PMC:7115396 / 181-597 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T3","span":{"begin":135,"end":143},"obj":"Body_part"},{"id":"T4","span":{"begin":184,"end":188},"obj":"Body_part"}],"attributes":[{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma13478"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma74402"}],"text":"• The reverse genetic operating systems of IBV H120 and IBYZ strains were created.\n• We constructed rH120-S1/YZ strain, based on the backbone of the H120 vaccine strain, with the S1 gene replaced with that of the QX-like nephropathogenic strain, ck/CH/IBYZ/2011.\n• We demonstrated that rH120-S1/YZ had the potential to be a candidate vaccine strain for the prevention and control of the epidemic of renal strains."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T3","span":{"begin":108,"end":110},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T4","span":{"begin":181,"end":183},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T5","span":{"begin":184,"end":188},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T6","span":{"begin":295,"end":297},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T7","span":{"begin":325,"end":326},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"• The reverse genetic operating systems of IBV H120 and IBYZ strains were created.\n• We constructed rH120-S1/YZ strain, based on the backbone of the H120 vaccine strain, with the S1 gene replaced with that of the QX-like nephropathogenic strain, ck/CH/IBYZ/2011.\n• We demonstrated that rH120-S1/YZ had the potential to be a candidate vaccine strain for the prevention and control of the epidemic of renal strains."}

{"project":"LitCovid-sentences","denotations":[{"id":"T3","span":{"begin":0,"end":83},"obj":"Sentence"},{"id":"T4","span":{"begin":84,"end":264},"obj":"Sentence"},{"id":"T5","span":{"begin":265,"end":416},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"• The reverse genetic operating systems of IBV H120 and IBYZ strains were created.\n• We constructed rH120-S1/YZ strain, based on the backbone of the H120 vaccine strain, with the S1 gene replaced with that of the QX-like nephropathogenic strain, ck/CH/IBYZ/2011.\n• We demonstrated that rH120-S1/YZ had the potential to be a candidate vaccine strain for the prevention and control of the epidemic of renal strains."}

{"project":"LitCovid-PubTator","denotations":[{"id":"7","span":{"begin":44,"end":47},"obj":"Species"},{"id":"10","span":{"begin":102,"end":107},"obj":"Chemical"},{"id":"11","span":{"begin":223,"end":239},"obj":"Disease"}],"attributes":[{"id":"A7","pred":"tao:has_database_id","subj":"7","obj":"Tax:11120"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"• The reverse genetic operating systems of IBV H120 and IBYZ strains were created.\n• We constructed rH120-S1/YZ strain, based on the backbone of the H120 vaccine strain, with the S1 gene replaced with that of the QX-like nephropathogenic strain, ck/CH/IBYZ/2011.\n• We demonstrated that rH120-S1/YZ had the potential to be a candidate vaccine strain for the prevention and control of the epidemic of renal strains."}