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PMC:7115396 / 6311-7671 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T33 1055-1063 Body_part denotes backbone http://purl.org/sig/ont/fma/fma13478
T34 1103-1107 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T83 387-392 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T84 612-614 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T85 634-639 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T86 684-686 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T87 773-775 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T88 781-786 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T89 918-925 http://purl.obolibrary.org/obo/CLO_0001409 denotes 5], [28
T90 971-972 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T91 1033-1035 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T92 1100-1102 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T93 1103-1107 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T94 1321-1329 http://purl.obolibrary.org/obo/NCBITaxon_9031 denotes chickens

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T5 393-402 http://purl.obolibrary.org/obo/GO_0016032 denotes virulence
T6 393-402 http://purl.obolibrary.org/obo/GO_0009405 denotes virulence
T7 556-569 http://purl.obolibrary.org/obo/GO_0044409 denotes host invasion

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T37 0-212 Sentence denotes In considering the limitations of the live attenuated and inactivated IBV vaccines, reverse genetic IBV vaccines have been developed in recent years as they display increased safety and efficacy [28], [29], [30].
T38 213-524 Sentence denotes As reverse genetic technology is primarily based on the H120 and Beaudette strains [31], [32], [33], both of which are passage-generated attenuated strains, the mechanism of virus virulence attenuation remains unclear, thereby posing difficulties in the development of attenuated vaccines using this technology.
T39 525-688 Sentence denotes In addition to the function of host invasion and increasing genetic diversity, the IBV S1 subunit can induce virus neutralizing and cross-reactive antibodies [34].
T40 689-933 Sentence denotes Therefore, some researchers have created an attenuated IBV vaccine by replacing the S1 or S genes from other virulent strains using reverse genetic technology to generate protection against strains of the corresponding serotype [5], [28], [30].
T41 934-1216 Sentence denotes In the present study, we constructed a recombinant strain, using the reverse genetic system. rH120-S1/YZ is based on the backbone of the vaccine strain H120, and the S1 gene was replaced with that of the QX-like nephropathogenic strain, ck/CH/IBYZ/2011, which was isolated in China.
T42 1217-1360 Sentence denotes Our results demonstrate that this recombinant strain is safe and provides effective protection in young chickens against QX-like IBV challenge.

2_test

Id Subject Object Predicate Lexical cue
32057575-29366709-143294052 202-204 29366709 denotes 29
32057575-30355423-143294053 208-210 30355423 denotes 30
32057575-11711626-143294054 297-299 11711626 denotes 31
32057575-22999521-143294055 303-305 22999521 denotes 32
32057575-23840781-143294056 309-311 23840781 denotes 33
32057575-7980002-143294057 684-686 7980002 denotes 34
32057575-12885925-143294058 918-919 12885925 denotes 5
32057575-30355423-143294059 929-931 30355423 denotes 30

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
99 1321-1329 Species denotes chickens Tax:9031
100 70-73 Species denotes IBV Tax:11120
101 100-103 Species denotes IBV Tax:11120
102 608-611 Species denotes IBV Tax:11120
103 744-747 Species denotes IBV Tax:11120
104 1346-1349 Species denotes IBV Tax:11120
105 1146-1162 Disease denotes nephropathogenic