PMC:7115396 / 26420-27709 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T147","span":{"begin":382,"end":385},"obj":"Body_part"},{"id":"T148","span":{"begin":711,"end":714},"obj":"Body_part"}],"attributes":[{"id":"A147","pred":"fma_id","subj":"T147","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A148","pred":"fma_id","subj":"T148","obj":"http://purl.org/sig/ont/fma/fma67095"}],"text":"3.2.4 Viral load in the oral and cloacal swabs\nIn all IBV infection groups, the viral load in both the oral and cloacal swabs generally showed a gradual decline from 7 dpi to 26 dpi. Compared with the rH120 group, The reduction in viral load between 14 or 18 dpi was significantly greater for chickens infected with rH120-S1/YZ than for chickens infected with rH120, and the viral RNA of the QX-like strain rIBYZ was lower than that of the rH120 group at 7, 14, and 18 dpi but with no statistically significance (Fig. 6 A). In contrast, the viral load in the cloacal swab of the rIBYZ group was significantly higher than that of the rH120 and rH120-S1/YZ groups at 7 dpi. Compared with other groups, the viral RNA in the cloacal swab of the rH120-S1/YZ group was significantly lower at 7, 14, and 22 dpi (Fig. 6B). No virus was detected in the control group at any time point.\nFig. 6 Viral loads at 7, 14, 18, 22, and 26 dpi in the oral and cloacal swabs of chickens infected with the recombinant rH120, rIBYZ, and rH120-S1/YZ strains. All data are presented as the mean ± standard error of the mean (SEM); ***Indicates an extremely significant difference at P ≤ 0.001; **Indicates a highly significant difference at 0.001 \u003c P ≤ 0.01; *Indicates significant difference at 0.01 \u003c P ≤ 0.05."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T34","span":{"begin":59,"end":68},"obj":"Disease"}],"attributes":[{"id":"A34","pred":"mondo_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"3.2.4 Viral load in the oral and cloacal swabs\nIn all IBV infection groups, the viral load in both the oral and cloacal swabs generally showed a gradual decline from 7 dpi to 26 dpi. Compared with the rH120 group, The reduction in viral load between 14 or 18 dpi was significantly greater for chickens infected with rH120-S1/YZ than for chickens infected with rH120, and the viral RNA of the QX-like strain rIBYZ was lower than that of the rH120 group at 7, 14, and 18 dpi but with no statistically significance (Fig. 6 A). In contrast, the viral load in the cloacal swab of the rIBYZ group was significantly higher than that of the rH120 and rH120-S1/YZ groups at 7 dpi. Compared with other groups, the viral RNA in the cloacal swab of the rH120-S1/YZ group was significantly lower at 7, 14, and 22 dpi (Fig. 6B). No virus was detected in the control group at any time point.\nFig. 6 Viral loads at 7, 14, 18, 22, and 26 dpi in the oral and cloacal swabs of chickens infected with the recombinant rH120, rIBYZ, and rH120-S1/YZ strains. All data are presented as the mean ± standard error of the mean (SEM); ***Indicates an extremely significant difference at P ≤ 0.001; **Indicates a highly significant difference at 0.001 \u003c P ≤ 0.01; *Indicates significant difference at 0.01 \u003c P ≤ 0.05."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T393","span":{"begin":144,"end":145},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T394","span":{"begin":257,"end":259},"obj":"http://purl.obolibrary.org/obo/CLO_0050510"},{"id":"T395","span":{"begin":294,"end":302},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9031"},{"id":"T396","span":{"begin":323,"end":325},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T397","span":{"begin":338,"end":346},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9031"},{"id":"T398","span":{"begin":467,"end":469},"obj":"http://purl.obolibrary.org/obo/CLO_0050510"},{"id":"T399","span":{"begin":521,"end":522},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T400","span":{"begin":650,"end":652},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T401","span":{"begin":748,"end":750},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T402","span":{"begin":798,"end":800},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"},{"id":"T403","span":{"begin":819,"end":824},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T404","span":{"begin":907,"end":909},"obj":"http://purl.obolibrary.org/obo/CLO_0050510"},{"id":"T405","span":{"begin":911,"end":913},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"},{"id":"T406","span":{"begin":959,"end":967},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9031"},{"id":"T407","span":{"begin":1022,"end":1024},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T408","span":{"begin":1124,"end":1133},"obj":"http://www.ebi.ac.uk/efo/EFO_0000876"},{"id":"T409","span":{"begin":1183,"end":1184},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"3.2.4 Viral load in the oral and cloacal swabs\nIn all IBV infection groups, the viral load in both the oral and cloacal swabs generally showed a gradual decline from 7 dpi to 26 dpi. Compared with the rH120 group, The reduction in viral load between 14 or 18 dpi was significantly greater for chickens infected with rH120-S1/YZ than for chickens infected with rH120, and the viral RNA of the QX-like strain rIBYZ was lower than that of the rH120 group at 7, 14, and 18 dpi but with no statistically significance (Fig. 6 A). In contrast, the viral load in the cloacal swab of the rIBYZ group was significantly higher than that of the rH120 and rH120-S1/YZ groups at 7 dpi. Compared with other groups, the viral RNA in the cloacal swab of the rH120-S1/YZ group was significantly lower at 7, 14, and 22 dpi (Fig. 6B). No virus was detected in the control group at any time point.\nFig. 6 Viral loads at 7, 14, 18, 22, and 26 dpi in the oral and cloacal swabs of chickens infected with the recombinant rH120, rIBYZ, and rH120-S1/YZ strains. All data are presented as the mean ± standard error of the mean (SEM); ***Indicates an extremely significant difference at P ≤ 0.001; **Indicates a highly significant difference at 0.001 \u003c P ≤ 0.01; *Indicates significant difference at 0.01 \u003c P ≤ 0.05."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T82","span":{"begin":208,"end":213},"obj":"Chemical"},{"id":"T83","span":{"begin":447,"end":452},"obj":"Chemical"},{"id":"T84","span":{"begin":586,"end":591},"obj":"Chemical"},{"id":"T85","span":{"begin":754,"end":759},"obj":"Chemical"},{"id":"T86","span":{"begin":853,"end":858},"obj":"Chemical"}],"attributes":[{"id":"A82","pred":"chebi_id","subj":"T82","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"},{"id":"A83","pred":"chebi_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"},{"id":"A84","pred":"chebi_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"},{"id":"A85","pred":"chebi_id","subj":"T85","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"},{"id":"A86","pred":"chebi_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"}],"text":"3.2.4 Viral load in the oral and cloacal swabs\nIn all IBV infection groups, the viral load in both the oral and cloacal swabs generally showed a gradual decline from 7 dpi to 26 dpi. Compared with the rH120 group, The reduction in viral load between 14 or 18 dpi was significantly greater for chickens infected with rH120-S1/YZ than for chickens infected with rH120, and the viral RNA of the QX-like strain rIBYZ was lower than that of the rH120 group at 7, 14, and 18 dpi but with no statistically significance (Fig. 6 A). In contrast, the viral load in the cloacal swab of the rIBYZ group was significantly higher than that of the rH120 and rH120-S1/YZ groups at 7 dpi. Compared with other groups, the viral RNA in the cloacal swab of the rH120-S1/YZ group was significantly lower at 7, 14, and 22 dpi (Fig. 6B). No virus was detected in the control group at any time point.\nFig. 6 Viral loads at 7, 14, 18, 22, and 26 dpi in the oral and cloacal swabs of chickens infected with the recombinant rH120, rIBYZ, and rH120-S1/YZ strains. All data are presented as the mean ± standard error of the mean (SEM); ***Indicates an extremely significant difference at P ≤ 0.001; **Indicates a highly significant difference at 0.001 \u003c P ≤ 0.01; *Indicates significant difference at 0.01 \u003c P ≤ 0.05."}

{"project":"LitCovid-sentences","denotations":[{"id":"T185","span":{"begin":0,"end":47},"obj":"Sentence"},{"id":"T186","span":{"begin":48,"end":183},"obj":"Sentence"},{"id":"T187","span":{"begin":184,"end":524},"obj":"Sentence"},{"id":"T188","span":{"begin":525,"end":672},"obj":"Sentence"},{"id":"T189","span":{"begin":673,"end":815},"obj":"Sentence"},{"id":"T190","span":{"begin":816,"end":877},"obj":"Sentence"},{"id":"T191","span":{"begin":878,"end":1036},"obj":"Sentence"},{"id":"T192","span":{"begin":1037,"end":1289},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"3.2.4 Viral load in the oral and cloacal swabs\nIn all IBV infection groups, the viral load in both the oral and cloacal swabs generally showed a gradual decline from 7 dpi to 26 dpi. Compared with the rH120 group, The reduction in viral load between 14 or 18 dpi was significantly greater for chickens infected with rH120-S1/YZ than for chickens infected with rH120, and the viral RNA of the QX-like strain rIBYZ was lower than that of the rH120 group at 7, 14, and 18 dpi but with no statistically significance (Fig. 6 A). In contrast, the viral load in the cloacal swab of the rIBYZ group was significantly higher than that of the rH120 and rH120-S1/YZ groups at 7 dpi. Compared with other groups, the viral RNA in the cloacal swab of the rH120-S1/YZ group was significantly lower at 7, 14, and 22 dpi (Fig. 6B). No virus was detected in the control group at any time point.\nFig. 6 Viral loads at 7, 14, 18, 22, and 26 dpi in the oral and cloacal swabs of chickens infected with the recombinant rH120, rIBYZ, and rH120-S1/YZ strains. All data are presented as the mean ± standard error of the mean (SEM); ***Indicates an extremely significant difference at P ≤ 0.001; **Indicates a highly significant difference at 0.001 \u003c P ≤ 0.01; *Indicates significant difference at 0.01 \u003c P ≤ 0.05."}

{"project":"LitCovid-PubTator","denotations":[{"id":"394","span":{"begin":959,"end":967},"obj":"Species"},{"id":"395","span":{"begin":968,"end":976},"obj":"Disease"},{"id":"403","span":{"begin":294,"end":302},"obj":"Species"},{"id":"404","span":{"begin":338,"end":346},"obj":"Species"},{"id":"405","span":{"begin":55,"end":58},"obj":"Species"},{"id":"406","span":{"begin":580,"end":585},"obj":"Chemical"},{"id":"407","span":{"begin":59,"end":68},"obj":"Disease"},{"id":"408","span":{"begin":303,"end":311},"obj":"Disease"},{"id":"409","span":{"begin":347,"end":355},"obj":"Disease"}],"attributes":[{"id":"A394","pred":"tao:has_database_id","subj":"394","obj":"Tax:9031"},{"id":"A395","pred":"tao:has_database_id","subj":"395","obj":"MESH:D007239"},{"id":"A403","pred":"tao:has_database_id","subj":"403","obj":"Tax:9031"},{"id":"A404","pred":"tao:has_database_id","subj":"404","obj":"Tax:9031"},{"id":"A405","pred":"tao:has_database_id","subj":"405","obj":"Tax:11120"},{"id":"A407","pred":"tao:has_database_id","subj":"407","obj":"MESH:D007239"},{"id":"A408","pred":"tao:has_database_id","subj":"408","obj":"MESH:D007239"},{"id":"A409","pred":"tao:has_database_id","subj":"409","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"3.2.4 Viral load in the oral and cloacal swabs\nIn all IBV infection groups, the viral load in both the oral and cloacal swabs generally showed a gradual decline from 7 dpi to 26 dpi. Compared with the rH120 group, The reduction in viral load between 14 or 18 dpi was significantly greater for chickens infected with rH120-S1/YZ than for chickens infected with rH120, and the viral RNA of the QX-like strain rIBYZ was lower than that of the rH120 group at 7, 14, and 18 dpi but with no statistically significance (Fig. 6 A). In contrast, the viral load in the cloacal swab of the rIBYZ group was significantly higher than that of the rH120 and rH120-S1/YZ groups at 7 dpi. Compared with other groups, the viral RNA in the cloacal swab of the rH120-S1/YZ group was significantly lower at 7, 14, and 22 dpi (Fig. 6B). No virus was detected in the control group at any time point.\nFig. 6 Viral loads at 7, 14, 18, 22, and 26 dpi in the oral and cloacal swabs of chickens infected with the recombinant rH120, rIBYZ, and rH120-S1/YZ strains. All data are presented as the mean ± standard error of the mean (SEM); ***Indicates an extremely significant difference at P ≤ 0.001; **Indicates a highly significant difference at 0.001 \u003c P ≤ 0.01; *Indicates significant difference at 0.01 \u003c P ≤ 0.05."}