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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7111504","sourcedb":"PMC","sourceid":"7111504","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7111504","text":"It is worth noting that in general predicting immunogenicity of given a peptide is challenging and not a fully solved problem, and therefore current models for predicting immunogenicity are suboptimal. iPred is also not an exception. In fact, we could see that a substantial number of IEDB immunogenic peptides were scored \u003c 0.5 (the threshold score used to classify immunogenic vs non-immunogenic). This led us to ask whether we can gather any other evidence of either immunogenicity or cross-reactivity.","tracks":[{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T105","span":{"begin":46,"end":60},"obj":"BV_15"},{"id":"T106","span":{"begin":171,"end":185},"obj":"BV_15"},{"id":"T107","span":{"begin":290,"end":301},"obj":"CHEBI:60816;CHEBI:60816"},{"id":"T108","span":{"begin":367,"end":378},"obj":"CHEBI:60816;CHEBI:60816"},{"id":"T109","span":{"begin":386,"end":397},"obj":"CHEBI:60816;CHEBI:60816"},{"id":"T110","span":{"begin":470,"end":484},"obj":"BV_15"},{"id":"T34290","span":{"begin":46,"end":60},"obj":"BV_15"},{"id":"T17780","span":{"begin":171,"end":185},"obj":"BV_15"},{"id":"T91242","span":{"begin":290,"end":301},"obj":"CHEBI:60816;CHEBI:60816"},{"id":"T28529","span":{"begin":367,"end":378},"obj":"CHEBI:60816;CHEBI:60816"},{"id":"T28382","span":{"begin":386,"end":397},"obj":"CHEBI:60816;CHEBI:60816"},{"id":"T58994","span":{"begin":470,"end":484},"obj":"BV_15"}],"attributes":[{"subj":"T105","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T106","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T107","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T108","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T109","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T110","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T34290","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T17780","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T91242","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T28529","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T28382","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T58994","pred":"source","obj":"LitCovid-PMC-OGER-BB"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T131","span":{"begin":70,"end":71},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T132","span":{"begin":72,"end":79},"obj":"http://purl.obolibrary.org/obo/PR_000018263"},{"id":"T133","span":{"begin":103,"end":104},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T134","span":{"begin":261,"end":262},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T135","span":{"begin":302,"end":310},"obj":"http://purl.obolibrary.org/obo/PR_000018263"},{"id":"T136","span":{"begin":415,"end":418},"obj":"http://purl.obolibrary.org/obo/CLO_0001755"}],"attributes":[{"subj":"T131","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T132","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T133","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T134","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T135","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T136","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T72","span":{"begin":72,"end":79},"obj":"Chemical"},{"id":"T73","span":{"begin":302,"end":310},"obj":"Chemical"}],"attributes":[{"id":"A72","pred":"chebi_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"},{"id":"A73","pred":"chebi_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"},{"subj":"T72","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T73","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T112","span":{"begin":0,"end":233},"obj":"Sentence"},{"id":"T113","span":{"begin":234,"end":399},"obj":"Sentence"},{"id":"T114","span":{"begin":400,"end":505},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T112","pred":"source","obj":"LitCovid-sentences"},{"subj":"T113","pred":"source","obj":"LitCovid-sentences"},{"subj":"T114","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PMC-OGER-BB","color":"#93ece4","default":true},{"id":"LitCovid-PD-CLO","color":"#ecca93"},{"id":"LitCovid-PD-CHEBI","color":"#b093ec"},{"id":"LitCovid-sentences","color":"#93ec96"}]}]}}