PMC:7105881 / 49474-49822 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"1552","span":{"begin":161,"end":165},"obj":"Gene"},{"id":"1561","span":{"begin":45,"end":53},"obj":"Species"},{"id":"1562","span":{"begin":264,"end":272},"obj":"Species"}],"attributes":[{"id":"A1552","pred":"tao:has_database_id","subj":"1552","obj":"Gene:1803"},{"id":"A1561","pred":"tao:has_database_id","subj":"1561","obj":"Tax:1335626"},{"id":"A1562","pred":"tao:has_database_id","subj":"1562","obj":"Tax:1335626"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"However, after comparing several versions of MERS-CoV RBD fragments with different lengths, it was found that a truncated RBD (residues 377–588) had the highest DPP4-binding affinity and induced the highest-titer IgG antibodies and neutralizing antibodies against MERS-CoV, identifying its role as a critical neutralizing domain (Ma et al., 2014b)."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T287","span":{"begin":213,"end":216},"obj":"Body_part"}],"attributes":[{"id":"A287","pred":"fma_id","subj":"T287","obj":"http://purl.org/sig/ont/fma/fma62872"}],"text":"However, after comparing several versions of MERS-CoV RBD fragments with different lengths, it was found that a truncated RBD (residues 377–588) had the highest DPP4-binding affinity and induced the highest-titer IgG antibodies and neutralizing antibodies against MERS-CoV, identifying its role as a critical neutralizing domain (Ma et al., 2014b)."}

{"project":"LitCovid_AGAC","denotations":[{"id":"p63237s40","span":{"begin":206,"end":227},"obj":"MPA"},{"id":"p63237s45","span":{"begin":232,"end":244},"obj":"NegReg"}],"text":"However, after comparing several versions of MERS-CoV RBD fragments with different lengths, it was found that a truncated RBD (residues 377–588) had the highest DPP4-binding affinity and induced the highest-titer IgG antibodies and neutralizing antibodies against MERS-CoV, identifying its role as a critical neutralizing domain (Ma et al., 2014b)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T611","span":{"begin":110,"end":111},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T612","span":{"begin":298,"end":299},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"However, after comparing several versions of MERS-CoV RBD fragments with different lengths, it was found that a truncated RBD (residues 377–588) had the highest DPP4-binding affinity and induced the highest-titer IgG antibodies and neutralizing antibodies against MERS-CoV, identifying its role as a critical neutralizing domain (Ma et al., 2014b)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T275","span":{"begin":0,"end":348},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"However, after comparing several versions of MERS-CoV RBD fragments with different lengths, it was found that a truncated RBD (residues 377–588) had the highest DPP4-binding affinity and induced the highest-titer IgG antibodies and neutralizing antibodies against MERS-CoV, identifying its role as a critical neutralizing domain (Ma et al., 2014b)."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T789","span":{"begin":45,"end":53},"obj":"SP_9"},{"id":"T790","span":{"begin":161,"end":165},"obj":"PG_7;PR:000001341"},{"id":"T791","span":{"begin":213,"end":227},"obj":"GO:0071743"},{"id":"T792","span":{"begin":245,"end":255},"obj":"GO:0042571"},{"id":"T793","span":{"begin":264,"end":272},"obj":"SP_9"},{"id":"T794","span":{"begin":322,"end":328},"obj":"SO:0000417"},{"id":"T4889","span":{"begin":45,"end":53},"obj":"SP_9"},{"id":"T42008","span":{"begin":161,"end":165},"obj":"PG_7;PR:000001341"},{"id":"T18053","span":{"begin":213,"end":227},"obj":"GO:0071743"},{"id":"T36846","span":{"begin":245,"end":255},"obj":"GO:0042571"},{"id":"T37521","span":{"begin":264,"end":272},"obj":"SP_9"},{"id":"T31324","span":{"begin":322,"end":328},"obj":"SO:0000417"}],"text":"However, after comparing several versions of MERS-CoV RBD fragments with different lengths, it was found that a truncated RBD (residues 377–588) had the highest DPP4-binding affinity and induced the highest-titer IgG antibodies and neutralizing antibodies against MERS-CoV, identifying its role as a critical neutralizing domain (Ma et al., 2014b)."}