PMC:7110296 / 16973-18815 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T272","span":{"begin":152,"end":157},"obj":"PR:000004516"},{"id":"T273","span":{"begin":185,"end":190},"obj":"PR:000004516"},{"id":"T274","span":{"begin":202,"end":215},"obj":"CHEBI:35222;CHEBI:35222"},{"id":"T275","span":{"begin":568,"end":586},"obj":"DG_49"},{"id":"T276","span":{"begin":936,"end":949},"obj":"DG_23"},{"id":"T277","span":{"begin":954,"end":966},"obj":"DG_30"},{"id":"T278","span":{"begin":1189,"end":1204},"obj":"DG_29"},{"id":"T279","span":{"begin":1686,"end":1692},"obj":"UBERON:0002113"},{"id":"T280","span":{"begin":1707,"end":1712},"obj":"PR:000013883"},{"id":"T281","span":{"begin":1725,"end":1736},"obj":"CHEBI:27584;CHEBI:27584"},{"id":"T282","span":{"begin":1750,"end":1760},"obj":"CHEBI:35222;CHEBI:35222"},{"id":"T283","span":{"begin":1799,"end":1808},"obj":"CHEBI:35222;CHEBI:35222"}],"text":"Table 4 Medications used on admission and during hospitalization\nDrugs Medications on admission Medications during hospitalization\nAll patients AKI Non-AKI P value All patients AKI Non-AKI P value\nRAAS inhibitors 33 of 701 (4.7) 0 of 36 (0.0) 33 of 665 (5.0) 0.334 41 of 701 (5.8) 0 of 36 (0.0) 41 of 665 (6.2) 0.242\nAntibiotics 498 of 701 (71.0) 27 of 36 (75.0) 471 of 665 (70.8) 0.591 600 of 701 (85.6) 35 of 36 (97.2) 565 of 665 (85.0) 0.041\nAntivirals 512 of 701 (73.0) 21 of 36 (58.3) 491 of 665 (73.8) 0.041 658 of 701 (93.9) 32 of 36 (88.9) 626 of 665 (94.1) 0.357\nUmifenovir 343 of 701 (48.9) 14 of 36 (38.9) 329 of 665 (49.5) 0.216 475 of 701 (67.8) 17 of 36 (47.2) 458 of 665 (68.9) 0.007\nGanciclovir 24 of 701 (3.4) 0 of 36 (0.0) 24 of 665 (3.6) 0.491 27 of 701 (3.9) 0 of 36 (0.0) 27 of 665 (4.1) 0.430\nInterferon 129 of 701 (18.4) 6 of 36 (16.7) 123 of 665 (18.5) 0.783 169 of 701 (24.1) 9 of 36 (25.0) 160 of 665 (24.1) 0.898\nLopinavir and ritonavir 74 of 701 (10.6) 2 of 36 (5.6) 72 of 665 (10.8) 0.469 196 of 701 (28.0) 4 of 36 (11.1) 192 of 665 (28.9) 0.021\nOseltamivir 39 of 701 (5.6) 1 of 36 (2.8) 38 of 665 (5.7) 0.707 79 of 701 (11.3) 1 of 36 (2.8) 78 of 665 (11.7) 0.166\nRibavirin 8 of 701 (1.1) 0 of 36 (0.0) 8 of 665 (1.2) 1.000 33 of 701 (4.7) 0 of 36 (0.0) 33 of 665 (5.0) 0.334\nAntidiabetic 68 of 701 (9.7) 3 of 36 (8.3) 65 of 665 (9.8) 1.000 119 of 701 (17.0) 4 of 36 (11.1) 115 of 665 (17.3) 0.336\nDiuretics 10 of 701 (1.4) 1 of 36 (2.8) 9 of 665 (1.4) 0.412 67 of 701 (9.6) 26 of 36 (72.2) 41 of 665 (6.2) \u003c0.001\nGlucocorticoids 259 of 701 (36.9) 21 of 36 (58.3) 238 of 665 (35.8) 0.006 387 of 701 (55.2) 22 of 36 (61.1) 365 of 665 (54.9) 0.465\nAKI, acute kidney injury; RAAS, renin-angiotensin-aldosterone system.\nRAAS inhibitors include angiotensin-converting-enzyme inhibitor and angiotensin receptor blocker."}