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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7108609","sourcedb":"PMC","sourceid":"7108609","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7108609","text":"In order to put this hypothesis to the test, we used a cell binding assay that reconstitutes the interaction between the S protein and ACE2 (Chou et al. 2005). We present data indicating that the S protein/ACE2-mediated adhesion between cells expressing ACE2 and cells coexpressing the S protein and the A histo-blood group antigen can be specifically blocked by anti-A antibodies. To further evaluate the potential effect of the ABO polymorphism on the epidemiology of SARS, we present a model of its transmission dynamics that takes into account the effect of the protection by anti-histo-blood group natural antibodies.","tracks":[{"project":"2_test","denotations":[{"id":"18818423-15582697-45167054","span":{"begin":153,"end":157},"obj":"15582697"},{"id":"T94480","span":{"begin":153,"end":157},"obj":"15582697"}],"attributes":[{"subj":"18818423-15582697-45167054","pred":"source","obj":"2_test"},{"subj":"T94480","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#9396ec","default":true}]}]}}