PMC:7121452 / 14858-15523 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7121452","sourcedb":"PMC","sourceid":"7121452","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7121452","text":"The effects of withdrawing RAAS inhibitors or switching treatments are uncertain among patients with chronic kidney disease. Although reported rates of chronic kidney disease appear to be low among hospitalized patients with Covid-19 in China (1 to 3%) (Table S1), the prevalence may be higher among patients who are critically ill and among those in other geographic regions.59 Many patients have varying degrees of acute kidney injury during illness.14,67,68 For these high-risk patients, individualized treatment decisions regarding the maintenance of RAAS inhibitors that are guided by hemodynamic status, renal function, and clinical stability are recommended.","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"466","span":{"begin":87,"end":95},"obj":"Species"},{"id":"467","span":{"begin":211,"end":219},"obj":"Species"},{"id":"468","span":{"begin":300,"end":308},"obj":"Species"},{"id":"469","span":{"begin":384,"end":392},"obj":"Species"},{"id":"470","span":{"begin":481,"end":489},"obj":"Species"},{"id":"471","span":{"begin":101,"end":123},"obj":"Disease"},{"id":"472","span":{"begin":160,"end":174},"obj":"Disease"},{"id":"473","span":{"begin":225,"end":233},"obj":"Disease"},{"id":"474","span":{"begin":317,"end":331},"obj":"Disease"},{"id":"475","span":{"begin":417,"end":436},"obj":"Disease"}],"attributes":[{"id":"A466","pred":"tao:has_database_id","subj":"466","obj":"Tax:9606"},{"id":"A467","pred":"tao:has_database_id","subj":"467","obj":"Tax:9606"},{"id":"A468","pred":"tao:has_database_id","subj":"468","obj":"Tax:9606"},{"id":"A469","pred":"tao:has_database_id","subj":"469","obj":"Tax:9606"},{"id":"A470","pred":"tao:has_database_id","subj":"470","obj":"Tax:9606"},{"id":"A471","pred":"tao:has_database_id","subj":"471","obj":"MESH:D051436"},{"id":"A472","pred":"tao:has_database_id","subj":"472","obj":"MESH:D007674"},{"id":"A473","pred":"tao:has_database_id","subj":"473","obj":"MESH:C000657245"},{"id":"A474","pred":"tao:has_database_id","subj":"474","obj":"MESH:D016638"},{"id":"A475","pred":"tao:has_database_id","subj":"475","obj":"MESH:D058186"},{"subj":"466","pred":"source","obj":"LitCovid-PubTator"},{"subj":"467","pred":"source","obj":"LitCovid-PubTator"},{"subj":"468","pred":"source","obj":"LitCovid-PubTator"},{"subj":"469","pred":"source","obj":"LitCovid-PubTator"},{"subj":"470","pred":"source","obj":"LitCovid-PubTator"},{"subj":"471","pred":"source","obj":"LitCovid-PubTator"},{"subj":"472","pred":"source","obj":"LitCovid-PubTator"},{"subj":"473","pred":"source","obj":"LitCovid-PubTator"},{"subj":"474","pred":"source","obj":"LitCovid-PubTator"},{"subj":"475","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T58","span":{"begin":109,"end":115},"obj":"Body_part"},{"id":"T59","span":{"begin":160,"end":166},"obj":"Body_part"},{"id":"T60","span":{"begin":423,"end":429},"obj":"Body_part"}],"attributes":[{"id":"A58","pred":"fma_id","subj":"T58","obj":"http://purl.org/sig/ont/fma/fma7203"},{"id":"A59","pred":"fma_id","subj":"T59","obj":"http://purl.org/sig/ont/fma/fma7203"},{"id":"A60","pred":"fma_id","subj":"T60","obj":"http://purl.org/sig/ont/fma/fma7203"},{"subj":"T58","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T59","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T60","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T35","span":{"begin":109,"end":115},"obj":"Body_part"},{"id":"T36","span":{"begin":160,"end":166},"obj":"Body_part"},{"id":"T37","span":{"begin":423,"end":429},"obj":"Body_part"}],"attributes":[{"id":"A35","pred":"uberon_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"A36","pred":"uberon_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"A37","pred":"uberon_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"subj":"T35","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T36","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T37","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T71","span":{"begin":101,"end":123},"obj":"Disease"},{"id":"T72","span":{"begin":109,"end":123},"obj":"Disease"},{"id":"T74","span":{"begin":152,"end":174},"obj":"Disease"},{"id":"T75","span":{"begin":160,"end":174},"obj":"Disease"},{"id":"T77","span":{"begin":417,"end":436},"obj":"Disease"},{"id":"T78","span":{"begin":430,"end":436},"obj":"Disease"}],"attributes":[{"id":"A71","pred":"mondo_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/MONDO_0005300"},{"id":"A72","pred":"mondo_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/MONDO_0001343"},{"id":"A73","pred":"mondo_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/MONDO_0005240"},{"id":"A74","pred":"mondo_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/MONDO_0005300"},{"id":"A75","pred":"mondo_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/MONDO_0001343"},{"id":"A76","pred":"mondo_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/MONDO_0005240"},{"id":"A77","pred":"mondo_id","subj":"T77","obj":"http://purl.obolibrary.org/obo/MONDO_0002492"},{"id":"A78","pred":"mondo_id","subj":"T78","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"},{"subj":"T71","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T72","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T74","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T75","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T77","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T78","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T170","span":{"begin":109,"end":115},"obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"T171","span":{"begin":109,"end":115},"obj":"http://www.ebi.ac.uk/efo/EFO_0000927"},{"id":"T172","span":{"begin":109,"end":115},"obj":"http://www.ebi.ac.uk/efo/EFO_0000929"},{"id":"T173","span":{"begin":160,"end":166},"obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"T174","span":{"begin":160,"end":166},"obj":"http://www.ebi.ac.uk/efo/EFO_0000927"},{"id":"T175","span":{"begin":160,"end":166},"obj":"http://www.ebi.ac.uk/efo/EFO_0000929"},{"id":"T176","span":{"begin":260,"end":262},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T177","span":{"begin":423,"end":429},"obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"T178","span":{"begin":423,"end":429},"obj":"http://www.ebi.ac.uk/efo/EFO_0000927"},{"id":"T179","span":{"begin":423,"end":429},"obj":"http://www.ebi.ac.uk/efo/EFO_0000929"}],"attributes":[{"subj":"T170","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T171","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T172","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T173","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T174","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T175","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T176","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T177","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T178","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T179","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T141","span":{"begin":32,"end":42},"obj":"Chemical"},{"id":"T142","span":{"begin":560,"end":570},"obj":"Chemical"}],"attributes":[{"id":"A141","pred":"chebi_id","subj":"T141","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A142","pred":"chebi_id","subj":"T142","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"subj":"T141","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T142","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T28","span":{"begin":101,"end":123},"obj":"Phenotype"},{"id":"T29","span":{"begin":152,"end":174},"obj":"Phenotype"},{"id":"T30","span":{"begin":417,"end":436},"obj":"Phenotype"}],"attributes":[{"id":"A28","pred":"hp_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/HP_0012622"},{"id":"A29","pred":"hp_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/HP_0012622"},{"id":"A30","pred":"hp_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/HP_0001919"},{"subj":"T28","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T29","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T30","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T51","span":{"begin":0,"end":124},"obj":"Sentence"},{"id":"T52","span":{"begin":125,"end":665},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T51","pred":"source","obj":"LitCovid-sentences"},{"subj":"T52","pred":"source","obj":"LitCovid-sentences"}]},{"project":"2_test","denotations":[{"id":"32227760-32191259-75177464","span":{"begin":376,"end":378},"obj":"32191259"},{"id":"32227760-32171076-75177465","span":{"begin":452,"end":454},"obj":"32171076"},{"id":"32227760-32007143-75177466","span":{"begin":455,"end":457},"obj":"32007143"},{"id":"32227760-32167524-75177467","span":{"begin":458,"end":460},"obj":"32167524"}],"attributes":[{"subj":"32227760-32191259-75177464","pred":"source","obj":"2_test"},{"subj":"32227760-32171076-75177465","pred":"source","obj":"2_test"},{"subj":"32227760-32007143-75177466","pred":"source","obj":"2_test"},{"subj":"32227760-32167524-75177467","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#93c2ec","default":true},{"id":"LitCovid-PD-FMA-UBERON","color":"#dcec93"},{"id":"LitCovid-PD-UBERON","color":"#e293ec"},{"id":"LitCovid-PD-MONDO","color":"#93ecc8"},{"id":"LitCovid-PD-CLO","color":"#ecae93"},{"id":"LitCovid-PD-CHEBI","color":"#9493ec"},{"id":"LitCovid-PD-HP","color":"#abec93"},{"id":"LitCovid-sentences","color":"#ec93c5"},{"id":"2_test","color":"#93e0ec"}]}]}}