PMC:7105881 / 49823-51254 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7105881","sourcedb":"PMC","sourceid":"7105881","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7105881","text":"Subsequently, several MERS-CoV subunit vaccines have been designed based on the identified critical neutralizing domain of RBD fragment, including those expressed in a stable CHO cell line (S377-588-Fc), fusing with a trimeric motif foldon (RBD-Fd), or containing single or multiple mutations in the RBD of representative human and camel strains from the 2012–2015 MERS outbreaks (Tai et al., 2016, 2017; Nyon et al., 2018). These RBD proteins maintain good conformation, functionality, antigenicity, and immunogenicity, with ability to bind the DPP4 receptor and RBD-specific neutralizing mAbs and to elicit robust neutralizing antibodies cross-neutralizing multiple strains of MERS pseudoviruses and live MERS-CoV (Tai et al., 2016, 2017; Nyon et al., 2018). It is noted that the wild-type MERS-CoV RBD proteins consisting of the identified critical neutralizing domain confer partial protection of hDPP4-transgenic (hDPP4-Tg) mice from MERS-CoV infection without causing immunological toxicity or eosinophilic immune enhancement (Tai et al., 2016; Wang Y. et al., 2017; Nyon et al., 2018); nevertheless, a structurally designed mutant version of such RBD protein with a non-neutralizing epitope masked (T579N) preserves intact conformation and significantly improves overall neutralizing activity and protective efficacy, resulting in the full protection of hDPP4-Tg mice against high-dose MERS-CoV challenge (Du et al., 2016a).","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"1585","span":{"begin":546,"end":550},"obj":"Gene"},{"id":"1586","span":{"begin":901,"end":906},"obj":"Gene"},{"id":"1587","span":{"begin":1361,"end":1366},"obj":"Gene"},{"id":"1588","span":{"begin":919,"end":924},"obj":"Gene"},{"id":"1589","span":{"begin":22,"end":30},"obj":"Species"},{"id":"1590","span":{"begin":322,"end":327},"obj":"Species"},{"id":"1591","span":{"begin":332,"end":337},"obj":"Species"},{"id":"1592","span":{"begin":707,"end":715},"obj":"Species"},{"id":"1593","span":{"begin":792,"end":800},"obj":"Species"},{"id":"1594","span":{"begin":929,"end":933},"obj":"Species"},{"id":"1595","span":{"begin":1370,"end":1374},"obj":"Species"},{"id":"1596","span":{"begin":1393,"end":1401},"obj":"Species"},{"id":"1597","span":{"begin":907,"end":917},"obj":"Species"},{"id":"1598","span":{"begin":944,"end":957},"obj":"Disease"},{"id":"1599","span":{"begin":974,"end":996},"obj":"Disease"},{"id":"1600","span":{"begin":175,"end":178},"obj":"CellLine"},{"id":"1601","span":{"begin":1206,"end":1211},"obj":"Mutation"}],"attributes":[{"id":"A1585","pred":"tao:has_database_id","subj":"1585","obj":"Gene:1803"},{"id":"A1586","pred":"tao:has_database_id","subj":"1586","obj":"Gene:1803"},{"id":"A1587","pred":"tao:has_database_id","subj":"1587","obj":"Gene:1803"},{"id":"A1588","pred":"tao:has_database_id","subj":"1588","obj":"Gene:1803"},{"id":"A1589","pred":"tao:has_database_id","subj":"1589","obj":"Tax:1335626"},{"id":"A1590","pred":"tao:has_database_id","subj":"1590","obj":"Tax:9606"},{"id":"A1591","pred":"tao:has_database_id","subj":"1591","obj":"Tax:9838"},{"id":"A1592","pred":"tao:has_database_id","subj":"1592","obj":"Tax:1335626"},{"id":"A1593","pred":"tao:has_database_id","subj":"1593","obj":"Tax:1335626"},{"id":"A1594","pred":"tao:has_database_id","subj":"1594","obj":"Tax:10090"},{"id":"A1595","pred":"tao:has_database_id","subj":"1595","obj":"Tax:10090"},{"id":"A1596","pred":"tao:has_database_id","subj":"1596","obj":"Tax:1335626"},{"id":"A1597","pred":"tao:has_database_id","subj":"1597","obj":"Tax:10090"},{"id":"A1598","pred":"tao:has_database_id","subj":"1598","obj":"MESH:D018352"},{"id":"A1599","pred":"tao:has_database_id","subj":"1599","obj":"MESH:D007154"},{"id":"A1600","pred":"tao:has_database_id","subj":"1600","obj":"CVCL:0213"},{"id":"A1601","pred":"tao:has_standard_notation","subj":"1601","obj":"p.T579N"},{"subj":"1585","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1586","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1587","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1588","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1589","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1590","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1591","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1592","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1593","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1594","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1595","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1596","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1597","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1598","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1599","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1600","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1601","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T288","span":{"begin":179,"end":183},"obj":"Body_part"},{"id":"T289","span":{"begin":435,"end":443},"obj":"Body_part"},{"id":"T290","span":{"begin":805,"end":813},"obj":"Body_part"},{"id":"T291","span":{"begin":1000,"end":1012},"obj":"Body_part"},{"id":"T292","span":{"begin":1158,"end":1165},"obj":"Body_part"}],"attributes":[{"id":"A288","pred":"fma_id","subj":"T288","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A289","pred":"fma_id","subj":"T289","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A290","pred":"fma_id","subj":"T290","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A291","pred":"fma_id","subj":"T291","obj":"http://purl.org/sig/ont/fma/fma62861"},{"id":"A292","pred":"fma_id","subj":"T292","obj":"http://purl.org/sig/ont/fma/fma67257"},{"subj":"T288","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T289","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T290","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T291","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T292","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid_AGAC","denotations":[{"id":"p63240s94","span":{"begin":1230,"end":1242},"obj":"MPA"}],"attributes":[{"subj":"p63240s94","pred":"source","obj":"LitCovid_AGAC"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T256","span":{"begin":245,"end":247},"obj":"Disease"},{"id":"T257","span":{"begin":948,"end":957},"obj":"Disease"}],"attributes":[{"id":"A256","pred":"mondo_id","subj":"T256","obj":"http://purl.obolibrary.org/obo/MONDO_0010526"},{"id":"A257","pred":"mondo_id","subj":"T257","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"subj":"T256","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T257","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T613","span":{"begin":166,"end":167},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T614","span":{"begin":175,"end":183},"obj":"http://purl.obolibrary.org/obo/CLO_0002421"},{"id":"T615","span":{"begin":199,"end":201},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T616","span":{"begin":216,"end":217},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T617","span":{"begin":322,"end":327},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T618","span":{"begin":332,"end":337},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9837"},{"id":"T619","span":{"begin":418,"end":422},"obj":"http://purl.obolibrary.org/obo/CLO_0001185"},{"id":"T620","span":{"begin":754,"end":758},"obj":"http://purl.obolibrary.org/obo/CLO_0001185"},{"id":"T621","span":{"begin":1086,"end":1090},"obj":"http://purl.obolibrary.org/obo/CLO_0001185"},{"id":"T622","span":{"begin":1107,"end":1108},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T623","span":{"begin":1171,"end":1172},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T624","span":{"begin":1291,"end":1299},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"attributes":[{"subj":"T613","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T614","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T615","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T616","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T617","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T618","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T619","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T620","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T621","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T622","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T623","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T624","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T16276","span":{"begin":435,"end":443},"obj":"Chemical"},{"id":"T73097","span":{"begin":805,"end":813},"obj":"Chemical"},{"id":"T35260","span":{"begin":925,"end":927},"obj":"Chemical"},{"id":"T72523","span":{"begin":1158,"end":1165},"obj":"Chemical"},{"id":"T36047","span":{"begin":1190,"end":1197},"obj":"Chemical"},{"id":"T53533","span":{"begin":1367,"end":1369},"obj":"Chemical"}],"attributes":[{"id":"A51367","pred":"chebi_id","subj":"T16276","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A94786","pred":"chebi_id","subj":"T73097","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A93608","pred":"chebi_id","subj":"T35260","obj":"http://purl.obolibrary.org/obo/CHEBI_9516"},{"id":"A62413","pred":"chebi_id","subj":"T72523","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A4692","pred":"chebi_id","subj":"T36047","obj":"http://purl.obolibrary.org/obo/CHEBI_53000"},{"id":"A60282","pred":"chebi_id","subj":"T53533","obj":"http://purl.obolibrary.org/obo/CHEBI_9516"},{"subj":"T16276","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T73097","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T35260","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T72523","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T36047","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T53533","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"2_test","denotations":[{"id":"32265848-27750111-36511211","span":{"begin":393,"end":397},"obj":"27750111"},{"id":"32265848-27795425-36511212","span":{"begin":399,"end":403},"obj":"27795425"},{"id":"32265848-29496347-36511213","span":{"begin":418,"end":422},"obj":"29496347"},{"id":"32265848-27750111-36511214","span":{"begin":729,"end":733},"obj":"27750111"},{"id":"32265848-27795425-36511215","span":{"begin":735,"end":739},"obj":"27795425"},{"id":"32265848-29496347-36511216","span":{"begin":754,"end":758},"obj":"29496347"},{"id":"32265848-27750111-36511217","span":{"begin":1045,"end":1049},"obj":"27750111"},{"id":"32265848-28277821-36511218","span":{"begin":1067,"end":1071},"obj":"28277821"},{"id":"32265848-29496347-36511219","span":{"begin":1086,"end":1090},"obj":"29496347"}],"attributes":[{"subj":"32265848-27750111-36511211","pred":"source","obj":"2_test"},{"subj":"32265848-27795425-36511212","pred":"source","obj":"2_test"},{"subj":"32265848-29496347-36511213","pred":"source","obj":"2_test"},{"subj":"32265848-27750111-36511214","pred":"source","obj":"2_test"},{"subj":"32265848-27795425-36511215","pred":"source","obj":"2_test"},{"subj":"32265848-29496347-36511216","pred":"source","obj":"2_test"},{"subj":"32265848-27750111-36511217","pred":"source","obj":"2_test"},{"subj":"32265848-28277821-36511218","pred":"source","obj":"2_test"},{"subj":"32265848-29496347-36511219","pred":"source","obj":"2_test"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T276","span":{"begin":0,"end":424},"obj":"Sentence"},{"id":"T277","span":{"begin":425,"end":760},"obj":"Sentence"},{"id":"T278","span":{"begin":761,"end":1431},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T276","pred":"source","obj":"LitCovid-sentences"},{"subj":"T277","pred":"source","obj":"LitCovid-sentences"},{"subj":"T278","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T795","span":{"begin":22,"end":30},"obj":"SP_9"},{"id":"T796","span":{"begin":113,"end":119},"obj":"SO:0000417"},{"id":"T797","span":{"begin":153,"end":162},"obj":"GO:0010467"},{"id":"T798","span":{"begin":322,"end":327},"obj":"SP_6;NCBITaxon:9606"},{"id":"T799","span":{"begin":332,"end":337},"obj":"SP_3"},{"id":"T800","span":{"begin":365,"end":369},"obj":"SP_9"},{"id":"T801","span":{"begin":505,"end":519},"obj":"BV_15"},{"id":"T802","span":{"begin":546,"end":550},"obj":"PG_7;PR:000001341"},{"id":"T803","span":{"begin":629,"end":639},"obj":"GO:0042571"},{"id":"T804","span":{"begin":679,"end":683},"obj":"SP_9;NCBITaxon:8088"},{"id":"T805","span":{"begin":684,"end":697},"obj":"NCBITaxon:11886;SO:0000336"},{"id":"T806","span":{"begin":707,"end":715},"obj":"SP_9"},{"id":"T807","span":{"begin":792,"end":800},"obj":"SP_9"},{"id":"T808","span":{"begin":865,"end":871},"obj":"SO:0000417"},{"id":"T809","span":{"begin":901,"end":906},"obj":"PR:P27487"},{"id":"T810","span":{"begin":919,"end":924},"obj":"PR:P27487"},{"id":"T811","span":{"begin":929,"end":933},"obj":"NCBITaxon:10088"},{"id":"T812","span":{"begin":939,"end":947},"obj":"SP_9"},{"id":"T813","span":{"begin":1000,"end":1012},"obj":"CL:0000771"},{"id":"T814","span":{"begin":1013,"end":1019},"obj":"UBERON:0002405"},{"id":"T815","span":{"begin":1190,"end":1197},"obj":"BV_9"},{"id":"T816","span":{"begin":1361,"end":1366},"obj":"PR:P27487"},{"id":"T817","span":{"begin":1370,"end":1374},"obj":"NCBITaxon:10088"},{"id":"T818","span":{"begin":1393,"end":1401},"obj":"SP_9"},{"id":"T55637","span":{"begin":22,"end":30},"obj":"SP_9"},{"id":"T31962","span":{"begin":113,"end":119},"obj":"SO:0000417"},{"id":"T59635","span":{"begin":153,"end":162},"obj":"GO:0010467"},{"id":"T22093","span":{"begin":322,"end":327},"obj":"SP_6;NCBITaxon:9606"},{"id":"T34241","span":{"begin":332,"end":337},"obj":"SP_3"},{"id":"T77529","span":{"begin":365,"end":369},"obj":"SP_9"},{"id":"T89636","span":{"begin":505,"end":519},"obj":"BV_15"},{"id":"T41507","span":{"begin":546,"end":550},"obj":"PG_7;PR:000001341"},{"id":"T90698","span":{"begin":629,"end":639},"obj":"GO:0042571"},{"id":"T29648","span":{"begin":679,"end":683},"obj":"SP_9;NCBITaxon:8088"},{"id":"T89366","span":{"begin":684,"end":697},"obj":"NCBITaxon:11886;SO:0000336"},{"id":"T16249","span":{"begin":707,"end":715},"obj":"SP_9"},{"id":"T28192","span":{"begin":792,"end":800},"obj":"SP_9"},{"id":"T31584","span":{"begin":865,"end":871},"obj":"SO:0000417"},{"id":"T92178","span":{"begin":901,"end":906},"obj":"PR:P27487"},{"id":"T38972","span":{"begin":919,"end":924},"obj":"PR:P27487"},{"id":"T61802","span":{"begin":929,"end":933},"obj":"NCBITaxon:10088"},{"id":"T74601","span":{"begin":939,"end":947},"obj":"SP_9"},{"id":"T45545","span":{"begin":1000,"end":1012},"obj":"CL:0000771"},{"id":"T94648","span":{"begin":1013,"end":1019},"obj":"UBERON:0002405"},{"id":"T24627","span":{"begin":1190,"end":1197},"obj":"BV_9"},{"id":"T39464","span":{"begin":1361,"end":1366},"obj":"PR:P27487"},{"id":"T43750","span":{"begin":1370,"end":1374},"obj":"NCBITaxon:10088"},{"id":"T72839","span":{"begin":1393,"end":1401},"obj":"SP_9"}],"attributes":[{"subj":"T795","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T796","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T797","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T798","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T799","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T800","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T801","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T802","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T803","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T804","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T805","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T806","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T807","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T808","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T809","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T810","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T811","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T812","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T813","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T814","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T815","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T816","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T817","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T818","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T55637","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T31962","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T59635","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T22093","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T34241","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T77529","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T89636","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T41507","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T90698","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T29648","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T89366","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T16249","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T28192","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T31584","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T92178","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T38972","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T61802","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T74601","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T45545","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T94648","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T24627","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T39464","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T43750","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T72839","pred":"source","obj":"LitCovid-PMC-OGER-BB"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#93c5ec","default":true},{"id":"LitCovid-PD-FMA-UBERON","color":"#dfec93"},{"id":"LitCovid_AGAC","color":"#df93ec"},{"id":"LitCovid-PD-MONDO","color":"#93ecc5"},{"id":"LitCovid-PD-CLO","color":"#ecab93"},{"id":"LitCovid-PD-CHEBI","color":"#9394ec"},{"id":"2_test","color":"#aeec93"},{"id":"LitCovid-sentences","color":"#ec93c8"},{"id":"LitCovid-PMC-OGER-BB","color":"#93e2ec"}]}]}}