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PMC:7105881 / 54538-55603 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1684 71-79 Species denotes MERS-CoV Tax:1335626
1685 269-277 Species denotes MERS-CoV Tax:1335626
1686 412-416 Species denotes mice Tax:10090
1687 736-740 Species denotes mice Tax:10090
1688 802-813 Species denotes recombinant Tax:575864
1689 507-515 Chemical denotes Freund’s
1690 517-525 Chemical denotes aluminum MESH:D000535
1691 527-549 Chemical denotes Monophosphoryl lipid A MESH:C048436
1692 551-566 Chemical denotes Montanide ISA51 MESH:C477385
1693 571-575 Chemical denotes MF59 MESH:C089950
1694 754-767 Disease denotes CoV infection MESH:D018352
1695 931-944 Disease denotes CoV infection MESH:D018352

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T310 308-315 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T311 369-377 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T312 384-388 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T313 542-547 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T314 602-609 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T315 642-649 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T316 825-832 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T317 970-974 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T318 1006-1013 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T269 758-767 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T270 935-944 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T645 267-268 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T646 327-329 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T647 382-388 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T648 548-549 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T649 800-801 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T650 968-974 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T57469 146-155 Chemical denotes adjuvants http://purl.obolibrary.org/obo/CHEBI_60809
T32156 308-315 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T23740 434-442 Chemical denotes adjuvant http://purl.obolibrary.org/obo/CHEBI_60809
T82040 496-505 Chemical denotes adjuvants http://purl.obolibrary.org/obo/CHEBI_60809
T77416 517-525 Chemical denotes aluminum http://purl.obolibrary.org/obo/CHEBI_28984
T6712 542-549 Chemical denotes lipid A http://purl.obolibrary.org/obo/CHEBI_25051|http://purl.obolibrary.org/obo/CHEBI_47040|http://purl.obolibrary.org/obo/CHEBI_58712
T9414 542-547 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T76587 602-609 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T85274 642-649 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T7641 825-832 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T73438 838-842 Chemical denotes alum http://purl.obolibrary.org/obo/CHEBI_74768
T59817 851-860 Chemical denotes adjuvants http://purl.obolibrary.org/obo/CHEBI_60809
T38893 1006-1013 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T4984 1036-1045 Chemical denotes adjuvants http://purl.obolibrary.org/obo/CHEBI_60809

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T108 51-67 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T109 173-189 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses

2_test

Id Subject Object Predicate Lexical cue
32265848-25405618-36511229 221-225 25405618 denotes 2014
32265848-25640653-36511230 241-245 25640653 denotes 2016
32265848-25640653-36511231 783-787 25640653 denotes 2016
32265848-25405618-36511232 1059-1063 25405618 denotes 2014

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T294 0-247 Sentence denotes Adjuvants play an essential role in enhancing host immune responses to MERS-CoV subunit vaccines, including those based on the RBD, and different adjuvants can promote host immune responses to variant levels (Lan et al., 2014; Zhang et al., 2016).
T295 248-471 Sentence denotes For example, while a MERS-CoV RBD subunit vaccine (S377-588 protein fused with Fc) alone induced detectable neutralizing antibody and T-cell responses in immunized mice, inclusion of an adjuvant enhanced its immunogenicity.
T296 472-789 Sentence denotes Particularly, among the adjuvants (Freund’s, aluminum, Monophosphoryl lipid A, Montanide ISA51 and MF59) conjugated with this RBD protein, MF59 could best potentiate the protein to induce the highest-titer anti-S antibodies and neutralizing antibodies, protecting mice against MERS-CoV infection (Zhang et al., 2016).
T297 790-1065 Sentence denotes Moreover, a recombinant RBD (rRBD) protein plus alum and CpG adjuvants elicited the highest neutralizing antibodies against pseudotyped MERS-CoV infection, whereas the strongest T-cell responses were induced by this protein plus Freund’s and CpG adjuvants (Lan et al., 2014).

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T889 0-9 CHEBI:60809;CHEBI:60809 denotes Adjuvants
T890 51-57 UBERON:0002405;GO:0006955 denotes immune
T891 58-67 GO:0006955 denotes responses
T892 71-79 SP_9 denotes MERS-CoV
T893 146-155 CHEBI:60809;CHEBI:60809 denotes adjuvants
T894 173-179 UBERON:0002405;GO:0006955 denotes immune
T895 180-189 GO:0006955 denotes responses
T896 269-277 SP_9 denotes MERS-CoV
T897 369-377 GO:0042571 denotes antibody
T898 382-388 CL:0000084 denotes T-cell
T899 412-416 NCBITaxon:10088 denotes mice
T900 434-442 CHEBI:60809;CHEBI:60809 denotes adjuvant
T901 456-470 CHEBI:60816;CHEBI:60816;BV_15 denotes immunogenicity
T902 496-505 CHEBI:60809;CHEBI:60809 denotes adjuvants
T903 542-549 CHEBI:47040;CHEBI:47040 denotes lipid A
T904 577-587 MOP:0000779 denotes conjugated
T905 685-695 GO:0042571 denotes antibodies
T906 713-723 GO:0042571 denotes antibodies
T907 736-740 NCBITaxon:10088 denotes mice
T908 749-757 SP_9 denotes MERS-CoV
T909 851-860 CHEBI:60809;CHEBI:60809 denotes adjuvants
T910 895-905 GO:0042571 denotes antibodies
T911 926-934 SP_9 denotes MERS-CoV
T912 1036-1045 CHEBI:60809;CHEBI:60809 denotes adjuvants
T52744 0-9 CHEBI:60809;CHEBI:60809 denotes Adjuvants
T11857 51-57 UBERON:0002405;GO:0006955 denotes immune
T85159 58-67 GO:0006955 denotes responses
T26375 71-79 SP_9 denotes MERS-CoV
T98625 146-155 CHEBI:60809;CHEBI:60809 denotes adjuvants
T93717 173-179 UBERON:0002405;GO:0006955 denotes immune
T65360 180-189 GO:0006955 denotes responses
T96823 269-277 SP_9 denotes MERS-CoV
T38832 369-377 GO:0042571 denotes antibody
T55110 382-388 CL:0000084 denotes T-cell
T62891 412-416 NCBITaxon:10088 denotes mice
T6541 434-442 CHEBI:60809;CHEBI:60809 denotes adjuvant
T93532 456-470 CHEBI:60816;CHEBI:60816;BV_15 denotes immunogenicity
T57574 496-505 CHEBI:60809;CHEBI:60809 denotes adjuvants
T47385 542-549 CHEBI:47040;CHEBI:47040 denotes lipid A
T52510 577-587 MOP:0000779 denotes conjugated
T70169 685-695 GO:0042571 denotes antibodies
T65785 713-723 GO:0042571 denotes antibodies
T55866 736-740 NCBITaxon:10088 denotes mice
T88853 749-757 SP_9 denotes MERS-CoV
T95058 851-860 CHEBI:60809;CHEBI:60809 denotes adjuvants
T8567 895-905 GO:0042571 denotes antibodies
T62089 926-934 SP_9 denotes MERS-CoV
T52890 1036-1045 CHEBI:60809;CHEBI:60809 denotes adjuvants