PMC:7113610 / 7099-9898
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 261 | 2393-2397 | Gene | denotes | ACE2 | Gene:59272 |
| 262 | 2407-2411 | Gene | denotes | ACE2 | Gene:59272 |
| 263 | 2065-2073 | Species | denotes | SARS-CoV | Tax:694009 |
| 264 | 2074-2084 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 265 | 2301-2305 | Species | denotes | dogs | Tax:9615 |
| 266 | 2386-2392 | Species | denotes | humans | Tax:9606 |
| 267 | 2664-2672 | Species | denotes | patients | Tax:9606 |
| 268 | 2706-2714 | Species | denotes | patients | Tax:9606 |
| 269 | 2737-2745 | Species | denotes | patients | Tax:9606 |
| 270 | 2347-2355 | Disease | denotes | infected | MESH:D007239 |
| 271 | 2456-2461 | Disease | denotes | fever | MESH:D005334 |
| 272 | 2463-2470 | Disease | denotes | malaise | MESH:D005221 |
| 273 | 2472-2479 | Disease | denotes | myalgia | MESH:D063806 |
| 274 | 2481-2489 | Disease | denotes | headache | MESH:D006261 |
| 275 | 2491-2500 | Disease | denotes | diarrhoea | MESH:D003967 |
| 276 | 2513-2518 | Disease | denotes | cough | MESH:D003371 |
| 277 | 2523-2548 | Disease | denotes | shortness of breath Cough | MESH:D003371 |
| 278 | 2550-2555 | Disease | denotes | fever | MESH:D005334 |
| 279 | 2560-2604 | Disease | denotes | shortness of breath [12], [23], [85] Disease | MESH:D004417 |
| 280 | 2618-2622 | Disease | denotes | ARDS | MESH:D012128 |
| 281 | 2629-2637 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 282 | 2655-2663 | Disease | denotes | infected | MESH:D007239 |
| 283 | 2732-2736 | Disease | denotes | died | MESH:D003643 |
| 286 | 2031-2039 | Species | denotes | SARS-CoV | Tax:694009 |
| 287 | 2044-2054 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 310 | 203-211 | Species | denotes | SARS-CoV | Tax:694009 |
| 311 | 250-262 | Species | denotes | raccoon dogs | Tax:34880 |
| 312 | 544-551 | Species | denotes | persons | Tax:9606 |
| 313 | 643-659 | Species | denotes | SARS-coronavirus | Tax:694009 |
| 314 | 694-710 | Species | denotes | SARS-coronavirus | Tax:694009 |
| 315 | 733-739 | Species | denotes | humans | Tax:9606 |
| 316 | 921-972 | Species | denotes | Middle East respiratory syndrome (MERS) coronavirus | Tax:1335626 |
| 317 | 1016-1032 | Species | denotes | MERS-coronavirus | Tax:1335626 |
| 318 | 1050-1066 | Species | denotes | beta-coronavirus | Tax:694002 |
| 319 | 1078-1084 | Species | denotes | camels | Tax:9837 |
| 320 | 1147-1163 | Species | denotes | MERS-coronavirus | Tax:1335626 |
| 321 | 1430-1447 | Species | denotes | novel coronavirus | Tax:2697049 |
| 322 | 1678-1695 | Species | denotes | novel coronavirus | Tax:2697049 |
| 323 | 1716-1724 | Species | denotes | SARS-CoV | Tax:694009 |
| 324 | 1765-1773 | Species | denotes | Beta-CoV | Tax:694002 |
| 325 | 1968-1974 | Species | denotes | humans | Tax:9606 |
| 326 | 1185-1197 | Species | denotes | Pipistrellus | Tax:694008 |
| 327 | 838-846 | Species | denotes | SARS-CoV | Tax:694009 |
| 328 | 177-186 | Disease | denotes | infection | MESH:D007239 |
| 329 | 301-310 | Disease | denotes | infection | MESH:D007239 |
| 330 | 1090-1098 | Disease | denotes | zoonotic | MESH:D015047 |
| 331 | 1907-1915 | Disease | denotes | zoonotic | MESH:D015047 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T10 | 267-271 | Body_part | denotes | palm | http://purl.org/sig/ont/fma/fma24920 |
| T11 | 416-419 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T12 | 457-461 | Body_part | denotes | palm | http://purl.org/sig/ont/fma/fma24920 |
| T13 | 1662-1674 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T14 | 2278-2282 | Body_part | denotes | palm | http://purl.org/sig/ont/fma/fma24920 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T74 | 177-186 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T75 | 203-211 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T76 | 203-207 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T77 | 301-310 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T78 | 643-659 | Disease | denotes | SARS-coronavirus | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T79 | 643-647 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T80 | 694-710 | Disease | denotes | SARS-coronavirus | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T81 | 694-698 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T82 | 838-846 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T83 | 838-842 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T84 | 1453-1457 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T85 | 1716-1724 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T86 | 1716-1720 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T87 | 2031-2039 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T88 | 2031-2035 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T89 | 2044-2052 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T90 | 2044-2048 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T91 | 2065-2073 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T92 | 2065-2069 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T93 | 2074-2082 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T94 | 2074-2078 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T95 | 2491-2500 | Disease | denotes | diarrhoea | http://purl.obolibrary.org/obo/MONDO_0001673 |
| T96 | 2612-2616 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T97 | 2618-2622 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T98 | 2623-2627 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T99 | 2629-2637 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T74 | 239-246 | http://purl.obolibrary.org/obo/CLO_0009985 | denotes | focused |
| T75 | 250-257 | http://purl.obolibrary.org/obo/NCBITaxon_9654 | denotes | raccoon |
| T76 | 282-283 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T77 | 733-739 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T78 | 804-808 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bats |
| T79 | 873-877 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bats |
| T80 | 881-882 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T81 | 1078-1084 | http://purl.obolibrary.org/obo/NCBITaxon_9837 | denotes | camels |
| T82 | 1088-1089 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T83 | 1123-1125 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T84 | 1131-1132 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T85 | 1213-1217 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bats |
| T86 | 1240-1244 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bats |
| T87 | 1293-1298 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T88 | 1322-1323 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T89 | 1463-1466 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bat |
| T90 | 1467-1474 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T91 | 1524-1528 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bats |
| T92 | 1569-1571 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T93 | 1714-1715 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T94 | 1751-1752 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T95 | 1810-1815 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T96 | 1959-1964 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T97 | 1968-1974 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T98 | 2311-2313 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T99 | 2386-2392 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T100 | 2422-2424 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T15 | 1050-1054 | Chemical | denotes | beta | http://purl.obolibrary.org/obo/CHEBI_10545 |
| T16 | 1324-1329 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T17 | 1662-1674 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3 | 893-910 | http://purl.obolibrary.org/obo/GO_0019079 | denotes | viral replication |
| T4 | 893-910 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral replication |
| T5 | 1600-1624 | http://purl.obolibrary.org/obo/GO_0035825 | denotes | homologous recombination |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T53 | 0-45 | Sentence | denotes | Primary reservoirs and hosts of coronaviruses |
| T54 | 46-187 | Sentence | denotes | The source of origination and transmission are important to be determined in order to develop preventive strategies to contain the infection. |
| T55 | 188-311 | Sentence | denotes | In the case of SARS-CoV, the researchers initially focused on raccoon dogs and palm civets as a key reservoir of infection. |
| T56 | 312-492 | Sentence | denotes | However, only the samples isolated from the civets at the food market showed positive results for viral RNA detection, suggesting that the civet palm might be secondary hosts [15]. |
| T57 | 493-660 | Sentence | denotes | In 2001 the samples were isolated from the healthy persons of Hongkong and the molecular assessment showed 2.5% frequency rate of anti-bodies against SARS-coronavirus. |
| T58 | 661-781 | Sentence | denotes | These indications suggested that SARS-coronavirus may be circulating in humans before causing the outbreak in 2003 [16]. |
| T59 | 782-916 | Sentence | denotes | Later on, Rhinolophus bats were also found to have anti-SARS-CoV antibodies suggesting the bats as a source of viral replication [17]. |
| T60 | 917-1015 | Sentence | denotes | The Middle East respiratory syndrome (MERS) coronavirus first emerged in 2012 in Saudi Arabia [9]. |
| T61 | 1016-1127 | Sentence | denotes | MERS-coronavirus also pertains to beta-coronavirus and having camels as a zoonotic source or primary host [18]. |
| T62 | 1128-1310 | Sentence | denotes | In a recent study, MERS-coronavirus was also detected in Pipistrellus and Perimyotis bats [19], proffering that bats are the key host and transmitting medium of the virus [20], [21]. |
| T63 | 1311-1579 | Sentence | denotes | Initially, a group of researchers suggested snakes be the possible host, however, after genomic similarity findings of novel coronavirus with SARS-like bat viruses supported the statement that not snakes but only bats could be the key reservoirs (Table 1 ) [22], [23]. |
| T64 | 1580-1779 | Sentence | denotes | Further analysis of homologous recombination revealed that receptor binding spike glycoprotein of novel coronavirus is developed from a SARS-CoV (CoVZXC21 or CoVZC45) and a yet unknown Beta-CoV [24]. |
| T65 | 1780-1975 | Sentence | denotes | Nonetheless, to eradicate the virus, more work is required to be done in the aspects of the identification of the intermediate zoonotic source that caused the transmission of the virus to humans. |
| T66 | 1976-2055 | Sentence | denotes | Table 1 Comparative analysis of biological features of SARS-CoV and SARS-CoV-2. |
| T67 | 2056-2094 | Sentence | denotes | Features SARS-CoV SARS-CoV-2 Reference |
| T68 | 2095-2160 | Sentence | denotes | Emergence date November 2002 December 2019 [37], [79], [80], [81] |
| T69 | 2161-2208 | Sentence | denotes | Area of emergence Guangdong, China Wuhan, China |
| T70 | 2209-2262 | Sentence | denotes | Date of fully controlled July 2003 Not controlled yet |
| T71 | 2263-2326 | Sentence | denotes | Key hosts Bat, palm civets and Raccon dogs Bat [22], [82], [83] |
| T72 | 2327-2367 | Sentence | denotes | Number of countries infected 26 109 [84] |
| T73 | 2368-2437 | Sentence | denotes | Entry receptor in humans ACE2 receptor ACE2 receptor [22], [55], [85] |
| T74 | 2438-2596 | Sentence | denotes | Sign and symptoms fever, malaise, myalgia, headache, diarrhoea, shivering, cough and shortness of breath Cough, fever and shortness of breath [12], [23], [85] |
| T75 | 2597-2648 | Sentence | denotes | Disease caused SARS, ARDS SARS, COVID-19 [85], [86] |
| T76 | 2649-2689 | Sentence | denotes | Total infected patients 8098 123882 [84] |
| T77 | 2690-2725 | Sentence | denotes | Total recovered patients 7322 67051 |
| T78 | 2726-2799 | Sentence | denotes | Total died patients 776 (9.6% mortality rate) 4473 (3.61% mortality rate) |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T12 | 2456-2461 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T13 | 2463-2470 | Phenotype | denotes | malaise | http://purl.obolibrary.org/obo/HP_0012378 |
| T14 | 2472-2479 | Phenotype | denotes | myalgia | http://purl.obolibrary.org/obo/HP_0003326 |
| T15 | 2481-2489 | Phenotype | denotes | headache | http://purl.obolibrary.org/obo/HP_0002315 |
| T16 | 2491-2500 | Phenotype | denotes | diarrhoea | http://purl.obolibrary.org/obo/HP_0002014 |
| T17 | 2502-2511 | Phenotype | denotes | shivering | http://purl.obolibrary.org/obo/HP_0025144 |
| T18 | 2513-2518 | Phenotype | denotes | cough | http://purl.obolibrary.org/obo/HP_0012735 |
| T19 | 2523-2542 | Phenotype | denotes | shortness of breath | http://purl.obolibrary.org/obo/HP_0002098 |
| T20 | 2543-2548 | Phenotype | denotes | Cough | http://purl.obolibrary.org/obo/HP_0012735 |
| T21 | 2550-2555 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T22 | 2560-2579 | Phenotype | denotes | shortness of breath | http://purl.obolibrary.org/obo/HP_0002098 |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T191 | 32-45 | NCBITaxon:11118 | denotes | coronaviruses |
| T192 | 203-211 | SP_10 | denotes | SARS-CoV |
| T193 | 258-262 | NCBITaxon:9615 | denotes | dogs |
| T194 | 267-278 | SP_5 | denotes | palm civets |
| T195 | 370-374 | CHEBI:33290;CHEBI:33290 | denotes | food |
| T196 | 410-415 | NCBITaxon:10239 | denotes | viral |
| T197 | 544-551 | NCBITaxon:1 | denotes | persons |
| T198 | 643-647 | SP_10 | denotes | SARS |
| T199 | 648-659 | NCBITaxon:11118 | denotes | coronavirus |
| T200 | 694-698 | SP_10 | denotes | SARS |
| T201 | 699-710 | NCBITaxon:11118 | denotes | coronavirus |
| T202 | 733-739 | NCBITaxon:9606 | denotes | humans |
| T203 | 792-803 | SP_2;NCBITaxon:7729 | denotes | Rhinolophus |
| T204 | 804-808 | SP_2;NCBITaxon:9397 | denotes | bats |
| T205 | 838-846 | SP_10 | denotes | SARS-CoV |
| T206 | 847-857 | GO:0042571 | denotes | antibodies |
| T207 | 873-877 | SP_2;NCBITaxon:9397 | denotes | bats |
| T208 | 893-898 | NCBITaxon:10239;GO:0006260 | denotes | viral |
| T209 | 899-910 | GO:0006260 | denotes | replication |
| T210 | 933-944 | UBERON:0001004 | denotes | respiratory |
| T211 | 955-959 | SP_9 | denotes | MERS |
| T212 | 961-972 | NCBITaxon:11118 | denotes | coronavirus |
| T213 | 1016-1020 | SP_9 | denotes | MERS |
| T214 | 1021-1032 | NCBITaxon:11118 | denotes | coronavirus |
| T215 | 1055-1066 | NCBITaxon:11118 | denotes | coronavirus |
| T216 | 1147-1151 | SP_9 | denotes | MERS |
| T217 | 1152-1163 | NCBITaxon:11118 | denotes | coronavirus |
| T218 | 1185-1197 | NCBITaxon:7668 | denotes | Pipistrellus |
| T219 | 1202-1212 | NCBITaxon:42413 | denotes | Perimyotis |
| T220 | 1213-1217 | SP_2;NCBITaxon:9397 | denotes | bats |
| T221 | 1240-1244 | SP_2;NCBITaxon:9397 | denotes | bats |
| T222 | 1293-1298 | NCBITaxon:10239 | denotes | virus |
| T223 | 1399-1406 | SO:0001026 | denotes | genomic |
| T224 | 1436-1447 | NCBITaxon:11118 | denotes | coronavirus |
| T225 | 1453-1457 | SP_10 | denotes | SARS |
| T226 | 1463-1466 | SP_2 | denotes | bat |
| T227 | 1467-1474 | NCBITaxon:10239 | denotes | viruses |
| T228 | 1524-1528 | SP_2;NCBITaxon:6960 | denotes | bats |
| T229 | 1656-1661 | PG_18;PG_1 | denotes | spike |
| T230 | 1662-1674 | PG_18;PG_1;CHEBI:17089;BV_11;CHEBI:17089 | denotes | glycoprotein |
| T231 | 1684-1695 | NCBITaxon:11118 | denotes | coronavirus |
| T232 | 1716-1724 | SP_10 | denotes | SARS-CoV |
| T233 | 1810-1815 | NCBITaxon:10239 | denotes | virus |
| T234 | 1959-1964 | NCBITaxon:10239 | denotes | virus |
| T235 | 1968-1974 | NCBITaxon:9606 | denotes | humans |
| T244 | 2019-2027 | SO:0000110 | denotes | features |
| T245 | 2031-2039 | SP_10 | denotes | SARS-CoV |
| T246 | 2044-2054 | SP_7 | denotes | SARS-CoV-2 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32257431-16140765-54950080 | 488-490 | 16140765 | denotes | 15 |
| 32257431-15030679-54950081 | 777-779 | 15030679 | denotes | 16 |
| 32257431-17451830-54950082 | 912-914 | 17451830 | denotes | 17 |
| 32257431-23718156-54950083 | 1012-1013 | 23718156 | denotes | 9 |
| 32257431-29239118-54950084 | 1123-1125 | 29239118 | denotes | 18 |
| 32257431-23622767-54950085 | 1219-1221 | 23622767 | denotes | 19 |
| 32257431-22993147-54950086 | 1300-1302 | 22993147 | denotes | 20 |
| 32257431-23720729-54950087 | 1306-1308 | 23720729 | denotes | 21 |
| 32257431-31987001-54950088 | 1775-1777 | 31987001 | denotes | 24 |
| 32257431-12782660-54950089 | 2151-2153 | 12782660 | denotes | 80 |
| 32257431-14662982-54950090 | 2434-2436 | 14662982 | denotes | 85 |
| 32257431-14662982-54950091 | 2593-2595 | 14662982 | denotes | 85 |
| 32257431-14662982-54950092 | 2639-2641 | 14662982 | denotes | 85 |