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PMC:7111504 / 628-1503
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
24 | 686-689 | Gene | denotes | TCR | Gene:6962 |
25 | 134-156 | Species | denotes | 2019 novel coronavirus | Tax:2697049 |
26 | 158-167 | Species | denotes | 2019-nCoV | Tax:2697049 |
27 | 209-213 | Species | denotes | nCoV | Tax:2697049 |
28 | 236-289 | Species | denotes | Severe acute respiratory syndrome-related coronavirus | Tax:694009 |
29 | 291-299 | Species | denotes | SARS CoV | Tax:694009 |
30 | 396-400 | Species | denotes | nCoV | Tax:2697049 |
31 | 561-570 | Species | denotes | 2019-nCoV | Tax:2697049 |
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T13 | 71-82 | CHEBI:60816;CHEBI:60816 | denotes | immunogenic |
T14 | 145-156 | NCBITaxon:11118 | denotes | coronavirus |
T15 | 158-167 | SP_7 | denotes | 2019-nCoV |
T16 | 249-260 | UBERON:0001004 | denotes | respiratory |
T17 | 278-289 | NCBITaxon:11118 | denotes | coronavirus |
T18 | 291-299 | SP_10 | denotes | SARS CoV |
T19 | 341-352 | CHEBI:60816;CHEBI:60816 | denotes | immunogenic |
T20 | 356-362 | CL:0000084;BV_23 | denotes | T cell |
T21 | 363-369 | BV_23 | denotes | assays |
T22 | 450-461 | CHEBI:60816;CHEBI:60816 | denotes | immunogenic |
T23 | 495-502 | BV_9 | denotes | Epitope |
T24 | 561-570 | SP_7 | denotes | 2019-nCoV |
T25 | 613-620 | SO:0001023 | denotes | alleles |
T26 | 669-675 | CL:0000084 | denotes | T Cell |
T27 | 768-782 | BV_15 | denotes | immunogenicity |
T28 | 849-863 | BV_15 | denotes | immunogenicity |
T88509 | 71-82 | CHEBI:60816;CHEBI:60816 | denotes | immunogenic |
T79155 | 145-156 | NCBITaxon:11118 | denotes | coronavirus |
T74980 | 158-167 | SP_7 | denotes | 2019-nCoV |
T79472 | 249-260 | UBERON:0001004 | denotes | respiratory |
T72088 | 278-289 | NCBITaxon:11118 | denotes | coronavirus |
T78785 | 291-299 | SP_10 | denotes | SARS CoV |
T6187 | 341-352 | CHEBI:60816;CHEBI:60816 | denotes | immunogenic |
T6838 | 356-362 | CL:0000084;BV_23 | denotes | T cell |
T61854 | 363-369 | BV_23 | denotes | assays |
T23618 | 450-461 | CHEBI:60816;CHEBI:60816 | denotes | immunogenic |
T65792 | 495-502 | BV_9 | denotes | Epitope |
T43750 | 561-570 | SP_7 | denotes | 2019-nCoV |
T71761 | 613-620 | SO:0001023 | denotes | alleles |
T45031 | 669-675 | CL:0000084 | denotes | T Cell |
T11574 | 768-782 | BV_15 | denotes | immunogenicity |
T5154 | 849-863 | BV_15 | denotes | immunogenicity |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T2 | 358-362 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T3 | 609-612 | Body_part | denotes | HLA | http://purl.org/sig/ont/fma/fma84795 |
T4 | 671-675 | Body_part | denotes | Cell | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 236-269 | Disease | denotes | Severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
T2 | 291-295 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10 | 47-48 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T11 | 83-91 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
T12 | 214-222 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
T13 | 356-362 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cell |
T14 | 393-395 | http://purl.obolibrary.org/obo/CLO_0001382 | denotes | 48 |
T15 | 401-409 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
T16 | 417-418 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T17 | 462-470 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
T18 | 541-542 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T19 | 577-585 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
T20 | 669-675 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T Cell |
T21 | 747-748 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T22 | 828-836 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
T23 | 842-843 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T3 | 83-91 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
T4 | 214-222 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
T5 | 401-409 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
T6 | 462-470 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
T7 | 577-585 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
T8 | 828-836 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11 | 0-8 | Sentence | denotes | Results: |
T12 | 9-189 | Sentence | denotes | We report in silico identification of a comprehensive list of immunogenic peptides that can be used as potential targets for 2019 novel coronavirus (2019-nCoV) vaccine development. |
T13 | 190-370 | Sentence | denotes | First, we found 28 nCoV peptides identical to Severe acute respiratory syndrome-related coronavirus (SARS CoV) that have previously been characterized immunogenic by T cell assays. |
T14 | 371-519 | Sentence | denotes | Second, we identified 48 nCoV peptides having a high degree of similarity with immunogenic peptides deposited in The Immune Epitope Database (IEDB). |
T15 | 520-874 | Sentence | denotes | Lastly, we conducted a de novo search of 2019-nCoV 9-mer peptides that i) bind to common HLA alleles in Chinese and European population and ii) have T Cell Receptor (TCR) recognition potential by positional weight matrices and a recently developed immunogenicity algorithm, iPred, and identified in total 63 peptides with a high immunogenicity potential. |