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PMC:7105881 / 75-2134 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
38 6-19 Species denotes coronaviruses Tax:11118
39 21-25 Species denotes CoVs Tax:11118
40 51-57 Species denotes humans Tax:9606
41 104-108 Species denotes CoVs Tax:11118
42 120-165 Species denotes severe acute respiratory syndrome coronavirus Tax:694009
43 167-175 Species denotes SARS-CoV Tax:694009
44 178-233 Species denotes Middle East respiratory syndrome coronavirus (MERS-CoV) Tax:1335626
45 329-335 Species denotes humans Tax:9606
46 411-417 Species denotes humans Tax:9606
47 521-527 Species denotes humans Tax:9606
48 617-626 Species denotes 2019-nCoV Tax:2697049
49 718-724 Species denotes people Tax:9606
50 768-776 Species denotes SARS-CoV Tax:694009
51 781-789 Species denotes MERS-CoV Tax:1335626
52 913-918 Species denotes human Tax:9606
53 971-980 Species denotes 2019-nCoV Tax:2697049
54 1040-1047 Species denotes new CoV Tax:2697049
55 1146-1154 Species denotes SARS-CoV Tax:694009
56 1159-1167 Species denotes MERS-CoV Tax:1335626
57 1211-1217 Species denotes humans Tax:9606
58 1308-1313 Species denotes human Tax:9606
59 1314-1318 Species denotes CoVs Tax:11118
60 1381-1389 Species denotes SARS-CoV Tax:694009
61 1394-1402 Species denotes MERS-CoV Tax:1335626
62 1484-1489 Species denotes human Tax:9606
63 1490-1494 Species denotes CoVs Tax:11118
64 1851-1860 Species denotes 2019-nCoV Tax:2697049
65 1876-1880 Species denotes CoVs Tax:11118
66 258-261 Species denotes CoV Tax:11118
67 263-272 Species denotes 2019-nCoV Tax:2697049
68 315-325 Disease denotes infections MESH:D007239
69 389-407 Disease denotes SARS-CoV infection MESH:C000657245
70 504-517 Disease denotes CoV infection MESH:D018352
71 794-802 Disease denotes zoonotic MESH:D015047
72 919-929 Disease denotes infections MESH:D007239
73 1132-1142 Disease denotes infections MESH:D007239

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 1287-1295 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T2 1572-1579 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T3 1622-1629 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T4 1662-1670 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 120-153 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T2 167-175 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T3 315-328 Disease denotes infections in http://purl.obolibrary.org/obo/MONDO_0005550
T4 389-407 Disease denotes SARS-CoV infection http://purl.obolibrary.org/obo/MONDO_0005091
T5 398-407 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T6 508-517 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T7 768-776 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T8 919-929 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T9 1132-1142 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T10 1146-1154 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T11 1381-1389 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T2 51-57 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T3 239-240 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T4 329-335 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T5 411-417 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T6 521-527 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T7 803-810 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T8 818-822 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bats
T9 913-918 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T10 1082-1083 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T11 1182-1185 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T12 1211-1217 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T13 1308-1313 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T14 1484-1489 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T15 1971-1978 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Viruses

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 1287-1295 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T2 1572-1579 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T3 1622-1629 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T4 1662-1670 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 308-325 Phenotype denotes severe infections http://purl.obolibrary.org/obo/HP_0032169

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T3 0-65 Sentence denotes Seven coronaviruses (CoVs) have been isolated from humans so far.
T4 66-388 Sentence denotes Among them, three emerging pathogenic CoVs, including severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and a newly identified CoV (2019-nCoV), once caused or continue to cause severe infections in humans, posing significant threats to global public health.
T5 389-616 Sentence denotes SARS-CoV infection in humans (with about 10% case fatality rate) was first reported from China in 2002, while MERS-CoV infection in humans (with about 34.4% case fatality rate) was first reported from Saudi Arabia in June 2012.
T6 617-762 Sentence denotes 2019-nCoV was first reported from China in December 2019, and is currently infecting more than 70000 people (with about 2.7% case fatality rate).
T7 763-930 Sentence denotes Both SARS-CoV and MERS-CoV are zoonotic viruses, using bats as their natural reservoirs, and then transmitting through intermediate hosts, leading to human infections.
T8 931-1072 Sentence denotes Nevertheless, the intermediate host for 2019-nCoV is still under investigation and the vaccines against this new CoV have not been available.
T9 1073-1218 Sentence denotes Although a variety of vaccines have been developed against infections of SARS-CoV and MERS-CoV, none of them has been approved for use in humans.
T10 1219-1495 Sentence denotes In this review, we have described the structure and function of key proteins of emerging human CoVs, overviewed the current vaccine types to be developed against SARS-CoV and MERS-CoV, and summarized recent advances in subunit vaccines against these two pathogenic human CoVs.
T11 1496-1752 Sentence denotes These subunit vaccines are introduced on the basis of full-length spike (S) protein, receptor-binding domain (RBD), non-RBD S protein fragments, and non-S structural proteins, and the potential factors affecting these subunit vaccines are also illustrated.
T12 1753-1905 Sentence denotes Overall, this review will be helpful for rapid design and development of vaccines against the new 2019-nCoV and any future CoVs with pandemic potential.
T13 1906-1979 Sentence denotes This review was written for the topic of Antivirals for Emerging Viruses:
T14 1980-2059 Sentence denotes Vaccines and Therapeutics in the Virology section of Frontiers in Microbiology.

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T3 6-19 NCBITaxon:11118 denotes coronaviruses
T4 51-57 NCBITaxon:9606 denotes humans
T5 120-132 SP_10 denotes severe acute
T6 133-144 SP_10;UBERON:0001004 denotes respiratory
T7 145-165 SP_10 denotes syndrome coronavirus
T8 167-175 SP_10 denotes SARS-CoV
T9 178-189 SP_9 denotes Middle East
T10 190-201 SP_9;UBERON:0001004 denotes respiratory
T11 202-222 SP_9 denotes syndrome coronavirus
T12 224-232 SP_9 denotes MERS-CoV
T13 263-272 SP_7 denotes 2019-nCoV
T14 329-335 NCBITaxon:9606 denotes humans
T15 389-397 SP_10 denotes SARS-CoV
T16 411-417 NCBITaxon:9606 denotes humans
T17 499-507 SP_9 denotes MERS-CoV
T18 521-527 NCBITaxon:9606 denotes humans
T19 617-626 SP_7 denotes 2019-nCoV
T20 718-724 NCBITaxon:9606 denotes people
T21 768-776 SP_10 denotes SARS-CoV
T22 781-789 SP_9 denotes MERS-CoV
T23 803-810 NCBITaxon:10239 denotes viruses
T24 818-822 SP_2;NCBITaxon:6960 denotes bats
T25 913-918 SP_6;NCBITaxon:9606 denotes human
T26 971-980 SP_7 denotes 2019-nCoV
T27 1146-1154 SP_10 denotes SARS-CoV
T28 1159-1167 SP_9 denotes MERS-CoV
T29 1211-1217 NCBITaxon:9606 denotes humans
T30 1308-1313 SP_6;NCBITaxon:9606 denotes human
T31 1381-1389 SP_10 denotes SARS-CoV
T32 1394-1402 SP_9 denotes MERS-CoV
T33 1484-1489 SP_6;NCBITaxon:9606 denotes human
T34 1598-1604 SO:0000417 denotes domain
T35 1620-1629 PG_1 denotes S protein
T36 1851-1860 SP_7 denotes 2019-nCoV
T37 1971-1978 NCBITaxon:10239 denotes Viruses
T36628 6-19 NCBITaxon:11118 denotes coronaviruses
T19649 51-57 NCBITaxon:9606 denotes humans
T48275 120-132 SP_10 denotes severe acute
T53125 133-144 SP_10;UBERON:0001004 denotes respiratory
T63264 145-165 SP_10 denotes syndrome coronavirus
T47638 167-175 SP_10 denotes SARS-CoV
T81912 178-189 SP_9 denotes Middle East
T57284 190-201 SP_9;UBERON:0001004 denotes respiratory
T5316 202-222 SP_9 denotes syndrome coronavirus
T32993 224-232 SP_9 denotes MERS-CoV
T76811 263-272 SP_7 denotes 2019-nCoV
T78659 329-335 NCBITaxon:9606 denotes humans
T70251 389-397 SP_10 denotes SARS-CoV
T93319 411-417 NCBITaxon:9606 denotes humans
T55876 499-507 SP_9 denotes MERS-CoV
T73264 521-527 NCBITaxon:9606 denotes humans
T55869 617-626 SP_7 denotes 2019-nCoV
T67198 718-724 NCBITaxon:9606 denotes people
T95796 768-776 SP_10 denotes SARS-CoV
T29232 781-789 SP_9 denotes MERS-CoV
T37092 803-810 NCBITaxon:10239 denotes viruses
T43831 818-822 SP_2;NCBITaxon:6960 denotes bats
T95839 913-918 SP_6;NCBITaxon:9606 denotes human
T58242 971-980 SP_7 denotes 2019-nCoV
T89984 1146-1154 SP_10 denotes SARS-CoV
T56264 1159-1167 SP_9 denotes MERS-CoV
T11552 1211-1217 NCBITaxon:9606 denotes humans
T28582 1308-1313 SP_6;NCBITaxon:9606 denotes human
T48545 1381-1389 SP_10 denotes SARS-CoV
T62193 1394-1402 SP_9 denotes MERS-CoV
T56881 1484-1489 SP_6;NCBITaxon:9606 denotes human
T78790 1598-1604 SO:0000417 denotes domain
T16061 1620-1629 PG_1 denotes S protein
T29131 1851-1860 SP_7 denotes 2019-nCoV
T96476 1971-1978 NCBITaxon:10239 denotes Viruses