PMC:7114094 / 8224-8545 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"235","span":{"begin":224,"end":229},"obj":"Gene"},{"id":"241","span":{"begin":33,"end":36},"obj":"Chemical"},{"id":"242","span":{"begin":114,"end":117},"obj":"Chemical"}],"attributes":[{"id":"A235","pred":"tao:has_database_id","subj":"235","obj":"Gene:5045"},{"id":"A241","pred":"tao:has_database_id","subj":"241","obj":"MESH:D001120"},{"id":"A242","pred":"tao:has_database_id","subj":"242","obj":"MESH:D007930"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"This motif exhibits the critical Arg at P1 and basic residues at P2 and P4, as well as P6 and P8 and an aliphatic Leu at P2’ positions (Table 1) (Schechter and Berger nomenclature (Schechter and Berger, 1968)), typical of a furin-like cleavage specificity (Braun and Sauter, 2019; Izaguirre, 2019; Seidah and Prat, 2012)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T122","span":{"begin":40,"end":42},"obj":"http://purl.obolibrary.org/obo/CLO_0008285"},{"id":"T123","span":{"begin":65,"end":67},"obj":"http://purl.obolibrary.org/obo/CLO_0008307"},{"id":"T124","span":{"begin":72,"end":74},"obj":"http://purl.obolibrary.org/obo/CLO_0008337"},{"id":"T125","span":{"begin":87,"end":89},"obj":"http://purl.obolibrary.org/obo/CLO_0008339"},{"id":"T126","span":{"begin":121,"end":123},"obj":"http://purl.obolibrary.org/obo/CLO_0008307"},{"id":"T127","span":{"begin":222,"end":223},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"This motif exhibits the critical Arg at P1 and basic residues at P2 and P4, as well as P6 and P8 and an aliphatic Leu at P2’ positions (Table 1) (Schechter and Berger nomenclature (Schechter and Berger, 1968)), typical of a furin-like cleavage specificity (Braun and Sauter, 2019; Izaguirre, 2019; Seidah and Prat, 2012)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T62","span":{"begin":33,"end":36},"obj":"Chemical"},{"id":"T64","span":{"begin":40,"end":42},"obj":"Chemical"},{"id":"T65","span":{"begin":65,"end":67},"obj":"Chemical"},{"id":"T66","span":{"begin":72,"end":74},"obj":"Chemical"},{"id":"T67","span":{"begin":114,"end":117},"obj":"Chemical"},{"id":"T70","span":{"begin":121,"end":123},"obj":"Chemical"}],"attributes":[{"id":"A62","pred":"chebi_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/CHEBI_16467"},{"id":"A63","pred":"chebi_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/CHEBI_29952"},{"id":"A64","pred":"chebi_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/CHEBI_60949"},{"id":"A65","pred":"chebi_id","subj":"T65","obj":"http://purl.obolibrary.org/obo/CHEBI_33472"},{"id":"A66","pred":"chebi_id","subj":"T66","obj":"http://purl.obolibrary.org/obo/CHEBI_35895"},{"id":"A67","pred":"chebi_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/CHEBI_15603"},{"id":"A68","pred":"chebi_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/CHEBI_25017"},{"id":"A69","pred":"chebi_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/CHEBI_30006"},{"id":"A70","pred":"chebi_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/CHEBI_33472"}],"text":"This motif exhibits the critical Arg at P1 and basic residues at P2 and P4, as well as P6 and P8 and an aliphatic Leu at P2’ positions (Table 1) (Schechter and Berger nomenclature (Schechter and Berger, 1968)), typical of a furin-like cleavage specificity (Braun and Sauter, 2019; Izaguirre, 2019; Seidah and Prat, 2012)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T52","span":{"begin":0,"end":321},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"This motif exhibits the critical Arg at P1 and basic residues at P2 and P4, as well as P6 and P8 and an aliphatic Leu at P2’ positions (Table 1) (Schechter and Berger nomenclature (Schechter and Berger, 1968)), typical of a furin-like cleavage specificity (Braun and Sauter, 2019; Izaguirre, 2019; Seidah and Prat, 2012)."}