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PMC:7118659 / 9066-10037 JSONTXT

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LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 234-253 https://glytoucan.org/Structures/Glycans/G64581RP denotes N-acetylglucosamine
T2 313-325 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acids
T3 331-343 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acids
T4 546-557 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid
T5 713-724 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T11 122-134 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T12 122-126 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T13 234-253 Body_part denotes N-acetylglucosamine http://purl.org/sig/ont/fma/fma82787
T14 355-370 Body_part denotes monosaccharides http://purl.org/sig/ont/fma/fma82741
T15 384-393 Body_part denotes extremity http://purl.org/sig/ont/fma/fma7182
T16 397-402 Body_part denotes sugar http://purl.org/sig/ont/fma/fma82737
T17 421-448 Body_part denotes cell transmembrane proteins http://purl.org/sig/ont/fma/fma67858
T18 421-425 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T19 886-898 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T20 886-890 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T21 960-965 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T69 769-777 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T92 24-25 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T93 122-126 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T94 204-205 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T95 384-393 http://www.ebi.ac.uk/efo/EFO_0000876 denotes extremity
T96 421-425 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T97 637-644 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T98 657-662 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T99 844-845 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T100 878-879 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T101 880-885 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T102 886-890 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T103 955-959 http://purl.obolibrary.org/obo/CLO_0009524 denotes Vero
T104 955-959 http://purl.obolibrary.org/obo/CLO_0050515 denotes Vero
T105 960-965 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T86 0-11 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T87 145-156 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T88 178-185 Chemical denotes quinone http://purl.obolibrary.org/obo/CHEBI_36141
T89 230-253 Chemical denotes UDP-N-acetylglucosamine http://purl.obolibrary.org/obo/CHEBI_16264
T90 230-233 Chemical denotes UDP http://purl.obolibrary.org/obo/CHEBI_17659|http://purl.obolibrary.org/obo/CHEBI_58223
T92 234-253 Chemical denotes N-acetylglucosamine http://purl.obolibrary.org/obo/CHEBI_28009|http://purl.obolibrary.org/obo/CHEBI_59640
T94 313-325 Chemical denotes sialic acids http://purl.obolibrary.org/obo/CHEBI_26667
T95 320-325 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T96 331-343 Chemical denotes sialic acids http://purl.obolibrary.org/obo/CHEBI_26667
T97 338-343 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T98 355-370 Chemical denotes monosaccharides http://purl.obolibrary.org/obo/CHEBI_35381
T99 440-448 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T100 480-486 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T101 529-540 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T102 546-557 Chemical denotes sialic acid http://purl.obolibrary.org/obo/CHEBI_26667
T103 553-557 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T104 599-608 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T105 626-630 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T106 713-724 Chemical denotes sialic acid http://purl.obolibrary.org/obo/CHEBI_26667
T107 720-724 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T108 791-802 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T109 913-924 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T3 297-309 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T4 558-570 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T5 861-874 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
352 178-197 Gene denotes quinone reductase 2 Gene:4835
353 913-944 Gene denotes angiotensin-converting enzyme 2 Gene:59272
354 946-950 Gene denotes ACE2 Gene:59272
355 886-907 Gene denotes cell surface receptor Gene:57126
356 122-143 Gene denotes cell surface receptor Gene:57126
357 657-674 Species denotes human coronavirus Tax:694448
358 675-679 Species denotes HCoV Tax:694448
359 769-777 Species denotes SARS-CoV Tax:694009
360 0-11 Chemical denotes Chloroquine MESH:D002738
361 145-156 Chemical denotes Chloroquine MESH:D002738
362 313-325 Chemical denotes sialic acids MESH:D012794
363 331-343 Chemical denotes sialic acids MESH:D012794
364 355-370 Chemical denotes monosaccharides MESH:D009005
365 397-402 Chemical denotes sugar MESH:D000073893
366 529-540 Chemical denotes chloroquine MESH:D002738
367 546-557 Chemical denotes sialic acid MESH:D019158
368 713-724 Chemical denotes sialic acid MESH:D019158
369 791-802 Chemical denotes chloroquine MESH:D002738

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T52 0-144 Sentence denotes Chloroquine can inhibit a pre-entry step of the viral cycle by interfering with viral particles binding to their cellular cell surface receptor.
T53 145-326 Sentence denotes Chloroquine was shown to inhibit quinone reductase 2 [56], a structural neighbour of UDP-N-acetylglucosamine 2-epimerases [57] that are involved in the biosynthesis of sialic acids.
T54 327-499 Sentence denotes The sialic acids are acidic monosaccharides found at the extremity of sugar chains present on cell transmembrane proteins and are critical components of ligand recognition.
T55 500-752 Sentence denotes The possible interference of chloroquine with sialic acid biosynthesis could account for the broad antiviral spectrum of that drug since viruses such as the human coronavirus HCoV-O43 and the orthomyxoviruses use sialic acid moieties as receptors [58].
T56 753-971 Sentence denotes The potent anti-SARS-CoV-1 effects of chloroquine in vitro were considered attributable to a deficit in the glycosylation of a virus cell surface receptor, the angiotensin-converting enzyme 2 (ACE2) on Vero cells [59].

2_test

Id Subject Object Predicate Lexical cue
32171740-15078100-48148551 199-201 15078100 denotes 56
32171740-9068613-48148552 268-270 9068613 denotes 57
32171740-15766653-48148553 748-750 15766653 denotes 58
32171740-16115318-48148554 967-969 16115318 denotes 59
T40120 199-201 15078100 denotes 56
T97465 268-270 9068613 denotes 57
T26126 748-750 15766653 denotes 58
T92796 967-969 16115318 denotes 59