PMC:7105881 / 41051-46467
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id | tao:has_standard_notation |
---|---|---|---|---|---|---|
1363 | 277-281 | Gene | denotes | DPP4 | Gene:1803 | |
1364 | 731-735 | Gene | denotes | IgG1 | Gene:16017 | |
1365 | 737-742 | Gene | denotes | IgG2a | Gene:668478 | |
1366 | 748-753 | Gene | denotes | IgG2b | Gene:16016 | |
1367 | 930-935 | Gene | denotes | IFN-γ | Gene:3458 | |
1368 | 937-942 | Gene | denotes | TNF-α | Gene:7124 | |
1369 | 944-948 | Gene | denotes | IL-2 | Gene:3558 | |
1370 | 950-954 | Gene | denotes | IL-4 | Gene:3565 | |
1371 | 956-960 | Gene | denotes | IL-6 | Gene:3569 | |
1372 | 966-971 | Gene | denotes | IL-10 | Gene:3586 | |
1373 | 1205-1209 | Gene | denotes | DPP4 | Gene:1803 | |
1374 | 1332-1336 | Gene | denotes | IgG1 | Gene:16017 | |
1375 | 1338-1343 | Gene | denotes | IgG2a | Gene:668478 | |
1376 | 1349-1353 | Gene | denotes | IgG3 | Gene:3502 | |
1377 | 1481-1486 | Gene | denotes | IFN-γ | Gene:3458 | |
1378 | 1491-1495 | Gene | denotes | IL-2 | Gene:3558 | |
1379 | 1582-1586 | Gene | denotes | DPP4 | Gene:13482 | |
1380 | 1727-1732 | Gene | denotes | hDPP4 | Gene:1803 | |
1381 | 1816-1820 | Gene | denotes | IgG1 | Gene:16017 | |
1382 | 1826-1831 | Gene | denotes | IgG2a | Gene:668478 | |
1383 | 2012-2017 | Gene | denotes | IFN-γ | Gene:3458 | |
1384 | 2022-2026 | Gene | denotes | IL-2 | Gene:3558 | |
1385 | 2061-2066 | Gene | denotes | hDPP4 | Gene:1803 | |
1386 | 2123-2128 | Gene | denotes | hDPP4 | Gene:1803 | |
1387 | 2405-2409 | Gene | denotes | DPP4 | Gene:1803 | |
1388 | 2536-2541 | Gene | denotes | hDPP4 | Gene:1803 | |
1389 | 2600-2604 | Gene | denotes | IgG1 | Gene:16017 | |
1390 | 2610-2615 | Gene | denotes | IgG2a | Gene:668478 | |
1391 | 2761-2766 | Gene | denotes | hDPP4 | Gene:1803 | |
1392 | 2888-2892 | Gene | denotes | DPP4 | Gene:1803 | |
1393 | 3012-3017 | Gene | denotes | hDPP4 | Gene:1803 | |
1394 | 3143-3148 | Gene | denotes | hDPP4 | Gene:1803 | |
1395 | 3402-3406 | Gene | denotes | IgG1 | Gene:16017 | |
1396 | 3612-3636 | Gene | denotes | CT Wang et al., 2015 S1 | Gene:7276 | |
1397 | 4116-4121 | Gene | denotes | hDPP4 | Gene:1803 | |
1398 | 4160-4163 | Gene | denotes | Abs | Gene:51428 | |
1399 | 4315-4320 | Gene | denotes | IFN-γ | Gene:3458 | |
1400 | 4322-4326 | Gene | denotes | IL-2 | Gene:3558 | |
1401 | 4328-4332 | Gene | denotes | IL-6 | Gene:3569 | |
1402 | 4334-4339 | Gene | denotes | IL-10 | Gene:3586 | |
1403 | 4345-4351 | Gene | denotes | IL-17A | Gene:3605 | |
1404 | 4547-4550 | Gene | denotes | SP3 | Gene:6670 | |
1405 | 4386-4391 | Gene | denotes | hDPP4 | Gene:1803 | |
1406 | 4646-4649 | Gene | denotes | Abs | Gene:51428 | |
1407 | 3718-3721 | Gene | denotes | Abs | Gene:72935 | |
1408 | 3381-3384 | Gene | denotes | Abs | Gene:51428 | |
1409 | 3048-3051 | Gene | denotes | Abs | Gene:72935 | |
1410 | 2580-2583 | Gene | denotes | Abs | Gene:51428 | |
1411 | 1788-1791 | Gene | denotes | Abs | Gene:51428 | |
1412 | 1307-1310 | Gene | denotes | Abs | Gene:51428 | |
1413 | 713-716 | Gene | denotes | Abs | Gene:51428 | |
1414 | 428-431 | Gene | denotes | Abs | Gene:72935 | |
1415 | 218-226 | Species | denotes | MERS-CoV | Tax:1335626 | |
1416 | 295-303 | Species | denotes | MERS-CoV | Tax:1335626 | |
1417 | 401-405 | Species | denotes | mice | Tax:10090 | |
1418 | 435-439 | Species | denotes | mice | Tax:10090 | |
1419 | 468-476 | Species | denotes | MERS-CoV | Tax:1335626 | |
1420 | 536-544 | Species | denotes | MERS-CoV | Tax:1335626 | |
1421 | 629-634 | Species | denotes | mouse | Tax:10090 | |
1422 | 671-675 | Species | denotes | mice | Tax:10090 | |
1423 | 691-699 | Species | denotes | MERS-CoV | Tax:1335626 | |
1424 | 797-802 | Species | denotes | mouse | Tax:10090 | |
1425 | 846-854 | Species | denotes | MERS-CoV | Tax:1335626 | |
1426 | 881-889 | Species | denotes | MERS-CoV | Tax:1335626 | |
1427 | 976-980 | Species | denotes | mice | Tax:10090 | |
1428 | 1050-1058 | Species | denotes | MERS-CoV | Tax:1335626 | |
1429 | 1263-1267 | Species | denotes | mice | Tax:10090 | |
1430 | 1277-1285 | Species | denotes | MERS-CoV | Tax:1335626 | |
1431 | 1358-1362 | Species | denotes | mice | Tax:10090 | |
1432 | 1398-1406 | Species | denotes | MERS-CoV | Tax:1335626 | |
1433 | 1433-1441 | Species | denotes | MERS-CoV | Tax:1335626 | |
1434 | 1500-1504 | Species | denotes | mice | Tax:10090 | |
1435 | 1600-1608 | Species | denotes | MERS-CoV | Tax:1335626 | |
1436 | 1721-1725 | Species | denotes | mice | Tax:10090 | |
1437 | 1736-1740 | Species | denotes | mice | Tax:10090 | |
1438 | 1742-1749 | Species | denotes | Rabbits | Tax:9986 | |
1439 | 1759-1767 | Species | denotes | MERS-CoV | Tax:1335626 | |
1440 | 1911-1919 | Species | denotes | MERS-CoV | Tax:1335626 | |
1441 | 1964-1972 | Species | denotes | MERS-CoV | Tax:1335626 | |
1442 | 2031-2035 | Species | denotes | mice | Tax:10090 | |
1443 | 2085-2089 | Species | denotes | mice | Tax:10090 | |
1444 | 2132-2136 | Species | denotes | mice | Tax:10090 | |
1445 | 2142-2150 | Species | denotes | MERS-CoV | Tax:1335626 | |
1446 | 2423-2431 | Species | denotes | MERS-CoV | Tax:1335626 | |
1447 | 2530-2534 | Species | denotes | mice | Tax:10090 | |
1448 | 2545-2549 | Species | denotes | mice | Tax:10090 | |
1449 | 2559-2567 | Species | denotes | MERS-CoV | Tax:1335626 | |
1450 | 2620-2624 | Species | denotes | mice | Tax:10090 | |
1451 | 2691-2699 | Species | denotes | MERS-CoV | Tax:1335626 | |
1452 | 2770-2774 | Species | denotes | mice | Tax:10090 | |
1453 | 2793-2801 | Species | denotes | MERS-CoV | Tax:1335626 | |
1454 | 2897-2905 | Species | denotes | MERS-CoV | Tax:1335626 | |
1455 | 3006-3010 | Species | denotes | mice | Tax:10090 | |
1456 | 3021-3025 | Species | denotes | mice | Tax:10090 | |
1457 | 3069-3073 | Species | denotes | mice | Tax:10090 | |
1458 | 3087-3095 | Species | denotes | MERS-CoV | Tax:1335626 | |
1459 | 3152-3156 | Species | denotes | mice | Tax:10090 | |
1460 | 3175-3183 | Species | denotes | MERS-CoV | Tax:1335626 | |
1461 | 3265-3273 | Species | denotes | MERS-CoV | Tax:1335626 | |
1462 | 3340-3344 | Species | denotes | mice | Tax:10090 | |
1463 | 3360-3368 | Species | denotes | MERS-CoV | Tax:1335626 | |
1464 | 3460-3468 | Species | denotes | MERS-CoV | Tax:1335626 | |
1465 | 3536-3544 | Species | denotes | MERS-CoV | Tax:1335626 | |
1466 | 3670-3679 | Species | denotes | Dromedary | Tax:9838 | |
1467 | 3680-3686 | Species | denotes | camels | Tax:9838 | |
1468 | 3688-3695 | Species | denotes | Alpacas | Tax:30538 | |
1469 | 3725-3734 | Species | denotes | dromedary | Tax:9838 | |
1470 | 3735-3741 | Species | denotes | camels | Tax:9838 | |
1471 | 3755-3762 | Species | denotes | alpacas | Tax:30538 | |
1472 | 3792-3800 | Species | denotes | MERS-CoV | Tax:1335626 | |
1473 | 3844-3853 | Species | denotes | dromedary | Tax:9838 | |
1474 | 3854-3860 | Species | denotes | camels | Tax:9838 | |
1475 | 3865-3872 | Species | denotes | alpacas | Tax:30538 | |
1476 | 3891-3899 | Species | denotes | MERS-CoV | Tax:1335626 | |
1477 | 3994-4000 | Species | denotes | camels | Tax:9838 | |
1478 | 4029-4036 | Species | denotes | alpacas | Tax:30538 | |
1479 | 4106-4110 | Species | denotes | mice | Tax:10090 | |
1480 | 4122-4126 | Species | denotes | mice | Tax:10090 | |
1481 | 4136-4144 | Species | denotes | MERS-CoV | Tax:1335626 | |
1482 | 4182-4186 | Species | denotes | mice | Tax:10090 | |
1483 | 4229-4237 | Species | denotes | MERS-CoV | Tax:1335626 | |
1484 | 4264-4272 | Species | denotes | MERS-CoV | Tax:1335626 | |
1485 | 4356-4360 | Species | denotes | mice | Tax:10090 | |
1486 | 4403-4407 | Species | denotes | mice | Tax:10090 | |
1487 | 4426-4434 | Species | denotes | MERS-CoV | Tax:1335626 | |
1488 | 4599-4603 | Species | denotes | mice | Tax:10090 | |
1489 | 4609-4616 | Species | denotes | rabbits | Tax:9986 | |
1490 | 4626-4634 | Species | denotes | MERS-CoV | Tax:1335626 | |
1491 | 4666-4673 | Species | denotes | rabbits | Tax:9986 | |
1492 | 4700-4708 | Species | denotes | MERS-CoV | Tax:1335626 | |
1493 | 720-724 | Species | denotes | mice | Tax:10090 | |
1494 | 1795-1799 | Species | denotes | mice | Tax:10090 | |
1495 | 1837-1844 | Species | denotes | rabbits | Tax:9986 | |
1496 | 3388-3392 | Species | denotes | mice | Tax:10090 | |
1497 | 1110-1119 | Disease | denotes | pneumonia | MESH:D011014 | |
1498 | 2228-2250 | Disease | denotes | immunological toxicity | MESH:D007154 | |
1499 | 3581-3602 | Disease | denotes | reduced abnormalities | MESH:D015354 | |
1500 | 4474-4492 | Disease | denotes | lung abnormalities | MESH:D008171 | |
1501 | 2854-2859 | Mutation | denotes | T579N | p.T579N |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T244 | 115-123 | Body_part | denotes | Antibody | http://purl.org/sig/ont/fma/fma62871 |
T245 | 241-248 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T246 | 259-266 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T247 | 549-556 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T248 | 573-580 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T249 | 726-729 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T250 | 765-768 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T251 | 944-948 | Body_part | denotes | IL-2 | http://purl.org/sig/ont/fma/fma84051 |
T252 | 1187-1194 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T253 | 1312-1315 | Body_part | denotes | IgA | http://purl.org/sig/ont/fma/fma62874 |
T254 | 1317-1320 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T255 | 1491-1495 | Body_part | denotes | IL-2 | http://purl.org/sig/ont/fma/fma84051 |
T256 | 1564-1571 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T257 | 1801-1804 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T258 | 1846-1849 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T259 | 2022-2026 | Body_part | denotes | IL-2 | http://purl.org/sig/ont/fma/fma84051 |
T260 | 2254-2266 | Body_part | denotes | eosinophilic | http://purl.org/sig/ont/fma/fma62861 |
T261 | 2387-2394 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T262 | 2585-2588 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T263 | 2861-2868 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T264 | 3276-3283 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T265 | 3297-3304 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T266 | 3394-3397 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T267 | 3418-3421 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T268 | 3606-3611 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
T269 | 3637-3644 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T270 | 4063-4070 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T271 | 4165-4168 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T272 | 4322-4326 | Body_part | denotes | IL-2 | http://purl.org/sig/ont/fma/fma84051 |
T273 | 4474-4478 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T274 | 4497-4514 | Body_part | denotes | respiratory tract | http://purl.org/sig/ont/fma/fma265130 |
T275 | 4651-4654 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T276 | 4744-4754 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
T277 | 5343-5349 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T14 | 3606-3611 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
T15 | 4474-4478 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T16 | 4497-4514 | Body_part | denotes | respiratory tract | http://purl.obolibrary.org/obo/UBERON_0000065 |
T17 | 5343-5349 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T232 | 306-309 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
T234 | 1110-1119 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T235 | 2057-2060 | Disease | denotes | Ad5 | http://purl.obolibrary.org/obo/MONDO_0011194 |
T236 | 2384-2386 | Disease | denotes | Fd | http://purl.obolibrary.org/obo/MONDO_0010526 |
T237 | 4112-4115 | Disease | denotes | Ad5 | http://purl.obolibrary.org/obo/MONDO_0011194 |
T238 | 4147-4150 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
T240 | 4275-4278 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
T242 | 4382-4385 | Disease | denotes | Ad5 | http://purl.obolibrary.org/obo/MONDO_0011194 |
T243 | 4773-4776 | Disease | denotes | Ad5 | http://purl.obolibrary.org/obo/MONDO_0011194 |
T244 | 4801-4804 | Disease | denotes | Ad5 | http://purl.obolibrary.org/obo/MONDO_0011194 |
T245 | 4817-4820 | Disease | denotes | Ad5 | http://purl.obolibrary.org/obo/MONDO_0011194 |
T246 | 5358-5368 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
T247 | 5382-5387 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T532 | 100-106 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | Animal |
T533 | 320-322 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
T534 | 320-322 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
T535 | 351-353 | http://purl.obolibrary.org/obo/CLO_0003414 | denotes | G2 |
T536 | 383-386 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAS |
T537 | 480-481 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T538 | 485-486 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T539 | 584-585 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T540 | 629-634 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
T541 | 797-802 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
T542 | 812-815 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
T543 | 841-844 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
T544 | 944-948 | http://purl.obolibrary.org/obo/PR_000001379 | denotes | IL-2 |
T545 | 988-995 | http://purl.obolibrary.org/obo/NCBITaxon_9479 | denotes | monkeys |
T546 | 1184-1186 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T547 | 1286-1288 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T548 | 1388-1391 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
T549 | 1442-1444 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T550 | 1491-1495 | http://purl.obolibrary.org/obo/PR_000001379 | denotes | IL-2 |
T551 | 1508-1509 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T552 | 1561-1563 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T553 | 1768-1770 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T554 | 1808-1813 | http://purl.obolibrary.org/obo/CLO_0001040 | denotes | 1:105 |
T555 | 1973-1975 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T556 | 2022-2026 | http://purl.obolibrary.org/obo/PR_000001379 | denotes | IL-2 |
T557 | 2375-2379 | http://purl.obolibrary.org/obo/CLO_0001185 | denotes | 2018 |
T558 | 2568-2570 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T559 | 2592-2597 | http://purl.obolibrary.org/obo/CLO_0001040 | denotes | 1:105 |
T560 | 2720-2721 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T561 | 3116-3117 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T562 | 3294-3296 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T563 | 3308-3309 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T564 | 3369-3371 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T565 | 3490-3491 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T566 | 3606-3611 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
T567 | 3634-3636 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T568 | 3648-3649 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T569 | 3659-3662 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAS |
T570 | 3680-3686 | http://purl.obolibrary.org/obo/NCBITaxon_9837 | denotes | camels |
T571 | 3735-3741 | http://purl.obolibrary.org/obo/NCBITaxon_9837 | denotes | camels |
T572 | 3774-3777 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
T573 | 3821-3822 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T574 | 3854-3860 | http://purl.obolibrary.org/obo/NCBITaxon_9837 | denotes | camels |
T575 | 3982-3989 | http://purl.obolibrary.org/obo/UBERON_0001005 | denotes | airways |
T576 | 3994-4000 | http://purl.obolibrary.org/obo/NCBITaxon_9837 | denotes | camels |
T577 | 4074-4075 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T578 | 4322-4326 | http://purl.obolibrary.org/obo/PR_000001379 | denotes | IL-2 |
T579 | 4474-4478 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T580 | 4474-4478 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T581 | 4551-4558 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
T582 | 4574-4575 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T583 | 4589-4590 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T584 | 4712-4713 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T585 | 4717-4718 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T586 | 4912-4917 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T587 | 5002-5007 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T588 | 5147-5148 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T589 | 5174-5179 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T590 | 5180-5188 | http://purl.obolibrary.org/obo/NCBITaxon_9443 | denotes | primates |
T591 | 5280-5283 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAS |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T261 | 241-248 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T262 | 259-266 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T263 | 320-322 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
T264 | 364-366 | Chemical | denotes | G4 | http://purl.obolibrary.org/obo/CHEBI_50653 |
T265 | 549-556 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T266 | 573-580 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T267 | 607-616 | Chemical | denotes | poly(I:C) | http://purl.obolibrary.org/obo/CHEBI_84491 |
T268 | 944-946 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T270 | 950-952 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T272 | 956-958 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T274 | 966-968 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T276 | 1187-1194 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T277 | 1491-1493 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T279 | 1564-1571 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T280 | 1733-1735 | Chemical | denotes | Tg | http://purl.obolibrary.org/obo/CHEBI_9516 |
T281 | 2022-2024 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T283 | 2129-2131 | Chemical | denotes | Tg | http://purl.obolibrary.org/obo/CHEBI_9516 |
T284 | 2205-2207 | Chemical | denotes | Tg | http://purl.obolibrary.org/obo/CHEBI_9516 |
T285 | 2387-2394 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T286 | 2542-2544 | Chemical | denotes | Tg | http://purl.obolibrary.org/obo/CHEBI_9516 |
T287 | 2767-2769 | Chemical | denotes | Tg | http://purl.obolibrary.org/obo/CHEBI_9516 |
T288 | 2861-2868 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T289 | 3018-3020 | Chemical | denotes | Tg | http://purl.obolibrary.org/obo/CHEBI_9516 |
T290 | 3149-3151 | Chemical | denotes | Tg | http://purl.obolibrary.org/obo/CHEBI_9516 |
T291 | 3276-3283 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T292 | 3297-3304 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T293 | 3637-3644 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T294 | 4063-4070 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T295 | 4322-4324 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T297 | 4328-4330 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T299 | 4334-4336 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T301 | 4345-4347 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T303 | 4551-4558 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
T304 | 4744-4754 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
T305 | 4744-4749 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
T306 | 4750-4754 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T307 | 4855-4863 | Chemical | denotes | aluminum | http://purl.obolibrary.org/obo/CHEBI_28984 |
T308 | 4864-4873 | Chemical | denotes | hydroxide | http://purl.obolibrary.org/obo/CHEBI_16234 |
T309 | 4894-4903 | Chemical | denotes | phosphate | http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474 |
T313 | 4948-4950 | Chemical | denotes | Tg | http://purl.obolibrary.org/obo/CHEBI_9516 |
T314 | 5039-5047 | Chemical | denotes | adjuvant | http://purl.obolibrary.org/obo/CHEBI_60809 |
T315 | 5410-5415 | Chemical | denotes | alpha | http://purl.obolibrary.org/obo/CHEBI_30216 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T12 | 1110-1119 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T13 | 5382-5387 | Phenotype | denotes | tumor | http://purl.obolibrary.org/obo/HP_0002664 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T77 | 134-158 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | Cellular immune response |
T78 | 134-158 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | Cellular immune response |
T79 | 134-158 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | Cellular immune response |
T80 | 143-158 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
T81 | 903-928 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | cellular immune responses |
T82 | 903-928 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | cellular immune responses |
T83 | 903-928 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | cellular immune responses |
T84 | 1454-1479 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | cellular immune responses |
T85 | 1454-1479 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | cellular immune responses |
T86 | 1454-1479 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | cellular immune responses |
T87 | 1985-2010 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | cellular immune responses |
T88 | 1985-2010 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | cellular immune responses |
T89 | 1985-2010 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | cellular immune responses |
T90 | 3954-3968 | http://purl.obolibrary.org/obo/GO_0019076 | denotes | viral shedding |
T91 | 4288-4313 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | cellular immune responses |
T92 | 4288-4313 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | cellular immune responses |
T93 | 4288-4313 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | cellular immune responses |
T94 | 5388-5396 | http://purl.obolibrary.org/obo/GO_0070265 | denotes | necrosis |
T95 | 5388-5396 | http://purl.obolibrary.org/obo/GO_0019835 | denotes | necrosis |
T96 | 5388-5396 | http://purl.obolibrary.org/obo/GO_0008219 | denotes | necrosis |
T97 | 5388-5396 | http://purl.obolibrary.org/obo/GO_0001906 | denotes | necrosis |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32265848-28807998-36511173 | 505-509 | 28807998 | denotes | 2017 |
32265848-25405618-36511174 | 1158-1162 | 25405618 | denotes | 2014 |
32265848-26629538-36511175 | 1164-1168 | 26629538 | denotes | 2015 |
32265848-25874632-36511180 | 2336-2340 | 25874632 | denotes | 2015 |
32265848-25640653-36511181 | 2356-2360 | 25640653 | denotes | 2016 |
32265848-29496347-36511182 | 2375-2379 | 29496347 | denotes | 2018 |
32265848-27750111-36511183 | 2844-2848 | 27750111 | denotes | 2016 |
32265848-26218507-36511185 | 3629-3633 | 26218507 | denotes | 2015 |
32265848-30832356-36511186 | 4053-4057 | 30832356 | denotes | 2019 |
32265848-27899228-36511187 | 4542-4546 | 27899228 | denotes | 2017 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T235 | 0-44 | Sentence | denotes | TABLE 2 Subunit Vaccines against MERS-CoVa. |
T236 | 45-191 | Sentence | denotes | Name Functionality and antigenicity Adjuvant Route Animal models Antibody response Cellular immune response Protective efficacy References |
T237 | 192-248 | Sentence | denotes | Subunit vaccines based on MERS-CoV full-length S protein |
T238 | 249-392 | Sentence | denotes | MERS S-2P protein Binds to DPP4 receptor and MERS-CoV S-NTD, RBD, and S2-specific neutralizing mAbs (G2, D12, and G4, respectively) SAS I.M. |
T239 | 394-509 | Sentence | denotes | BALB/c mice Elicits neutralizing Abs in mice, neutralizing 7 pseudotyped MERS-CoV N/A N/A Pallesen et al., 2017 |
T240 | 510-556 | Sentence | denotes | Subunit vaccines based on MERS-CoV RBD protein |
T241 | 557-662 | Sentence | denotes | rRBD (S367-606) protein N/A Alum Hydro + CpG or poly(I:C); IFA + CpG (mouse); Alum (NHPs) I.M. or S.C. |
T242 | 664-1168 | Sentence | denotes | BALB/c mice; NHPs Elicits MERS-CoV RBD-specific Abs in mice (IgG, IgG1, IgG2a, and IgG2b) and NHPs (IgG), neutralizing pseudotyped (mouse: < 1:5 × 102) and live (NHPs: < 1:5 × 102) MERS-CoV (EMC2012 strain) Induces MERS-CoV RBD-specific cellular immune responses (IFN-γ, TNF-α, IL-2, IL-4, IL-6, and IL-10) in mice and/or monkeys Partially protects vaccinated NHPs from challenge of MERS-CoV (EMC2012 strain, 6.5 × 107 TCID50) with alleviated pneumonia and decreased viral load Lan et al., 2014, 2015 |
T243 | 1169-1254 | Sentence | denotes | RBD (S377-662)-Fc protein Binds to DPP4 receptor Poly(I:C); Montanide I.N. or S.C. |
T244 | 1256-1545 | Sentence | denotes | BALB/c mice Elicits MERS-CoV S1- and RBD-specific Abs (IgA, IgG (> 1:104), IgG1, IgG2a, and IgG3) in mice, neutralizing (≥ 1:2.4 × 102) live MERS-CoV (EMC2012 strain) Induces MERS-CoV S1-specific cellular immune responses (IFN-γ and IL-2) in mice N/A Du et al., 2013c; Ma et al., 2014b |
T245 | 1546-1712 | Sentence | denotes | RBD (S377-588)-Fc protein Binds to DPP4 receptor and MERS-CoV RBD specific neutralizing mAbs (Mersmab1, m336, m337, and m338) Montanide; MF59; AddaVax I.M. or S.C. |
T246 | 1714-2379 | Sentence | denotes | BALB/c mice; hDPP4-Tg mice; Rabbits Elicits MERS-CoV S1 and RBD-specific Abs in mice (IgG (> 1:105), IgG1, and IgG2a) and rabbits (IgG), neutralizing 17 pseudotyped (≥ 1:104) and 2 live (≥ 1:103) MERS-CoV (EMC2012 and London1-2012 strains) Induces MERS-CoV S1-specific cellular immune responses (IFN-γ and IL-2) in mice Protects vaccinated Ad5/hDPP4-transduced BALB/c mice and majority (4/6) of vaccinated hDPP4-Tg mice from MERS-CoV (EMC2012 strain, 105 PFU for BALB/c; 103–4 TCID50 for Tg) challenge, without immunological toxicity or eosinophilic immune enhancement Du et al., 2013a; Ma et al., 2014b; Tang et al., 2015; Zhang et al., 2016; Nyon et al., 2018 |
T247 | 2380-2521 | Sentence | denotes | RBD-Fd protein Binds to DPP4 receptor and MERS-CoV RBD-specific neutralizing mAbs (Mersmab1, m336, m337, and m338) MF59; Alum I.M. or S.C. |
T248 | 2523-2848 | Sentence | denotes | BALB/c mice; hDPP4-Tg mice Elicits MERS-CoV S1-specific Abs (IgG (> 1:105), IgG1, and IgG2a) in mice, neutralizing at least 9 pseudotyped (> 1:104) and live (> 1:103) MERS-CoV (EMC2012 strain) N/A Protects majority (5/6) of vaccinated hDPP4-Tg mice from challenge of MERS-CoV (EMC2012 strain, 104 TCID50) Tai et al., 2016 |
T249 | 2849-2997 | Sentence | denotes | RBD (T579N) protein Binds to receptor DPP4 and MERS-CoV RBD-specific neutralizing mAbs (hMS-1, m336, m337, and m338) Montanide; Alum I.M. or S.C. |
T250 | 2999-3230 | Sentence | denotes | BALB/c mice; hDPP4-Tg mice Elicits neutralizing Abs (> 1:3 × 103) in mice against live MERS-CoV (EMC2012 strain) N/A Protects all vaccinated hDPP4-Tg mice from challenge of MERS-CoV (EMC2012 strain, 104 TCID50) Du et al., 2016a |
T251 | 3231-3293 | Sentence | denotes | Subunit vaccines based on non-RBD MERS-CoV S protein fragments |
T252 | 3294-3331 | Sentence | denotes | S1 protein N/A Ribi; Alum pho I.M. |
T253 | 3333-3633 | Sentence | denotes | BALB/c mice; NHPs Elicits MERS-CoV S1-specific Abs in mice (IgG and IgG1) and NHPs (IgG), neutralizing 8 pseudotyped and live MERS-CoV (JordanN3 strain) N/A Protects vaccinated NHPs from challenge of MERS-CoV (JordanN3 strain, 5 × 106 PFU) with reduced abnormalities on chest CT Wang et al., 2015 |
T254 | 3634-3668 | Sentence | denotes | S1 protein N/A Advax + SAS I.M. |
T255 | 3670-4057 | Sentence | denotes | Dromedary camels; Alpacas Elicits neutralizing Abs in dromedary camels (≥ 1:80) and alpacas (≥ 1:6.4 × 102) against live MERS-CoV (EMC2012 strain) N/A Protects vaccinated dromedary camels and alpacas from challenge of MERS-CoV (EMC2012 strain, 107 TCID50) with reduced and delayed viral shedding in the upper airways (in camels) or complete protection (in alpacas) Adney et al., 2019 |
T256 | 4058-4097 | Sentence | denotes | rNTD protein N/A Alum pho + CpG I.M. |
T257 | 4099-4546 | Sentence | denotes | BALB/c mice; Ad5-hDPP4 mice Elicits MERS-CoV S-NTD-specific Abs (IgG, ≥ 1:104) in mice, neutralizing pseudotyped and live (1:40) MERS-CoV (EMC2012 strain) Induces MERS-CoV S-NTD-specific cellular immune responses (IFN-γ, IL-2, IL-6, IL-10, and IL-17A) in mice Protects vaccinated Ad5-hDPP4-transduced mice from challenge of MERS-CoV (EMC2012 strain, 105 PFU) with reduced lung abnormalities and respiratory tract pathology Jiaming et al., 2017 |
T258 | 4547-4738 | Sentence | denotes | SP3 peptide (aa736-761) N/A Freund’s N/A BALB/c mice; NZW rabbits Elicits MERS-CoV S-specific Abs (IgG, 1:104) in rabbits, neutralizing pseudotyped MERS-CoV N/A N/A Yang et al., 2014a |
T259 | 4739-5416 | Sentence | denotes | aaa, amino acid; Abs, antibodies; Ad5, adenovirus serotype 5; Ad5-hDPP4 mice, Ad5-hDPP4-transuced mice; Alum hydro, aluminum hydroxide; Alum pho, Aluminum phosphate; hDPP4, human dipeptidyl peptidase 4; hDPP4-Tg mice, transgenic mice expressing MERS-CoV receptor human DPP4; IFA, incomplete Freund’s adjuvant; I.M., intramuscular; I.N., intranasal; mAbs, monoclonal antibodies; Montanide, Montanide ISA51; N/A, not reported; NHPs, non-human primates; NZW, rabbits, New Zealand White rabbits; PFU, plaque-forming unit; rRBD, recombinant RBD; SAS, Sigma Adjuvant System; S.C., subcutaneous; TCID50, median tissue culture infectious dose; TNF-α, tumor necrosis factor (TNF)-alpha. |
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T733 | 34-38 | SP_9 | denotes | MERS |
T19177 | 34-38 | SP_9 | denotes | MERS |