PMC:7118535 / 897-1851 JSONTXT

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    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"43","span":{"begin":67,"end":75},"obj":"Species"},{"id":"44","span":{"begin":456,"end":464},"obj":"Species"},{"id":"45","span":{"begin":552,"end":560},"obj":"Species"},{"id":"46","span":{"begin":621,"end":629},"obj":"Species"},{"id":"47","span":{"begin":882,"end":890},"obj":"Species"},{"id":"48","span":{"begin":21,"end":30},"obj":"Disease"},{"id":"49","span":{"begin":39,"end":47},"obj":"Disease"},{"id":"50","span":{"begin":149,"end":158},"obj":"Disease"},{"id":"51","span":{"begin":215,"end":232},"obj":"Disease"},{"id":"52","span":{"begin":234,"end":236},"obj":"Disease"},{"id":"53","span":{"begin":307,"end":342},"obj":"Disease"},{"id":"54","span":{"begin":357,"end":366},"obj":"Disease"},{"id":"55","span":{"begin":466,"end":468},"obj":"Disease"},{"id":"56","span":{"begin":543,"end":551},"obj":"Disease"},{"id":"57","span":{"begin":677,"end":679},"obj":"Disease"},{"id":"58","span":{"begin":872,"end":880},"obj":"Disease"},{"id":"59","span":{"begin":896,"end":898},"obj":"Disease"},{"id":"60","span":{"begin":910,"end":919},"obj":"Disease"},{"id":"61","span":{"begin":929,"end":931},"obj":"Disease"}],"attributes":[{"id":"A43","pred":"tao:has_database_id","subj":"43","obj":"Tax:9606"},{"id":"A44","pred":"tao:has_database_id","subj":"44","obj":"Tax:9606"},{"id":"A45","pred":"tao:has_database_id","subj":"45","obj":"Tax:9606"},{"id":"A46","pred":"tao:has_database_id","subj":"46","obj":"Tax:9606"},{"id":"A47","pred":"tao:has_database_id","subj":"47","obj":"Tax:9606"},{"id":"A48","pred":"tao:has_database_id","subj":"48","obj":"MESH:D003643"},{"id":"A49","pred":"tao:has_database_id","subj":"49","obj":"MESH:C000657245"},{"id":"A50","pred":"tao:has_database_id","subj":"50","obj":"MESH:D003643"},{"id":"A51","pred":"tao:has_database_id","subj":"51","obj":"MESH:D003920"},{"id":"A52","pred":"tao:has_database_id","subj":"52","obj":"MESH:D009223"},{"id":"A53","pred":"tao:has_database_id","subj":"53","obj":"MESH:D012128"},{"id":"A54","pred":"tao:has_database_id","subj":"54","obj":"MESH:D003643"},{"id":"A55","pred":"tao:has_database_id","subj":"55","obj":"MESH:D009223"},{"id":"A56","pred":"tao:has_database_id","subj":"56","obj":"MESH:C000657245"},{"id":"A57","pred":"tao:has_database_id","subj":"57","obj":"MESH:D009223"},{"id":"A58","pred":"tao:has_database_id","subj":"58","obj":"MESH:C000657245"},{"id":"A59","pred":"tao:has_database_id","subj":"59","obj":"MESH:D009223"},{"id":"A60","pred":"tao:has_database_id","subj":"60","obj":"MESH:D003643"},{"id":"A61","pred":"tao:has_database_id","subj":"61","obj":"MESH:D009223"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Although the overall mortality rate of COVID-19 is low (1.4–2.3%), patients with comorbidities are more likely to have severe disease and subsequent mortality [1], [2]. Most of the available studies have shown that diabetes mellitus (DM) as a distinctive comorbidity is associated with more severe disease, acute respiratory distress syndrome and increased mortality [1], [3], [4]. Amongst the 32 non-survivors from a group of 52 intensive care unit (ICU) patients, DM (22%) was a predominant underlying comorbidity [3]. Of the 1099 confirmed COVID-19 patients reported by Guan et al. from China, 173 had severe disease; patients with severe disease had a higher prevalence of DM (16.2%) as compared to those with non-severe disease (5.7%) [1]. Further, in the largest series reported by the Chinese Center for Disease Control and Prevention comprising of 72,314 cases of COVID-19, patients with DM had higher mortality (7.3% in DM vs. 2.3% overall) [2]."}

    LitCovid-PD-HP

    {"project":"LitCovid-PD-HP","denotations":[{"id":"T2","span":{"begin":215,"end":232},"obj":"Phenotype"},{"id":"T3","span":{"begin":234,"end":236},"obj":"Phenotype"},{"id":"T4","span":{"begin":313,"end":333},"obj":"Phenotype"},{"id":"T5","span":{"begin":466,"end":468},"obj":"Phenotype"},{"id":"T6","span":{"begin":677,"end":679},"obj":"Phenotype"},{"id":"T7","span":{"begin":896,"end":898},"obj":"Phenotype"},{"id":"T8","span":{"begin":929,"end":931},"obj":"Phenotype"}],"attributes":[{"id":"A2","pred":"hp_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/HP_0000819"},{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0000819"},{"id":"A4","pred":"hp_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/HP_0002098"},{"id":"A5","pred":"hp_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/HP_0000819"},{"id":"A6","pred":"hp_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/HP_0000819"},{"id":"A7","pred":"hp_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/HP_0000819"},{"id":"A8","pred":"hp_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/HP_0000819"}],"text":"Although the overall mortality rate of COVID-19 is low (1.4–2.3%), patients with comorbidities are more likely to have severe disease and subsequent mortality [1], [2]. Most of the available studies have shown that diabetes mellitus (DM) as a distinctive comorbidity is associated with more severe disease, acute respiratory distress syndrome and increased mortality [1], [3], [4]. Amongst the 32 non-survivors from a group of 52 intensive care unit (ICU) patients, DM (22%) was a predominant underlying comorbidity [3]. Of the 1099 confirmed COVID-19 patients reported by Guan et al. from China, 173 had severe disease; patients with severe disease had a higher prevalence of DM (16.2%) as compared to those with non-severe disease (5.7%) [1]. Further, in the largest series reported by the Chinese Center for Disease Control and Prevention comprising of 72,314 cases of COVID-19, patients with DM had higher mortality (7.3% in DM vs. 2.3% overall) [2]."}

    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T9","span":{"begin":39,"end":47},"obj":"Disease"},{"id":"T10","span":{"begin":215,"end":232},"obj":"Disease"},{"id":"T11","span":{"begin":234,"end":236},"obj":"Disease"},{"id":"T13","span":{"begin":307,"end":342},"obj":"Disease"},{"id":"T14","span":{"begin":313,"end":342},"obj":"Disease"},{"id":"T15","span":{"begin":466,"end":468},"obj":"Disease"},{"id":"T17","span":{"begin":543,"end":551},"obj":"Disease"},{"id":"T18","span":{"begin":677,"end":679},"obj":"Disease"},{"id":"T20","span":{"begin":872,"end":880},"obj":"Disease"},{"id":"T21","span":{"begin":896,"end":898},"obj":"Disease"},{"id":"T23","span":{"begin":929,"end":931},"obj":"Disease"}],"attributes":[{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0005015"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0005015"},{"id":"A12","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0016367"},{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A14","pred":"mondo_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/MONDO_0009971"},{"id":"A15","pred":"mondo_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/MONDO_0005015"},{"id":"A16","pred":"mondo_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/MONDO_0016367"},{"id":"A17","pred":"mondo_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A18","pred":"mondo_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/MONDO_0005015"},{"id":"A19","pred":"mondo_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/MONDO_0016367"},{"id":"A20","pred":"mondo_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A21","pred":"mondo_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/MONDO_0005015"},{"id":"A22","pred":"mondo_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/MONDO_0016367"},{"id":"A23","pred":"mondo_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/MONDO_0005015"},{"id":"A24","pred":"mondo_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/MONDO_0016367"}],"text":"Although the overall mortality rate of COVID-19 is low (1.4–2.3%), patients with comorbidities are more likely to have severe disease and subsequent mortality [1], [2]. Most of the available studies have shown that diabetes mellitus (DM) as a distinctive comorbidity is associated with more severe disease, acute respiratory distress syndrome and increased mortality [1], [3], [4]. Amongst the 32 non-survivors from a group of 52 intensive care unit (ICU) patients, DM (22%) was a predominant underlying comorbidity [3]. Of the 1099 confirmed COVID-19 patients reported by Guan et al. from China, 173 had severe disease; patients with severe disease had a higher prevalence of DM (16.2%) as compared to those with non-severe disease (5.7%) [1]. Further, in the largest series reported by the Chinese Center for Disease Control and Prevention comprising of 72,314 cases of COVID-19, patients with DM had higher mortality (7.3% in DM vs. 2.3% overall) [2]."}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T11","span":{"begin":241,"end":242},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T12","span":{"begin":373,"end":379},"obj":"http://purl.obolibrary.org/obo/CLO_0001302"},{"id":"T13","span":{"begin":416,"end":417},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T14","span":{"begin":427,"end":429},"obj":"http://purl.obolibrary.org/obo/CLO_0001407"},{"id":"T15","span":{"begin":470,"end":472},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"},{"id":"T16","span":{"begin":479,"end":480},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T17","span":{"begin":654,"end":655},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Although the overall mortality rate of COVID-19 is low (1.4–2.3%), patients with comorbidities are more likely to have severe disease and subsequent mortality [1], [2]. Most of the available studies have shown that diabetes mellitus (DM) as a distinctive comorbidity is associated with more severe disease, acute respiratory distress syndrome and increased mortality [1], [3], [4]. Amongst the 32 non-survivors from a group of 52 intensive care unit (ICU) patients, DM (22%) was a predominant underlying comorbidity [3]. Of the 1099 confirmed COVID-19 patients reported by Guan et al. from China, 173 had severe disease; patients with severe disease had a higher prevalence of DM (16.2%) as compared to those with non-severe disease (5.7%) [1]. Further, in the largest series reported by the Chinese Center for Disease Control and Prevention comprising of 72,314 cases of COVID-19, patients with DM had higher mortality (7.3% in DM vs. 2.3% overall) [2]."}

    LitCovid-PD-CHEBI

    {"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1","span":{"begin":234,"end":236},"obj":"Chemical"},{"id":"T2","span":{"begin":418,"end":423},"obj":"Chemical"},{"id":"T3","span":{"begin":466,"end":468},"obj":"Chemical"},{"id":"T4","span":{"begin":677,"end":679},"obj":"Chemical"},{"id":"T5","span":{"begin":896,"end":898},"obj":"Chemical"},{"id":"T6","span":{"begin":929,"end":931},"obj":"Chemical"}],"attributes":[{"id":"A1","pred":"chebi_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_141426"},{"id":"A2","pred":"chebi_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"},{"id":"A3","pred":"chebi_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_141426"},{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_141426"},{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_141426"},{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_141426"}],"text":"Although the overall mortality rate of COVID-19 is low (1.4–2.3%), patients with comorbidities are more likely to have severe disease and subsequent mortality [1], [2]. Most of the available studies have shown that diabetes mellitus (DM) as a distinctive comorbidity is associated with more severe disease, acute respiratory distress syndrome and increased mortality [1], [3], [4]. Amongst the 32 non-survivors from a group of 52 intensive care unit (ICU) patients, DM (22%) was a predominant underlying comorbidity [3]. Of the 1099 confirmed COVID-19 patients reported by Guan et al. from China, 173 had severe disease; patients with severe disease had a higher prevalence of DM (16.2%) as compared to those with non-severe disease (5.7%) [1]. Further, in the largest series reported by the Chinese Center for Disease Control and Prevention comprising of 72,314 cases of COVID-19, patients with DM had higher mortality (7.3% in DM vs. 2.3% overall) [2]."}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T8","span":{"begin":0,"end":168},"obj":"Sentence"},{"id":"T9","span":{"begin":169,"end":381},"obj":"Sentence"},{"id":"T10","span":{"begin":382,"end":520},"obj":"Sentence"},{"id":"T11","span":{"begin":521,"end":744},"obj":"Sentence"},{"id":"T12","span":{"begin":745,"end":954},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Although the overall mortality rate of COVID-19 is low (1.4–2.3%), patients with comorbidities are more likely to have severe disease and subsequent mortality [1], [2]. Most of the available studies have shown that diabetes mellitus (DM) as a distinctive comorbidity is associated with more severe disease, acute respiratory distress syndrome and increased mortality [1], [3], [4]. Amongst the 32 non-survivors from a group of 52 intensive care unit (ICU) patients, DM (22%) was a predominant underlying comorbidity [3]. Of the 1099 confirmed COVID-19 patients reported by Guan et al. from China, 173 had severe disease; patients with severe disease had a higher prevalence of DM (16.2%) as compared to those with non-severe disease (5.7%) [1]. Further, in the largest series reported by the Chinese Center for Disease Control and Prevention comprising of 72,314 cases of COVID-19, patients with DM had higher mortality (7.3% in DM vs. 2.3% overall) [2]."}