj":"Disease"}],"attributes":[{"id":"A12","pred":"mondo_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/MONDO_0005044"},{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0005044"},{"subj":"T12","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T13","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T16","span":{"begin":386,"end":396},"obj":"Chemical"}],"attributes":[{"id":"A16","pred":"chebi_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"subj":"T16","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T4","span":{"begin":33,"end":45},"obj":"Phenotype"},{"id":"T5","span":{"begin":829,"end":841},"obj":"Phenotype"}],"attributes":[{"id":"A4","pred":"hp_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/HP_0000822"},{"id":"A5","pred":"hp_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/HP_0000822"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T5","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T11","span":{"begin":0,"end":284},"obj":"Sentence"},{"id":"T12","span":{"begin":285,"end":459},"obj":"Sentence"},{"id":"T13","span":{"begin":460,"end":766},"obj":"Sentence"},{"id":"T14","span":{"begin":767,"end":936},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T11","pred":"source","obj":"LitCovid-sentences"},{"subj":"T12","pred":"source","obj":"LitCovid-sentences"},{"subj":"T13","pred":"source","obj":"LitCovid-sentences"},{"subj":"T14","pred":"source","obj":"LitCovid-sentences"}]},{"project":"2_test","denotations":[{"id":"32227760-32171076-75177408","span":{"begin":603,"end":605},"obj":"32171076"},{"id":"32227760-31333767-75177409","span":{"begin":880,"end":882},"obj":"31333767"},{"id":"32227760-32173574-75177410","span":{"begin":934,"end":936},"obj":"32173574"}],"attributes":[{"subj":"32227760-32171076-75177408","pred":"source","obj":"2_test"},{"subj":"32227760-31333767-75177409","pred":"source","obj":"2_test"},{"subj":"32227760-32173574-75177410","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#ec93a2","default":true},{"id":"LitCovid-PD-MONDO","color":"#93bcec"},{"id":"LitCovid-PD-CHEBI","color":"#d6ec93"},{"id":"LitCovid-PD-HP","color":"#e893ec"},{"id":"LitCovid-sentences","color":"#93ecce"},{"id":"2_test","color":"#ecb393"}]}]}}