PMC:7118659 / 6712-7102 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T9","span":{"begin":158,"end":162},"obj":"Body_part"}],"attributes":[{"id":"A9","pred":"fma_id","subj":"T9","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Because of its broad spectrum of action against viruses, including most coronaviruses and particularly its close relative SARS-CoV-1, and because coronavirus cell entry occurs through the endolysosomal pathway [48], it made sense in a situation of a public-health emergency and the absence of any known efficient therapy to investigate the possible effect of chloroquine against SARS-CoV-2."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T53","span":{"begin":122,"end":130},"obj":"Disease"},{"id":"T54","span":{"begin":379,"end":387},"obj":"Disease"}],"attributes":[{"id":"A53","pred":"mondo_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A54","pred":"mondo_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Because of its broad spectrum of action against viruses, including most coronaviruses and particularly its close relative SARS-CoV-1, and because coronavirus cell entry occurs through the endolysosomal pathway [48], it made sense in a situation of a public-health emergency and the absence of any known efficient therapy to investigate the possible effect of chloroquine against SARS-CoV-2."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T70","span":{"begin":48,"end":55},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T71","span":{"begin":158,"end":162},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T72","span":{"begin":211,"end":213},"obj":"http://purl.obolibrary.org/obo/CLO_0001382"},{"id":"T73","span":{"begin":233,"end":234},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T74","span":{"begin":248,"end":249},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Because of its broad spectrum of action against viruses, including most coronaviruses and particularly its close relative SARS-CoV-1, and because coronavirus cell entry occurs through the endolysosomal pathway [48], it made sense in a situation of a public-health emergency and the absence of any known efficient therapy to investigate the possible effect of chloroquine against SARS-CoV-2."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T64","span":{"begin":359,"end":370},"obj":"Chemical"}],"attributes":[{"id":"A64","pred":"chebi_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"}],"text":"Because of its broad spectrum of action against viruses, including most coronaviruses and particularly its close relative SARS-CoV-1, and because coronavirus cell entry occurs through the endolysosomal pathway [48], it made sense in a situation of a public-health emergency and the absence of any known efficient therapy to investigate the possible effect of chloroquine against SARS-CoV-2."}

{"project":"LitCovid-PubTator","denotations":[{"id":"265","span":{"begin":72,"end":85},"obj":"Species"},{"id":"266","span":{"begin":122,"end":130},"obj":"Species"},{"id":"267","span":{"begin":146,"end":157},"obj":"Species"},{"id":"268","span":{"begin":379,"end":389},"obj":"Species"},{"id":"272","span":{"begin":359,"end":370},"obj":"Chemical"}],"attributes":[{"id":"A265","pred":"tao:has_database_id","subj":"265","obj":"Tax:11118"},{"id":"A266","pred":"tao:has_database_id","subj":"266","obj":"Tax:694009"},{"id":"A267","pred":"tao:has_database_id","subj":"267","obj":"Tax:11118"},{"id":"A268","pred":"tao:has_database_id","subj":"268","obj":"Tax:2697049"},{"id":"A272","pred":"tao:has_database_id","subj":"272","obj":"MESH:D002738"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Because of its broad spectrum of action against viruses, including most coronaviruses and particularly its close relative SARS-CoV-1, and because coronavirus cell entry occurs through the endolysosomal pathway [48], it made sense in a situation of a public-health emergency and the absence of any known efficient therapy to investigate the possible effect of chloroquine against SARS-CoV-2."}

{"project":"LitCovid-sentences","denotations":[{"id":"T40","span":{"begin":0,"end":390},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Because of its broad spectrum of action against viruses, including most coronaviruses and particularly its close relative SARS-CoV-1, and because coronavirus cell entry occurs through the endolysosomal pathway [48], it made sense in a situation of a public-health emergency and the absence of any known efficient therapy to investigate the possible effect of chloroquine against SARS-CoV-2."}