PMC:7116472 / 21564-22517 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"316","span":{"begin":338,"end":346},"obj":"Species"},{"id":"317","span":{"begin":140,"end":149},"obj":"Disease"},{"id":"318","span":{"begin":246,"end":255},"obj":"Disease"},{"id":"319","span":{"begin":371,"end":380},"obj":"Disease"},{"id":"320","span":{"begin":438,"end":447},"obj":"Disease"},{"id":"321","span":{"begin":648,"end":656},"obj":"Disease"},{"id":"322","span":{"begin":736,"end":746},"obj":"Disease"},{"id":"323","span":{"begin":837,"end":846},"obj":"Disease"}],"attributes":[{"id":"A316","pred":"tao:has_database_id","subj":"316","obj":"Tax:9606"},{"id":"A317","pred":"tao:has_database_id","subj":"317","obj":"MESH:D003643"},{"id":"A318","pred":"tao:has_database_id","subj":"318","obj":"MESH:D003643"},{"id":"A319","pred":"tao:has_database_id","subj":"319","obj":"MESH:D011014"},{"id":"A320","pred":"tao:has_database_id","subj":"320","obj":"MESH:D003643"},{"id":"A321","pred":"tao:has_database_id","subj":"321","obj":"MESH:C000657245"},{"id":"A322","pred":"tao:has_database_id","subj":"322","obj":"MESH:C000657245"},{"id":"A323","pred":"tao:has_database_id","subj":"323","obj":"MESH:D003643"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"We performed a systematic literature search and identified 15 risk stratification scores that could beapplied to these data.62228-40 The 4C Mortality Score compared well against these existing risk stratification scores in predicting in-hospital mortality (table 6, fig 3, upper panel). Risk stratification scores originally validated in patients with community acquired pneumonia (n=9) generally had higher discrimination for inhospital mortality in the validation cohort (eg, A-DROP (area under the receiver operating characteristic curve 0.74, 95% confidence interval 0.73 to 0.74) and E-CURB65 (0.76, 0.74 to 0.79)) than those developed within covid-19 cohorts (n=4: Surgisphere (0.63, 0.62 to 0.64), DL score (0.67, 0.66 to 0.68), COVID-GRAM (0.71, 0.68 to 0.74), and Xie score (0.73, 0.70 to 0.75)). Performance metrics for the 4C Mortality Score compared well against existing risk stratification scores at specified cut-off values (appendix 13)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T145","span":{"begin":0,"end":286},"obj":"Sentence"},{"id":"T146","span":{"begin":287,"end":670},"obj":"Sentence"},{"id":"T147","span":{"begin":671,"end":805},"obj":"Sentence"},{"id":"T148","span":{"begin":806,"end":953},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"We performed a systematic literature search and identified 15 risk stratification scores that could beapplied to these data.62228-40 The 4C Mortality Score compared well against these existing risk stratification scores in predicting in-hospital mortality (table 6, fig 3, upper panel). Risk stratification scores originally validated in patients with community acquired pneumonia (n=9) generally had higher discrimination for inhospital mortality in the validation cohort (eg, A-DROP (area under the receiver operating characteristic curve 0.74, 95% confidence interval 0.73 to 0.74) and E-CURB65 (0.76, 0.74 to 0.79)) than those developed within covid-19 cohorts (n=4: Surgisphere (0.63, 0.62 to 0.64), DL score (0.67, 0.66 to 0.68), COVID-GRAM (0.71, 0.68 to 0.74), and Xie score (0.73, 0.70 to 0.75)). Performance metrics for the 4C Mortality Score compared well against existing risk stratification scores at specified cut-off values (appendix 13)."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T15","span":{"begin":371,"end":380},"obj":"Phenotype"}],"attributes":[{"id":"A15","pred":"hp_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"We performed a systematic literature search and identified 15 risk stratification scores that could beapplied to these data.62228-40 The 4C Mortality Score compared well against these existing risk stratification scores in predicting in-hospital mortality (table 6, fig 3, upper panel). Risk stratification scores originally validated in patients with community acquired pneumonia (n=9) generally had higher discrimination for inhospital mortality in the validation cohort (eg, A-DROP (area under the receiver operating characteristic curve 0.74, 95% confidence interval 0.73 to 0.74) and E-CURB65 (0.76, 0.74 to 0.79)) than those developed within covid-19 cohorts (n=4: Surgisphere (0.63, 0.62 to 0.64), DL score (0.67, 0.66 to 0.68), COVID-GRAM (0.71, 0.68 to 0.74), and Xie score (0.73, 0.70 to 0.75)). Performance metrics for the 4C Mortality Score compared well against existing risk stratification scores at specified cut-off values (appendix 13)."}