PMC:7118659 / 8264-8598 JSONTXT

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T62","span":{"begin":38,"end":45},"obj":"Disease"},{"id":"T63","span":{"begin":169,"end":180},"obj":"Disease"},{"id":"T64","span":{"begin":262,"end":276},"obj":"Disease"}],"attributes":[{"id":"A62","pred":"mondo_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/MONDO_0005136"},{"id":"A63","pred":"mondo_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/MONDO_0005283"},{"id":"A64","pred":"mondo_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/MONDO_0004994"}],"text":"Although the long use of this drug in malaria therapy demonstrates the safety of acute chloroquine administration to humans, one cannot ignore the minor risk of macular retinopathy, which depends on the cumulative dose [52], and the existence of some reports on cardiomyopathy as a severe adverse effect caused by chloroquine [53,54]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T84","span":{"begin":117,"end":123},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T85","span":{"begin":220,"end":222},"obj":"http://purl.obolibrary.org/obo/CLO_0001407"},{"id":"T86","span":{"begin":280,"end":281},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Although the long use of this drug in malaria therapy demonstrates the safety of acute chloroquine administration to humans, one cannot ignore the minor risk of macular retinopathy, which depends on the cumulative dose [52], and the existence of some reports on cardiomyopathy as a severe adverse effect caused by chloroquine [53,54]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T78","span":{"begin":30,"end":34},"obj":"Chemical"},{"id":"T79","span":{"begin":87,"end":98},"obj":"Chemical"},{"id":"T80","span":{"begin":314,"end":325},"obj":"Chemical"}],"attributes":[{"id":"A78","pred":"chebi_id","subj":"T78","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A79","pred":"chebi_id","subj":"T79","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A80","pred":"chebi_id","subj":"T80","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"}],"text":"Although the long use of this drug in malaria therapy demonstrates the safety of acute chloroquine administration to humans, one cannot ignore the minor risk of macular retinopathy, which depends on the cumulative dose [52], and the existence of some reports on cardiomyopathy as a severe adverse effect caused by chloroquine [53,54]."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T11","span":{"begin":169,"end":180},"obj":"Phenotype"},{"id":"T12","span":{"begin":262,"end":276},"obj":"Phenotype"}],"attributes":[{"id":"A11","pred":"hp_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/HP_0000488"},{"id":"A12","pred":"hp_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/HP_0001638"}],"text":"Although the long use of this drug in malaria therapy demonstrates the safety of acute chloroquine administration to humans, one cannot ignore the minor risk of macular retinopathy, which depends on the cumulative dose [52], and the existence of some reports on cardiomyopathy as a severe adverse effect caused by chloroquine [53,54]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"307","span":{"begin":117,"end":123},"obj":"Species"},{"id":"315","span":{"begin":87,"end":98},"obj":"Chemical"},{"id":"316","span":{"begin":314,"end":325},"obj":"Chemical"},{"id":"324","span":{"begin":38,"end":45},"obj":"Disease"},{"id":"325","span":{"begin":161,"end":180},"obj":"Disease"},{"id":"326","span":{"begin":262,"end":276},"obj":"Disease"}],"attributes":[{"id":"A307","pred":"tao:has_database_id","subj":"307","obj":"Tax:9606"},{"id":"A315","pred":"tao:has_database_id","subj":"315","obj":"MESH:D002738"},{"id":"A316","pred":"tao:has_database_id","subj":"316","obj":"MESH:D002738"},{"id":"A324","pred":"tao:has_database_id","subj":"324","obj":"MESH:D008288"},{"id":"A325","pred":"tao:has_database_id","subj":"325","obj":"MESH:C562746"},{"id":"A326","pred":"tao:has_database_id","subj":"326","obj":"MESH:D009202"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Although the long use of this drug in malaria therapy demonstrates the safety of acute chloroquine administration to humans, one cannot ignore the minor risk of macular retinopathy, which depends on the cumulative dose [52], and the existence of some reports on cardiomyopathy as a severe adverse effect caused by chloroquine [53,54]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T46","span":{"begin":0,"end":334},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Although the long use of this drug in malaria therapy demonstrates the safety of acute chloroquine administration to humans, one cannot ignore the minor risk of macular retinopathy, which depends on the cumulative dose [52], and the existence of some reports on cardiomyopathy as a severe adverse effect caused by chloroquine [53,54]."}

{"project":"2_test","denotations":[{"id":"32171740-1952638-48148548","span":{"begin":220,"end":222},"obj":"1952638"},{"id":"32171740-3796692-48148549","span":{"begin":327,"end":329},"obj":"3796692"},{"id":"32171740-8518071-48148550","span":{"begin":330,"end":332},"obj":"8518071"},{"id":"T26068","span":{"begin":220,"end":222},"obj":"1952638"},{"id":"T25498","span":{"begin":327,"end":329},"obj":"3796692"},{"id":"T96160","span":{"begin":330,"end":332},"obj":"8518071"}],"text":"Although the long use of this drug in malaria therapy demonstrates the safety of acute chloroquine administration to humans, one cannot ignore the minor risk of macular retinopathy, which depends on the cumulative dose [52], and the existence of some reports on cardiomyopathy as a severe adverse effect caused by chloroquine [53,54]."}