PMC:7116472 / 8-1014 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7116472","sourcedb":"PMC","sourceid":"7116472","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7116472","text":"atification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score\n\nAbstract\nObjective\nTo develop and validate a pragmatic risk score to predict mortality in patients admitted to hospital with coronavirus disease 2019 (covid-19).\n\nDesign\nProspective observational cohort study.\n\nSetting\nInternational Severe Acute Respiratory and emerging Infections Consortium (ISARIC) World Health Organization (WHO) Clinical Characterisation Protocol UK (CCP-UK) study (performed by the ISARIC Coronavirus Clinical Characterisation Consortium—ISARIC-4C) in 260 hospitals across England, Scotland, and Wales. Model training was performed on a cohort of patients recruited between 6 February and 20 May 2020, with validation conducted on a second cohort of patients recruited after model development between 21 May and 29 June 2020.\n\nParticipants\nAdults (age ≥18 years) admitted to hospital with covid-19 at least four w","divisions":[{"label":"sec","span":{"begin":179,"end":331}},{"label":"title","span":{"begin":179,"end":188}},{"label":"p","span":{"begin":189,"end":331}},{"label":"sec","span":{"begin":333,"end":379}},{"label":"title","span":{"begin":333,"end":339}},{"label":"p","span":{"begin":340,"end":379}},{"label":"sec","span":{"begin":381,"end":918}},{"label":"title","span":{"begin":381,"end":388}},{"label":"p","span":{"begin":389,"end":918}},{"label":"title","span":{"begin":920,"end":932}}],"tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"3","span":{"begin":15,"end":23},"obj":"Species"},{"id":"4","span":{"begin":50,"end":58},"obj":"Disease"},{"id":"5","span":{"begin":153,"end":162},"obj":"Disease"},{"id":"10","span":{"begin":260,"end":268},"obj":"Species"},{"id":"11","span":{"begin":247,"end":256},"obj":"Disease"},{"id":"12","span":{"begin":295,"end":319},"obj":"Disease"},{"id":"13","span":{"begin":321,"end":329},"obj":"Disease"},{"id":"18","span":{"begin":582,"end":593},"obj":"Species"},{"id":"19","span":{"begin":740,"end":748},"obj":"Species"},{"id":"20","span":{"begin":843,"end":851},"obj":"Species"},{"id":"21","span":{"begin":441,"end":451},"obj":"Disease"},{"id":"23","span":{"begin":982,"end":990},"obj":"Disease"}],"attributes":[{"id":"A3","pred":"tao:has_database_id","subj":"3","obj":"Tax:9606"},{"id":"A4","pred":"tao:has_database_id","subj":"4","obj":"MESH:C000657245"},{"id":"A5","pred":"tao:has_database_id","subj":"5","obj":"MESH:D003643"},{"id":"A10","pred":"tao:has_database_id","subj":"10","obj":"Tax:9606"},{"id":"A11","pred":"tao:has_database_id","subj":"11","obj":"MESH:D003643"},{"id":"A12","pred":"tao:has_database_id","subj":"12","obj":"MESH:C000657245"},{"id":"A13","pred":"tao:has_database_id","subj":"13","obj":"MESH:C000657245"},{"id":"A18","pred":"tao:has_database_id","subj":"18","obj":"Tax:11118"},{"id":"A19","pred":"tao:has_database_id","subj":"19","obj":"Tax:9606"},{"id":"A20","pred":"tao:has_database_id","subj":"20","obj":"Tax:9606"},{"id":"A21","pred":"tao:has_database_id","subj":"21","obj":"MESH:D007239"},{"id":"A23","pred":"tao:has_database_id","subj":"23","obj":"MESH:C000657245"},{"subj":"3","pred":"source","obj":"LitCovid-PubTator"},{"subj":"4","pred":"source","obj":"LitCovid-PubTator"},{"subj":"5","pred":"source","obj":"LitCovid-PubTator"},{"subj":"10","pred":"source","obj":"LitCovid-PubTator"},{"subj":"11","pred":"source","obj":"LitCovid-PubTator"},{"subj":"12","pred":"source","obj":"LitCovid-PubTator"},{"subj":"13","pred":"source","obj":"LitCovid-PubTator"},{"subj":"18","pred":"source","obj":"LitCovid-PubTator"},{"subj":"19","pred":"source","obj":"LitCovid-PubTator"},{"subj":"20","pred":"source","obj":"LitCovid-PubTator"},{"subj":"21","pred":"source","obj":"LitCovid-PubTator"},{"subj":"23","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T2","span":{"begin":170,"end":178},"obj":"Sentence"},{"id":"T3","span":{"begin":179,"end":188},"obj":"Sentence"},{"id":"T4","span":{"begin":189,"end":331},"obj":"Sentence"},{"id":"T5","span":{"begin":333,"end":339},"obj":"Sentence"},{"id":"T6","span":{"begin":340,"end":379},"obj":"Sentence"},{"id":"T7","span":{"begin":381,"end":388},"obj":"Sentence"},{"id":"T8","span":{"begin":389,"end":695},"obj":"Sentence"},{"id":"T9","span":{"begin":696,"end":918},"obj":"Sentence"},{"id":"T10","span":{"begin":920,"end":932},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T2","pred":"source","obj":"LitCovid-sentences"},{"subj":"T3","pred":"source","obj":"LitCovid-sentences"},{"subj":"T4","pred":"source","obj":"LitCovid-sentences"},{"subj":"T5","pred":"source","obj":"LitCovid-sentences"},{"subj":"T6","pred":"source","obj":"LitCovid-sentences"},{"subj":"T7","pred":"source","obj":"LitCovid-sentences"},{"subj":"T8","pred":"source","obj":"LitCovid-sentences"},{"subj":"T9","pred":"source","obj":"LitCovid-sentences"},{"subj":"T10","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#93abec","default":true},{"id":"LitCovid-sentences","color":"#c5ec93"}]}]}}