PMC:7105881 / 41096-45789
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id | tao:has_standard_notation |
|---|---|---|---|---|---|---|
| 1363 | 232-236 | Gene | denotes | DPP4 | Gene:1803 | |
| 1364 | 686-690 | Gene | denotes | IgG1 | Gene:16017 | |
| 1365 | 692-697 | Gene | denotes | IgG2a | Gene:668478 | |
| 1366 | 703-708 | Gene | denotes | IgG2b | Gene:16016 | |
| 1367 | 885-890 | Gene | denotes | IFN-γ | Gene:3458 | |
| 1368 | 892-897 | Gene | denotes | TNF-α | Gene:7124 | |
| 1369 | 899-903 | Gene | denotes | IL-2 | Gene:3558 | |
| 1370 | 905-909 | Gene | denotes | IL-4 | Gene:3565 | |
| 1371 | 911-915 | Gene | denotes | IL-6 | Gene:3569 | |
| 1372 | 921-926 | Gene | denotes | IL-10 | Gene:3586 | |
| 1373 | 1160-1164 | Gene | denotes | DPP4 | Gene:1803 | |
| 1374 | 1287-1291 | Gene | denotes | IgG1 | Gene:16017 | |
| 1375 | 1293-1298 | Gene | denotes | IgG2a | Gene:668478 | |
| 1376 | 1304-1308 | Gene | denotes | IgG3 | Gene:3502 | |
| 1377 | 1436-1441 | Gene | denotes | IFN-γ | Gene:3458 | |
| 1378 | 1446-1450 | Gene | denotes | IL-2 | Gene:3558 | |
| 1379 | 1537-1541 | Gene | denotes | DPP4 | Gene:13482 | |
| 1380 | 1682-1687 | Gene | denotes | hDPP4 | Gene:1803 | |
| 1381 | 1771-1775 | Gene | denotes | IgG1 | Gene:16017 | |
| 1382 | 1781-1786 | Gene | denotes | IgG2a | Gene:668478 | |
| 1383 | 1967-1972 | Gene | denotes | IFN-γ | Gene:3458 | |
| 1384 | 1977-1981 | Gene | denotes | IL-2 | Gene:3558 | |
| 1385 | 2016-2021 | Gene | denotes | hDPP4 | Gene:1803 | |
| 1386 | 2078-2083 | Gene | denotes | hDPP4 | Gene:1803 | |
| 1387 | 2360-2364 | Gene | denotes | DPP4 | Gene:1803 | |
| 1388 | 2491-2496 | Gene | denotes | hDPP4 | Gene:1803 | |
| 1389 | 2555-2559 | Gene | denotes | IgG1 | Gene:16017 | |
| 1390 | 2565-2570 | Gene | denotes | IgG2a | Gene:668478 | |
| 1391 | 2716-2721 | Gene | denotes | hDPP4 | Gene:1803 | |
| 1392 | 2843-2847 | Gene | denotes | DPP4 | Gene:1803 | |
| 1393 | 2967-2972 | Gene | denotes | hDPP4 | Gene:1803 | |
| 1394 | 3098-3103 | Gene | denotes | hDPP4 | Gene:1803 | |
| 1395 | 3357-3361 | Gene | denotes | IgG1 | Gene:16017 | |
| 1396 | 3567-3591 | Gene | denotes | CT Wang et al., 2015 S1 | Gene:7276 | |
| 1397 | 4071-4076 | Gene | denotes | hDPP4 | Gene:1803 | |
| 1398 | 4115-4118 | Gene | denotes | Abs | Gene:51428 | |
| 1399 | 4270-4275 | Gene | denotes | IFN-γ | Gene:3458 | |
| 1400 | 4277-4281 | Gene | denotes | IL-2 | Gene:3558 | |
| 1401 | 4283-4287 | Gene | denotes | IL-6 | Gene:3569 | |
| 1402 | 4289-4294 | Gene | denotes | IL-10 | Gene:3586 | |
| 1403 | 4300-4306 | Gene | denotes | IL-17A | Gene:3605 | |
| 1404 | 4502-4505 | Gene | denotes | SP3 | Gene:6670 | |
| 1405 | 4341-4346 | Gene | denotes | hDPP4 | Gene:1803 | |
| 1406 | 4601-4604 | Gene | denotes | Abs | Gene:51428 | |
| 1407 | 3673-3676 | Gene | denotes | Abs | Gene:72935 | |
| 1408 | 3336-3339 | Gene | denotes | Abs | Gene:51428 | |
| 1409 | 3003-3006 | Gene | denotes | Abs | Gene:72935 | |
| 1410 | 2535-2538 | Gene | denotes | Abs | Gene:51428 | |
| 1411 | 1743-1746 | Gene | denotes | Abs | Gene:51428 | |
| 1412 | 1262-1265 | Gene | denotes | Abs | Gene:51428 | |
| 1413 | 668-671 | Gene | denotes | Abs | Gene:51428 | |
| 1414 | 383-386 | Gene | denotes | Abs | Gene:72935 | |
| 1415 | 173-181 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1416 | 250-258 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1417 | 356-360 | Species | denotes | mice | Tax:10090 | |
| 1418 | 390-394 | Species | denotes | mice | Tax:10090 | |
| 1419 | 423-431 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1420 | 491-499 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1421 | 584-589 | Species | denotes | mouse | Tax:10090 | |
| 1422 | 626-630 | Species | denotes | mice | Tax:10090 | |
| 1423 | 646-654 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1424 | 752-757 | Species | denotes | mouse | Tax:10090 | |
| 1425 | 801-809 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1426 | 836-844 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1427 | 931-935 | Species | denotes | mice | Tax:10090 | |
| 1428 | 1005-1013 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1429 | 1218-1222 | Species | denotes | mice | Tax:10090 | |
| 1430 | 1232-1240 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1431 | 1313-1317 | Species | denotes | mice | Tax:10090 | |
| 1432 | 1353-1361 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1433 | 1388-1396 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1434 | 1455-1459 | Species | denotes | mice | Tax:10090 | |
| 1435 | 1555-1563 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1436 | 1676-1680 | Species | denotes | mice | Tax:10090 | |
| 1437 | 1691-1695 | Species | denotes | mice | Tax:10090 | |
| 1438 | 1697-1704 | Species | denotes | Rabbits | Tax:9986 | |
| 1439 | 1714-1722 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1440 | 1866-1874 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1441 | 1919-1927 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1442 | 1986-1990 | Species | denotes | mice | Tax:10090 | |
| 1443 | 2040-2044 | Species | denotes | mice | Tax:10090 | |
| 1444 | 2087-2091 | Species | denotes | mice | Tax:10090 | |
| 1445 | 2097-2105 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1446 | 2378-2386 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1447 | 2485-2489 | Species | denotes | mice | Tax:10090 | |
| 1448 | 2500-2504 | Species | denotes | mice | Tax:10090 | |
| 1449 | 2514-2522 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1450 | 2575-2579 | Species | denotes | mice | Tax:10090 | |
| 1451 | 2646-2654 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1452 | 2725-2729 | Species | denotes | mice | Tax:10090 | |
| 1453 | 2748-2756 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1454 | 2852-2860 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1455 | 2961-2965 | Species | denotes | mice | Tax:10090 | |
| 1456 | 2976-2980 | Species | denotes | mice | Tax:10090 | |
| 1457 | 3024-3028 | Species | denotes | mice | Tax:10090 | |
| 1458 | 3042-3050 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1459 | 3107-3111 | Species | denotes | mice | Tax:10090 | |
| 1460 | 3130-3138 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1461 | 3220-3228 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1462 | 3295-3299 | Species | denotes | mice | Tax:10090 | |
| 1463 | 3315-3323 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1464 | 3415-3423 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1465 | 3491-3499 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1466 | 3625-3634 | Species | denotes | Dromedary | Tax:9838 | |
| 1467 | 3635-3641 | Species | denotes | camels | Tax:9838 | |
| 1468 | 3643-3650 | Species | denotes | Alpacas | Tax:30538 | |
| 1469 | 3680-3689 | Species | denotes | dromedary | Tax:9838 | |
| 1470 | 3690-3696 | Species | denotes | camels | Tax:9838 | |
| 1471 | 3710-3717 | Species | denotes | alpacas | Tax:30538 | |
| 1472 | 3747-3755 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1473 | 3799-3808 | Species | denotes | dromedary | Tax:9838 | |
| 1474 | 3809-3815 | Species | denotes | camels | Tax:9838 | |
| 1475 | 3820-3827 | Species | denotes | alpacas | Tax:30538 | |
| 1476 | 3846-3854 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1477 | 3949-3955 | Species | denotes | camels | Tax:9838 | |
| 1478 | 3984-3991 | Species | denotes | alpacas | Tax:30538 | |
| 1479 | 4061-4065 | Species | denotes | mice | Tax:10090 | |
| 1480 | 4077-4081 | Species | denotes | mice | Tax:10090 | |
| 1481 | 4091-4099 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1482 | 4137-4141 | Species | denotes | mice | Tax:10090 | |
| 1483 | 4184-4192 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1484 | 4219-4227 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1485 | 4311-4315 | Species | denotes | mice | Tax:10090 | |
| 1486 | 4358-4362 | Species | denotes | mice | Tax:10090 | |
| 1487 | 4381-4389 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1488 | 4554-4558 | Species | denotes | mice | Tax:10090 | |
| 1489 | 4564-4571 | Species | denotes | rabbits | Tax:9986 | |
| 1490 | 4581-4589 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1491 | 4621-4628 | Species | denotes | rabbits | Tax:9986 | |
| 1492 | 4655-4663 | Species | denotes | MERS-CoV | Tax:1335626 | |
| 1493 | 675-679 | Species | denotes | mice | Tax:10090 | |
| 1494 | 1750-1754 | Species | denotes | mice | Tax:10090 | |
| 1495 | 1792-1799 | Species | denotes | rabbits | Tax:9986 | |
| 1496 | 3343-3347 | Species | denotes | mice | Tax:10090 | |
| 1497 | 1065-1074 | Disease | denotes | pneumonia | MESH:D011014 | |
| 1498 | 2183-2205 | Disease | denotes | immunological toxicity | MESH:D007154 | |
| 1499 | 3536-3557 | Disease | denotes | reduced abnormalities | MESH:D015354 | |
| 1500 | 4429-4447 | Disease | denotes | lung abnormalities | MESH:D008171 | |
| 1501 | 2809-2814 | Mutation | denotes | T579N | p.T579N |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T244 | 70-78 | Body_part | denotes | Antibody | http://purl.org/sig/ont/fma/fma62871 |
| T245 | 196-203 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T246 | 214-221 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T247 | 504-511 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T248 | 528-535 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T249 | 681-684 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T250 | 720-723 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T251 | 899-903 | Body_part | denotes | IL-2 | http://purl.org/sig/ont/fma/fma84051 |
| T252 | 1142-1149 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T253 | 1267-1270 | Body_part | denotes | IgA | http://purl.org/sig/ont/fma/fma62874 |
| T254 | 1272-1275 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T255 | 1446-1450 | Body_part | denotes | IL-2 | http://purl.org/sig/ont/fma/fma84051 |
| T256 | 1519-1526 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T257 | 1756-1759 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T258 | 1801-1804 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T259 | 1977-1981 | Body_part | denotes | IL-2 | http://purl.org/sig/ont/fma/fma84051 |
| T260 | 2209-2221 | Body_part | denotes | eosinophilic | http://purl.org/sig/ont/fma/fma62861 |
| T261 | 2342-2349 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T262 | 2540-2543 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T263 | 2816-2823 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T264 | 3231-3238 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T265 | 3252-3259 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T266 | 3349-3352 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T267 | 3373-3376 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T268 | 3561-3566 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
| T269 | 3592-3599 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T270 | 4018-4025 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T271 | 4120-4123 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T272 | 4277-4281 | Body_part | denotes | IL-2 | http://purl.org/sig/ont/fma/fma84051 |
| T273 | 4429-4433 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T274 | 4452-4469 | Body_part | denotes | respiratory tract | http://purl.org/sig/ont/fma/fma265130 |
| T275 | 4606-4609 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T14 | 3561-3566 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T15 | 4429-4433 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T16 | 4452-4469 | Body_part | denotes | respiratory tract | http://purl.obolibrary.org/obo/UBERON_0000065 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T232 | 261-264 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
| T234 | 1065-1074 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T235 | 2012-2015 | Disease | denotes | Ad5 | http://purl.obolibrary.org/obo/MONDO_0011194 |
| T236 | 2339-2341 | Disease | denotes | Fd | http://purl.obolibrary.org/obo/MONDO_0010526 |
| T237 | 4067-4070 | Disease | denotes | Ad5 | http://purl.obolibrary.org/obo/MONDO_0011194 |
| T238 | 4102-4105 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
| T240 | 4230-4233 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
| T242 | 4337-4340 | Disease | denotes | Ad5 | http://purl.obolibrary.org/obo/MONDO_0011194 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T532 | 55-61 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | Animal |
| T533 | 275-277 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T534 | 275-277 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T535 | 306-308 | http://purl.obolibrary.org/obo/CLO_0003414 | denotes | G2 |
| T536 | 338-341 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAS |
| T537 | 435-436 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T538 | 440-441 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T539 | 539-540 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T540 | 584-589 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
| T541 | 752-757 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
| T542 | 767-770 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
| T543 | 796-799 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
| T544 | 899-903 | http://purl.obolibrary.org/obo/PR_000001379 | denotes | IL-2 |
| T545 | 943-950 | http://purl.obolibrary.org/obo/NCBITaxon_9479 | denotes | monkeys |
| T546 | 1139-1141 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
| T547 | 1241-1243 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T548 | 1343-1346 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
| T549 | 1397-1399 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T550 | 1446-1450 | http://purl.obolibrary.org/obo/PR_000001379 | denotes | IL-2 |
| T551 | 1463-1464 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T552 | 1516-1518 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
| T553 | 1723-1725 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T554 | 1763-1768 | http://purl.obolibrary.org/obo/CLO_0001040 | denotes | 1:105 |
| T555 | 1928-1930 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T556 | 1977-1981 | http://purl.obolibrary.org/obo/PR_000001379 | denotes | IL-2 |
| T557 | 2330-2334 | http://purl.obolibrary.org/obo/CLO_0001185 | denotes | 2018 |
| T558 | 2523-2525 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T559 | 2547-2552 | http://purl.obolibrary.org/obo/CLO_0001040 | denotes | 1:105 |
| T560 | 2675-2676 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T561 | 3071-3072 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T562 | 3249-3251 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T563 | 3263-3264 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T564 | 3324-3326 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T565 | 3445-3446 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T566 | 3561-3566 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
| T567 | 3589-3591 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T568 | 3603-3604 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T569 | 3614-3617 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAS |
| T570 | 3635-3641 | http://purl.obolibrary.org/obo/NCBITaxon_9837 | denotes | camels |
| T571 | 3690-3696 | http://purl.obolibrary.org/obo/NCBITaxon_9837 | denotes | camels |
| T572 | 3729-3732 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
| T573 | 3776-3777 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T574 | 3809-3815 | http://purl.obolibrary.org/obo/NCBITaxon_9837 | denotes | camels |
| T575 | 3937-3944 | http://purl.obolibrary.org/obo/UBERON_0001005 | denotes | airways |
| T576 | 3949-3955 | http://purl.obolibrary.org/obo/NCBITaxon_9837 | denotes | camels |
| T577 | 4029-4030 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T578 | 4277-4281 | http://purl.obolibrary.org/obo/PR_000001379 | denotes | IL-2 |
| T579 | 4429-4433 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T580 | 4429-4433 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T581 | 4506-4513 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T582 | 4529-4530 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T583 | 4544-4545 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T584 | 4667-4668 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T585 | 4672-4673 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T261 | 196-203 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T262 | 214-221 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T263 | 275-277 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T264 | 319-321 | Chemical | denotes | G4 | http://purl.obolibrary.org/obo/CHEBI_50653 |
| T265 | 504-511 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T266 | 528-535 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T267 | 562-571 | Chemical | denotes | poly(I:C) | http://purl.obolibrary.org/obo/CHEBI_84491 |
| T268 | 899-901 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T270 | 905-907 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T272 | 911-913 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T274 | 921-923 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T276 | 1142-1149 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T277 | 1446-1448 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T279 | 1519-1526 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T280 | 1688-1690 | Chemical | denotes | Tg | http://purl.obolibrary.org/obo/CHEBI_9516 |
| T281 | 1977-1979 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T283 | 2084-2086 | Chemical | denotes | Tg | http://purl.obolibrary.org/obo/CHEBI_9516 |
| T284 | 2160-2162 | Chemical | denotes | Tg | http://purl.obolibrary.org/obo/CHEBI_9516 |
| T285 | 2342-2349 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T286 | 2497-2499 | Chemical | denotes | Tg | http://purl.obolibrary.org/obo/CHEBI_9516 |
| T287 | 2722-2724 | Chemical | denotes | Tg | http://purl.obolibrary.org/obo/CHEBI_9516 |
| T288 | 2816-2823 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T289 | 2973-2975 | Chemical | denotes | Tg | http://purl.obolibrary.org/obo/CHEBI_9516 |
| T290 | 3104-3106 | Chemical | denotes | Tg | http://purl.obolibrary.org/obo/CHEBI_9516 |
| T291 | 3231-3238 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T292 | 3252-3259 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T293 | 3592-3599 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T294 | 4018-4025 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T295 | 4277-4279 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T297 | 4283-4285 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T299 | 4289-4291 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T301 | 4300-4302 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T303 | 4506-4513 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T12 | 1065-1074 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T77 | 89-113 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | Cellular immune response |
| T78 | 89-113 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | Cellular immune response |
| T79 | 89-113 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | Cellular immune response |
| T80 | 98-113 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
| T81 | 858-883 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | cellular immune responses |
| T82 | 858-883 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | cellular immune responses |
| T83 | 858-883 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | cellular immune responses |
| T84 | 1409-1434 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | cellular immune responses |
| T85 | 1409-1434 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | cellular immune responses |
| T86 | 1409-1434 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | cellular immune responses |
| T87 | 1940-1965 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | cellular immune responses |
| T88 | 1940-1965 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | cellular immune responses |
| T89 | 1940-1965 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | cellular immune responses |
| T90 | 3909-3923 | http://purl.obolibrary.org/obo/GO_0019076 | denotes | viral shedding |
| T91 | 4243-4268 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | cellular immune responses |
| T92 | 4243-4268 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | cellular immune responses |
| T93 | 4243-4268 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | cellular immune responses |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32265848-28807998-36511173 | 460-464 | 28807998 | denotes | 2017 |
| 32265848-25405618-36511174 | 1113-1117 | 25405618 | denotes | 2014 |
| 32265848-26629538-36511175 | 1119-1123 | 26629538 | denotes | 2015 |
| 32265848-25874632-36511180 | 2291-2295 | 25874632 | denotes | 2015 |
| 32265848-25640653-36511181 | 2311-2315 | 25640653 | denotes | 2016 |
| 32265848-29496347-36511182 | 2330-2334 | 29496347 | denotes | 2018 |
| 32265848-27750111-36511183 | 2799-2803 | 27750111 | denotes | 2016 |
| 32265848-26218507-36511185 | 3584-3588 | 26218507 | denotes | 2015 |
| 32265848-30832356-36511186 | 4008-4012 | 30832356 | denotes | 2019 |
| 32265848-27899228-36511187 | 4497-4501 | 27899228 | denotes | 2017 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T236 | 0-146 | Sentence | denotes | Name Functionality and antigenicity Adjuvant Route Animal models Antibody response Cellular immune response Protective efficacy References |
| T237 | 147-203 | Sentence | denotes | Subunit vaccines based on MERS-CoV full-length S protein |
| T238 | 204-347 | Sentence | denotes | MERS S-2P protein Binds to DPP4 receptor and MERS-CoV S-NTD, RBD, and S2-specific neutralizing mAbs (G2, D12, and G4, respectively) SAS I.M. |
| T239 | 349-464 | Sentence | denotes | BALB/c mice Elicits neutralizing Abs in mice, neutralizing 7 pseudotyped MERS-CoV N/A N/A Pallesen et al., 2017 |
| T240 | 465-511 | Sentence | denotes | Subunit vaccines based on MERS-CoV RBD protein |
| T241 | 512-617 | Sentence | denotes | rRBD (S367-606) protein N/A Alum Hydro + CpG or poly(I:C); IFA + CpG (mouse); Alum (NHPs) I.M. or S.C. |
| T242 | 619-1123 | Sentence | denotes | BALB/c mice; NHPs Elicits MERS-CoV RBD-specific Abs in mice (IgG, IgG1, IgG2a, and IgG2b) and NHPs (IgG), neutralizing pseudotyped (mouse: < 1:5 × 102) and live (NHPs: < 1:5 × 102) MERS-CoV (EMC2012 strain) Induces MERS-CoV RBD-specific cellular immune responses (IFN-γ, TNF-α, IL-2, IL-4, IL-6, and IL-10) in mice and/or monkeys Partially protects vaccinated NHPs from challenge of MERS-CoV (EMC2012 strain, 6.5 × 107 TCID50) with alleviated pneumonia and decreased viral load Lan et al., 2014, 2015 |
| T243 | 1124-1209 | Sentence | denotes | RBD (S377-662)-Fc protein Binds to DPP4 receptor Poly(I:C); Montanide I.N. or S.C. |
| T244 | 1211-1500 | Sentence | denotes | BALB/c mice Elicits MERS-CoV S1- and RBD-specific Abs (IgA, IgG (> 1:104), IgG1, IgG2a, and IgG3) in mice, neutralizing (≥ 1:2.4 × 102) live MERS-CoV (EMC2012 strain) Induces MERS-CoV S1-specific cellular immune responses (IFN-γ and IL-2) in mice N/A Du et al., 2013c; Ma et al., 2014b |
| T245 | 1501-1667 | Sentence | denotes | RBD (S377-588)-Fc protein Binds to DPP4 receptor and MERS-CoV RBD specific neutralizing mAbs (Mersmab1, m336, m337, and m338) Montanide; MF59; AddaVax I.M. or S.C. |
| T246 | 1669-2334 | Sentence | denotes | BALB/c mice; hDPP4-Tg mice; Rabbits Elicits MERS-CoV S1 and RBD-specific Abs in mice (IgG (> 1:105), IgG1, and IgG2a) and rabbits (IgG), neutralizing 17 pseudotyped (≥ 1:104) and 2 live (≥ 1:103) MERS-CoV (EMC2012 and London1-2012 strains) Induces MERS-CoV S1-specific cellular immune responses (IFN-γ and IL-2) in mice Protects vaccinated Ad5/hDPP4-transduced BALB/c mice and majority (4/6) of vaccinated hDPP4-Tg mice from MERS-CoV (EMC2012 strain, 105 PFU for BALB/c; 103–4 TCID50 for Tg) challenge, without immunological toxicity or eosinophilic immune enhancement Du et al., 2013a; Ma et al., 2014b; Tang et al., 2015; Zhang et al., 2016; Nyon et al., 2018 |
| T247 | 2335-2476 | Sentence | denotes | RBD-Fd protein Binds to DPP4 receptor and MERS-CoV RBD-specific neutralizing mAbs (Mersmab1, m336, m337, and m338) MF59; Alum I.M. or S.C. |
| T248 | 2478-2803 | Sentence | denotes | BALB/c mice; hDPP4-Tg mice Elicits MERS-CoV S1-specific Abs (IgG (> 1:105), IgG1, and IgG2a) in mice, neutralizing at least 9 pseudotyped (> 1:104) and live (> 1:103) MERS-CoV (EMC2012 strain) N/A Protects majority (5/6) of vaccinated hDPP4-Tg mice from challenge of MERS-CoV (EMC2012 strain, 104 TCID50) Tai et al., 2016 |
| T249 | 2804-2952 | Sentence | denotes | RBD (T579N) protein Binds to receptor DPP4 and MERS-CoV RBD-specific neutralizing mAbs (hMS-1, m336, m337, and m338) Montanide; Alum I.M. or S.C. |
| T250 | 2954-3185 | Sentence | denotes | BALB/c mice; hDPP4-Tg mice Elicits neutralizing Abs (> 1:3 × 103) in mice against live MERS-CoV (EMC2012 strain) N/A Protects all vaccinated hDPP4-Tg mice from challenge of MERS-CoV (EMC2012 strain, 104 TCID50) Du et al., 2016a |
| T251 | 3186-3248 | Sentence | denotes | Subunit vaccines based on non-RBD MERS-CoV S protein fragments |
| T252 | 3249-3286 | Sentence | denotes | S1 protein N/A Ribi; Alum pho I.M. |
| T253 | 3288-3588 | Sentence | denotes | BALB/c mice; NHPs Elicits MERS-CoV S1-specific Abs in mice (IgG and IgG1) and NHPs (IgG), neutralizing 8 pseudotyped and live MERS-CoV (JordanN3 strain) N/A Protects vaccinated NHPs from challenge of MERS-CoV (JordanN3 strain, 5 × 106 PFU) with reduced abnormalities on chest CT Wang et al., 2015 |
| T254 | 3589-3623 | Sentence | denotes | S1 protein N/A Advax + SAS I.M. |
| T255 | 3625-4012 | Sentence | denotes | Dromedary camels; Alpacas Elicits neutralizing Abs in dromedary camels (≥ 1:80) and alpacas (≥ 1:6.4 × 102) against live MERS-CoV (EMC2012 strain) N/A Protects vaccinated dromedary camels and alpacas from challenge of MERS-CoV (EMC2012 strain, 107 TCID50) with reduced and delayed viral shedding in the upper airways (in camels) or complete protection (in alpacas) Adney et al., 2019 |
| T256 | 4013-4052 | Sentence | denotes | rNTD protein N/A Alum pho + CpG I.M. |
| T257 | 4054-4501 | Sentence | denotes | BALB/c mice; Ad5-hDPP4 mice Elicits MERS-CoV S-NTD-specific Abs (IgG, ≥ 1:104) in mice, neutralizing pseudotyped and live (1:40) MERS-CoV (EMC2012 strain) Induces MERS-CoV S-NTD-specific cellular immune responses (IFN-γ, IL-2, IL-6, IL-10, and IL-17A) in mice Protects vaccinated Ad5-hDPP4-transduced mice from challenge of MERS-CoV (EMC2012 strain, 105 PFU) with reduced lung abnormalities and respiratory tract pathology Jiaming et al., 2017 |
| T258 | 4502-4693 | Sentence | denotes | SP3 peptide (aa736-761) N/A Freund’s N/A BALB/c mice; NZW rabbits Elicits MERS-CoV S-specific Abs (IgG, 1:104) in rabbits, neutralizing pseudotyped MERS-CoV N/A N/A Yang et al., 2014a |