PMC:7105881 / 42220-42596 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"1373","span":{"begin":36,"end":40},"obj":"Gene"},{"id":"1374","span":{"begin":163,"end":167},"obj":"Gene"},{"id":"1375","span":{"begin":169,"end":174},"obj":"Gene"},{"id":"1376","span":{"begin":180,"end":184},"obj":"Gene"},{"id":"1377","span":{"begin":312,"end":317},"obj":"Gene"},{"id":"1378","span":{"begin":322,"end":326},"obj":"Gene"},{"id":"1412","span":{"begin":138,"end":141},"obj":"Gene"},{"id":"1429","span":{"begin":94,"end":98},"obj":"Species"},{"id":"1430","span":{"begin":108,"end":116},"obj":"Species"},{"id":"1431","span":{"begin":189,"end":193},"obj":"Species"},{"id":"1432","span":{"begin":229,"end":237},"obj":"Species"},{"id":"1433","span":{"begin":264,"end":272},"obj":"Species"},{"id":"1434","span":{"begin":331,"end":335},"obj":"Species"}],"attributes":[{"id":"A1373","pred":"tao:has_database_id","subj":"1373","obj":"Gene:1803"},{"id":"A1374","pred":"tao:has_database_id","subj":"1374","obj":"Gene:16017"},{"id":"A1375","pred":"tao:has_database_id","subj":"1375","obj":"Gene:668478"},{"id":"A1376","pred":"tao:has_database_id","subj":"1376","obj":"Gene:3502"},{"id":"A1377","pred":"tao:has_database_id","subj":"1377","obj":"Gene:3458"},{"id":"A1378","pred":"tao:has_database_id","subj":"1378","obj":"Gene:3558"},{"id":"A1412","pred":"tao:has_database_id","subj":"1412","obj":"Gene:51428"},{"id":"A1429","pred":"tao:has_database_id","subj":"1429","obj":"Tax:10090"},{"id":"A1430","pred":"tao:has_database_id","subj":"1430","obj":"Tax:1335626"},{"id":"A1431","pred":"tao:has_database_id","subj":"1431","obj":"Tax:10090"},{"id":"A1432","pred":"tao:has_database_id","subj":"1432","obj":"Tax:1335626"},{"id":"A1433","pred":"tao:has_database_id","subj":"1433","obj":"Tax:1335626"},{"id":"A1434","pred":"tao:has_database_id","subj":"1434","obj":"Tax:10090"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"RBD (S377-662)-Fc protein Binds to DPP4 receptor Poly(I:C); Montanide I.N. or S.C. BALB/c mice Elicits MERS-CoV S1- and RBD-specific Abs (IgA, IgG (\u003e 1:104), IgG1, IgG2a, and IgG3) in mice, neutralizing (≥ 1:2.4 × 102) live MERS-CoV (EMC2012 strain) Induces MERS-CoV S1-specific cellular immune responses (IFN-γ and IL-2) in mice N/A Du et al., 2013c; Ma et al., 2014b"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T252","span":{"begin":18,"end":25},"obj":"Body_part"},{"id":"T253","span":{"begin":143,"end":146},"obj":"Body_part"},{"id":"T254","span":{"begin":148,"end":151},"obj":"Body_part"},{"id":"T255","span":{"begin":322,"end":326},"obj":"Body_part"}],"attributes":[{"id":"A252","pred":"fma_id","subj":"T252","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A253","pred":"fma_id","subj":"T253","obj":"http://purl.org/sig/ont/fma/fma62874"},{"id":"A254","pred":"fma_id","subj":"T254","obj":"http://purl.org/sig/ont/fma/fma62872"},{"id":"A255","pred":"fma_id","subj":"T255","obj":"http://purl.org/sig/ont/fma/fma84051"}],"text":"RBD (S377-662)-Fc protein Binds to DPP4 receptor Poly(I:C); Montanide I.N. or S.C. BALB/c mice Elicits MERS-CoV S1- and RBD-specific Abs (IgA, IgG (\u003e 1:104), IgG1, IgG2a, and IgG3) in mice, neutralizing (≥ 1:2.4 × 102) live MERS-CoV (EMC2012 strain) Induces MERS-CoV S1-specific cellular immune responses (IFN-γ and IL-2) in mice N/A Du et al., 2013c; Ma et al., 2014b"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T546","span":{"begin":15,"end":17},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T547","span":{"begin":117,"end":119},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T548","span":{"begin":219,"end":222},"obj":"http://purl.obolibrary.org/obo/CLO_0054060"},{"id":"T549","span":{"begin":273,"end":275},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T550","span":{"begin":322,"end":326},"obj":"http://purl.obolibrary.org/obo/PR_000001379"},{"id":"T551","span":{"begin":339,"end":340},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"RBD (S377-662)-Fc protein Binds to DPP4 receptor Poly(I:C); Montanide I.N. or S.C. BALB/c mice Elicits MERS-CoV S1- and RBD-specific Abs (IgA, IgG (\u003e 1:104), IgG1, IgG2a, and IgG3) in mice, neutralizing (≥ 1:2.4 × 102) live MERS-CoV (EMC2012 strain) Induces MERS-CoV S1-specific cellular immune responses (IFN-γ and IL-2) in mice N/A Du et al., 2013c; Ma et al., 2014b"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T276","span":{"begin":18,"end":25},"obj":"Chemical"},{"id":"T277","span":{"begin":322,"end":324},"obj":"Chemical"}],"attributes":[{"id":"A276","pred":"chebi_id","subj":"T276","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A277","pred":"chebi_id","subj":"T277","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A278","pred":"chebi_id","subj":"T277","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"}],"text":"RBD (S377-662)-Fc protein Binds to DPP4 receptor Poly(I:C); Montanide I.N. or S.C. BALB/c mice Elicits MERS-CoV S1- and RBD-specific Abs (IgA, IgG (\u003e 1:104), IgG1, IgG2a, and IgG3) in mice, neutralizing (≥ 1:2.4 × 102) live MERS-CoV (EMC2012 strain) Induces MERS-CoV S1-specific cellular immune responses (IFN-γ and IL-2) in mice N/A Du et al., 2013c; Ma et al., 2014b"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T84","span":{"begin":285,"end":310},"obj":"http://purl.obolibrary.org/obo/GO_0002456"},{"id":"T85","span":{"begin":285,"end":310},"obj":"http://purl.obolibrary.org/obo/GO_0002449"},{"id":"T86","span":{"begin":285,"end":310},"obj":"http://purl.obolibrary.org/obo/GO_0002443"}],"text":"RBD (S377-662)-Fc protein Binds to DPP4 receptor Poly(I:C); Montanide I.N. or S.C. BALB/c mice Elicits MERS-CoV S1- and RBD-specific Abs (IgA, IgG (\u003e 1:104), IgG1, IgG2a, and IgG3) in mice, neutralizing (≥ 1:2.4 × 102) live MERS-CoV (EMC2012 strain) Induces MERS-CoV S1-specific cellular immune responses (IFN-γ and IL-2) in mice N/A Du et al., 2013c; Ma et al., 2014b"}

{"project":"LitCovid-sentences","denotations":[{"id":"T243","span":{"begin":0,"end":85},"obj":"Sentence"},{"id":"T244","span":{"begin":87,"end":376},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"RBD (S377-662)-Fc protein Binds to DPP4 receptor Poly(I:C); Montanide I.N. or S.C. BALB/c mice Elicits MERS-CoV S1- and RBD-specific Abs (IgA, IgG (\u003e 1:104), IgG1, IgG2a, and IgG3) in mice, neutralizing (≥ 1:2.4 × 102) live MERS-CoV (EMC2012 strain) Induces MERS-CoV S1-specific cellular immune responses (IFN-γ and IL-2) in mice N/A Du et al., 2013c; Ma et al., 2014b"}