PMC:7113449 / 3394-4836
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 75 | 387-394 | Species | denotes | patient | Tax:9606 |
| 76 | 567-577 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 77 | 664-672 | Species | denotes | patients | Tax:9606 |
| 78 | 760-788 | Species | denotes | Human Immunodeficiency Virus | Tax:12721 |
| 79 | 790-793 | Species | denotes | HIV | Tax:12721 |
| 80 | 846-849 | Species | denotes | HIV | Tax:12721 |
| 81 | 906-909 | Species | denotes | HIV | Tax:12721 |
| 82 | 935-950 | Chemical | denotes | dextran sulfate | MESH:D016264 |
| 83 | 1115-1122 | Chemical | denotes | steroid | MESH:D013256 |
| 84 | 1192-1199 | Chemical | denotes | steroid | MESH:D013256 |
| 85 | 340-348 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 86 | 637-646 | Disease | denotes | pneumonia | MESH:D011014 |
| 87 | 655-663 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 88 | 1169-1177 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 89 | 1307-1325 | Disease | denotes | pulmonary fibrosis | MESH:D011658 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T5 | 737-747 | Body_part | denotes | nucleotide | http://purl.org/sig/ont/fma/fma82740 |
| T6 | 790-793 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T7 | 846-849 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T8 | 906-909 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T9 | 1049-1053 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T40 | 0-2 | Disease | denotes | HP | http://purl.obolibrary.org/obo/MONDO_0004553 |
| T41 | 309-311 | Disease | denotes | HP | http://purl.obolibrary.org/obo/MONDO_0004553 |
| T42 | 340-348 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T43 | 432-434 | Disease | denotes | HP | http://purl.obolibrary.org/obo/MONDO_0004553 |
| T44 | 567-575 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T45 | 637-646 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T46 | 655-663 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T47 | 766-782 | Disease | denotes | Immunodeficiency | http://purl.obolibrary.org/obo/MONDO_0021094 |
| T48 | 1169-1177 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T49 | 1307-1325 | Disease | denotes | pulmonary fibrosis | http://purl.obolibrary.org/obo/MONDO_0002771 |
| T50 | 1439-1441 | Disease | denotes | HP | http://purl.obolibrary.org/obo/MONDO_0004553 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T32 | 0-2 | http://purl.obolibrary.org/obo/CLO_0003797 | denotes | HP |
| T33 | 0-2 | http://purl.obolibrary.org/obo/PR_000008725 | denotes | HP |
| T34 | 3-6 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T35 | 309-311 | http://purl.obolibrary.org/obo/CLO_0003797 | denotes | HP |
| T36 | 309-311 | http://purl.obolibrary.org/obo/PR_000008725 | denotes | HP |
| T37 | 432-434 | http://purl.obolibrary.org/obo/CLO_0003797 | denotes | HP |
| T38 | 432-434 | http://purl.obolibrary.org/obo/PR_000008725 | denotes | HP |
| T39 | 485-490 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T40 | 760-765 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | Human |
| T41 | 783-788 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | Virus |
| T42 | 1027-1032 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T43 | 1439-1441 | http://purl.obolibrary.org/obo/CLO_0003797 | denotes | HP |
| T44 | 1439-1441 | http://purl.obolibrary.org/obo/PR_000008725 | denotes | HP |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T7 | 0-2 | Chemical | denotes | HP | http://purl.obolibrary.org/obo/CHEBI_74055 |
| T8 | 309-311 | Chemical | denotes | HP | http://purl.obolibrary.org/obo/CHEBI_74055 |
| T9 | 432-434 | Chemical | denotes | HP | http://purl.obolibrary.org/obo/CHEBI_74055 |
| T10 | 476-483 | Chemical | denotes | antigen | http://purl.obolibrary.org/obo/CHEBI_59132 |
| T11 | 714-723 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T12 | 737-747 | Chemical | denotes | nucleotide | http://purl.obolibrary.org/obo/CHEBI_36976 |
| T13 | 748-758 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T14 | 795-805 | Chemical | denotes | nucleoside | http://purl.obolibrary.org/obo/CHEBI_33838 |
| T15 | 806-837 | Chemical | denotes | reverse transcriptase inhibitor | http://purl.obolibrary.org/obo/CHEBI_53756|http://purl.obolibrary.org/obo/CHEBI_59897 |
| T17 | 814-837 | Chemical | denotes | transcriptase inhibitor | http://purl.obolibrary.org/obo/CHEBI_37416 |
| T18 | 828-837 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T19 | 854-864 | Chemical | denotes | nucleoside | http://purl.obolibrary.org/obo/CHEBI_33838 |
| T20 | 865-896 | Chemical | denotes | reverse transcriptase inhibitor | http://purl.obolibrary.org/obo/CHEBI_53756|http://purl.obolibrary.org/obo/CHEBI_59897 |
| T22 | 873-896 | Chemical | denotes | transcriptase inhibitor | http://purl.obolibrary.org/obo/CHEBI_37416 |
| T23 | 887-896 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T24 | 906-928 | Chemical | denotes | HIV protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_35660 |
| T25 | 910-928 | Chemical | denotes | protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258 |
| T27 | 919-928 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T28 | 930-932 | Chemical | denotes | PI | http://purl.obolibrary.org/obo/CHEBI_28874|http://purl.obolibrary.org/obo/CHEBI_53806|http://purl.obolibrary.org/obo/CHEBI_61484|http://purl.obolibrary.org/obo/CHEBI_74790|http://purl.obolibrary.org/obo/CHEBI_37670 |
| T33 | 935-950 | Chemical | denotes | dextran sulfate | http://purl.obolibrary.org/obo/CHEBI_34674 |
| T34 | 935-942 | Chemical | denotes | dextran | http://purl.obolibrary.org/obo/CHEBI_52071 |
| T35 | 943-950 | Chemical | denotes | sulfate | http://purl.obolibrary.org/obo/CHEBI_16189 |
| T36 | 1115-1122 | Chemical | denotes | steroid | http://purl.obolibrary.org/obo/CHEBI_35341 |
| T37 | 1192-1199 | Chemical | denotes | steroid | http://purl.obolibrary.org/obo/CHEBI_35341 |
| T38 | 1439-1441 | Chemical | denotes | HP | http://purl.obolibrary.org/obo/CHEBI_74055 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T10 | 159-171 | http://purl.obolibrary.org/obo/GO_0009405 | denotes | pathogenesis |
| T11 | 521-536 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
| T12 | 814-827 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | transcriptase |
| T13 | 814-827 | http://purl.obolibrary.org/obo/GO_0003899 | denotes | transcriptase |
| T14 | 873-886 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | transcriptase |
| T15 | 873-886 | http://purl.obolibrary.org/obo/GO_0003899 | denotes | transcriptase |
| T16 | 1382-1400 | http://purl.obolibrary.org/obo/GO_0006956 | denotes | complement cascade |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T25 | 0-119 | Sentence | denotes | HP has been reported in the literature for the past several decades, but its pathophysiology remains poorly understood. |
| T26 | 120-222 | Sentence | denotes | The possibility of obtaining the exact pathogenesis is less with the current knowledge and technology. |
| T27 | 223-419 | Sentence | denotes | Considering our current understanding of the pathophysiology and clinical features of HP, the treatment strategy for COVID-19 needs to be tailored according to the patient's age and immune status. |
| T28 | 420-566 | Sentence | denotes | Traditional HP treatment methods such as decreasing the antigen (virus) and controlling the abnormal immune response must be part of the strategy. |
| T29 | 567-647 | Sentence | denotes | SARS-CoV-2 is more likely to spread in the elderly and lead to severe pneumonia. |
| T30 | 648-1076 | Sentence | denotes | Hence, COVID-19 patients would benefit from the administration of antiviral medications (nucleotide inhibitors, Human Immunodeficiency Virus (HIV) nucleoside reverse transcriptase inhibitor (NRTI), HIV non-nucleoside reverse transcriptase inhibitor (NNRTI), HIV protease inhibitor (PI), dextran sulfate, and combination therapy, etc.) that will limit the spread of less virulent virus both within the body and in the population. |
| T31 | 1077-1326 | Sentence | denotes | Prophylactic and therapeutic low dose steroid oral tablets/inhalers at the earlier stage of COVID-19 and high dose steroid treatment according to the severity of the disease can play important roles in decreasing the fatality and pulmonary fibrosis. |
| T32 | 1327-1442 | Sentence | denotes | Additionally, safer treatment options that control the complement cascade could be considered in cases of acute HP. |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T16 | 0-2 | Phenotype | denotes | HP | http://purl.obolibrary.org/obo/HP_0006516 |
| T17 | 309-311 | Phenotype | denotes | HP | http://purl.obolibrary.org/obo/HP_0006516 |
| T18 | 432-434 | Phenotype | denotes | HP | http://purl.obolibrary.org/obo/HP_0006516 |
| T19 | 637-646 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T20 | 766-782 | Phenotype | denotes | Immunodeficiency | http://purl.obolibrary.org/obo/HP_0002721 |
| T21 | 1307-1325 | Phenotype | denotes | pulmonary fibrosis | http://purl.obolibrary.org/obo/HP_0002206 |
| T22 | 1439-1441 | Phenotype | denotes | HP | http://purl.obolibrary.org/obo/HP_0006516 |