PMC:7116472 / 836-1842 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7116472","sourcedb":"PMC","sourceid":"7116472","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7116472","text":"cond cohort of patients recruited after model development between 21 May and 29 June 2020.\n\nParticipants\nAdults (age ≥18 years) admitted to hospital with covid-19 at least four weeks before final data extraction.\n\nMain Outcome Measure\nIn-hospital mortality.\n\nResults\n35 463 patients were included in the derivation dataset (mortality rate 32.2%) and 22 361 in the validation dataset (mortality rate 30.1%). The final 4C Mortality Score included eight variables readily available at initial hospital assessment: age, sex, number of comorbidities, respiratory rate, peripheral oxygen saturation, level of consciousness, urea level, and C reactive protein (score range 0-21 points). The 4C Score showed high discrimination for mortality (derivation cohort: area under the receiver operating characteristic curve 0.79, 95% confidence interval 0.78 to 0.79; validation cohort: 0.77, 0.76 to 0.77) with excellent calibration (validation: calibration-in-the-large=0, slope=1.0). Patients with a score of at least ","divisions":[{"label":"sec","span":{"begin":92,"end":212}},{"label":"title","span":{"begin":92,"end":104}},{"label":"p","span":{"begin":105,"end":212}},{"label":"sec","span":{"begin":214,"end":257}},{"label":"title","span":{"begin":214,"end":234}},{"label":"p","span":{"begin":235,"end":257}},{"label":"title","span":{"begin":259,"end":266}}],"tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"20","span":{"begin":15,"end":23},"obj":"Species"},{"id":"23","span":{"begin":154,"end":162},"obj":"Disease"},{"id":"25","span":{"begin":247,"end":256},"obj":"Disease"},{"id":"38","span":{"begin":634,"end":652},"obj":"Gene"},{"id":"39","span":{"begin":274,"end":282},"obj":"Species"},{"id":"40","span":{"begin":972,"end":980},"obj":"Species"},{"id":"41","span":{"begin":575,"end":581},"obj":"Chemical"},{"id":"42","span":{"begin":618,"end":622},"obj":"Chemical"},{"id":"43","span":{"begin":324,"end":333},"obj":"Disease"},{"id":"44","span":{"begin":384,"end":393},"obj":"Disease"},{"id":"45","span":{"begin":420,"end":429},"obj":"Disease"},{"id":"46","span":{"begin":724,"end":733},"obj":"Disease"}],"attributes":[{"id":"A20","pred":"tao:has_database_id","subj":"20","obj":"Tax:9606"},{"id":"A23","pred":"tao:has_database_id","subj":"23","obj":"MESH:C000657245"},{"id":"A25","pred":"tao:has_database_id","subj":"25","obj":"MESH:D003643"},{"id":"A38","pred":"tao:has_database_id","subj":"38","obj":"Gene:1401"},{"id":"A39","pred":"tao:has_database_id","subj":"39","obj":"Tax:9606"},{"id":"A40","pred":"tao:has_database_id","subj":"40","obj":"Tax:9606"},{"id":"A41","pred":"tao:has_database_id","subj":"41","obj":"MESH:D010100"},{"id":"A42","pred":"tao:has_database_id","subj":"42","obj":"MESH:D014508"},{"id":"A43","pred":"tao:has_database_id","subj":"43","obj":"MESH:D003643"},{"id":"A44","pred":"tao:has_database_id","subj":"44","obj":"MESH:D003643"},{"id":"A45","pred":"tao:has_database_id","subj":"45","obj":"MESH:D003643"},{"id":"A46","pred":"tao:has_database_id","subj":"46","obj":"MESH:D003643"},{"subj":"20","pred":"source","obj":"LitCovid-PubTator"},{"subj":"23","pred":"source","obj":"LitCovid-PubTator"},{"subj":"25","pred":"source","obj":"LitCovid-PubTator"},{"subj":"38","pred":"source","obj":"LitCovid-PubTator"},{"subj":"39","pred":"source","obj":"LitCovid-PubTator"},{"subj":"40","pred":"source","obj":"LitCovid-PubTator"},{"subj":"41","pred":"source","obj":"LitCovid-PubTator"},{"subj":"42","pred":"source","obj":"LitCovid-PubTator"},{"subj":"43","pred":"source","obj":"LitCovid-PubTator"},{"subj":"44","pred":"source","obj":"LitCovid-PubTator"},{"subj":"45","pred":"source","obj":"LitCovid-PubTator"},{"subj":"46","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T10","span":{"begin":92,"end":104},"obj":"Sentence"},{"id":"T11","span":{"begin":105,"end":212},"obj":"Sentence"},{"id":"T12","span":{"begin":214,"end":234},"obj":"Sentence"},{"id":"T13","span":{"begin":235,"end":257},"obj":"Sentence"},{"id":"T14","span":{"begin":259,"end":266},"obj":"Sentence"},{"id":"T15","span":{"begin":267,"end":406},"obj":"Sentence"},{"id":"T16","span":{"begin":407,"end":679},"obj":"Sentence"},{"id":"T17","span":{"begin":680,"end":871},"obj":"Sentence"},{"id":"T18","span":{"begin":872,"end":971},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T10","pred":"source","obj":"LitCovid-sentences"},{"subj":"T11","pred":"source","obj":"LitCovid-sentences"},{"subj":"T12","pred":"source","obj":"LitCovid-sentences"},{"subj":"T13","pred":"source","obj":"LitCovid-sentences"},{"subj":"T14","pred":"source","obj":"LitCovid-sentences"},{"subj":"T15","pred":"source","obj":"LitCovid-sentences"},{"subj":"T16","pred":"source","obj":"LitCovid-sentences"},{"subj":"T17","pred":"source","obj":"LitCovid-sentences"},{"subj":"T18","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#c993ec","default":true},{"id":"LitCovid-sentences","color":"#93ecaf"}]}]}}