PMC:7105881 / 33516-33837 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"1083","span":{"begin":109,"end":113},"obj":"Gene"},{"id":"1084","span":{"begin":298,"end":302},"obj":"Gene"},{"id":"1087","span":{"begin":178,"end":186},"obj":"Species"},{"id":"1088","span":{"begin":204,"end":211},"obj":"Species"},{"id":"1089","span":{"begin":216,"end":220},"obj":"Species"},{"id":"1090","span":{"begin":280,"end":288},"obj":"Species"},{"id":"1103","span":{"begin":103,"end":108},"obj":"Species"}],"attributes":[{"id":"A1083","pred":"tao:has_database_id","subj":"1083","obj":"Gene:16017"},{"id":"A1084","pred":"tao:has_database_id","subj":"1084","obj":"Gene:59272"},{"id":"A1087","pred":"tao:has_database_id","subj":"1087","obj":"Tax:694009"},{"id":"A1088","pred":"tao:has_database_id","subj":"1088","obj":"Tax:9986"},{"id":"A1089","pred":"tao:has_database_id","subj":"1089","obj":"Tax:10090"},{"id":"A1090","pred":"tao:has_database_id","subj":"1090","obj":"Tax:694009"},{"id":"A1103","pred":"tao:has_database_id","subj":"1103","obj":"Tax:9606"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Studies have found that a fusion protein containing RBD and the fragment crystallizable (Fc) region of human IgG1 (RBD-Fc) elicited highly potent neutralizing antibodies against SARS-CoV in the immunized rabbits and mice, which strongly blocked the binding between S1 protein and SARS-CoV receptor ACE2 (He et al., 2004)."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T188","span":{"begin":33,"end":40},"obj":"Body_part"},{"id":"T189","span":{"begin":268,"end":275},"obj":"Body_part"}],"attributes":[{"id":"A188","pred":"fma_id","subj":"T188","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A189","pred":"fma_id","subj":"T189","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"Studies have found that a fusion protein containing RBD and the fragment crystallizable (Fc) region of human IgG1 (RBD-Fc) elicited highly potent neutralizing antibodies against SARS-CoV in the immunized rabbits and mice, which strongly blocked the binding between S1 protein and SARS-CoV receptor ACE2 (He et al., 2004)."}

{"project":"LitCovid_AGAC","denotations":[{"id":"p63076s43","span":{"begin":237,"end":244},"obj":"NegReg"},{"id":"p63076s45","span":{"begin":249,"end":256},"obj":"Interaction"},{"id":"p63076s50","span":{"begin":280,"end":302},"obj":"MPA"}],"text":"Studies have found that a fusion protein containing RBD and the fragment crystallizable (Fc) region of human IgG1 (RBD-Fc) elicited highly potent neutralizing antibodies against SARS-CoV in the immunized rabbits and mice, which strongly blocked the binding between S1 protein and SARS-CoV receptor ACE2 (He et al., 2004)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T180","span":{"begin":178,"end":186},"obj":"Disease"},{"id":"T181","span":{"begin":280,"end":288},"obj":"Disease"}],"attributes":[{"id":"A180","pred":"mondo_id","subj":"T180","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A181","pred":"mondo_id","subj":"T181","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Studies have found that a fusion protein containing RBD and the fragment crystallizable (Fc) region of human IgG1 (RBD-Fc) elicited highly potent neutralizing antibodies against SARS-CoV in the immunized rabbits and mice, which strongly blocked the binding between S1 protein and SARS-CoV receptor ACE2 (He et al., 2004)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T441","span":{"begin":24,"end":25},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T442","span":{"begin":89,"end":91},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T443","span":{"begin":103,"end":108},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T444","span":{"begin":119,"end":121},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T445","span":{"begin":265,"end":267},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"}],"text":"Studies have found that a fusion protein containing RBD and the fragment crystallizable (Fc) region of human IgG1 (RBD-Fc) elicited highly potent neutralizing antibodies against SARS-CoV in the immunized rabbits and mice, which strongly blocked the binding between S1 protein and SARS-CoV receptor ACE2 (He et al., 2004)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T196","span":{"begin":33,"end":40},"obj":"Chemical"},{"id":"T197","span":{"begin":268,"end":275},"obj":"Chemical"}],"attributes":[{"id":"A196","pred":"chebi_id","subj":"T196","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A197","pred":"chebi_id","subj":"T197","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"Studies have found that a fusion protein containing RBD and the fragment crystallizable (Fc) region of human IgG1 (RBD-Fc) elicited highly potent neutralizing antibodies against SARS-CoV in the immunized rabbits and mice, which strongly blocked the binding between S1 protein and SARS-CoV receptor ACE2 (He et al., 2004)."}

{"project":"2_test","denotations":[{"id":"32265848-15474494-36511140","span":{"begin":315,"end":319},"obj":"15474494"}],"text":"Studies have found that a fusion protein containing RBD and the fragment crystallizable (Fc) region of human IgG1 (RBD-Fc) elicited highly potent neutralizing antibodies against SARS-CoV in the immunized rabbits and mice, which strongly blocked the binding between S1 protein and SARS-CoV receptor ACE2 (He et al., 2004)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T200","span":{"begin":0,"end":321},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Studies have found that a fusion protein containing RBD and the fragment crystallizable (Fc) region of human IgG1 (RBD-Fc) elicited highly potent neutralizing antibodies against SARS-CoV in the immunized rabbits and mice, which strongly blocked the binding between S1 protein and SARS-CoV receptor ACE2 (He et al., 2004)."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T561","span":{"begin":103,"end":108},"obj":"SP_6;NCBITaxon:9606"},{"id":"T562","span":{"begin":109,"end":113},"obj":"GO:0071735"},{"id":"T563","span":{"begin":159,"end":169},"obj":"GO:0042571"},{"id":"T564","span":{"begin":178,"end":186},"obj":"SP_10"},{"id":"T565","span":{"begin":204,"end":211},"obj":"NCBITaxon:9986"},{"id":"T566","span":{"begin":216,"end":220},"obj":"NCBITaxon:10088"},{"id":"T567","span":{"begin":280,"end":288},"obj":"SP_10"},{"id":"T568","span":{"begin":298,"end":302},"obj":"G_3;PG_10;PR:000003622"},{"id":"T51408","span":{"begin":103,"end":108},"obj":"SP_6;NCBITaxon:9606"},{"id":"T32600","span":{"begin":109,"end":113},"obj":"GO:0071735"},{"id":"T99084","span":{"begin":159,"end":169},"obj":"GO:0042571"},{"id":"T60337","span":{"begin":178,"end":186},"obj":"SP_10"},{"id":"T29995","span":{"begin":204,"end":211},"obj":"NCBITaxon:9986"},{"id":"T6206","span":{"begin":216,"end":220},"obj":"NCBITaxon:10088"},{"id":"T53931","span":{"begin":280,"end":288},"obj":"SP_10"},{"id":"T59081","span":{"begin":298,"end":302},"obj":"G_3;PG_10;PR:000003622"}],"text":"Studies have found that a fusion protein containing RBD and the fragment crystallizable (Fc) region of human IgG1 (RBD-Fc) elicited highly potent neutralizing antibodies against SARS-CoV in the immunized rabbits and mice, which strongly blocked the binding between S1 protein and SARS-CoV receptor ACE2 (He et al., 2004)."}